2KEOA

Solution nmr structure of human protein hs00059, cytochrome-b5-like domain of the herc2 e3 ligase. northeast structural genomics consortium (nesg) target ht98a
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
92
structure length
92
Chain Sequence
EKVTLVRIADLENHNNDGGFWTVIDGKVYDIKDFQTQSLTENSILAQFAGEDPVVALEAALQFEDTRESMHAFCVGQYLEPDQEGVTIPDLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution NMR Structure of human protein HS00059
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Probable E3 ubiquitin-protein ligase HERC2
total genus 20
structure length 92
sequence length 92
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2009-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00173 Cyt-b5 Cytochrome b5-like Heme/Steroid binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.120.10 Alpha Beta Roll Flavocytochrome B2; Chain A, domain 1 Cytochrome b5-like heme/steroid binding domain 2keoA00
1I87A 3LF5A 1IB7A 1LJ0A 1MNYA 1JEXA 1LCOA 2M33A 1DO9A 1J0QA 1SOXA 1IEUA 1LQXA 3KS0A 2I96A 3NERA 3X32A 1J03A 1T0GA 3MUSA 1I8CA 3OZZB 1BFXA 1IETA 2I89A 1EHBA 1AWPA 1U9MA 4HILA 1AQAA 2IBJA 1M59A 1F03A 1LDCA 1M2MA 1X3XA 1KBIA 2OZ0A 4X8YA 3X35A 1M2IA 1M20A 1B5MA 1LTDA 2KEOA 1AW3A 1HKOA 3X33A 3X34A 1LR6A 4HINA 1NX7A 1FCBA 4B8NA 1BLVA 1B5AA 1AXXA 1B5BA 1ES1A 1I5UA 1CXYA 1F04A 1CYOA 1U9UA 1EUEA 1ICCA 1MJ4A 1SH4A 2AXXA
chains in the Genus database with same CATH superfamily
1I87A 3LF5A 1IB7A 1LJ0A 1MNYA 1JEXA 1LCOA 2M33A 1DO9A 1J0QA 1SOXA 1IEUA 1LQXA 3KS0A 2I96A 3NERA 3X32A 1J03A 1T0GA 3MUSA 1I8CA 3OZZB 1BFXA 1IETA 2I89A 1EHBA 1AWPA 1U9MA 4HILA 1AQAA 2IBJA 1M59A 1F03A 1LDCA 1M2MA 1X3XA 1KBIA 2OZ0A 4X8YA 3X35A 1M2IA 1M20A 1B5MA 1LTDA 2KEOA 1AW3A 1HKOA 3X33A 3X34A 1LR6A 4HINA 1NX7A 1FCBA 4B8NA 1BLVA 1B5AA 1AXXA 1B5BA 1ES1A 1I5UA 1CXYA 1F04A 1CYOA 1U9UA 1EUEA 1ICCA 1MJ4A 1SH4A 2AXXA
chains in the Genus database with same CATH topology
1I87A 3LF5A 1IB7A 1LJ0A 1MNYA 1JEXA 1LCOA 2M33A 1DO9A 1J0QA 1SOXA 1IEUA 1LQXA 3KS0A 2I96A 3NERA 3X32A 1J03A 1T0GA 3MUSA 1I8CA 3OZZB 1BFXA 1IETA 2I89A 1EHBA 1AWPA 1U9MA 4HILA 1AQAA 2IBJA 1M59A 1F03A 1LDCA 1M2MA 1X3XA 1KBIA 2OZ0A 4X8YA 3X35A 1M2IA 1M20A 1B5MA 1LTDA 2KEOA 1AW3A 1HKOA 3X33A 3X34A 1LR6A 4HINA 1NX7A 1FCBA 4B8NA 1BLVA 1B5AA 1AXXA 1B5BA 1ES1A 1I5UA 1CXYA 1F04A 1CYOA 1U9UA 1EUEA 1ICCA 1MJ4A 1SH4A 2AXXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I87 A;  3LF5 A;  1IB7 A;  1LJ0 A;  1MNY A;  1JEX A;  1LCO A;  2M33 A;  1DO9 A;  1J0Q A;  1SOX A;  1IEU A;  1LQX A;  3KS0 A;  2I96 A;  3NER A;  3X32 A;  1J03 A;  1T0G A;  3MUS A;  1I8C A;  3OZZ B;  1BFX A;  1IET A;  2I89 A;  1EHB A;  1AWP A;  1U9M A;  4HIL A;  1AQA A;  2IBJ A;  1M59 A;  1F03 A;  1LDC A;  1M2M A;  1X3X A;  1KBI A;  2OZ0 A;  4X8Y A;  3X35 A;  1M2I A;  1M20 A;  1B5M A;  1LTD A;  2KEO A;  1AW3 A;  1HKO A;  3X33 A;  3X34 A;  1LR6 A;  4HIN A;  1NX7 A;  1FCB A;  4B8N A;  1BLV A;  1B5A A;  1AXX A;  1B5B A;  1ES1 A;  1I5U A;  1CXY A;  1F04 A;  1CYO A;  1U9U A;  1EUE A;  1ICC A;  1MJ4 A;  1SH4 A;  2AXX A; 
#chains in the Genus database with same CATH topology
 1I87 A;  3LF5 A;  1IB7 A;  1LJ0 A;  1MNY A;  1JEX A;  1LCO A;  2M33 A;  1DO9 A;  1J0Q A;  1SOX A;  1IEU A;  1LQX A;  3KS0 A;  2I96 A;  3NER A;  3X32 A;  1J03 A;  1T0G A;  3MUS A;  1I8C A;  3OZZ B;  1BFX A;  1IET A;  2I89 A;  1EHB A;  1AWP A;  1U9M A;  4HIL A;  1AQA A;  2IBJ A;  1M59 A;  1F03 A;  1LDC A;  1M2M A;  1X3X A;  1KBI A;  2OZ0 A;  4X8Y A;  3X35 A;  1M2I A;  1M20 A;  1B5M A;  1LTD A;  2KEO A;  1AW3 A;  1HKO A;  3X33 A;  3X34 A;  1LR6 A;  4HIN A;  1NX7 A;  1FCB A;  4B8N A;  1BLV A;  1B5A A;  1AXX A;  1B5B A;  1ES1 A;  1I5U A;  1CXY A;  1F04 A;  1CYO A;  1U9U A;  1EUE A;  1ICC A;  1MJ4 A;  1SH4 A;  2AXX A; 
#chains in the Genus database with same CATH homology
 1I87 A;  3LF5 A;  1IB7 A;  1LJ0 A;  1MNY A;  1JEX A;  1LCO A;  2M33 A;  1DO9 A;  1J0Q A;  1SOX A;  1IEU A;  1LQX A;  3KS0 A;  2I96 A;  3NER A;  3X32 A;  1J03 A;  1T0G A;  3MUS A;  1I8C A;  3OZZ B;  1BFX A;  1IET A;  2I89 A;  1EHB A;  1AWP A;  1U9M A;  4HIL A;  1AQA A;  2IBJ A;  1M59 A;  1F03 A;  1LDC A;  1M2M A;  1X3X A;  1KBI A;  2OZ0 A;  4X8Y A;  3X35 A;  1M2I A;  1M20 A;  1B5M A;  1LTD A;  2KEO A;  1AW3 A;  1HKO A;  3X33 A;  3X34 A;  1LR6 A;  4HIN A;  1NX7 A;  1FCB A;  4B8N A;  1BLV A;  1B5A A;  1AXX A;  1B5B A;  1ES1 A;  1I5U A;  1CXY A;  1F04 A;  1CYO A;  1U9U A;  1EUE A;  1ICC A;  1MJ4 A;  1SH4 A;  2AXX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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