1D7WC

Crystal structure of human myeloperoxidase isoform c complexed with cyanide and bromide at ph 4.0
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
466
structure length
465
Chain Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
publication title Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
pubmed doi rcsb
molecule keywords MYELOPEROXIDASE
total genus 145
structure length 465
sequence length 466
chains with identical sequence D
ec nomenclature ec 1.11.2.2: Myeloperoxidase.
pdb deposition date 1999-10-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 1d7wC00
4HHSA 4C1MC 4RS0A 3F9PC 3NTGA 4HHRA 1PRHA 3KRKA 2QPKA 1D5LC 3N8XA 3HS5A 4GM7A 2EHAA 5GH0A 5GLSA 3LN1A 3NTBA 1IGZA 1PTHA 1CQEA 4KVLA 2OYUP 4COXA 4NJBA 1HT5A 4RRWA 5IKTA 3S4FA 4OTYA 4GN6A 3KK6A 4MSFA 1DDXA 5HPWA 5B72A 3R4XA 1EBVA 3R5QA 4RRZA 1CVUA 3OLTA 2E9EA 2PUMA 3MQEA 3FNLA 4LJJA 3RR3A 3N8ZA 3QL6A 1PGEA 4RUTA 1IGXA 1EQGA 3FAQA 3TGYA 5IKQA 1Q4GA 3QF1A 5COXA 3MDLA 4PNXA 4Z0LA 3OGWA 3GCKA 4QYQA 3ERHA 1PXXA 3RKEA 5JVZA 4N7AA 2PT3A 3R55A 6COXA 3GC1A 3Q7DA 4OEKA 3N8WB 1DNUC 4M11A 2IPSA 2OJVA 3TZIA 2AYLA 1CX2A 3QMOA 4NT3A 1D2VC 2O86A 3NYHA 3N8WA 4Y55A 3NAKA 5F1AA 3ERIA 4DL1C 3N8YB 3QH0A 4KVKA 2OYEP 5IKRA 1FE2A 3ZS1C 3N8VA 3HS6A 4QJQA 2QQTA 4OTJA 4KSZA 3GCJA 3N8YA 5FDQA 3OLUA 3R5OA 1D7WC 2Z5ZA 1DIYA 4RRXA 5KIRA 4O1ZA 2NQXA 1HT8A 3LN0A 4FM5A 3N8FA 2GJMA 3NIUA 1U67A 4KVJA 5JW1A 1MHLC 3GCLA 5FIWC 5F19A 5IKVA 3BXIA 3SXVA 5FF1A 1MYPC 2EFBA 1DNWC 1CXPC 3V6QA 4E1GA 3Q9KA 3ZS0C 3PY4A 4IG5A 4M10A 2R5LA 3I6NA 2QRBA 5JVYA 3HS7A 3KRQA 3PGHA 3NT1A 4RRYA 2IKCA 3UBAA 4PH9A 1EQHA
chains in the Genus database with same CATH superfamily
4HHSA 4C1MC 4RS0A 3F9PC 3NTGA 4HHRA 1PRHA 3KRKA 2QPKA 1D5LC 3N8XA 3HS5A 4GM7A 2EHAA 5GH0A 5GLSA 3LN1A 3NTBA 1IGZA 1PTHA 1CQEA 4KVLA 2OYUP 4COXA 4NJBA 1HT5A 4RRWA 5IKTA 3S4FA 4OTYA 4GN6A 3KK6A 4MSFA 1DDXA 5HPWA 5B72A 3R4XA 1EBVA 3R5QA 4RRZA 1CVUA 3OLTA 2E9EA 2PUMA 3MQEA 3FNLA 4LJJA 3RR3A 3N8ZA 3QL6A 1PGEA 4RUTA 1IGXA 1EQGA 3FAQA 3TGYA 5IKQA 1Q4GA 3QF1A 5COXA 3MDLA 4PNXA 4Z0LA 3OGWA 3GCKA 4QYQA 3ERHA 1PXXA 3RKEA 5JVZA 4N7AA 2PT3A 3R55A 6COXA 3GC1A 3Q7DA 4OEKA 3N8WB 1DNUC 4M11A 2IPSA 2OJVA 3TZIA 2AYLA 1CX2A 3QMOA 4NT3A 1D2VC 2O86A 3NYHA 3N8WA 4Y55A 3NAKA 5F1AA 3ERIA 4DL1C 3N8YB 3QH0A 4KVKA 2OYEP 5IKRA 1FE2A 3ZS1C 3N8VA 3HS6A 4QJQA 2QQTA 4OTJA 4KSZA 3GCJA 3N8YA 5FDQA 3OLUA 3R5OA 1D7WC 2Z5ZA 1DIYA 4RRXA 5KIRA 4O1ZA 2NQXA 1HT8A 3LN0A 4FM5A 3N8FA 2GJMA 3NIUA 1U67A 4KVJA 5JW1A 1MHLC 3GCLA 5FIWC 5F19A 5IKVA 3BXIA 3SXVA 5FF1A 1MYPC 2EFBA 1DNWC 1CXPC 3V6QA 4E1GA 3Q9KA 3ZS0C 3PY4A 4IG5A 4M10A 2R5LA 3I6NA 2QRBA 5JVYA 3HS7A 3KRQA 3PGHA 3NT1A 4RRYA 2IKCA 3UBAA 4PH9A 1EQHA
chains in the Genus database with same CATH topology
4HHSA 4C1MC 4RS0A 3F9PC 3NTGA 4HHRA 1PRHA 3KRKA 2QPKA 1D5LC 3N8XA 3HS5A 4GM7A 2EHAA 5GH0A 5GLSA 3LN1A 3NTBA 1IGZA 1PTHA 1CQEA 4KVLA 2OYUP 4COXA 4NJBA 1HT5A 4RRWA 5IKTA 3S4FA 4OTYA 4GN6A 3KK6A 4MSFA 1DDXA 5HPWA 5B72A 3R4XA 1EBVA 3R5QA 4RRZA 1CVUA 3OLTA 2E9EA 2PUMA 3MQEA 3FNLA 4LJJA 3RR3A 3N8ZA 3QL6A 1PGEA 4RUTA 1IGXA 1EQGA 3FAQA 3TGYA 5IKQA 1Q4GA 3QF1A 5COXA 3MDLA 4PNXA 4Z0LA 3OGWA 3GCKA 4QYQA 3ERHA 1PXXA 3RKEA 5JVZA 4N7AA 2PT3A 3R55A 6COXA 3GC1A 3Q7DA 4OEKA 3N8WB 1DNUC 4M11A 2IPSA 2OJVA 3TZIA 2AYLA 1CX2A 3QMOA 4NT3A 1D2VC 2O86A 3NYHA 3N8WA 4Y55A 3NAKA 5F1AA 3ERIA 4DL1C 3N8YB 3QH0A 4KVKA 2OYEP 5IKRA 1FE2A 3ZS1C 3N8VA 3HS6A 4QJQA 2QQTA 4OTJA 4KSZA 3GCJA 3N8YA 5FDQA 3OLUA 3R5OA 1D7WC 2Z5ZA 1DIYA 4RRXA 5KIRA 4O1ZA 2NQXA 1HT8A 3LN0A 4FM5A 3N8FA 2GJMA 3NIUA 1U67A 4KVJA 5JW1A 1MHLC 3GCLA 5FIWC 5F19A 5IKVA 3BXIA 3SXVA 5FF1A 1MYPC 2EFBA 1DNWC 1CXPC 3V6QA 4E1GA 3Q9KA 3ZS0C 3PY4A 4IG5A 4M10A 2R5LA 3I6NA 2QRBA 5JVYA 3HS7A 3KRQA 3PGHA 3NT1A 4RRYA 2IKCA 3UBAA 4PH9A 1EQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HHS A;  4C1M C;  4RS0 A;  3F9P C;  3NTG A;  4HHR A;  1PRH A;  3KRK A;  2QPK A;  1D5L C;  3N8X A;  3HS5 A;  4GM7 A;  2EHA A;  5GH0 A;  5GLS A;  3LN1 A;  3NTB A;  1IGZ A;  1PTH A;  1CQE A;  4KVL A;  2OYU P;  4COX A;  4NJB A;  1HT5 A;  4RRW A;  5IKT A;  3S4F A;  4OTY A;  4GN6 A;  3KK6 A;  4MSF A;  1DDX A;  5HPW A;  5B72 A;  3R4X A;  1EBV A;  3R5Q A;  4RRZ A;  1CVU A;  3OLT A;  2E9E A;  2PUM A;  3MQE A;  3FNL A;  4LJJ A;  3RR3 A;  3N8Z A;  3QL6 A;  1PGE A;  4RUT A;  1IGX A;  1EQG A;  3FAQ A;  3TGY A;  5IKQ A;  1Q4G A;  3QF1 A;  5COX A;  3MDL A;  4PNX A;  4Z0L A;  3OGW A;  3GCK A;  4QYQ A;  3ERH A;  1PXX A;  3RKE A;  5JVZ A;  4N7A A;  2PT3 A;  3R55 A;  6COX A;  3GC1 A;  3Q7D A;  4OEK A;  3N8W B;  1DNU C;  4M11 A;  2IPS A;  2OJV A;  3TZI A;  2AYL A;  1CX2 A;  3QMO A;  4NT3 A;  1D2V C;  2O86 A;  3NYH A;  3N8W A;  4Y55 A;  3NAK A;  5F1A A;  3ERI A;  4DL1 C;  3N8Y B;  3QH0 A;  4KVK A;  2OYE P;  5IKR A;  1FE2 A;  3ZS1 C;  3N8V A;  3HS6 A;  4QJQ A;  2QQT A;  4OTJ A;  4KSZ A;  3GCJ A;  3N8Y A;  5FDQ A;  3OLU A;  3R5O A;  1D7W C;  2Z5Z A;  1DIY A;  4RRX A;  5KIR A;  4O1Z A;  2NQX A;  1HT8 A;  3LN0 A;  4FM5 A;  3N8F A;  2GJM A;  3NIU A;  1U67 A;  4KVJ A;  5JW1 A;  1MHL C;  3GCL A;  5FIW C;  5F19 A;  5IKV A;  3BXI A;  3SXV A;  5FF1 A;  1MYP C;  2EFB A;  1DNW C;  1CXP C;  3V6Q A;  4E1G A;  3Q9K A;  3ZS0 C;  3PY4 A;  4IG5 A;  4M10 A;  2R5L A;  3I6N A;  2QRB A;  5JVY A;  3HS7 A;  3KRQ A;  3PGH A;  3NT1 A;  4RRY A;  2IKC A;  3UBA A;  4PH9 A;  1EQH A; 
#chains in the Genus database with same CATH topology
 4HHS A;  4C1M C;  4RS0 A;  3F9P C;  3NTG A;  4HHR A;  1PRH A;  3KRK A;  2QPK A;  1D5L C;  3N8X A;  3HS5 A;  4GM7 A;  2EHA A;  5GH0 A;  5GLS A;  3LN1 A;  3NTB A;  1IGZ A;  1PTH A;  1CQE A;  4KVL A;  2OYU P;  4COX A;  4NJB A;  1HT5 A;  4RRW A;  5IKT A;  3S4F A;  4OTY A;  4GN6 A;  3KK6 A;  4MSF A;  1DDX A;  5HPW A;  5B72 A;  3R4X A;  1EBV A;  3R5Q A;  4RRZ A;  1CVU A;  3OLT A;  2E9E A;  2PUM A;  3MQE A;  3FNL A;  4LJJ A;  3RR3 A;  3N8Z A;  3QL6 A;  1PGE A;  4RUT A;  1IGX A;  1EQG A;  3FAQ A;  3TGY A;  5IKQ A;  1Q4G A;  3QF1 A;  5COX A;  3MDL A;  4PNX A;  4Z0L A;  3OGW A;  3GCK A;  4QYQ A;  3ERH A;  1PXX A;  3RKE A;  5JVZ A;  4N7A A;  2PT3 A;  3R55 A;  6COX A;  3GC1 A;  3Q7D A;  4OEK A;  3N8W B;  1DNU C;  4M11 A;  2IPS A;  2OJV A;  3TZI A;  2AYL A;  1CX2 A;  3QMO A;  4NT3 A;  1D2V C;  2O86 A;  3NYH A;  3N8W A;  4Y55 A;  3NAK A;  5F1A A;  3ERI A;  4DL1 C;  3N8Y B;  3QH0 A;  4KVK A;  2OYE P;  5IKR A;  1FE2 A;  3ZS1 C;  3N8V A;  3HS6 A;  4QJQ A;  2QQT A;  4OTJ A;  4KSZ A;  3GCJ A;  3N8Y A;  5FDQ A;  3OLU A;  3R5O A;  1D7W C;  2Z5Z A;  1DIY A;  4RRX A;  5KIR A;  4O1Z A;  2NQX A;  1HT8 A;  3LN0 A;  4FM5 A;  3N8F A;  2GJM A;  3NIU A;  1U67 A;  4KVJ A;  5JW1 A;  1MHL C;  3GCL A;  5FIW C;  5F19 A;  5IKV A;  3BXI A;  3SXV A;  5FF1 A;  1MYP C;  2EFB A;  1DNW C;  1CXP C;  3V6Q A;  4E1G A;  3Q9K A;  3ZS0 C;  3PY4 A;  4IG5 A;  4M10 A;  2R5L A;  3I6N A;  2QRB A;  5JVY A;  3HS7 A;  3KRQ A;  3PGH A;  3NT1 A;  4RRY A;  2IKC A;  3UBA A;  4PH9 A;  1EQH A; 
#chains in the Genus database with same CATH homology
 4HHS A;  4C1M C;  4RS0 A;  3F9P C;  3NTG A;  4HHR A;  1PRH A;  3KRK A;  2QPK A;  1D5L C;  3N8X A;  3HS5 A;  4GM7 A;  2EHA A;  5GH0 A;  5GLS A;  3LN1 A;  3NTB A;  1IGZ A;  1PTH A;  1CQE A;  4KVL A;  2OYU P;  4COX A;  4NJB A;  1HT5 A;  4RRW A;  5IKT A;  3S4F A;  4OTY A;  4GN6 A;  3KK6 A;  4MSF A;  1DDX A;  5HPW A;  5B72 A;  3R4X A;  1EBV A;  3R5Q A;  4RRZ A;  1CVU A;  3OLT A;  2E9E A;  2PUM A;  3MQE A;  3FNL A;  4LJJ A;  3RR3 A;  3N8Z A;  3QL6 A;  1PGE A;  4RUT A;  1IGX A;  1EQG A;  3FAQ A;  3TGY A;  5IKQ A;  1Q4G A;  3QF1 A;  5COX A;  3MDL A;  4PNX A;  4Z0L A;  3OGW A;  3GCK A;  4QYQ A;  3ERH A;  1PXX A;  3RKE A;  5JVZ A;  4N7A A;  2PT3 A;  3R55 A;  6COX A;  3GC1 A;  3Q7D A;  4OEK A;  3N8W B;  1DNU C;  4M11 A;  2IPS A;  2OJV A;  3TZI A;  2AYL A;  1CX2 A;  3QMO A;  4NT3 A;  1D2V C;  2O86 A;  3NYH A;  3N8W A;  4Y55 A;  3NAK A;  5F1A A;  3ERI A;  4DL1 C;  3N8Y B;  3QH0 A;  4KVK A;  2OYE P;  5IKR A;  1FE2 A;  3ZS1 C;  3N8V A;  3HS6 A;  4QJQ A;  2QQT A;  4OTJ A;  4KSZ A;  3GCJ A;  3N8Y A;  5FDQ A;  3OLU A;  3R5O A;  1D7W C;  2Z5Z A;  1DIY A;  4RRX A;  5KIR A;  4O1Z A;  2NQX A;  1HT8 A;  3LN0 A;  4FM5 A;  3N8F A;  2GJM A;  3NIU A;  1U67 A;  4KVJ A;  5JW1 A;  1MHL C;  3GCL A;  5FIW C;  5F19 A;  5IKV A;  3BXI A;  3SXV A;  5FF1 A;  1MYP C;  2EFB A;  1DNW C;  1CXP C;  3V6Q A;  4E1G A;  3Q9K A;  3ZS0 C;  3PY4 A;  4IG5 A;  4M10 A;  2R5L A;  3I6N A;  2QRB A;  5JVY A;  3HS7 A;  3KRQ A;  3PGH A;  3NT1 A;  4RRY A;  2IKC A;  3UBA A;  4PH9 A;  1EQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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