2KEOA

Solution nmr structure of human protein hs00059, cytochrome-b5-like domain of the herc2 e3 ligase. northeast structural genomics consortium (nesg) target ht98a
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
92
structure length
92
Chain Sequence
EKVTLVRIADLENHNNDGGFWTVIDGKVYDIKDFQTQSLTENSILAQFAGEDPVVALEAALQFEDTRESMHAFCVGQYLEPDQEGVTIPDLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution NMR Structure of human protein HS00059
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Probable E3 ubiquitin-protein ligase HERC2
total genus 20
structure length 92
sequence length 92
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2009-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00173 Cyt-b5 Cytochrome b5-like Heme/Steroid binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.120.10 Alpha Beta Roll Flavocytochrome B2; Chain A, domain 1 Cytochrome b5-like heme/steroid binding domain 2keoA00
1B5MA 3LF5A 1LQXA 1LDCA 1CYOA 1EHBA 1DO9A 1T0GA 1AXXA 1U9MA 1M59A 1HKOA 3KS0A 1M20A 1J0QA 1AW3A 1EUEA 1AQAA 1AWPA 1MJ4A 2OZ0A 1ICCA 3MUSA 1ES1A 3OZZB 4HINA 1MNYA 1BLVA 1X3XA 1JEXA 4X8YA 1IEUA 1CXYA 2I89A 3X32A 3X34A 2AXXA 1NX7A 1J03A 3X35A 1F04A 1I5UA 1B5BA 2I96A 1M2IA 3NERA 1SH4A 2M33A 4B8NA 1BFXA 1LCOA 1LJ0A 3X33A 1M2MA 1F03A 1LR6A 1LTDA 2IBJA 1SOXA 2KEOA 1U9UA 1B5AA 1IB7A 1KBIA 1FCBA 1I8CA 4HILA 1IETA 1I87A
chains in the Genus database with same CATH superfamily
1B5MA 3LF5A 1LQXA 1LDCA 1CYOA 1EHBA 1DO9A 1T0GA 1AXXA 1U9MA 1M59A 1HKOA 3KS0A 1M20A 1J0QA 1AW3A 1EUEA 1AQAA 1AWPA 1MJ4A 2OZ0A 1ICCA 3MUSA 1ES1A 3OZZB 4HINA 1MNYA 1BLVA 1X3XA 1JEXA 4X8YA 1IEUA 1CXYA 2I89A 3X32A 3X34A 2AXXA 1NX7A 1J03A 3X35A 1F04A 1I5UA 1B5BA 2I96A 1M2IA 3NERA 1SH4A 2M33A 4B8NA 1BFXA 1LCOA 1LJ0A 3X33A 1M2MA 1F03A 1LR6A 1LTDA 2IBJA 1SOXA 2KEOA 1U9UA 1B5AA 1IB7A 1KBIA 1FCBA 1I8CA 4HILA 1IETA 1I87A
chains in the Genus database with same CATH topology
1B5MA 3LF5A 1LQXA 1LDCA 1CYOA 1EHBA 1DO9A 1T0GA 1AXXA 1U9MA 1M59A 1HKOA 3KS0A 1M20A 1J0QA 1AW3A 1EUEA 1AQAA 1AWPA 1MJ4A 2OZ0A 1ICCA 3MUSA 1ES1A 3OZZB 4HINA 1MNYA 1BLVA 1X3XA 1JEXA 4X8YA 1IEUA 1CXYA 2I89A 3X32A 3X34A 2AXXA 1NX7A 1J03A 3X35A 1F04A 1I5UA 1B5BA 2I96A 1M2IA 3NERA 1SH4A 2M33A 4B8NA 1BFXA 1LCOA 1LJ0A 3X33A 1M2MA 1F03A 1LR6A 1LTDA 2IBJA 1SOXA 2KEOA 1U9UA 1B5AA 1IB7A 1KBIA 1FCBA 1I8CA 4HILA 1IETA 1I87A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B5M A;  3LF5 A;  1LQX A;  1LDC A;  1CYO A;  1EHB A;  1DO9 A;  1T0G A;  1AXX A;  1U9M A;  1M59 A;  1HKO A;  3KS0 A;  1M20 A;  1J0Q A;  1AW3 A;  1EUE A;  1AQA A;  1AWP A;  1MJ4 A;  2OZ0 A;  1ICC A;  3MUS A;  1ES1 A;  3OZZ B;  4HIN A;  1MNY A;  1BLV A;  1X3X A;  1JEX A;  4X8Y A;  1IEU A;  1CXY A;  2I89 A;  3X32 A;  3X34 A;  2AXX A;  1NX7 A;  1J03 A;  3X35 A;  1F04 A;  1I5U A;  1B5B A;  2I96 A;  1M2I A;  3NER A;  1SH4 A;  2M33 A;  4B8N A;  1BFX A;  1LCO A;  1LJ0 A;  3X33 A;  1M2M A;  1F03 A;  1LR6 A;  1LTD A;  2IBJ A;  1SOX A;  2KEO A;  1U9U A;  1B5A A;  1IB7 A;  1KBI A;  1FCB A;  1I8C A;  4HIL A;  1IET A;  1I87 A; 
#chains in the Genus database with same CATH topology
 1B5M A;  3LF5 A;  1LQX A;  1LDC A;  1CYO A;  1EHB A;  1DO9 A;  1T0G A;  1AXX A;  1U9M A;  1M59 A;  1HKO A;  3KS0 A;  1M20 A;  1J0Q A;  1AW3 A;  1EUE A;  1AQA A;  1AWP A;  1MJ4 A;  2OZ0 A;  1ICC A;  3MUS A;  1ES1 A;  3OZZ B;  4HIN A;  1MNY A;  1BLV A;  1X3X A;  1JEX A;  4X8Y A;  1IEU A;  1CXY A;  2I89 A;  3X32 A;  3X34 A;  2AXX A;  1NX7 A;  1J03 A;  3X35 A;  1F04 A;  1I5U A;  1B5B A;  2I96 A;  1M2I A;  3NER A;  1SH4 A;  2M33 A;  4B8N A;  1BFX A;  1LCO A;  1LJ0 A;  3X33 A;  1M2M A;  1F03 A;  1LR6 A;  1LTD A;  2IBJ A;  1SOX A;  2KEO A;  1U9U A;  1B5A A;  1IB7 A;  1KBI A;  1FCB A;  1I8C A;  4HIL A;  1IET A;  1I87 A; 
#chains in the Genus database with same CATH homology
 1B5M A;  3LF5 A;  1LQX A;  1LDC A;  1CYO A;  1EHB A;  1DO9 A;  1T0G A;  1AXX A;  1U9M A;  1M59 A;  1HKO A;  3KS0 A;  1M20 A;  1J0Q A;  1AW3 A;  1EUE A;  1AQA A;  1AWP A;  1MJ4 A;  2OZ0 A;  1ICC A;  3MUS A;  1ES1 A;  3OZZ B;  4HIN A;  1MNY A;  1BLV A;  1X3X A;  1JEX A;  4X8Y A;  1IEU A;  1CXY A;  2I89 A;  3X32 A;  3X34 A;  2AXX A;  1NX7 A;  1J03 A;  3X35 A;  1F04 A;  1I5U A;  1B5B A;  2I96 A;  1M2I A;  3NER A;  1SH4 A;  2M33 A;  4B8N A;  1BFX A;  1LCO A;  1LJ0 A;  3X33 A;  1M2M A;  1F03 A;  1LR6 A;  1LTD A;  2IBJ A;  1SOX A;  2KEO A;  1U9U A;  1B5A A;  1IB7 A;  1KBI A;  1FCB A;  1I8C A;  4HIL A;  1IET A;  1I87 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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