1DNUC

Structural analyses of human myeloperoxidase-thiocyanate complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
466
structure length
465
Chain Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords MYELOPEROXIDASE
total genus 143
structure length 465
sequence length 466
chains with identical sequence D
ec nomenclature ec 1.11.2.2: Myeloperoxidase.
pdb deposition date 1999-12-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 1dnuC00
3N8WB 4O1ZA 3UBAA 2QRBA 3ERHA 3TZIA 1HT5A 4OEKA 3SXVA 1D7WC 3I6NA 4OTJA 3N8YB 1CXPC 2QQTA 3Q7DA 4NT3A 5JVYA 4M11A 1EQGA 3KK6A 4RS0A 3OGWA 3MQEA 5HPWA 3QF1A 4RRXA 3NAKA 4IG5A 1Q4GA 3FNLA 3GCJA 3PGHA 4DL1C 4RRZA 4GN6A 5FDQA 4KVKA 1EQHA 4RRYA 5IKQA 2PUMA 4E1GA 1PTHA 4PH9A 3N8VA 3NT1A 2IPSA 3BXIA 3NYHA 2EFBA 3LN1A 3NIUA 4PNXA 4RRWA 4GM7A 5F1AA 5JVZA 3R4XA 2IKCA 2OYUP 5IKVA 4KSZA 3PY4A 3QH0A 2O86A 1PXXA 3F9PC 4COXA 4KVJA 3S4FA 1HT8A 4HHSA 1D5LC 3Q9KA 3KRQA 3GCLA 3OLUA 3NTGA 3ERIA 3FAQA 5FF1A 3N8XA 6COXA 2Z5ZA 5F19A 3HS6A 2R5LA 3ZS1C 4N7AA 1CQEA 3N8ZA 4Z0LA 4QYQA 5GH0A 1PRHA 2QPKA 1FE2A 1MYPC 2OJVA 5IKRA 4Y55A 3RR3A 3KRKA 3LN0A 4HHRA 1DNWC 2GJMA 2PT3A 1DIYA 4RUTA 3R55A 3N8WA 4C1MC 3R5OA 3HS7A 1CVUA 2OYEP 4OTYA 4LJJA 1CX2A 1MHLC 3OLTA 1U67A 4QJQA 1DDXA 4FM5A 3N8YA 2E9EA 3V6QA 3N8FA 3QMOA 3NTBA 5B72A 4MSFA 2AYLA 3QL6A 1IGZA 5GLSA 5IKTA 1DNUC 3HS5A 4KVLA 1D2VC 5COXA 2EHAA 2NQXA 3ZS0C 5FIWC 1PGEA 3GCKA 4M10A 1EBVA 3GC1A 5KIRA 3TGYA 3R5QA 3RKEA 5JW1A 4NJBA 1IGXA 3MDLA
chains in the Genus database with same CATH superfamily
3N8WB 4O1ZA 3UBAA 2QRBA 3ERHA 3TZIA 1HT5A 4OEKA 3SXVA 1D7WC 3I6NA 4OTJA 3N8YB 1CXPC 2QQTA 3Q7DA 4NT3A 5JVYA 4M11A 1EQGA 3KK6A 4RS0A 3OGWA 3MQEA 5HPWA 3QF1A 4RRXA 3NAKA 4IG5A 1Q4GA 3FNLA 3GCJA 3PGHA 4DL1C 4RRZA 4GN6A 5FDQA 4KVKA 1EQHA 4RRYA 5IKQA 2PUMA 4E1GA 1PTHA 4PH9A 3N8VA 3NT1A 2IPSA 3BXIA 3NYHA 2EFBA 3LN1A 3NIUA 4PNXA 4RRWA 4GM7A 5F1AA 5JVZA 3R4XA 2IKCA 2OYUP 5IKVA 4KSZA 3PY4A 3QH0A 2O86A 1PXXA 3F9PC 4COXA 4KVJA 3S4FA 1HT8A 4HHSA 1D5LC 3Q9KA 3KRQA 3GCLA 3OLUA 3NTGA 3ERIA 3FAQA 5FF1A 3N8XA 6COXA 2Z5ZA 5F19A 3HS6A 2R5LA 3ZS1C 4N7AA 1CQEA 3N8ZA 4Z0LA 4QYQA 5GH0A 1PRHA 2QPKA 1FE2A 1MYPC 2OJVA 5IKRA 4Y55A 3RR3A 3KRKA 3LN0A 4HHRA 1DNWC 2GJMA 2PT3A 1DIYA 4RUTA 3R55A 3N8WA 4C1MC 3R5OA 3HS7A 1CVUA 2OYEP 4OTYA 4LJJA 1CX2A 1MHLC 3OLTA 1U67A 4QJQA 1DDXA 4FM5A 3N8YA 2E9EA 3V6QA 3N8FA 3QMOA 3NTBA 5B72A 4MSFA 2AYLA 3QL6A 1IGZA 5GLSA 5IKTA 1DNUC 3HS5A 4KVLA 1D2VC 5COXA 2EHAA 2NQXA 3ZS0C 5FIWC 1PGEA 3GCKA 4M10A 1EBVA 3GC1A 5KIRA 3TGYA 3R5QA 3RKEA 5JW1A 4NJBA 1IGXA 3MDLA
chains in the Genus database with same CATH topology
3N8WB 4O1ZA 3UBAA 2QRBA 3ERHA 3TZIA 1HT5A 4OEKA 3SXVA 1D7WC 3I6NA 4OTJA 3N8YB 1CXPC 2QQTA 3Q7DA 4NT3A 5JVYA 4M11A 1EQGA 3KK6A 4RS0A 3OGWA 3MQEA 5HPWA 3QF1A 4RRXA 3NAKA 4IG5A 1Q4GA 3FNLA 3GCJA 3PGHA 4DL1C 4RRZA 4GN6A 5FDQA 4KVKA 1EQHA 4RRYA 5IKQA 2PUMA 4E1GA 1PTHA 4PH9A 3N8VA 3NT1A 2IPSA 3BXIA 3NYHA 2EFBA 3LN1A 3NIUA 4PNXA 4RRWA 4GM7A 5F1AA 5JVZA 3R4XA 2IKCA 2OYUP 5IKVA 4KSZA 3PY4A 3QH0A 2O86A 1PXXA 3F9PC 4COXA 4KVJA 3S4FA 1HT8A 4HHSA 1D5LC 3Q9KA 3KRQA 3GCLA 3OLUA 3NTGA 3ERIA 3FAQA 5FF1A 3N8XA 6COXA 2Z5ZA 5F19A 3HS6A 2R5LA 3ZS1C 4N7AA 1CQEA 3N8ZA 4Z0LA 4QYQA 5GH0A 1PRHA 2QPKA 1FE2A 1MYPC 2OJVA 5IKRA 4Y55A 3RR3A 3KRKA 3LN0A 4HHRA 1DNWC 2GJMA 2PT3A 1DIYA 4RUTA 3R55A 3N8WA 4C1MC 3R5OA 3HS7A 1CVUA 2OYEP 4OTYA 4LJJA 1CX2A 1MHLC 3OLTA 1U67A 4QJQA 1DDXA 4FM5A 3N8YA 2E9EA 3V6QA 3N8FA 3QMOA 3NTBA 5B72A 4MSFA 2AYLA 3QL6A 1IGZA 5GLSA 5IKTA 1DNUC 3HS5A 4KVLA 1D2VC 5COXA 2EHAA 2NQXA 3ZS0C 5FIWC 1PGEA 3GCKA 4M10A 1EBVA 3GC1A 5KIRA 3TGYA 3R5QA 3RKEA 5JW1A 4NJBA 1IGXA 3MDLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N8W B;  4O1Z A;  3UBA A;  2QRB A;  3ERH A;  3TZI A;  1HT5 A;  4OEK A;  3SXV A;  1D7W C;  3I6N A;  4OTJ A;  3N8Y B;  1CXP C;  2QQT A;  3Q7D A;  4NT3 A;  5JVY A;  4M11 A;  1EQG A;  3KK6 A;  4RS0 A;  3OGW A;  3MQE A;  5HPW A;  3QF1 A;  4RRX A;  3NAK A;  4IG5 A;  1Q4G A;  3FNL A;  3GCJ A;  3PGH A;  4DL1 C;  4RRZ A;  4GN6 A;  5FDQ A;  4KVK A;  1EQH A;  4RRY A;  5IKQ A;  2PUM A;  4E1G A;  1PTH A;  4PH9 A;  3N8V A;  3NT1 A;  2IPS A;  3BXI A;  3NYH A;  2EFB A;  3LN1 A;  3NIU A;  4PNX A;  4RRW A;  4GM7 A;  5F1A A;  5JVZ A;  3R4X A;  2IKC A;  2OYU P;  5IKV A;  4KSZ A;  3PY4 A;  3QH0 A;  2O86 A;  1PXX A;  3F9P C;  4COX A;  4KVJ A;  3S4F A;  1HT8 A;  4HHS A;  1D5L C;  3Q9K A;  3KRQ A;  3GCL A;  3OLU A;  3NTG A;  3ERI A;  3FAQ A;  5FF1 A;  3N8X A;  6COX A;  2Z5Z A;  5F19 A;  3HS6 A;  2R5L A;  3ZS1 C;  4N7A A;  1CQE A;  3N8Z A;  4Z0L A;  4QYQ A;  5GH0 A;  1PRH A;  2QPK A;  1FE2 A;  1MYP C;  2OJV A;  5IKR A;  4Y55 A;  3RR3 A;  3KRK A;  3LN0 A;  4HHR A;  1DNW C;  2GJM A;  2PT3 A;  1DIY A;  4RUT A;  3R55 A;  3N8W A;  4C1M C;  3R5O A;  3HS7 A;  1CVU A;  2OYE P;  4OTY A;  4LJJ A;  1CX2 A;  1MHL C;  3OLT A;  1U67 A;  4QJQ A;  1DDX A;  4FM5 A;  3N8Y A;  2E9E A;  3V6Q A;  3N8F A;  3QMO A;  3NTB A;  5B72 A;  4MSF A;  2AYL A;  3QL6 A;  1IGZ A;  5GLS A;  5IKT A;  1DNU C;  3HS5 A;  4KVL A;  1D2V C;  5COX A;  2EHA A;  2NQX A;  3ZS0 C;  5FIW C;  1PGE A;  3GCK A;  4M10 A;  1EBV A;  3GC1 A;  5KIR A;  3TGY A;  3R5Q A;  3RKE A;  5JW1 A;  4NJB A;  1IGX A;  3MDL A; 
#chains in the Genus database with same CATH topology
 3N8W B;  4O1Z A;  3UBA A;  2QRB A;  3ERH A;  3TZI A;  1HT5 A;  4OEK A;  3SXV A;  1D7W C;  3I6N A;  4OTJ A;  3N8Y B;  1CXP C;  2QQT A;  3Q7D A;  4NT3 A;  5JVY A;  4M11 A;  1EQG A;  3KK6 A;  4RS0 A;  3OGW A;  3MQE A;  5HPW A;  3QF1 A;  4RRX A;  3NAK A;  4IG5 A;  1Q4G A;  3FNL A;  3GCJ A;  3PGH A;  4DL1 C;  4RRZ A;  4GN6 A;  5FDQ A;  4KVK A;  1EQH A;  4RRY A;  5IKQ A;  2PUM A;  4E1G A;  1PTH A;  4PH9 A;  3N8V A;  3NT1 A;  2IPS A;  3BXI A;  3NYH A;  2EFB A;  3LN1 A;  3NIU A;  4PNX A;  4RRW A;  4GM7 A;  5F1A A;  5JVZ A;  3R4X A;  2IKC A;  2OYU P;  5IKV A;  4KSZ A;  3PY4 A;  3QH0 A;  2O86 A;  1PXX A;  3F9P C;  4COX A;  4KVJ A;  3S4F A;  1HT8 A;  4HHS A;  1D5L C;  3Q9K A;  3KRQ A;  3GCL A;  3OLU A;  3NTG A;  3ERI A;  3FAQ A;  5FF1 A;  3N8X A;  6COX A;  2Z5Z A;  5F19 A;  3HS6 A;  2R5L A;  3ZS1 C;  4N7A A;  1CQE A;  3N8Z A;  4Z0L A;  4QYQ A;  5GH0 A;  1PRH A;  2QPK A;  1FE2 A;  1MYP C;  2OJV A;  5IKR A;  4Y55 A;  3RR3 A;  3KRK A;  3LN0 A;  4HHR A;  1DNW C;  2GJM A;  2PT3 A;  1DIY A;  4RUT A;  3R55 A;  3N8W A;  4C1M C;  3R5O A;  3HS7 A;  1CVU A;  2OYE P;  4OTY A;  4LJJ A;  1CX2 A;  1MHL C;  3OLT A;  1U67 A;  4QJQ A;  1DDX A;  4FM5 A;  3N8Y A;  2E9E A;  3V6Q A;  3N8F A;  3QMO A;  3NTB A;  5B72 A;  4MSF A;  2AYL A;  3QL6 A;  1IGZ A;  5GLS A;  5IKT A;  1DNU C;  3HS5 A;  4KVL A;  1D2V C;  5COX A;  2EHA A;  2NQX A;  3ZS0 C;  5FIW C;  1PGE A;  3GCK A;  4M10 A;  1EBV A;  3GC1 A;  5KIR A;  3TGY A;  3R5Q A;  3RKE A;  5JW1 A;  4NJB A;  1IGX A;  3MDL A; 
#chains in the Genus database with same CATH homology
 3N8W B;  4O1Z A;  3UBA A;  2QRB A;  3ERH A;  3TZI A;  1HT5 A;  4OEK A;  3SXV A;  1D7W C;  3I6N A;  4OTJ A;  3N8Y B;  1CXP C;  2QQT A;  3Q7D A;  4NT3 A;  5JVY A;  4M11 A;  1EQG A;  3KK6 A;  4RS0 A;  3OGW A;  3MQE A;  5HPW A;  3QF1 A;  4RRX A;  3NAK A;  4IG5 A;  1Q4G A;  3FNL A;  3GCJ A;  3PGH A;  4DL1 C;  4RRZ A;  4GN6 A;  5FDQ A;  4KVK A;  1EQH A;  4RRY A;  5IKQ A;  2PUM A;  4E1G A;  1PTH A;  4PH9 A;  3N8V A;  3NT1 A;  2IPS A;  3BXI A;  3NYH A;  2EFB A;  3LN1 A;  3NIU A;  4PNX A;  4RRW A;  4GM7 A;  5F1A A;  5JVZ A;  3R4X A;  2IKC A;  2OYU P;  5IKV A;  4KSZ A;  3PY4 A;  3QH0 A;  2O86 A;  1PXX A;  3F9P C;  4COX A;  4KVJ A;  3S4F A;  1HT8 A;  4HHS A;  1D5L C;  3Q9K A;  3KRQ A;  3GCL A;  3OLU A;  3NTG A;  3ERI A;  3FAQ A;  5FF1 A;  3N8X A;  6COX A;  2Z5Z A;  5F19 A;  3HS6 A;  2R5L A;  3ZS1 C;  4N7A A;  1CQE A;  3N8Z A;  4Z0L A;  4QYQ A;  5GH0 A;  1PRH A;  2QPK A;  1FE2 A;  1MYP C;  2OJV A;  5IKR A;  4Y55 A;  3RR3 A;  3KRK A;  3LN0 A;  4HHR A;  1DNW C;  2GJM A;  2PT3 A;  1DIY A;  4RUT A;  3R55 A;  3N8W A;  4C1M C;  3R5O A;  3HS7 A;  1CVU A;  2OYE P;  4OTY A;  4LJJ A;  1CX2 A;  1MHL C;  3OLT A;  1U67 A;  4QJQ A;  1DDX A;  4FM5 A;  3N8Y A;  2E9E A;  3V6Q A;  3N8F A;  3QMO A;  3NTB A;  5B72 A;  4MSF A;  2AYL A;  3QL6 A;  1IGZ A;  5GLS A;  5IKT A;  1DNU C;  3HS5 A;  4KVL A;  1D2V C;  5COX A;  2EHA A;  2NQX A;  3ZS0 C;  5FIW C;  1PGE A;  3GCK A;  4M10 A;  1EBV A;  3GC1 A;  5KIR A;  3TGY A;  3R5Q A;  3RKE A;  5JW1 A;  4NJB A;  1IGX A;  3MDL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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