2KEO | Genus

Total Genus 20

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	20
sequence length	92
structure length	92
Chain Sequence	EKVTLVRIADLENHNNDGGFWTVIDGKVYDIKDFQTQSLTENSILAQFAGEDPVVALEAALQFEDTRESMHAFCVGQYLEPDQEGVTIPDLG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Ligase
source organism	Homo sapiens
publication title	Solution NMR Structure of human protein HS00059 rcsb
molecule keywords	Probable E3 ubiquitin-protein ligase HERC2
total genus	20
structure length	92
sequence length	92
ec nomenclature	ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date	2009-01-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00173	Cyt-b5	Cytochrome b5-like Heme/Steroid binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.120.10	Alpha Beta	Roll	Flavocytochrome B2; Chain A, domain 1	Cytochrome b5-like heme/steroid binding domain	2keoA00

1T0GA 4B8NA 2I96A 1LDCA 3LF5A 1KBIA 3X35A 1MNYA 1MJ4A 1CXYA 2OZ0A 4X8YA 1IB7A 1J0QA 1HKOA 1IETA 1LJ0A 1AQAA 2KEOA 3X33A 1LQXA 1LTDA 1SOXA 2IBJA 1M2IA 2I89A 1X3XA 1BLVA 1J03A 1JEXA 1M2MA 3X34A 1NX7A 4HILA 1F04A 1I87A 1ES1A 4HINA 3MUSA 1IEUA 1I8CA 1EHBA 3NERA 1B5MA 1B5BA 1M20A 1AW3A 1U9UA 1ICCA 1DO9A 1AWPA 1SH4A 1EUEA 1CYOA 1F03A 1LR6A 3OZZB 1AXXA 1I5UA 1LCOA 1U9MA 1B5AA 2AXXA 3X32A 1FCBA 1M59A 1BFXA 3KS0A 2M33A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1T0G A;  4B8N A;  2I96 A;  1LDC A;  3LF5 A;  1KBI A;  3X35 A;  1MNY A;  1MJ4 A;  1CXY A;  2OZ0 A;  4X8Y A;  1IB7 A;  1J0Q A;  1HKO A;  1IET A;  1LJ0 A;  1AQA A;  2KEO A;  3X33 A;  1LQX A;  1LTD A;  1SOX A;  2IBJ A;  1M2I A;  2I89 A;  1X3X A;  1BLV A;  1J03 A;  1JEX A;  1M2M A;  3X34 A;  1NX7 A;  4HIL A;  1F04 A;  1I87 A;  1ES1 A;  4HIN A;  3MUS A;  1IEU A;  1I8C A;  1EHB A;  3NER A;  1B5M A;  1B5B A;  1M20 A;  1AW3 A;  1U9U A;  1ICC A;  1DO9 A;  1AWP A;  1SH4 A;  1EUE A;  1CYO A;  1F03 A;  1LR6 A;  3OZZ B;  1AXX A;  1I5U A;  1LCO A;  1U9M A;  1B5A A;  2AXX A;  3X32 A;  1FCB A;  1M59 A;  1BFX A;  3KS0 A;  2M33 A; 
#chains in the Genus database with same CATH topology
 1T0G A;  4B8N A;  2I96 A;  1LDC A;  3LF5 A;  1KBI A;  3X35 A;  1MNY A;  1MJ4 A;  1CXY A;  2OZ0 A;  4X8Y A;  1IB7 A;  1J0Q A;  1HKO A;  1IET A;  1LJ0 A;  1AQA A;  2KEO A;  3X33 A;  1LQX A;  1LTD A;  1SOX A;  2IBJ A;  1M2I A;  2I89 A;  1X3X A;  1BLV A;  1J03 A;  1JEX A;  1M2M A;  3X34 A;  1NX7 A;  4HIL A;  1F04 A;  1I87 A;  1ES1 A;  4HIN A;  3MUS A;  1IEU A;  1I8C A;  1EHB A;  3NER A;  1B5M A;  1B5B A;  1M20 A;  1AW3 A;  1U9U A;  1ICC A;  1DO9 A;  1AWP A;  1SH4 A;  1EUE A;  1CYO A;  1F03 A;  1LR6 A;  3OZZ B;  1AXX A;  1I5U A;  1LCO A;  1U9M A;  1B5A A;  2AXX A;  3X32 A;  1FCB A;  1M59 A;  1BFX A;  3KS0 A;  2M33 A; 
#chains in the Genus database with same CATH homology
 1T0G A;  4B8N A;  2I96 A;  1LDC A;  3LF5 A;  1KBI A;  3X35 A;  1MNY A;  1MJ4 A;  1CXY A;  2OZ0 A;  4X8Y A;  1IB7 A;  1J0Q A;  1HKO A;  1IET A;  1LJ0 A;  1AQA A;  2KEO A;  3X33 A;  1LQX A;  1LTD A;  1SOX A;  2IBJ A;  1M2I A;  2I89 A;  1X3X A;  1BLV A;  1J03 A;  1JEX A;  1M2M A;  3X34 A;  1NX7 A;  4HIL A;  1F04 A;  1I87 A;  1ES1 A;  4HIN A;  3MUS A;  1IEU A;  1I8C A;  1EHB A;  3NER A;  1B5M A;  1B5B A;  1M20 A;  1AW3 A;  1U9U A;  1ICC A;  1DO9 A;  1AWP A;  1SH4 A;  1EUE A;  1CYO A;  1F03 A;  1LR6 A;  3OZZ B;  1AXX A;  1I5U A;  1LCO A;  1U9M A;  1B5A A;  2AXX A;  3X32 A;  1FCB A;  1M59 A;  1BFX A;  3KS0 A;  2M33 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2KEOA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations