1D7WC

Crystal structure of human myeloperoxidase isoform c complexed with cyanide and bromide at ph 4.0
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
466
structure length
465
Chain Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords MYELOPEROXIDASE
total genus 145
structure length 465
sequence length 466
chains with identical sequence D
ec nomenclature ec 1.11.2.2: Myeloperoxidase.
pdb deposition date 1999-10-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 1d7wC00
4KVKA 3NTBA 3N8WA 3NAKA 3KK6A 3HS5A 2OJVA 4OTJA 3FAQA 4RS0A 2QQTA 4OEKA 1FE2A 1D2VC 1PRHA 1PXXA 3ERHA 5B72A 5IKQA 4O1ZA 1EQHA 5F19A 2AYLA 4HHSA 4C1MC 4E1GA 6COXA 1MYPC 1DIYA 3LN0A 5IKVA 3GC1A 3TZIA 5JW1A 4RRXA 4QYQA 4M11A 1CQEA 1PGEA 4NJBA 3NYHA 1DNUC 4M10A 4KSZA 1EBVA 2PUMA 3UBAA 4COXA 2O86A 2PT3A 3QMOA 4NT3A 2GJMA 4IG5A 1IGXA 4KVLA 5GH0A 5IKRA 3SXVA 4RRZA 3NTGA 5F1AA 1CXPC 3ZS0C 2E9EA 4PNXA 3N8FA 4RRYA 3I6NA 2EFBA 3F9PC 3Q9KA 1D5LC 1Q4GA 1PTHA 2IPSA 2R5LA 4Y55A 5FDQA 2QPKA 3KRQA 3Q7DA 3HS7A 3GCKA 3QF1A 2QRBA 4GM7A 4RUTA 3GCLA 4GN6A 4OTYA 1HT5A 3QL6A 3R5QA 5IKTA 2EHAA 5JVZA 2OYUP 3R4XA 3NT1A 3KRKA 3V6QA 4HHRA 1EQGA 4KVJA 1CVUA 1CX2A 3HS6A 2IKCA 4FM5A 5KIRA 5FIWC 4PH9A 1IGZA 4DL1C 1DNWC 3OLUA 5HPWA 4N7AA 2NQXA 1DDXA 3TGYA 3OGWA 3GCJA 3N8XA 3NIUA 2OYEP 3N8YA 4Z0LA 3ZS1C 4RRWA 3R5OA 1MHLC 5COXA 4MSFA 3MQEA 3R55A 5JVYA 3FNLA 4LJJA 3N8WB 3OLTA 5FF1A 3N8ZA 3RKEA 3PY4A 1U67A 3ERIA 1D7WC 3N8YB 3QH0A 3RR3A 3LN1A 4QJQA 3PGHA 2Z5ZA 3BXIA 1HT8A 5GLSA 3S4FA 3N8VA 3MDLA
chains in the Genus database with same CATH superfamily
4KVKA 3NTBA 3N8WA 3NAKA 3KK6A 3HS5A 2OJVA 4OTJA 3FAQA 4RS0A 2QQTA 4OEKA 1FE2A 1D2VC 1PRHA 1PXXA 3ERHA 5B72A 5IKQA 4O1ZA 1EQHA 5F19A 2AYLA 4HHSA 4C1MC 4E1GA 6COXA 1MYPC 1DIYA 3LN0A 5IKVA 3GC1A 3TZIA 5JW1A 4RRXA 4QYQA 4M11A 1CQEA 1PGEA 4NJBA 3NYHA 1DNUC 4M10A 4KSZA 1EBVA 2PUMA 3UBAA 4COXA 2O86A 2PT3A 3QMOA 4NT3A 2GJMA 4IG5A 1IGXA 4KVLA 5GH0A 5IKRA 3SXVA 4RRZA 3NTGA 5F1AA 1CXPC 3ZS0C 2E9EA 4PNXA 3N8FA 4RRYA 3I6NA 2EFBA 3F9PC 3Q9KA 1D5LC 1Q4GA 1PTHA 2IPSA 2R5LA 4Y55A 5FDQA 2QPKA 3KRQA 3Q7DA 3HS7A 3GCKA 3QF1A 2QRBA 4GM7A 4RUTA 3GCLA 4GN6A 4OTYA 1HT5A 3QL6A 3R5QA 5IKTA 2EHAA 5JVZA 2OYUP 3R4XA 3NT1A 3KRKA 3V6QA 4HHRA 1EQGA 4KVJA 1CVUA 1CX2A 3HS6A 2IKCA 4FM5A 5KIRA 5FIWC 4PH9A 1IGZA 4DL1C 1DNWC 3OLUA 5HPWA 4N7AA 2NQXA 1DDXA 3TGYA 3OGWA 3GCJA 3N8XA 3NIUA 2OYEP 3N8YA 4Z0LA 3ZS1C 4RRWA 3R5OA 1MHLC 5COXA 4MSFA 3MQEA 3R55A 5JVYA 3FNLA 4LJJA 3N8WB 3OLTA 5FF1A 3N8ZA 3RKEA 3PY4A 1U67A 3ERIA 1D7WC 3N8YB 3QH0A 3RR3A 3LN1A 4QJQA 3PGHA 2Z5ZA 3BXIA 1HT8A 5GLSA 3S4FA 3N8VA 3MDLA
chains in the Genus database with same CATH topology
4KVKA 3NTBA 3N8WA 3NAKA 3KK6A 3HS5A 2OJVA 4OTJA 3FAQA 4RS0A 2QQTA 4OEKA 1FE2A 1D2VC 1PRHA 1PXXA 3ERHA 5B72A 5IKQA 4O1ZA 1EQHA 5F19A 2AYLA 4HHSA 4C1MC 4E1GA 6COXA 1MYPC 1DIYA 3LN0A 5IKVA 3GC1A 3TZIA 5JW1A 4RRXA 4QYQA 4M11A 1CQEA 1PGEA 4NJBA 3NYHA 1DNUC 4M10A 4KSZA 1EBVA 2PUMA 3UBAA 4COXA 2O86A 2PT3A 3QMOA 4NT3A 2GJMA 4IG5A 1IGXA 4KVLA 5GH0A 5IKRA 3SXVA 4RRZA 3NTGA 5F1AA 1CXPC 3ZS0C 2E9EA 4PNXA 3N8FA 4RRYA 3I6NA 2EFBA 3F9PC 3Q9KA 1D5LC 1Q4GA 1PTHA 2IPSA 2R5LA 4Y55A 5FDQA 2QPKA 3KRQA 3Q7DA 3HS7A 3GCKA 3QF1A 2QRBA 4GM7A 4RUTA 3GCLA 4GN6A 4OTYA 1HT5A 3QL6A 3R5QA 5IKTA 2EHAA 5JVZA 2OYUP 3R4XA 3NT1A 3KRKA 3V6QA 4HHRA 1EQGA 4KVJA 1CVUA 1CX2A 3HS6A 2IKCA 4FM5A 5KIRA 5FIWC 4PH9A 1IGZA 4DL1C 1DNWC 3OLUA 5HPWA 4N7AA 2NQXA 1DDXA 3TGYA 3OGWA 3GCJA 3N8XA 3NIUA 2OYEP 3N8YA 4Z0LA 3ZS1C 4RRWA 3R5OA 1MHLC 5COXA 4MSFA 3MQEA 3R55A 5JVYA 3FNLA 4LJJA 3N8WB 3OLTA 5FF1A 3N8ZA 3RKEA 3PY4A 1U67A 3ERIA 1D7WC 3N8YB 3QH0A 3RR3A 3LN1A 4QJQA 3PGHA 2Z5ZA 3BXIA 1HT8A 5GLSA 3S4FA 3N8VA 3MDLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KVK A;  3NTB A;  3N8W A;  3NAK A;  3KK6 A;  3HS5 A;  2OJV A;  4OTJ A;  3FAQ A;  4RS0 A;  2QQT A;  4OEK A;  1FE2 A;  1D2V C;  1PRH A;  1PXX A;  3ERH A;  5B72 A;  5IKQ A;  4O1Z A;  1EQH A;  5F19 A;  2AYL A;  4HHS A;  4C1M C;  4E1G A;  6COX A;  1MYP C;  1DIY A;  3LN0 A;  5IKV A;  3GC1 A;  3TZI A;  5JW1 A;  4RRX A;  4QYQ A;  4M11 A;  1CQE A;  1PGE A;  4NJB A;  3NYH A;  1DNU C;  4M10 A;  4KSZ A;  1EBV A;  2PUM A;  3UBA A;  4COX A;  2O86 A;  2PT3 A;  3QMO A;  4NT3 A;  2GJM A;  4IG5 A;  1IGX A;  4KVL A;  5GH0 A;  5IKR A;  3SXV A;  4RRZ A;  3NTG A;  5F1A A;  1CXP C;  3ZS0 C;  2E9E A;  4PNX A;  3N8F A;  4RRY A;  3I6N A;  2EFB A;  3F9P C;  3Q9K A;  1D5L C;  1Q4G A;  1PTH A;  2IPS A;  2R5L A;  4Y55 A;  5FDQ A;  2QPK A;  3KRQ A;  3Q7D A;  3HS7 A;  3GCK A;  3QF1 A;  2QRB A;  4GM7 A;  4RUT A;  3GCL A;  4GN6 A;  4OTY A;  1HT5 A;  3QL6 A;  3R5Q A;  5IKT A;  2EHA A;  5JVZ A;  2OYU P;  3R4X A;  3NT1 A;  3KRK A;  3V6Q A;  4HHR A;  1EQG A;  4KVJ A;  1CVU A;  1CX2 A;  3HS6 A;  2IKC A;  4FM5 A;  5KIR A;  5FIW C;  4PH9 A;  1IGZ A;  4DL1 C;  1DNW C;  3OLU A;  5HPW A;  4N7A A;  2NQX A;  1DDX A;  3TGY A;  3OGW A;  3GCJ A;  3N8X A;  3NIU A;  2OYE P;  3N8Y A;  4Z0L A;  3ZS1 C;  4RRW A;  3R5O A;  1MHL C;  5COX A;  4MSF A;  3MQE A;  3R55 A;  5JVY A;  3FNL A;  4LJJ A;  3N8W B;  3OLT A;  5FF1 A;  3N8Z A;  3RKE A;  3PY4 A;  1U67 A;  3ERI A;  1D7W C;  3N8Y B;  3QH0 A;  3RR3 A;  3LN1 A;  4QJQ A;  3PGH A;  2Z5Z A;  3BXI A;  1HT8 A;  5GLS A;  3S4F A;  3N8V A;  3MDL A; 
#chains in the Genus database with same CATH topology
 4KVK A;  3NTB A;  3N8W A;  3NAK A;  3KK6 A;  3HS5 A;  2OJV A;  4OTJ A;  3FAQ A;  4RS0 A;  2QQT A;  4OEK A;  1FE2 A;  1D2V C;  1PRH A;  1PXX A;  3ERH A;  5B72 A;  5IKQ A;  4O1Z A;  1EQH A;  5F19 A;  2AYL A;  4HHS A;  4C1M C;  4E1G A;  6COX A;  1MYP C;  1DIY A;  3LN0 A;  5IKV A;  3GC1 A;  3TZI A;  5JW1 A;  4RRX A;  4QYQ A;  4M11 A;  1CQE A;  1PGE A;  4NJB A;  3NYH A;  1DNU C;  4M10 A;  4KSZ A;  1EBV A;  2PUM A;  3UBA A;  4COX A;  2O86 A;  2PT3 A;  3QMO A;  4NT3 A;  2GJM A;  4IG5 A;  1IGX A;  4KVL A;  5GH0 A;  5IKR A;  3SXV A;  4RRZ A;  3NTG A;  5F1A A;  1CXP C;  3ZS0 C;  2E9E A;  4PNX A;  3N8F A;  4RRY A;  3I6N A;  2EFB A;  3F9P C;  3Q9K A;  1D5L C;  1Q4G A;  1PTH A;  2IPS A;  2R5L A;  4Y55 A;  5FDQ A;  2QPK A;  3KRQ A;  3Q7D A;  3HS7 A;  3GCK A;  3QF1 A;  2QRB A;  4GM7 A;  4RUT A;  3GCL A;  4GN6 A;  4OTY A;  1HT5 A;  3QL6 A;  3R5Q A;  5IKT A;  2EHA A;  5JVZ A;  2OYU P;  3R4X A;  3NT1 A;  3KRK A;  3V6Q A;  4HHR A;  1EQG A;  4KVJ A;  1CVU A;  1CX2 A;  3HS6 A;  2IKC A;  4FM5 A;  5KIR A;  5FIW C;  4PH9 A;  1IGZ A;  4DL1 C;  1DNW C;  3OLU A;  5HPW A;  4N7A A;  2NQX A;  1DDX A;  3TGY A;  3OGW A;  3GCJ A;  3N8X A;  3NIU A;  2OYE P;  3N8Y A;  4Z0L A;  3ZS1 C;  4RRW A;  3R5O A;  1MHL C;  5COX A;  4MSF A;  3MQE A;  3R55 A;  5JVY A;  3FNL A;  4LJJ A;  3N8W B;  3OLT A;  5FF1 A;  3N8Z A;  3RKE A;  3PY4 A;  1U67 A;  3ERI A;  1D7W C;  3N8Y B;  3QH0 A;  3RR3 A;  3LN1 A;  4QJQ A;  3PGH A;  2Z5Z A;  3BXI A;  1HT8 A;  5GLS A;  3S4F A;  3N8V A;  3MDL A; 
#chains in the Genus database with same CATH homology
 4KVK A;  3NTB A;  3N8W A;  3NAK A;  3KK6 A;  3HS5 A;  2OJV A;  4OTJ A;  3FAQ A;  4RS0 A;  2QQT A;  4OEK A;  1FE2 A;  1D2V C;  1PRH A;  1PXX A;  3ERH A;  5B72 A;  5IKQ A;  4O1Z A;  1EQH A;  5F19 A;  2AYL A;  4HHS A;  4C1M C;  4E1G A;  6COX A;  1MYP C;  1DIY A;  3LN0 A;  5IKV A;  3GC1 A;  3TZI A;  5JW1 A;  4RRX A;  4QYQ A;  4M11 A;  1CQE A;  1PGE A;  4NJB A;  3NYH A;  1DNU C;  4M10 A;  4KSZ A;  1EBV A;  2PUM A;  3UBA A;  4COX A;  2O86 A;  2PT3 A;  3QMO A;  4NT3 A;  2GJM A;  4IG5 A;  1IGX A;  4KVL A;  5GH0 A;  5IKR A;  3SXV A;  4RRZ A;  3NTG A;  5F1A A;  1CXP C;  3ZS0 C;  2E9E A;  4PNX A;  3N8F A;  4RRY A;  3I6N A;  2EFB A;  3F9P C;  3Q9K A;  1D5L C;  1Q4G A;  1PTH A;  2IPS A;  2R5L A;  4Y55 A;  5FDQ A;  2QPK A;  3KRQ A;  3Q7D A;  3HS7 A;  3GCK A;  3QF1 A;  2QRB A;  4GM7 A;  4RUT A;  3GCL A;  4GN6 A;  4OTY A;  1HT5 A;  3QL6 A;  3R5Q A;  5IKT A;  2EHA A;  5JVZ A;  2OYU P;  3R4X A;  3NT1 A;  3KRK A;  3V6Q A;  4HHR A;  1EQG A;  4KVJ A;  1CVU A;  1CX2 A;  3HS6 A;  2IKC A;  4FM5 A;  5KIR A;  5FIW C;  4PH9 A;  1IGZ A;  4DL1 C;  1DNW C;  3OLU A;  5HPW A;  4N7A A;  2NQX A;  1DDX A;  3TGY A;  3OGW A;  3GCJ A;  3N8X A;  3NIU A;  2OYE P;  3N8Y A;  4Z0L A;  3ZS1 C;  4RRW A;  3R5O A;  1MHL C;  5COX A;  4MSF A;  3MQE A;  3R55 A;  5JVY A;  3FNL A;  4LJJ A;  3N8W B;  3OLT A;  5FF1 A;  3N8Z A;  3RKE A;  3PY4 A;  1U67 A;  3ERI A;  1D7W C;  3N8Y B;  3QH0 A;  3RR3 A;  3LN1 A;  4QJQ A;  3PGH A;  2Z5Z A;  3BXI A;  1HT8 A;  5GLS A;  3S4F A;  3N8V A;  3MDL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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