3L3L | Genus

Total Genus 101

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	101
sequence length	350
structure length	350
Chain Sequence	KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 350 atoms

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350 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/transferase inhibitor
source organism	Homo sapiens
publication title	Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. pubmed doi rcsb
molecule keywords	Poly [ADP-ribose] polymerase 1
total genus	101
structure length	350
sequence length	350
ec nomenclature	ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date	2009-12-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00644	PARP	Poly(ADP-ribose) polymerase catalytic domain
A	PF02877	PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.142.10	Mainly Alpha	Up-down Bundle	Poly(ADP-ribose) Polymerase; domain 1	Poly(ADP-ribose) polymerase, regulatory domain	3l3lA01
3.90.228.10	Alpha Beta	Alpha-Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 3	Phosphoenolpyruvate Carboxykinase; domain 3	3l3lA02

4L6ZA 4KZUA 4UVSA 4BJBA 4HLHA 4LI6A 5C5QA 4L33A 4KZQA 4BS4A 3PAXA 4OQBC 4UI3A 2PQFA 4PNTA 5ETYA 4L32A 4UI8A 4AVUA 4F1QA 4TJUA 4U6AA 4L0VA 4MSKA 3CE0A 5ADTA 4F0EA 1EFYA 4UFYA 4PNNA 5EBTA 4L6SA 4L0SA 3C49A 3MHKA 4PJTA 3KR7A 4L7RA 1GS0A 4UXBA 4PNSA 4UUHA 4W5IA 4BUTA 4BUYA 4UVXA 3U9HA 4L70A 4IUEA 3SMJA 4BJ9A 4TVJA 4HLGA 4PNRA 4N3RA 4UNDA 4UI6A 3P0NA 4UFUA 4HYFA 4BU5A 5ADRA 4TKFA 4TK5A 5AL4A 4LI8A 4L0IA 4OPXC 4ZZXA 5AL5A 3KR8A 4J22A 4PNQA 3BLJA 5ADSA 5FPGA 3KJDA 4BUIA 5AKUA 3MHJA 3KCZA 1PAXA 2RCWA 4L34A 4ZZZA 4KZLA 4HLKA 4L0TA 5ECEA 4F1LA 4L2GA 4UVVA 4PMLA 4ZZYA 4HLMA 4OA7A 4UI7A 4UVOA 4J3MA 4K4FA 3U9YA 4L2KA 4UI4A 4UVPA 4L2FA 4RV6A 4PNMA 4L7OA 4W5SA 4BUEA 4BUVA 3GEYA 4TJYA 4BU8A 1UK1A 4UX4A 4HLFA 4J1ZA 2PAXA 4TK0A 5LXPA 1UK0A 3UH4A 4UVZA 4HHYA 4J3LA 4X52A 3P0PA 5FPFA 5AL2A 4BUDA 5C5PA 4TKGA 4DVIA 3HKVA 4MT9A 4PNLA 4L7UA 4GV7A 4R5WA 3L3LA 5AEHA 4UI5A 4UVLA 4N4VA 1WOKA 4I9IA 2X5YA 4XHUA 3GN7A 4UVYA 5AL3A 4UVUA 4BUUA 5LYHA 3SMIA 4BU9A 3UH2A 5C5RA 2RF5A 5ADQA 4HKKA 5DCZA 4BJCA 4L7PA 2PAWA 3P0QA 4GV4A 4TORA 4R6EA 4KRSA 4L10A 4UW1A 4BUFA 4GV0A 5LX6A 4BU3A 4L7NA 4BUWA 1A26A 3SE2A 4BFPA 4PAXA 4L09A 4BU6A 4BUSA 3C4HA 4J21A 4PJVA 4K4EA 4HKNA 4BUXA 4L7LA 4TJWA 4BU7A 2RD6A 4UVWA 3UA9A 3UDDA 4AVWA 4BUAA 4LI7A 4UHGA 5A00A 4TKIA 4HHZA 4HMHA 4TOSA 5AKWA 4PY4A 3W51A 5AL1A 4L31A 4MSGA 3FHBA 3GJWA 4DQYC 4GV2A 4UVNA 4W6EA 4UVTA 4L0BA 4HKIA 3L3MA 4HL5A 4M7BA 4OQAC 4N4TA 3GOYA
chains in the Genus database with same CATH superfamily

4KZUA 4HLHA 4BS4A 4UI3A 1YTMA 4F1QA 4IDXA 5FH1A 4L0SA 3MHKA 4YWDA 3KR7A 4W5IA 4BUTA 4BUYA 4L70A 4BJ9A 3MOHA 4UFUA 4HYFA 4OPXC 4ZZXA 3KR8A 4BUIA 5AKUA 3MHJA 4KZLA 4L0TA 1K3DA 4F1LA 4OA7A 4WPTA 4J3MA 1M51A 4UVPA 4L2FA 4L7OA 4W5SA 4BUEA 4BUVA 4HLFA 4J1ZA 2PAXA 1UK0A 4UVZA 4HHYA 4TKGA 4MT9A 4PNLA 5FH3A 3L3LA 2RK8A 4UVYA 5AL3A 4R6EA 4GNPA 4PAXA 4J21A 1YVYA 1OS1A 3UA9A 4LI7A 3DTBA 4GNMA 4HMHA 3GJWA 4GMUA 3L3MA 4HL5A 4N4TA 3GOYA 4XHUA 4L6ZA 4UVSA 4BJBA 5C5QA 1YGGA 4PNTA 5FH4A 4U6AA 4MSKA 3CE0A 4UFYA 4PNNA 5EBTA 4L6SA 1YLHA 4GMZA 2OLQA 1GS0A 2RKEA 4UVXA 4GNQA 4UNDA 3DT2A 3P0NA 4BU5A 5AL5A 3ZL9A 5FPGA 2QZYA 4ZZZA 5ECEA 2QF2A 4UVVA 4WOUA 1AYLA 3U9YA 4UI4A 2RKDA 3GEYA 5LXPA 3P0PA 5FPFA 4OX2A 4UVLA 5ADQA 4HKKA 4BJCA 4IJSA 2OLRA 3P0QA 2PY7X 4TORA 4UW1A 5LX6A 1OENA 4BU3A 4BUWA 3SE2A 4L09A 5I67A 4BU6A 1J3BA 4BUSA 4PJVA 4YW8A 4BUXA 4JNGA 4TJWA 4UHGA 4YWBA 4WPUA 4L0BA 2QEWA 4YW9A 2QEYA 4AVUA 5ADTA 3C49A 4PJTA 4UXBA 3U9HA 4TVJA 4HLGA 4PNRA 2ZCIA 5ADRA 4TKFA 5AL4A 3DT7A 4L0IA 4GNLA 5FH5A 4J22A 4PNQA 4WIUA 4BHHB 1PAXA 4IDUB 1K3CA 4L34A 4HLKA 4ZZYA 4UI7A 4K4FA 4WL8A 4L2KA 4RV6A 3DT4A 1KHEA 4TJYA 4BU8A 1UK1A 4TK0A 4J3LA 4X52A 5AL2A 5C5PA 4DVIA 3HKVA 4L7UA 4GV7A 4R5WA 5AEHA 4I9IA 2X5YA 1KHFA 3MOFA 5LYHA 4J1JA 4UVUA 4BU9A 2PC9A 5C5RA 2RF5A 4L7PA 2PAWA 4BUFA 4GV0A 1AQ2A 4L7NA 4BFPA 3C4HA 4K4EA 4HKNA 3MOEA 4IDUA 1KHBA 4BU7A 2RD6A 4UVWA 4BUAA 2RKAA 4PY4A 3W51A 4GV2A 4UVNA 4J1GA 4HKIA 4KZQA 2QF1A 4WIEA 4LI6A 4L33A 3PAXA 4OQBC 2PQFA 5ETYA 4L32A 4UI8A 4TJUA 4F0EA 1EFYA 3ZLAA 4PNSA 4L7RA 4UUHA 4GMWA 4BGPA 4IUEA 3SMJA 4N3RA 4UI6A 2PXZX 4TK5A 4LI8A 2FAFA 3BLJA 5ADSA 3KJDA 2GMVA 3KCZA 2RCWA 4L2GA 5FH2A 4PMLA 4HLMA 4UVOA 2FAHA 4PNMA 2RK7A 4R43A 4UX4A 3UH4A 4BUDA 1II2A 1XKVA 4UI5A 4N4VA 1WOKA 4GNOA 3GN7A 4BUUA 3SMIA 3UH2A 4RCGA 4GMMA 5DCZA 4GV4A 4KRSA 4L10A 4WPVA 1A26A 4L7LA 1NHXA 3UDDA 4AVWA 5A00A 4TKIA 4HHZA 1KHGA 4TOSA 5AKWA 5AL1A 4L31A 4MSGA 3FHBA 4DQYC 4W6EA 5FH0A 4UVTA 4M7BA 4OQAC 4L0VA
chains in the Genus database with same CATH topology

4L6ZA 2QEWA 4KZUA 4UVSA 4BJBA 4WIEA 4HLHA 4LI6A 5C5QA 4L33A 1YGGA 4KZQA 4YW9A 3PAXA 4BS4A 4OQBC 4UI3A 1YTMA 2PQFA 2QEYA 4PNTA 5ETYA 5FH4A 4L32A 4UI8A 4AVUA 4F1QA 4TJUA 4U6AA 4L0VA 4MSKA 3CE0A 5ADTA 4F0EA 1EFYA 4UFYA 4PNNA 5EBTA 4L6SA 4L0SA 5FH1A 3C49A 3MHKA 4YWDA 1YLHA 4GMZA 4PJTA 3KR7A 4L7RA 1GS0A 4UXBA 2OLQA 4PNSA 4GMWA 2RKEA 4UUHA 4UVXA 4W5IA 3U9HA 4BUTA 4BUYA 4L70A 4IUEA 3SMJA 4GNQA 4BJ9A 4TVJA 4HLGA 4PNRA 4N3RA 4UNDA 3DT2A 3MOHA 4UI6A 2PXZX 3P0NA 2ZCIA 4UFUA 4HYFA 4BU5A 5ADRA 4TKFA 4TK5A 5AL4A 4LI8A 3DT7A 4L0IA 4OPXC 4ZZXA 4GNLA 5AL5A 5FH5A 3KR8A 4J22A 4PNQA 2FAFA 3BLJA 4WIUA 5ADSA 5FPGA 3KJDA 2GMVA 4BUIA 5AKUA 2QZYA 3KCZA 1PAXA 3MHJA 2RCWA 1K3CA 4L34A 4ZZZA 4KZLA 4HLKA 4L0TA 5ECEA 1K3DA 2QF2A 4L2GA 4UVVA 4PMLA 5FH2A 4WOUA 4ZZYA 4HLMA 4OA7A 4UI7A 1AYLA 4UVOA 4J3MA 4K4FA 1M51A 4WL8A 4WPTA 4L2KA 4UI4A 2RKDA 4UVPA 4L2FA 4RV6A 2FAHA 4PNMA 3DT4A 1KHEA 4L7OA 4W5SA 4BUEA 2RK7A 4BUVA 3GEYA 4TJYA 4F1LA 4BU8A 1UK1A 4R43A 4UX4A 4HLFA 4J1ZA 2PAXA 4TK0A 5LXPA 1UK0A 3UH4A 4UVZA 4HHYA 4J3LA 4X52A 3P0PA 5FPFA 5AL2A 4BUDA 1II2A 5C5PA 4TKGA 4DVIA 3HKVA 4MT9A 4PNLA 4OX2A 4L7UA 4GV7A 4R5WA 5FH3A 3L3LA 1XKVA 5AEHA 4UI5A 4UVLA 4N4VA 1WOKA 2RK8A 4I9IA 2X5YA 4GNOA 1KHFA 3GN7A 3MOFA 4UVYA 4UVUA 5AL3A 4BUUA 5LYHA 3SMIA 4BU9A 3UH2A 4BUFA 4RCGA 4GMMA 2PC9A 4N4TA 5C5RA 2RF5A 5ADQA 4HKKA 5DCZA 4BJCA 4L7PA 2PAWA 2OLRA 4GV4A 2PY7X 4R6EA 3P0QA 4KRSA 4GNPA 4L10A 4GV0A 4TORA 1OENA 4UW1A 5LX6A 4WPVA 4BU3A 1AQ2A 4L7NA 4BUWA 1A26A 3SE2A 3GOYA 4BFPA 4PAXA 4L09A 5I67A 4BU6A 1J3BA 4BUSA 3C4HA 4J21A 4PJVA 4K4EA 1YVYA 4HKNA 3MOEA 4YW8A 4BUXA 4L7LA 1KHBA 1OS1A 4TJWA 4BU7A 2RD6A 1NHXA 4UVWA 3UDDA 3U9YA 3UA9A 4AVWA 4BUAA 4LI7A 2RKAA 4UHGA 5A00A 4YWBA 4TKIA 3DTBA 4WPUA 4HHZA 1KHGA 4GNMA 4HMHA 4TOSA 5AKWA 4PY4A 3W51A 5AL1A 4L31A 4MSGA 3FHBA 3GJWA 4DQYC 4GV2A 4UVNA 4GMUA 4W6EA 5FH0A 4UVTA 4L0BA 4HKIA 3L3MA 4HL5A 4M7BA 4OQAC 2QF1A 4XHUA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4L6Z A;  4KZU A;  4UVS A;  4BJB A;  4HLH A;  4LI6 A;  5C5Q A;  4L33 A;  4KZQ A;  4BS4 A;  3PAX A;  4OQB C;  4UI3 A;  2PQF A;  4PNT A;  5ETY A;  4L32 A;  4UI8 A;  4AVU A;  4F1Q A;  4TJU A;  4U6A A;  4L0V A;  4MSK A;  3CE0 A;  5ADT A;  4F0E A;  1EFY A;  4UFY A;  4PNN A;  5EBT A;  4L6S A;  4L0S A;  3C49 A;  3MHK A;  4PJT A;  3KR7 A;  4L7R A;  1GS0 A;  4UXB A;  4PNS A;  4UUH A;  4W5I A;  4BUT A;  4BUY A;  4UVX A;  3U9H A;  4L70 A;  4IUE A;  3SMJ A;  4BJ9 A;  4TVJ A;  4HLG A;  4PNR A;  4N3R A;  4UND A;  4UI6 A;  3P0N A;  4UFU A;  4HYF A;  4BU5 A;  5ADR A;  4TKF A;  4TK5 A;  5AL4 A;  4LI8 A;  4L0I A;  4OPX C;  4ZZX A;  5AL5 A;  3KR8 A;  4J22 A;  4PNQ A;  3BLJ A;  5ADS A;  5FPG A;  3KJD A;  4BUI A;  5AKU A;  3MHJ A;  3KCZ A;  1PAX A;  2RCW A;  4L34 A;  4ZZZ A;  4KZL A;  4HLK A;  4L0T A;  5ECE A;  4F1L A;  4L2G A;  4UVV A;  4PML A;  4ZZY A;  4HLM A;  4OA7 A;  4UI7 A;  4UVO A;  4J3M A;  4K4F A;  3U9Y A;  4L2K A;  4UI4 A;  4UVP A;  4L2F A;  4RV6 A;  4PNM A;  4L7O A;  4W5S A;  4BUE A;  4BUV A;  3GEY A;  4TJY A;  4BU8 A;  1UK1 A;  4UX4 A;  4HLF A;  4J1Z A;  2PAX A;  4TK0 A;  5LXP A;  1UK0 A;  3UH4 A;  4UVZ A;  4HHY A;  4J3L A;  4X52 A;  3P0P A;  5FPF A;  5AL2 A;  4BUD A;  5C5P A;  4TKG A;  4DVI A;  3HKV A;  4MT9 A;  4PNL A;  4L7U A;  4GV7 A;  4R5W A;  3L3L A;  5AEH A;  4UI5 A;  4UVL A;  4N4V A;  1WOK A;  4I9I A;  2X5Y A;  4XHU A;  3GN7 A;  4UVY A;  5AL3 A;  4UVU A;  4BUU A;  5LYH A;  3SMI A;  4BU9 A;  3UH2 A;  5C5R A;  2RF5 A;  5ADQ A;  4HKK A;  5DCZ A;  4BJC A;  4L7P A;  2PAW A;  3P0Q A;  4GV4 A;  4TOR A;  4R6E A;  4KRS A;  4L10 A;  4UW1 A;  4BUF A;  4GV0 A;  5LX6 A;  4BU3 A;  4L7N A;  4BUW A;  1A26 A;  3SE2 A;  4BFP A;  4PAX A;  4L09 A;  4BU6 A;  4BUS A;  3C4H A;  4J21 A;  4PJV A;  4K4E A;  4HKN A;  4BUX A;  4L7L A;  4TJW A;  4BU7 A;  2RD6 A;  4UVW A;  3UA9 A;  3UDD A;  4AVW A;  4BUA A;  4LI7 A;  4UHG A;  5A00 A;  4TKI A;  4HHZ A;  4HMH A;  4TOS A;  5AKW A;  4PY4 A;  3W51 A;  5AL1 A;  4L31 A;  4MSG A;  3FHB A;  3GJW A;  4DQY C;  4GV2 A;  4UVN A;  4W6E A;  4UVT A;  4L0B A;  4HKI A;  3L3M A;  4HL5 A;  4M7B A;  4OQA C;  4N4T A;  3GOY A; 
#chains in the Genus database with same CATH topology
 4KZU A;  4HLH A;  4BS4 A;  4UI3 A;  1YTM A;  4F1Q A;  4IDX A;  5FH1 A;  4L0S A;  3MHK A;  4YWD A;  3KR7 A;  4W5I A;  4BUT A;  4BUY A;  4L70 A;  4BJ9 A;  3MOH A;  4UFU A;  4HYF A;  4OPX C;  4ZZX A;  3KR8 A;  4BUI A;  5AKU A;  3MHJ A;  4KZL A;  4L0T A;  1K3D A;  4F1L A;  4OA7 A;  4WPT A;  4J3M A;  1M51 A;  4UVP A;  4L2F A;  4L7O A;  4W5S A;  4BUE A;  4BUV A;  4HLF A;  4J1Z A;  2PAX A;  1UK0 A;  4UVZ A;  4HHY A;  4TKG A;  4MT9 A;  4PNL A;  5FH3 A;  3L3L A;  2RK8 A;  4UVY A;  5AL3 A;  4R6E A;  4GNP A;  4PAX A;  4J21 A;  1YVY A;  1OS1 A;  3UA9 A;  4LI7 A;  3DTB A;  4GNM A;  4HMH A;  3GJW A;  4GMU A;  3L3M A;  4HL5 A;  4N4T A;  3GOY A;  4XHU A;  4L6Z A;  4UVS A;  4BJB A;  5C5Q A;  1YGG A;  4PNT A;  5FH4 A;  4U6A A;  4MSK A;  3CE0 A;  4UFY A;  4PNN A;  5EBT A;  4L6S A;  1YLH A;  4GMZ A;  2OLQ A;  1GS0 A;  2RKE A;  4UVX A;  4GNQ A;  4UND A;  3DT2 A;  3P0N A;  4BU5 A;  5AL5 A;  3ZL9 A;  5FPG A;  2QZY A;  4ZZZ A;  5ECE A;  2QF2 A;  4UVV A;  4WOU A;  1AYL A;  3U9Y A;  4UI4 A;  2RKD A;  3GEY A;  5LXP A;  3P0P A;  5FPF A;  4OX2 A;  4UVL A;  5ADQ A;  4HKK A;  4BJC A;  4IJS A;  2OLR A;  3P0Q A;  2PY7 X;  4TOR A;  4UW1 A;  5LX6 A;  1OEN A;  4BU3 A;  4BUW A;  3SE2 A;  4L09 A;  5I67 A;  4BU6 A;  1J3B A;  4BUS A;  4PJV A;  4YW8 A;  4BUX A;  4JNG A;  4TJW A;  4UHG A;  4YWB A;  4WPU A;  4L0B A;  2QEW A;  4YW9 A;  2QEY A;  4AVU A;  5ADT A;  3C49 A;  4PJT A;  4UXB A;  3U9H A;  4TVJ A;  4HLG A;  4PNR A;  2ZCI A;  5ADR A;  4TKF A;  5AL4 A;  3DT7 A;  4L0I A;  4GNL A;  5FH5 A;  4J22 A;  4PNQ A;  4WIU A;  4BHH B;  1PAX A;  4IDU B;  1K3C A;  4L34 A;  4HLK A;  4ZZY A;  4UI7 A;  4K4F A;  4WL8 A;  4L2K A;  4RV6 A;  3DT4 A;  1KHE A;  4TJY A;  4BU8 A;  1UK1 A;  4TK0 A;  4J3L A;  4X52 A;  5AL2 A;  5C5P A;  4DVI A;  3HKV A;  4L7U A;  4GV7 A;  4R5W A;  5AEH A;  4I9I A;  2X5Y A;  1KHF A;  3MOF A;  5LYH A;  4J1J A;  4UVU A;  4BU9 A;  2PC9 A;  5C5R A;  2RF5 A;  4L7P A;  2PAW A;  4BUF A;  4GV0 A;  1AQ2 A;  4L7N A;  4BFP A;  3C4H A;  4K4E A;  4HKN A;  3MOE A;  4IDU A;  1KHB A;  4BU7 A;  2RD6 A;  4UVW A;  4BUA A;  2RKA A;  4PY4 A;  3W51 A;  4GV2 A;  4UVN A;  4J1G A;  4HKI A;  4KZQ A;  2QF1 A;  4WIE A;  4LI6 A;  4L33 A;  3PAX A;  4OQB C;  2PQF A;  5ETY A;  4L32 A;  4UI8 A;  4TJU A;  4F0E A;  1EFY A;  3ZLA A;  4PNS A;  4L7R A;  4UUH A;  4GMW A;  4BGP A;  4IUE A;  3SMJ A;  4N3R A;  4UI6 A;  2PXZ X;  4TK5 A;  4LI8 A;  2FAF A;  3BLJ A;  5ADS A;  3KJD A;  2GMV A;  3KCZ A;  2RCW A;  4L2G A;  5FH2 A;  4PML A;  4HLM A;  4UVO A;  2FAH A;  4PNM A;  2RK7 A;  4R43 A;  4UX4 A;  3UH4 A;  4BUD A;  1II2 A;  1XKV A;  4UI5 A;  4N4V A;  1WOK A;  4GNO A;  3GN7 A;  4BUU A;  3SMI A;  3UH2 A;  4RCG A;  4GMM A;  5DCZ A;  4GV4 A;  4KRS A;  4L10 A;  4WPV A;  1A26 A;  4L7L A;  1NHX A;  3UDD A;  4AVW A;  5A00 A;  4TKI A;  4HHZ A;  1KHG A;  4TOS A;  5AKW A;  5AL1 A;  4L31 A;  4MSG A;  3FHB A;  4DQY C;  4W6E A;  5FH0 A;  4UVT A;  4M7B A;  4OQA C;  4L0V A; 
#chains in the Genus database with same CATH homology
 4L6Z A;  2QEW A;  4KZU A;  4UVS A;  4BJB A;  4WIE A;  4HLH A;  4LI6 A;  5C5Q A;  4L33 A;  1YGG A;  4KZQ A;  4YW9 A;  3PAX A;  4BS4 A;  4OQB C;  4UI3 A;  1YTM A;  2PQF A;  2QEY A;  4PNT A;  5ETY A;  5FH4 A;  4L32 A;  4UI8 A;  4AVU A;  4F1Q A;  4TJU A;  4U6A A;  4L0V A;  4MSK A;  3CE0 A;  5ADT A;  4F0E A;  1EFY A;  4UFY A;  4PNN A;  5EBT A;  4L6S A;  4L0S A;  5FH1 A;  3C49 A;  3MHK A;  4YWD A;  1YLH A;  4GMZ A;  4PJT A;  3KR7 A;  4L7R A;  1GS0 A;  4UXB A;  2OLQ A;  4PNS A;  4GMW A;  2RKE A;  4UUH A;  4UVX A;  4W5I A;  3U9H A;  4BUT A;  4BUY A;  4L70 A;  4IUE A;  3SMJ A;  4GNQ A;  4BJ9 A;  4TVJ A;  4HLG A;  4PNR A;  4N3R A;  4UND A;  3DT2 A;  3MOH A;  4UI6 A;  2PXZ X;  3P0N A;  2ZCI A;  4UFU A;  4HYF A;  4BU5 A;  5ADR A;  4TKF A;  4TK5 A;  5AL4 A;  4LI8 A;  3DT7 A;  4L0I A;  4OPX C;  4ZZX A;  4GNL A;  5AL5 A;  5FH5 A;  3KR8 A;  4J22 A;  4PNQ A;  2FAF A;  3BLJ A;  4WIU A;  5ADS A;  5FPG A;  3KJD A;  2GMV A;  4BUI A;  5AKU A;  2QZY A;  3KCZ A;  1PAX A;  3MHJ A;  2RCW A;  1K3C A;  4L34 A;  4ZZZ A;  4KZL A;  4HLK A;  4L0T A;  5ECE A;  1K3D A;  2QF2 A;  4L2G A;  4UVV A;  4PML A;  5FH2 A;  4WOU A;  4ZZY A;  4HLM A;  4OA7 A;  4UI7 A;  1AYL A;  4UVO A;  4J3M A;  4K4F A;  1M51 A;  4WL8 A;  4WPT A;  4L2K A;  4UI4 A;  2RKD A;  4UVP A;  4L2F A;  4RV6 A;  2FAH A;  4PNM A;  3DT4 A;  1KHE A;  4L7O A;  4W5S A;  4BUE A;  2RK7 A;  4BUV A;  3GEY A;  4TJY A;  4F1L A;  4BU8 A;  1UK1 A;  4R43 A;  4UX4 A;  4HLF A;  4J1Z A;  2PAX A;  4TK0 A;  5LXP A;  1UK0 A;  3UH4 A;  4UVZ A;  4HHY A;  4J3L A;  4X52 A;  3P0P A;  5FPF A;  5AL2 A;  4BUD A;  1II2 A;  5C5P A;  4TKG A;  4DVI A;  3HKV A;  4MT9 A;  4PNL A;  4OX2 A;  4L7U A;  4GV7 A;  4R5W A;  5FH3 A;  3L3L A;  1XKV A;  5AEH A;  4UI5 A;  4UVL A;  4N4V A;  1WOK A;  2RK8 A;  4I9I A;  2X5Y A;  4GNO A;  1KHF A;  3GN7 A;  3MOF A;  4UVY A;  4UVU A;  5AL3 A;  4BUU A;  5LYH A;  3SMI A;  4BU9 A;  3UH2 A;  4BUF A;  4RCG A;  4GMM A;  2PC9 A;  4N4T A;  5C5R A;  2RF5 A;  5ADQ A;  4HKK A;  5DCZ A;  4BJC A;  4L7P A;  2PAW A;  2OLR A;  4GV4 A;  2PY7 X;  4R6E A;  3P0Q A;  4KRS A;  4GNP A;  4L10 A;  4GV0 A;  4TOR A;  1OEN A;  4UW1 A;  5LX6 A;  4WPV A;  4BU3 A;  1AQ2 A;  4L7N A;  4BUW A;  1A26 A;  3SE2 A;  3GOY A;  4BFP A;  4PAX A;  4L09 A;  5I67 A;  4BU6 A;  1J3B A;  4BUS A;  3C4H A;  4J21 A;  4PJV A;  4K4E A;  1YVY A;  4HKN A;  3MOE A;  4YW8 A;  4BUX A;  4L7L A;  1KHB A;  1OS1 A;  4TJW A;  4BU7 A;  2RD6 A;  1NHX A;  4UVW A;  3UDD A;  3U9Y A;  3UA9 A;  4AVW A;  4BUA A;  4LI7 A;  2RKA A;  4UHG A;  5A00 A;  4YWB A;  4TKI A;  3DTB A;  4WPU A;  4HHZ A;  1KHG A;  4GNM A;  4HMH A;  4TOS A;  5AKW A;  4PY4 A;  3W51 A;  5AL1 A;  4L31 A;  4MSG A;  3FHB A;  3GJW A;  4DQY C;  4GV2 A;  4UVN A;  4GMU A;  4W6E A;  5FH0 A;  4UVT A;  4L0B A;  4HKI A;  3L3M A;  4HL5 A;  4M7B A;  4OQA C;  2QF1 A;  4XHU A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3L3LA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations