1D7WC

Crystal structure of human myeloperoxidase isoform c complexed with cyanide and bromide at ph 4.0
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
466
structure length
465
Chain Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords MYELOPEROXIDASE
total genus 145
structure length 465
sequence length 466
chains with identical sequence D
ec nomenclature ec 1.11.2.2: Myeloperoxidase.
pdb deposition date 1999-10-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 1d7wC00
1HT8A 3KRKA 1PGEA 2QQTA 2O86A 1DIYA 3NTGA 4KVJA 2OYEP 5IKVA 4QYQA 3N8FA 4RUTA 4PNXA 4M11A 3R5QA 5JVZA 2IPSA 3N8WB 1MYPC 3UBAA 5JVYA 3Q9KA 1D7WC 5F1AA 3NIUA 6COXA 5IKRA 3RR3A 3BXIA 3HS7A 1DDXA 3GC1A 3OLUA 3HS6A 1EQHA 1IGZA 4HHRA 1PRHA 3ZS1C 2EFBA 2NQXA 1MHLC 3NYHA 3NTBA 2Z5ZA 4M10A 3V6QA 3MQEA 1DNWC 1CVUA 2OYUP 4RRXA 5F19A 5FDQA 1EQGA 4E1GA 5IKQA 4MSFA 3ZS0C 2E9EA 1EBVA 4O1ZA 4GN6A 1CXPC 3KRQA 1DNUC 4QJQA 4DL1C 3ERIA 1IGXA 3LN0A 3R4XA 4NT3A 3PGHA 2EHAA 3TZIA 4LJJA 4RRYA 3HS5A 4COXA 3OLTA 3I6NA 3N8YA 3N8YB 3GCJA 5IKTA 2OJVA 1CX2A 3N8XA 4IG5A 1FE2A 2GJMA 4KVKA 4N7AA 3NAKA 3QMOA 3OGWA 1D5LC 2QPKA 4OEKA 3FNLA 4KSZA 4OTJA 3GCKA 5KIRA 4C1MC 1PTHA 3R55A 5GH0A 4RRZA 1Q4GA 5GLSA 3TGYA 4Y55A 2IKCA 1U67A 5B72A 3R5OA 5FIWC 1HT5A 4PH9A 2PUMA 2AYLA 3LN1A 4GM7A 1CQEA 4NJBA 4RS0A 4Z0LA 4FM5A 3QF1A 5FF1A 4HHSA 2PT3A 3N8WA 4RRWA 3KK6A 3NT1A 3RKEA 4OTYA 3FAQA 1PXXA 2QRBA 3MDLA 3F9PC 3S4FA 3ERHA 3N8VA 1D2VC 3N8ZA 5JW1A 3GCLA 3Q7DA 5COXA 3QH0A 4KVLA 3PY4A 5HPWA 3QL6A 2R5LA 3SXVA
chains in the Genus database with same CATH superfamily
1HT8A 3KRKA 1PGEA 2QQTA 2O86A 1DIYA 3NTGA 4KVJA 2OYEP 5IKVA 4QYQA 3N8FA 4RUTA 4PNXA 4M11A 3R5QA 5JVZA 2IPSA 3N8WB 1MYPC 3UBAA 5JVYA 3Q9KA 1D7WC 5F1AA 3NIUA 6COXA 5IKRA 3RR3A 3BXIA 3HS7A 1DDXA 3GC1A 3OLUA 3HS6A 1EQHA 1IGZA 4HHRA 1PRHA 3ZS1C 2EFBA 2NQXA 1MHLC 3NYHA 3NTBA 2Z5ZA 4M10A 3V6QA 3MQEA 1DNWC 1CVUA 2OYUP 4RRXA 5F19A 5FDQA 1EQGA 4E1GA 5IKQA 4MSFA 3ZS0C 2E9EA 1EBVA 4O1ZA 4GN6A 1CXPC 3KRQA 1DNUC 4QJQA 4DL1C 3ERIA 1IGXA 3LN0A 3R4XA 4NT3A 3PGHA 2EHAA 3TZIA 4LJJA 4RRYA 3HS5A 4COXA 3OLTA 3I6NA 3N8YA 3N8YB 3GCJA 5IKTA 2OJVA 1CX2A 3N8XA 4IG5A 1FE2A 2GJMA 4KVKA 4N7AA 3NAKA 3QMOA 3OGWA 1D5LC 2QPKA 4OEKA 3FNLA 4KSZA 4OTJA 3GCKA 5KIRA 4C1MC 1PTHA 3R55A 5GH0A 4RRZA 1Q4GA 5GLSA 3TGYA 4Y55A 2IKCA 1U67A 5B72A 3R5OA 5FIWC 1HT5A 4PH9A 2PUMA 2AYLA 3LN1A 4GM7A 1CQEA 4NJBA 4RS0A 4Z0LA 4FM5A 3QF1A 5FF1A 4HHSA 2PT3A 3N8WA 4RRWA 3KK6A 3NT1A 3RKEA 4OTYA 3FAQA 1PXXA 2QRBA 3MDLA 3F9PC 3S4FA 3ERHA 3N8VA 1D2VC 3N8ZA 5JW1A 3GCLA 3Q7DA 5COXA 3QH0A 4KVLA 3PY4A 5HPWA 3QL6A 2R5LA 3SXVA
chains in the Genus database with same CATH topology
1HT8A 3KRKA 1PGEA 2QQTA 2O86A 1DIYA 3NTGA 4KVJA 2OYEP 5IKVA 4QYQA 3N8FA 4RUTA 4PNXA 4M11A 3R5QA 5JVZA 2IPSA 3N8WB 1MYPC 3UBAA 5JVYA 3Q9KA 1D7WC 5F1AA 3NIUA 6COXA 5IKRA 3RR3A 3BXIA 3HS7A 1DDXA 3GC1A 3OLUA 3HS6A 1EQHA 1IGZA 4HHRA 1PRHA 3ZS1C 2EFBA 2NQXA 1MHLC 3NYHA 3NTBA 2Z5ZA 4M10A 3V6QA 3MQEA 1DNWC 1CVUA 2OYUP 4RRXA 5F19A 5FDQA 1EQGA 4E1GA 5IKQA 4MSFA 3ZS0C 2E9EA 1EBVA 4O1ZA 4GN6A 1CXPC 3KRQA 1DNUC 4QJQA 4DL1C 3ERIA 1IGXA 3LN0A 3R4XA 4NT3A 3PGHA 2EHAA 3TZIA 4LJJA 4RRYA 3HS5A 4COXA 3OLTA 3I6NA 3N8YA 3N8YB 3GCJA 5IKTA 2OJVA 1CX2A 3N8XA 4IG5A 1FE2A 2GJMA 4KVKA 4N7AA 3NAKA 3QMOA 3OGWA 1D5LC 2QPKA 4OEKA 3FNLA 4KSZA 4OTJA 3GCKA 5KIRA 4C1MC 1PTHA 3R55A 5GH0A 4RRZA 1Q4GA 5GLSA 3TGYA 4Y55A 2IKCA 1U67A 5B72A 3R5OA 5FIWC 1HT5A 4PH9A 2PUMA 2AYLA 3LN1A 4GM7A 1CQEA 4NJBA 4RS0A 4Z0LA 4FM5A 3QF1A 5FF1A 4HHSA 2PT3A 3N8WA 4RRWA 3KK6A 3NT1A 3RKEA 4OTYA 3FAQA 1PXXA 2QRBA 3MDLA 3F9PC 3S4FA 3ERHA 3N8VA 1D2VC 3N8ZA 5JW1A 3GCLA 3Q7DA 5COXA 3QH0A 4KVLA 3PY4A 5HPWA 3QL6A 2R5LA 3SXVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HT8 A;  3KRK A;  1PGE A;  2QQT A;  2O86 A;  1DIY A;  3NTG A;  4KVJ A;  2OYE P;  5IKV A;  4QYQ A;  3N8F A;  4RUT A;  4PNX A;  4M11 A;  3R5Q A;  5JVZ A;  2IPS A;  3N8W B;  1MYP C;  3UBA A;  5JVY A;  3Q9K A;  1D7W C;  5F1A A;  3NIU A;  6COX A;  5IKR A;  3RR3 A;  3BXI A;  3HS7 A;  1DDX A;  3GC1 A;  3OLU A;  3HS6 A;  1EQH A;  1IGZ A;  4HHR A;  1PRH A;  3ZS1 C;  2EFB A;  2NQX A;  1MHL C;  3NYH A;  3NTB A;  2Z5Z A;  4M10 A;  3V6Q A;  3MQE A;  1DNW C;  1CVU A;  2OYU P;  4RRX A;  5F19 A;  5FDQ A;  1EQG A;  4E1G A;  5IKQ A;  4MSF A;  3ZS0 C;  2E9E A;  1EBV A;  4O1Z A;  4GN6 A;  1CXP C;  3KRQ A;  1DNU C;  4QJQ A;  4DL1 C;  3ERI A;  1IGX A;  3LN0 A;  3R4X A;  4NT3 A;  3PGH A;  2EHA A;  3TZI A;  4LJJ A;  4RRY A;  3HS5 A;  4COX A;  3OLT A;  3I6N A;  3N8Y A;  3N8Y B;  3GCJ A;  5IKT A;  2OJV A;  1CX2 A;  3N8X A;  4IG5 A;  1FE2 A;  2GJM A;  4KVK A;  4N7A A;  3NAK A;  3QMO A;  3OGW A;  1D5L C;  2QPK A;  4OEK A;  3FNL A;  4KSZ A;  4OTJ A;  3GCK A;  5KIR A;  4C1M C;  1PTH A;  3R55 A;  5GH0 A;  4RRZ A;  1Q4G A;  5GLS A;  3TGY A;  4Y55 A;  2IKC A;  1U67 A;  5B72 A;  3R5O A;  5FIW C;  1HT5 A;  4PH9 A;  2PUM A;  2AYL A;  3LN1 A;  4GM7 A;  1CQE A;  4NJB A;  4RS0 A;  4Z0L A;  4FM5 A;  3QF1 A;  5FF1 A;  4HHS A;  2PT3 A;  3N8W A;  4RRW A;  3KK6 A;  3NT1 A;  3RKE A;  4OTY A;  3FAQ A;  1PXX A;  2QRB A;  3MDL A;  3F9P C;  3S4F A;  3ERH A;  3N8V A;  1D2V C;  3N8Z A;  5JW1 A;  3GCL A;  3Q7D A;  5COX A;  3QH0 A;  4KVL A;  3PY4 A;  5HPW A;  3QL6 A;  2R5L A;  3SXV A; 
#chains in the Genus database with same CATH topology
 1HT8 A;  3KRK A;  1PGE A;  2QQT A;  2O86 A;  1DIY A;  3NTG A;  4KVJ A;  2OYE P;  5IKV A;  4QYQ A;  3N8F A;  4RUT A;  4PNX A;  4M11 A;  3R5Q A;  5JVZ A;  2IPS A;  3N8W B;  1MYP C;  3UBA A;  5JVY A;  3Q9K A;  1D7W C;  5F1A A;  3NIU A;  6COX A;  5IKR A;  3RR3 A;  3BXI A;  3HS7 A;  1DDX A;  3GC1 A;  3OLU A;  3HS6 A;  1EQH A;  1IGZ A;  4HHR A;  1PRH A;  3ZS1 C;  2EFB A;  2NQX A;  1MHL C;  3NYH A;  3NTB A;  2Z5Z A;  4M10 A;  3V6Q A;  3MQE A;  1DNW C;  1CVU A;  2OYU P;  4RRX A;  5F19 A;  5FDQ A;  1EQG A;  4E1G A;  5IKQ A;  4MSF A;  3ZS0 C;  2E9E A;  1EBV A;  4O1Z A;  4GN6 A;  1CXP C;  3KRQ A;  1DNU C;  4QJQ A;  4DL1 C;  3ERI A;  1IGX A;  3LN0 A;  3R4X A;  4NT3 A;  3PGH A;  2EHA A;  3TZI A;  4LJJ A;  4RRY A;  3HS5 A;  4COX A;  3OLT A;  3I6N A;  3N8Y A;  3N8Y B;  3GCJ A;  5IKT A;  2OJV A;  1CX2 A;  3N8X A;  4IG5 A;  1FE2 A;  2GJM A;  4KVK A;  4N7A A;  3NAK A;  3QMO A;  3OGW A;  1D5L C;  2QPK A;  4OEK A;  3FNL A;  4KSZ A;  4OTJ A;  3GCK A;  5KIR A;  4C1M C;  1PTH A;  3R55 A;  5GH0 A;  4RRZ A;  1Q4G A;  5GLS A;  3TGY A;  4Y55 A;  2IKC A;  1U67 A;  5B72 A;  3R5O A;  5FIW C;  1HT5 A;  4PH9 A;  2PUM A;  2AYL A;  3LN1 A;  4GM7 A;  1CQE A;  4NJB A;  4RS0 A;  4Z0L A;  4FM5 A;  3QF1 A;  5FF1 A;  4HHS A;  2PT3 A;  3N8W A;  4RRW A;  3KK6 A;  3NT1 A;  3RKE A;  4OTY A;  3FAQ A;  1PXX A;  2QRB A;  3MDL A;  3F9P C;  3S4F A;  3ERH A;  3N8V A;  1D2V C;  3N8Z A;  5JW1 A;  3GCL A;  3Q7D A;  5COX A;  3QH0 A;  4KVL A;  3PY4 A;  5HPW A;  3QL6 A;  2R5L A;  3SXV A; 
#chains in the Genus database with same CATH homology
 1HT8 A;  3KRK A;  1PGE A;  2QQT A;  2O86 A;  1DIY A;  3NTG A;  4KVJ A;  2OYE P;  5IKV A;  4QYQ A;  3N8F A;  4RUT A;  4PNX A;  4M11 A;  3R5Q A;  5JVZ A;  2IPS A;  3N8W B;  1MYP C;  3UBA A;  5JVY A;  3Q9K A;  1D7W C;  5F1A A;  3NIU A;  6COX A;  5IKR A;  3RR3 A;  3BXI A;  3HS7 A;  1DDX A;  3GC1 A;  3OLU A;  3HS6 A;  1EQH A;  1IGZ A;  4HHR A;  1PRH A;  3ZS1 C;  2EFB A;  2NQX A;  1MHL C;  3NYH A;  3NTB A;  2Z5Z A;  4M10 A;  3V6Q A;  3MQE A;  1DNW C;  1CVU A;  2OYU P;  4RRX A;  5F19 A;  5FDQ A;  1EQG A;  4E1G A;  5IKQ A;  4MSF A;  3ZS0 C;  2E9E A;  1EBV A;  4O1Z A;  4GN6 A;  1CXP C;  3KRQ A;  1DNU C;  4QJQ A;  4DL1 C;  3ERI A;  1IGX A;  3LN0 A;  3R4X A;  4NT3 A;  3PGH A;  2EHA A;  3TZI A;  4LJJ A;  4RRY A;  3HS5 A;  4COX A;  3OLT A;  3I6N A;  3N8Y A;  3N8Y B;  3GCJ A;  5IKT A;  2OJV A;  1CX2 A;  3N8X A;  4IG5 A;  1FE2 A;  2GJM A;  4KVK A;  4N7A A;  3NAK A;  3QMO A;  3OGW A;  1D5L C;  2QPK A;  4OEK A;  3FNL A;  4KSZ A;  4OTJ A;  3GCK A;  5KIR A;  4C1M C;  1PTH A;  3R55 A;  5GH0 A;  4RRZ A;  1Q4G A;  5GLS A;  3TGY A;  4Y55 A;  2IKC A;  1U67 A;  5B72 A;  3R5O A;  5FIW C;  1HT5 A;  4PH9 A;  2PUM A;  2AYL A;  3LN1 A;  4GM7 A;  1CQE A;  4NJB A;  4RS0 A;  4Z0L A;  4FM5 A;  3QF1 A;  5FF1 A;  4HHS A;  2PT3 A;  3N8W A;  4RRW A;  3KK6 A;  3NT1 A;  3RKE A;  4OTY A;  3FAQ A;  1PXX A;  2QRB A;  3MDL A;  3F9P C;  3S4F A;  3ERH A;  3N8V A;  1D2V C;  3N8Z A;  5JW1 A;  3GCL A;  3Q7D A;  5COX A;  3QH0 A;  4KVL A;  3PY4 A;  5HPW A;  3QL6 A;  2R5L A;  3SXV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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