3GC1A

Crystal structure of bovine lactoperoxidase
Total Genus 173
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mode of binding of the tuberculosis prodrug isoniazid to heme peroxidases: binding studies and crystal structure of bovine lactoperoxidase with isoniazid at 2.7 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Lactoperoxidase
total genus 173
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2009-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 3gc1A00
3R5QA 1EQHA 3MQEA 5IKRA 4OTYA 3V6QA 5IKTA 3KRKA 3KRQA 3N8WB 2R5LA 2PUMA 1CVUA 3N8FA 1DDXA 3ERHA 3NTGA 5B72A 4RRWA 5JVYA 3BXIA 1U67A 3LN0A 5IKQA 2E9EA 1Q4GA 1DNUC 1CQEA 1PGEA 4PNXA 5KIRA 4RRYA 3QMOA 4E1GA 1IGXA 3TGYA 3FNLA 3N8YA 3NIUA 2QRBA 3N8XA 1D2VC 1CXPC 3R5OA 4N7AA 1D7WC 3Q7DA 3I6NA 1FE2A 3QH0A 2NQXA 2QPKA 2QQTA 4QYQA 3TZIA 4O1ZA 3ZS1C 5FIWC 3OGWA 4PH9A 4NJBA 2GJMA 3OLTA 1MHLC 1PTHA 4HHRA 3KK6A 3UBAA 1DIYA 3HS5A 2IPSA 3OLUA 4GM7A 5GH0A 4M10A 4IG5A 4GN6A 4NT3A 5IKVA 1CX2A 1HT5A 4Y55A 5COXA 4MSFA 3NT1A 4Z0LA 3N8YB 3GCLA 2O86A 3F9PC 3PY4A 1EQGA 3GC1A 3R55A 2PT3A 5FF1A 5GLSA 2Z5ZA 4KVJA 5JVZA 3GCKA 3QF1A 2AYLA 2OYEP 3ZS0C 1IGZA 3HS7A 3MDLA 4OEKA 3ERIA 4RS0A 4RRZA 1PRHA 4KSZA 5FDQA 3RKEA 3NYHA 3N8WA 1DNWC 3N8ZA 4OTJA 2EFBA 3RR3A 3QL6A 5HPWA 2EHAA 4M11A 5F1AA 4COXA 4DL1C 6COXA 3NTBA 3R4XA 4QJQA 3FAQA 2OYUP 3Q9KA 3GCJA 4HHSA 3S4FA 2IKCA 3N8VA 4RRXA 1PXXA 3HS6A 3PGHA 4LJJA 1D5LC 1MYPC 1HT8A 4C1MC 4RUTA 4KVKA 5F19A 4KVLA 3SXVA 3LN1A 5JW1A 4FM5A 1EBVA 3NAKA 2OJVA
chains in the Genus database with same CATH superfamily
3R5QA 1EQHA 3MQEA 5IKRA 4OTYA 3V6QA 5IKTA 3KRKA 3KRQA 3N8WB 2R5LA 2PUMA 1CVUA 3N8FA 1DDXA 3ERHA 3NTGA 5B72A 4RRWA 5JVYA 3BXIA 1U67A 3LN0A 5IKQA 2E9EA 1Q4GA 1DNUC 1CQEA 1PGEA 4PNXA 5KIRA 4RRYA 3QMOA 4E1GA 1IGXA 3TGYA 3FNLA 3N8YA 3NIUA 2QRBA 3N8XA 1D2VC 1CXPC 3R5OA 4N7AA 1D7WC 3Q7DA 3I6NA 1FE2A 3QH0A 2NQXA 2QPKA 2QQTA 4QYQA 3TZIA 4O1ZA 3ZS1C 5FIWC 3OGWA 4PH9A 4NJBA 2GJMA 3OLTA 1MHLC 1PTHA 4HHRA 3KK6A 3UBAA 1DIYA 3HS5A 2IPSA 3OLUA 4GM7A 5GH0A 4M10A 4IG5A 4GN6A 4NT3A 5IKVA 1CX2A 1HT5A 4Y55A 5COXA 4MSFA 3NT1A 4Z0LA 3N8YB 3GCLA 2O86A 3F9PC 3PY4A 1EQGA 3GC1A 3R55A 2PT3A 5FF1A 5GLSA 2Z5ZA 4KVJA 5JVZA 3GCKA 3QF1A 2AYLA 2OYEP 3ZS0C 1IGZA 3HS7A 3MDLA 4OEKA 3ERIA 4RS0A 4RRZA 1PRHA 4KSZA 5FDQA 3RKEA 3NYHA 3N8WA 1DNWC 3N8ZA 4OTJA 2EFBA 3RR3A 3QL6A 5HPWA 2EHAA 4M11A 5F1AA 4COXA 4DL1C 6COXA 3NTBA 3R4XA 4QJQA 3FAQA 2OYUP 3Q9KA 3GCJA 4HHSA 3S4FA 2IKCA 3N8VA 4RRXA 1PXXA 3HS6A 3PGHA 4LJJA 1D5LC 1MYPC 1HT8A 4C1MC 4RUTA 4KVKA 5F19A 4KVLA 3SXVA 3LN1A 5JW1A 4FM5A 1EBVA 3NAKA 2OJVA
chains in the Genus database with same CATH topology
3R5QA 1EQHA 3MQEA 5IKRA 4OTYA 3V6QA 5IKTA 3KRKA 3KRQA 3N8WB 2R5LA 2PUMA 1CVUA 3N8FA 1DDXA 3ERHA 3NTGA 5B72A 4RRWA 5JVYA 3BXIA 1U67A 3LN0A 5IKQA 2E9EA 1Q4GA 1DNUC 1CQEA 1PGEA 4PNXA 5KIRA 4RRYA 3QMOA 4E1GA 1IGXA 3TGYA 3FNLA 3N8YA 3NIUA 2QRBA 3N8XA 1D2VC 1CXPC 3R5OA 4N7AA 1D7WC 3Q7DA 3I6NA 1FE2A 3QH0A 2NQXA 2QPKA 2QQTA 4QYQA 3TZIA 4O1ZA 3ZS1C 5FIWC 3OGWA 4PH9A 4NJBA 2GJMA 3OLTA 1MHLC 1PTHA 4HHRA 3KK6A 3UBAA 1DIYA 3HS5A 2IPSA 3OLUA 4GM7A 5GH0A 4M10A 4IG5A 4GN6A 4NT3A 5IKVA 1CX2A 1HT5A 4Y55A 5COXA 4MSFA 3NT1A 4Z0LA 3N8YB 3GCLA 2O86A 3F9PC 3PY4A 1EQGA 3GC1A 3R55A 2PT3A 5FF1A 5GLSA 2Z5ZA 4KVJA 5JVZA 3GCKA 3QF1A 2AYLA 2OYEP 3ZS0C 1IGZA 3HS7A 3MDLA 4OEKA 3ERIA 4RS0A 4RRZA 1PRHA 4KSZA 5FDQA 3RKEA 3NYHA 3N8WA 1DNWC 3N8ZA 4OTJA 2EFBA 3RR3A 3QL6A 5HPWA 2EHAA 4M11A 5F1AA 4COXA 4DL1C 6COXA 3NTBA 3R4XA 4QJQA 3FAQA 2OYUP 3Q9KA 3GCJA 4HHSA 3S4FA 2IKCA 3N8VA 4RRXA 1PXXA 3HS6A 3PGHA 4LJJA 1D5LC 1MYPC 1HT8A 4C1MC 4RUTA 4KVKA 5F19A 4KVLA 3SXVA 3LN1A 5JW1A 4FM5A 1EBVA 3NAKA 2OJVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R5Q A;  1EQH A;  3MQE A;  5IKR A;  4OTY A;  3V6Q A;  5IKT A;  3KRK A;  3KRQ A;  3N8W B;  2R5L A;  2PUM A;  1CVU A;  3N8F A;  1DDX A;  3ERH A;  3NTG A;  5B72 A;  4RRW A;  5JVY A;  3BXI A;  1U67 A;  3LN0 A;  5IKQ A;  2E9E A;  1Q4G A;  1DNU C;  1CQE A;  1PGE A;  4PNX A;  5KIR A;  4RRY A;  3QMO A;  4E1G A;  1IGX A;  3TGY A;  3FNL A;  3N8Y A;  3NIU A;  2QRB A;  3N8X A;  1D2V C;  1CXP C;  3R5O A;  4N7A A;  1D7W C;  3Q7D A;  3I6N A;  1FE2 A;  3QH0 A;  2NQX A;  2QPK A;  2QQT A;  4QYQ A;  3TZI A;  4O1Z A;  3ZS1 C;  5FIW C;  3OGW A;  4PH9 A;  4NJB A;  2GJM A;  3OLT A;  1MHL C;  1PTH A;  4HHR A;  3KK6 A;  3UBA A;  1DIY A;  3HS5 A;  2IPS A;  3OLU A;  4GM7 A;  5GH0 A;  4M10 A;  4IG5 A;  4GN6 A;  4NT3 A;  5IKV A;  1CX2 A;  1HT5 A;  4Y55 A;  5COX A;  4MSF A;  3NT1 A;  4Z0L A;  3N8Y B;  3GCL A;  2O86 A;  3F9P C;  3PY4 A;  1EQG A;  3GC1 A;  3R55 A;  2PT3 A;  5FF1 A;  5GLS A;  2Z5Z A;  4KVJ A;  5JVZ A;  3GCK A;  3QF1 A;  2AYL A;  2OYE P;  3ZS0 C;  1IGZ A;  3HS7 A;  3MDL A;  4OEK A;  3ERI A;  4RS0 A;  4RRZ A;  1PRH A;  4KSZ A;  5FDQ A;  3RKE A;  3NYH A;  3N8W A;  1DNW C;  3N8Z A;  4OTJ A;  2EFB A;  3RR3 A;  3QL6 A;  5HPW A;  2EHA A;  4M11 A;  5F1A A;  4COX A;  4DL1 C;  6COX A;  3NTB A;  3R4X A;  4QJQ A;  3FAQ A;  2OYU P;  3Q9K A;  3GCJ A;  4HHS A;  3S4F A;  2IKC A;  3N8V A;  4RRX A;  1PXX A;  3HS6 A;  3PGH A;  4LJJ A;  1D5L C;  1MYP C;  1HT8 A;  4C1M C;  4RUT A;  4KVK A;  5F19 A;  4KVL A;  3SXV A;  3LN1 A;  5JW1 A;  4FM5 A;  1EBV A;  3NAK A;  2OJV A; 
#chains in the Genus database with same CATH topology
 3R5Q A;  1EQH A;  3MQE A;  5IKR A;  4OTY A;  3V6Q A;  5IKT A;  3KRK A;  3KRQ A;  3N8W B;  2R5L A;  2PUM A;  1CVU A;  3N8F A;  1DDX A;  3ERH A;  3NTG A;  5B72 A;  4RRW A;  5JVY A;  3BXI A;  1U67 A;  3LN0 A;  5IKQ A;  2E9E A;  1Q4G A;  1DNU C;  1CQE A;  1PGE A;  4PNX A;  5KIR A;  4RRY A;  3QMO A;  4E1G A;  1IGX A;  3TGY A;  3FNL A;  3N8Y A;  3NIU A;  2QRB A;  3N8X A;  1D2V C;  1CXP C;  3R5O A;  4N7A A;  1D7W C;  3Q7D A;  3I6N A;  1FE2 A;  3QH0 A;  2NQX A;  2QPK A;  2QQT A;  4QYQ A;  3TZI A;  4O1Z A;  3ZS1 C;  5FIW C;  3OGW A;  4PH9 A;  4NJB A;  2GJM A;  3OLT A;  1MHL C;  1PTH A;  4HHR A;  3KK6 A;  3UBA A;  1DIY A;  3HS5 A;  2IPS A;  3OLU A;  4GM7 A;  5GH0 A;  4M10 A;  4IG5 A;  4GN6 A;  4NT3 A;  5IKV A;  1CX2 A;  1HT5 A;  4Y55 A;  5COX A;  4MSF A;  3NT1 A;  4Z0L A;  3N8Y B;  3GCL A;  2O86 A;  3F9P C;  3PY4 A;  1EQG A;  3GC1 A;  3R55 A;  2PT3 A;  5FF1 A;  5GLS A;  2Z5Z A;  4KVJ A;  5JVZ A;  3GCK A;  3QF1 A;  2AYL A;  2OYE P;  3ZS0 C;  1IGZ A;  3HS7 A;  3MDL A;  4OEK A;  3ERI A;  4RS0 A;  4RRZ A;  1PRH A;  4KSZ A;  5FDQ A;  3RKE A;  3NYH A;  3N8W A;  1DNW C;  3N8Z A;  4OTJ A;  2EFB A;  3RR3 A;  3QL6 A;  5HPW A;  2EHA A;  4M11 A;  5F1A A;  4COX A;  4DL1 C;  6COX A;  3NTB A;  3R4X A;  4QJQ A;  3FAQ A;  2OYU P;  3Q9K A;  3GCJ A;  4HHS A;  3S4F A;  2IKC A;  3N8V A;  4RRX A;  1PXX A;  3HS6 A;  3PGH A;  4LJJ A;  1D5L C;  1MYP C;  1HT8 A;  4C1M C;  4RUT A;  4KVK A;  5F19 A;  4KVL A;  3SXV A;  3LN1 A;  5JW1 A;  4FM5 A;  1EBV A;  3NAK A;  2OJV A; 
#chains in the Genus database with same CATH homology
 3R5Q A;  1EQH A;  3MQE A;  5IKR A;  4OTY A;  3V6Q A;  5IKT A;  3KRK A;  3KRQ A;  3N8W B;  2R5L A;  2PUM A;  1CVU A;  3N8F A;  1DDX A;  3ERH A;  3NTG A;  5B72 A;  4RRW A;  5JVY A;  3BXI A;  1U67 A;  3LN0 A;  5IKQ A;  2E9E A;  1Q4G A;  1DNU C;  1CQE A;  1PGE A;  4PNX A;  5KIR A;  4RRY A;  3QMO A;  4E1G A;  1IGX A;  3TGY A;  3FNL A;  3N8Y A;  3NIU A;  2QRB A;  3N8X A;  1D2V C;  1CXP C;  3R5O A;  4N7A A;  1D7W C;  3Q7D A;  3I6N A;  1FE2 A;  3QH0 A;  2NQX A;  2QPK A;  2QQT A;  4QYQ A;  3TZI A;  4O1Z A;  3ZS1 C;  5FIW C;  3OGW A;  4PH9 A;  4NJB A;  2GJM A;  3OLT A;  1MHL C;  1PTH A;  4HHR A;  3KK6 A;  3UBA A;  1DIY A;  3HS5 A;  2IPS A;  3OLU A;  4GM7 A;  5GH0 A;  4M10 A;  4IG5 A;  4GN6 A;  4NT3 A;  5IKV A;  1CX2 A;  1HT5 A;  4Y55 A;  5COX A;  4MSF A;  3NT1 A;  4Z0L A;  3N8Y B;  3GCL A;  2O86 A;  3F9P C;  3PY4 A;  1EQG A;  3GC1 A;  3R55 A;  2PT3 A;  5FF1 A;  5GLS A;  2Z5Z A;  4KVJ A;  5JVZ A;  3GCK A;  3QF1 A;  2AYL A;  2OYE P;  3ZS0 C;  1IGZ A;  3HS7 A;  3MDL A;  4OEK A;  3ERI A;  4RS0 A;  4RRZ A;  1PRH A;  4KSZ A;  5FDQ A;  3RKE A;  3NYH A;  3N8W A;  1DNW C;  3N8Z A;  4OTJ A;  2EFB A;  3RR3 A;  3QL6 A;  5HPW A;  2EHA A;  4M11 A;  5F1A A;  4COX A;  4DL1 C;  6COX A;  3NTB A;  3R4X A;  4QJQ A;  3FAQ A;  2OYU P;  3Q9K A;  3GCJ A;  4HHS A;  3S4F A;  2IKC A;  3N8V A;  4RRX A;  1PXX A;  3HS6 A;  3PGH A;  4LJJ A;  1D5L C;  1MYP C;  1HT8 A;  4C1M C;  4RUT A;  4KVK A;  5F19 A;  4KVL A;  3SXV A;  3LN1 A;  5JW1 A;  4FM5 A;  1EBV A;  3NAK A;  2OJV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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