1DNWC

Human myeloperoxidase-cyanide-thiocyanate complex
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
466
structure length
465
Chain Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords MYELOPEROXIDASE
total genus 140
structure length 465
sequence length 466
chains with identical sequence D
ec nomenclature ec 1.11.2.2: Myeloperoxidase.
pdb deposition date 1999-12-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 1dnwC00
4PH9A 3NYHA 4COXA 3R5QA 3HS5A 1CQEA 1Q4GA 4RRZA 2OYEP 4Z0LA 3R4XA 4KVJA 6COXA 3ZS0C 2QPKA 1DIYA 1HT8A 2GJMA 3SXVA 3R55A 4OTYA 4QJQA 3OLTA 4QYQA 3GCKA 4KSZA 3TGYA 3NIUA 3RKEA 4M10A 3TZIA 3N8FA 3KK6A 3ERHA 3NTBA 1EQGA 4RRYA 3N8YA 4O1ZA 4GM7A 2Z5ZA 3R5OA 3KRQA 1PXXA 5IKRA 1PGEA 1HT5A 5FDQA 1U67A 4Y55A 3ERIA 3MDLA 4KVLA 2NQXA 5IKVA 2OJVA 1CVUA 4N7AA 3V6QA 3Q7DA 2PT3A 1MHLC 4MSFA 3HS6A 5IKQA 3RR3A 5GLSA 3LN0A 3FAQA 3ZS1C 1D7WC 5IKTA 2EFBA 4PNXA 3GC1A 1EQHA 1MYPC 2R5LA 3N8YB 3N8ZA 3Q9KA 5KIRA 3LN1A 3QF1A 2E9EA 3UBAA 3OGWA 4HHSA 5HPWA 1D2VC 1IGXA 4RRXA 5GH0A 4KVKA 3N8WA 3QL6A 3NT1A 3QMOA 5JVYA 1D5LC 1EBVA 5JW1A 3I6NA 5B72A 1PTHA 3HS7A 4NJBA 3KRKA 4OEKA 3QH0A 2IPSA 4M11A 3N8XA 2IKCA 1CXPC 4DL1C 3PY4A 1CX2A 4OTJA 4RS0A 4FM5A 5JVZA 2QQTA 2O86A 3BXIA 4IG5A 1IGZA 5COXA 3GCJA 4RRWA 2EHAA 3FNLA 1FE2A 1DNUC 5FF1A 3N8VA 3NAKA 1PRHA 4E1GA 4LJJA 4GN6A 5F1AA 3GCLA 3N8WB 1DDXA 2PUMA 2OYUP 1DNWC 2QRBA 3OLUA 3MQEA 4NT3A 3NTGA 3F9PC 4RUTA 4HHRA 2AYLA 5FIWC 3PGHA 4C1MC 5F19A 3S4FA
chains in the Genus database with same CATH superfamily
4PH9A 3NYHA 4COXA 3R5QA 3HS5A 1CQEA 1Q4GA 4RRZA 2OYEP 4Z0LA 3R4XA 4KVJA 6COXA 3ZS0C 2QPKA 1DIYA 1HT8A 2GJMA 3SXVA 3R55A 4OTYA 4QJQA 3OLTA 4QYQA 3GCKA 4KSZA 3TGYA 3NIUA 3RKEA 4M10A 3TZIA 3N8FA 3KK6A 3ERHA 3NTBA 1EQGA 4RRYA 3N8YA 4O1ZA 4GM7A 2Z5ZA 3R5OA 3KRQA 1PXXA 5IKRA 1PGEA 1HT5A 5FDQA 1U67A 4Y55A 3ERIA 3MDLA 4KVLA 2NQXA 5IKVA 2OJVA 1CVUA 4N7AA 3V6QA 3Q7DA 2PT3A 1MHLC 4MSFA 3HS6A 5IKQA 3RR3A 5GLSA 3LN0A 3FAQA 3ZS1C 1D7WC 5IKTA 2EFBA 4PNXA 3GC1A 1EQHA 1MYPC 2R5LA 3N8YB 3N8ZA 3Q9KA 5KIRA 3LN1A 3QF1A 2E9EA 3UBAA 3OGWA 4HHSA 5HPWA 1D2VC 1IGXA 4RRXA 5GH0A 4KVKA 3N8WA 3QL6A 3NT1A 3QMOA 5JVYA 1D5LC 1EBVA 5JW1A 3I6NA 5B72A 1PTHA 3HS7A 4NJBA 3KRKA 4OEKA 3QH0A 2IPSA 4M11A 3N8XA 2IKCA 1CXPC 4DL1C 3PY4A 1CX2A 4OTJA 4RS0A 4FM5A 5JVZA 2QQTA 2O86A 3BXIA 4IG5A 1IGZA 5COXA 3GCJA 4RRWA 2EHAA 3FNLA 1FE2A 1DNUC 5FF1A 3N8VA 3NAKA 1PRHA 4E1GA 4LJJA 4GN6A 5F1AA 3GCLA 3N8WB 1DDXA 2PUMA 2OYUP 1DNWC 2QRBA 3OLUA 3MQEA 4NT3A 3NTGA 3F9PC 4RUTA 4HHRA 2AYLA 5FIWC 3PGHA 4C1MC 5F19A 3S4FA
chains in the Genus database with same CATH topology
4PH9A 3NYHA 4COXA 3R5QA 3HS5A 1CQEA 1Q4GA 4RRZA 2OYEP 4Z0LA 3R4XA 4KVJA 6COXA 3ZS0C 2QPKA 1DIYA 1HT8A 2GJMA 3SXVA 3R55A 4OTYA 4QJQA 3OLTA 4QYQA 3GCKA 4KSZA 3TGYA 3NIUA 3RKEA 4M10A 3TZIA 3N8FA 3KK6A 3ERHA 3NTBA 1EQGA 4RRYA 3N8YA 4O1ZA 4GM7A 2Z5ZA 3R5OA 3KRQA 1PXXA 5IKRA 1PGEA 1HT5A 5FDQA 1U67A 4Y55A 3ERIA 3MDLA 4KVLA 2NQXA 5IKVA 2OJVA 1CVUA 4N7AA 3V6QA 3Q7DA 2PT3A 1MHLC 4MSFA 3HS6A 5IKQA 3RR3A 5GLSA 3LN0A 3FAQA 3ZS1C 1D7WC 5IKTA 2EFBA 4PNXA 3GC1A 1EQHA 1MYPC 2R5LA 3N8YB 3N8ZA 3Q9KA 5KIRA 3LN1A 3QF1A 2E9EA 3UBAA 3OGWA 4HHSA 5HPWA 1D2VC 1IGXA 4RRXA 5GH0A 4KVKA 3N8WA 3QL6A 3NT1A 3QMOA 5JVYA 1D5LC 1EBVA 5JW1A 3I6NA 5B72A 1PTHA 3HS7A 4NJBA 3KRKA 4OEKA 3QH0A 2IPSA 4M11A 3N8XA 2IKCA 1CXPC 4DL1C 3PY4A 1CX2A 4OTJA 4RS0A 4FM5A 5JVZA 2QQTA 2O86A 3BXIA 4IG5A 1IGZA 5COXA 3GCJA 4RRWA 2EHAA 3FNLA 1FE2A 1DNUC 5FF1A 3N8VA 3NAKA 1PRHA 4E1GA 4LJJA 4GN6A 5F1AA 3GCLA 3N8WB 1DDXA 2PUMA 2OYUP 1DNWC 2QRBA 3OLUA 3MQEA 4NT3A 3NTGA 3F9PC 4RUTA 4HHRA 2AYLA 5FIWC 3PGHA 4C1MC 5F19A 3S4FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PH9 A;  3NYH A;  4COX A;  3R5Q A;  3HS5 A;  1CQE A;  1Q4G A;  4RRZ A;  2OYE P;  4Z0L A;  3R4X A;  4KVJ A;  6COX A;  3ZS0 C;  2QPK A;  1DIY A;  1HT8 A;  2GJM A;  3SXV A;  3R55 A;  4OTY A;  4QJQ A;  3OLT A;  4QYQ A;  3GCK A;  4KSZ A;  3TGY A;  3NIU A;  3RKE A;  4M10 A;  3TZI A;  3N8F A;  3KK6 A;  3ERH A;  3NTB A;  1EQG A;  4RRY A;  3N8Y A;  4O1Z A;  4GM7 A;  2Z5Z A;  3R5O A;  3KRQ A;  1PXX A;  5IKR A;  1PGE A;  1HT5 A;  5FDQ A;  1U67 A;  4Y55 A;  3ERI A;  3MDL A;  4KVL A;  2NQX A;  5IKV A;  2OJV A;  1CVU A;  4N7A A;  3V6Q A;  3Q7D A;  2PT3 A;  1MHL C;  4MSF A;  3HS6 A;  5IKQ A;  3RR3 A;  5GLS A;  3LN0 A;  3FAQ A;  3ZS1 C;  1D7W C;  5IKT A;  2EFB A;  4PNX A;  3GC1 A;  1EQH A;  1MYP C;  2R5L A;  3N8Y B;  3N8Z A;  3Q9K A;  5KIR A;  3LN1 A;  3QF1 A;  2E9E A;  3UBA A;  3OGW A;  4HHS A;  5HPW A;  1D2V C;  1IGX A;  4RRX A;  5GH0 A;  4KVK A;  3N8W A;  3QL6 A;  3NT1 A;  3QMO A;  5JVY A;  1D5L C;  1EBV A;  5JW1 A;  3I6N A;  5B72 A;  1PTH A;  3HS7 A;  4NJB A;  3KRK A;  4OEK A;  3QH0 A;  2IPS A;  4M11 A;  3N8X A;  2IKC A;  1CXP C;  4DL1 C;  3PY4 A;  1CX2 A;  4OTJ A;  4RS0 A;  4FM5 A;  5JVZ A;  2QQT A;  2O86 A;  3BXI A;  4IG5 A;  1IGZ A;  5COX A;  3GCJ A;  4RRW A;  2EHA A;  3FNL A;  1FE2 A;  1DNU C;  5FF1 A;  3N8V A;  3NAK A;  1PRH A;  4E1G A;  4LJJ A;  4GN6 A;  5F1A A;  3GCL A;  3N8W B;  1DDX A;  2PUM A;  2OYU P;  1DNW C;  2QRB A;  3OLU A;  3MQE A;  4NT3 A;  3NTG A;  3F9P C;  4RUT A;  4HHR A;  2AYL A;  5FIW C;  3PGH A;  4C1M C;  5F19 A;  3S4F A; 
#chains in the Genus database with same CATH topology
 4PH9 A;  3NYH A;  4COX A;  3R5Q A;  3HS5 A;  1CQE A;  1Q4G A;  4RRZ A;  2OYE P;  4Z0L A;  3R4X A;  4KVJ A;  6COX A;  3ZS0 C;  2QPK A;  1DIY A;  1HT8 A;  2GJM A;  3SXV A;  3R55 A;  4OTY A;  4QJQ A;  3OLT A;  4QYQ A;  3GCK A;  4KSZ A;  3TGY A;  3NIU A;  3RKE A;  4M10 A;  3TZI A;  3N8F A;  3KK6 A;  3ERH A;  3NTB A;  1EQG A;  4RRY A;  3N8Y A;  4O1Z A;  4GM7 A;  2Z5Z A;  3R5O A;  3KRQ A;  1PXX A;  5IKR A;  1PGE A;  1HT5 A;  5FDQ A;  1U67 A;  4Y55 A;  3ERI A;  3MDL A;  4KVL A;  2NQX A;  5IKV A;  2OJV A;  1CVU A;  4N7A A;  3V6Q A;  3Q7D A;  2PT3 A;  1MHL C;  4MSF A;  3HS6 A;  5IKQ A;  3RR3 A;  5GLS A;  3LN0 A;  3FAQ A;  3ZS1 C;  1D7W C;  5IKT A;  2EFB A;  4PNX A;  3GC1 A;  1EQH A;  1MYP C;  2R5L A;  3N8Y B;  3N8Z A;  3Q9K A;  5KIR A;  3LN1 A;  3QF1 A;  2E9E A;  3UBA A;  3OGW A;  4HHS A;  5HPW A;  1D2V C;  1IGX A;  4RRX A;  5GH0 A;  4KVK A;  3N8W A;  3QL6 A;  3NT1 A;  3QMO A;  5JVY A;  1D5L C;  1EBV A;  5JW1 A;  3I6N A;  5B72 A;  1PTH A;  3HS7 A;  4NJB A;  3KRK A;  4OEK A;  3QH0 A;  2IPS A;  4M11 A;  3N8X A;  2IKC A;  1CXP C;  4DL1 C;  3PY4 A;  1CX2 A;  4OTJ A;  4RS0 A;  4FM5 A;  5JVZ A;  2QQT A;  2O86 A;  3BXI A;  4IG5 A;  1IGZ A;  5COX A;  3GCJ A;  4RRW A;  2EHA A;  3FNL A;  1FE2 A;  1DNU C;  5FF1 A;  3N8V A;  3NAK A;  1PRH A;  4E1G A;  4LJJ A;  4GN6 A;  5F1A A;  3GCL A;  3N8W B;  1DDX A;  2PUM A;  2OYU P;  1DNW C;  2QRB A;  3OLU A;  3MQE A;  4NT3 A;  3NTG A;  3F9P C;  4RUT A;  4HHR A;  2AYL A;  5FIW C;  3PGH A;  4C1M C;  5F19 A;  3S4F A; 
#chains in the Genus database with same CATH homology
 4PH9 A;  3NYH A;  4COX A;  3R5Q A;  3HS5 A;  1CQE A;  1Q4G A;  4RRZ A;  2OYE P;  4Z0L A;  3R4X A;  4KVJ A;  6COX A;  3ZS0 C;  2QPK A;  1DIY A;  1HT8 A;  2GJM A;  3SXV A;  3R55 A;  4OTY A;  4QJQ A;  3OLT A;  4QYQ A;  3GCK A;  4KSZ A;  3TGY A;  3NIU A;  3RKE A;  4M10 A;  3TZI A;  3N8F A;  3KK6 A;  3ERH A;  3NTB A;  1EQG A;  4RRY A;  3N8Y A;  4O1Z A;  4GM7 A;  2Z5Z A;  3R5O A;  3KRQ A;  1PXX A;  5IKR A;  1PGE A;  1HT5 A;  5FDQ A;  1U67 A;  4Y55 A;  3ERI A;  3MDL A;  4KVL A;  2NQX A;  5IKV A;  2OJV A;  1CVU A;  4N7A A;  3V6Q A;  3Q7D A;  2PT3 A;  1MHL C;  4MSF A;  3HS6 A;  5IKQ A;  3RR3 A;  5GLS A;  3LN0 A;  3FAQ A;  3ZS1 C;  1D7W C;  5IKT A;  2EFB A;  4PNX A;  3GC1 A;  1EQH A;  1MYP C;  2R5L A;  3N8Y B;  3N8Z A;  3Q9K A;  5KIR A;  3LN1 A;  3QF1 A;  2E9E A;  3UBA A;  3OGW A;  4HHS A;  5HPW A;  1D2V C;  1IGX A;  4RRX A;  5GH0 A;  4KVK A;  3N8W A;  3QL6 A;  3NT1 A;  3QMO A;  5JVY A;  1D5L C;  1EBV A;  5JW1 A;  3I6N A;  5B72 A;  1PTH A;  3HS7 A;  4NJB A;  3KRK A;  4OEK A;  3QH0 A;  2IPS A;  4M11 A;  3N8X A;  2IKC A;  1CXP C;  4DL1 C;  3PY4 A;  1CX2 A;  4OTJ A;  4RS0 A;  4FM5 A;  5JVZ A;  2QQT A;  2O86 A;  3BXI A;  4IG5 A;  1IGZ A;  5COX A;  3GCJ A;  4RRW A;  2EHA A;  3FNL A;  1FE2 A;  1DNU C;  5FF1 A;  3N8V A;  3NAK A;  1PRH A;  4E1G A;  4LJJ A;  4GN6 A;  5F1A A;  3GCL A;  3N8W B;  1DDX A;  2PUM A;  2OYU P;  1DNW C;  2QRB A;  3OLU A;  3MQE A;  4NT3 A;  3NTG A;  3F9P C;  4RUT A;  4HHR A;  2AYL A;  5FIW C;  3PGH A;  4C1M C;  5F19 A;  3S4F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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