4HHY | Genus

Total Genus 106

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	106
sequence length	349
structure length	349
Chain Sequence	KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 349 atoms

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349 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/transferase inhibitor
source organism	Homo sapiens
publication title	Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors. pubmed doi rcsb
molecule keywords	Poly [ADP-ribose] polymerase 1
total genus	106
structure length	349
sequence length	349
chains with identical sequence	B, C, D
ec nomenclature	ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date	2012-10-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00644	PARP	Poly(ADP-ribose) polymerase catalytic domain
A	PF02877	PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.142.10	Mainly Alpha	Up-down Bundle	Poly(ADP-ribose) Polymerase; domain 1	Poly(ADP-ribose) polymerase, regulatory domain	4hhyA01
3.90.228.10	Alpha Beta	Alpha-Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 3	Phosphoenolpyruvate Carboxykinase; domain 3	4hhyA02

4J3MA 4UVWA 4R6EA 4L34A 5AL5A 4K4EA 4UI4A 4HLGA 4UVTA 4UNDA 4PMLA 4L70A 4L0BA 5ECEA 4UXBA 4LI8A 4L0IA 4L7LA 4UVSA 5EBTA 4UVLA 4PNLA 4BUSA 4L6SA 3KR8A 4N4VA 4W5IA 4UFUA 4J21A 4N3RA 4UVNA 4UX4A 4BS4A 4BU9A 5ADTA 4BUVA 4UI5A 1WOKA 4OQAC 4HLHA 3GJWA 4GV2A 4LI6A 4M7BA 4U6AA 4UUHA 4BJCA 3SMIA 4BU3A 4L0SA 1A26A 5AEHA 4W5SA 4RV6A 4L7RA 4J3LA 4L2FA 4L6ZA 5AKWA 4L0VA 4PNTA 4UI6A 4HKIA 4KRSA 4UVPA 4UW1A 5ETYA 4BUYA 2RD6A 3P0QA 4BUUA 4BUWA 4UVYA 4OA7A 3SE2A 5ADQA 4HL5A 2X5YA 4PY4A 4ZZYA 3UA9A 4HKNA 4L7OA 4L2KA 4TORA 2PAXA 3BLJA 4KZUA 4BU8A 3W51A 3SMJA 4L33A 4XHUA 4MT9A 4TJUA 5LYHA 4TJWA 5AL4A 4N4TA 4PJTA 4HLKA 4TJYA 4X52A 3KR7A 5C5QA 4UVVA 3MHKA 5LX6A 4TK0A 4UHGA 4UVXA 4F1QA 2RCWA 4IUEA 1UK1A 4TKGA 4KZQA 3UDDA 5A00A 4PAXA 3FHBA 4ZZZA 4TOSA 4PNRA 4AVUA 4BJBA 5ADRA 5AL3A 4L7NA 1UK0A 4F0EA 4TKIA 4F1LA 4BFPA 3KCZA 4L7PA 4UI7A 4L31A 3L3LA 4BUAA 3GEYA 5ADSA 4HHYA 4L0TA 4HMHA 4TK5A 4J22A 4TVJA 4MSGA 4TKFA 4OPXC 4J1ZA 4UI8A 5FPGA 5C5RA 5DCZA 4BU7A 4BUEA 4BUXA 4MSKA 4BUDA 3GOYA 3GN7A 4BUFA 2RF5A 4GV4A 4HLFA 5LXPA 4PNMA 4GV0A 4ZZXA 4GV7A 3P0PA 4I9IA 4DVIA 4R5WA 4W6EA 4BU5A 1EFYA 4LI7A 5C5PA 4UVZA 3C49A 3MHJA 3P0NA 3UH2A 4BUIA 4BUTA 3CE0A 3L3MA 4L7UA 4UI3A 1PAXA 4UFYA 4KZLA 4BJ9A 4UVUA 3KJDA 5FPFA 4L32A 4K4FA 4L09A 5AL1A 4PNQA 4UVOA 3U9YA 1GS0A 3UH4A 4BU6A 4DQYC 4HYFA 4OQBC 4PNSA 4PJVA 5AKUA 5AL2A 4HKKA 4HLMA 2PAWA 4L10A 4PNNA 3HKVA 4HHZA 2PQFA 3PAXA 3C4HA 4AVWA 4L2GA 3U9HA
chains in the Genus database with same CATH superfamily

4J3MA 4L34A 4UI4A 4UVTA 4L70A 1KHEA 5ECEA 2QF2A 4UVLA 4L6SA 3KR8A 4W5IA 4UFUA 4N3RA 4BUVA 3GJWA 4GV2A 4UUHA 4BJCA 4L0SA 4W5SA 5FH5A 2GMVA 5FH0A 2QF1A 4UVYA 3SE2A 5ADQA 4PY4A 4L7OA 4YW8A 3W51A 4L33A 4XHUA 5AL4A 4N4TA 4PJTA 4TJYA 2OLQA 3MHKA 4UHGA 2RCWA 4GMZA 3FHBA 4J1GA 5AL3A 1UK0A 3KCZA 4YWBA 4UI7A 5ADSA 4JNGA 3MOFA 3ZLAA 4TVJA 4TKFA 4UI8A 4BUXA 4GNPA 3GN7A 1II2A 4GV0A 4ZZXA 2PXZX 1EFYA 4J1JA 3MHJA 3L3MA 1PAXA 4UFYA 3KJDA 4L09A 4BHHB 4UVOA 4BU6A 4HYFA 4OQBC 5FH2A 4HKKA 2PAWA 3HKVA 3PAXA 4AVWA 4K4EA 3MOEA 2RKEA 2QZYA 1YGGA 4GNLA 4WIUA 4L7LA 4UVSA 2QEYA 4BUSA 4IDUB 4N4VA 4UVNA 4LI6A 4U6AA 4WOUA 4L2FA 4HKIA 4UW1A 1K3CA 3P0QA 2X5YA 2PAXA 4BU8A 4HLKA 4UVVA 4TK0A 4F1QA 4IUEA 4KZQA 4GNMA 5A00A 1YTMA 4TOSA 4BJBA 4L7NA 4TKIA 4F1LA 4L7PA 4BUAA 3GEYA 4HMHA 4TK5A 4GMWA 4MSGA 4J1ZA 5DCZA 4BU7A 4BUDA 2RF5A 3ZL9A 4PNMA 4DVIA 4BU5A 5C5PA 3P0NA 3UH2A 4UVUA 4K4FA 1GS0A 5AKUA 5AL2A 4IJSA 4PNNA 3U9HA 4UVWA 4R6EA 2FAHA 2ZCIA 4HLGA 1AQ2A 4LI8A 4L0IA 5EBTA 4J21A 4UX4A 4RCGA 4BU9A 1K3DA 4OQAC 2FAFA 1A26A 1YLHA 1KHGA 2QEWA 4L6ZA 5AKWA 4UI6A 4BGPA 4UVPA 4BUYA 4BUUA 2OLRA 4BUWA 4OA7A 3DT4A 4TORA 3BLJA 4WPTA 3KR7A 5C5QA 2PY7X 4UVXA 3UDDA 4PAXA 4ZZZA 4PNRA 5FPGA 5C5RA 4BUEA 4MSKA 1OS1A 4BUFA 4GV4A 5LXPA 1NHXA 2RKAA 4YW9A 4R5WA 1YVYA 4W6EA 4BUIA 4BUTA 4WPVA 4WIEA 4BJ9A 5FPFA 4PNQA 3U9YA 2RK8A 4WL8A 4PNSA 4PJVA 1AYLA 4HLMA 4IDXA 4L10A 4OX2A 3MOHA 3C4HA 1M51A 4UVZA 4L2GA 4IDUA 5AL5A 4UNDA 4PMLA 4L0BA 1OENA 4UXBA 4PNLA 4BS4A 5ADTA 4UI5A 1WOKA 4HLHA 4M7BA 4YWDA 3SMIA 3DT2A 4BU3A 5AEHA 4RV6A 4L7RA 4J3LA 4L0VA 3DTBA 4PNTA 4KRSA 5ETYA 2RD6A 4HL5A 4ZZYA 3UA9A 4HKNA 4GNOA 4L2KA 4KZUA 3DT7A 3SMJA 4MT9A 4TJUA 5LYHA 4TJWA 2PC9A 4X52A 5LX6A 5FH3A 1UK1A 4TKGA 4GMMA 4GMUA 2RK7A 4AVUA 5ADRA 4F0EA 4GNQA 5FH4A 4BFPA 4L31A 3L3LA 4HHYA 4L0TA 4J22A 4OPXC 3GOYA 4HLFA 5I67A 3P0PA 4GV7A 4I9IA 1KHBA 4LI7A 3C49A 1J3BA 3CE0A 4L7UA 4UI3A 4KZLA 4L32A 5AL1A 2RKDA 5FH1A 3UH4A 4WPUA 4DQYC 4R43A 1KHFA 4HHZA 1XKVA 2PQFA
chains in the Genus database with same CATH topology

4J3MA 4UVWA 4R6EA 4L34A 2FAHA 2ZCIA 5AL5A 4K4EA 4UI4A 4HLGA 4UVTA 4UNDA 4PMLA 3MOEA 4L70A 1KHEA 4L0BA 1AQ2A 2RKEA 1OENA 2QZYA 5ECEA 1YGGA 4GNLA 4WIUA 4UXBA 4LI8A 4L0IA 4L7LA 2QF2A 2QEYA 4UVSA 4PNLA 4UVLA 4L6SA 5EBTA 3KR8A 4N4VA 4BUSA 4W5IA 4UFUA 4J21A 4N3RA 4UVNA 4UX4A 4BS4A 4RCGA 4BU9A 5ADTA 1K3DA 4BUVA 4UI5A 1WOKA 4OQAC 2FAFA 4HLHA 3GJWA 4GV2A 4LI6A 4M7BA 4U6AA 4UUHA 4YWDA 4BJCA 3SMIA 3DT2A 4L0SA 4BU3A 1A26A 1YLHA 4W5SA 4WOUA 5AEHA 1KHGA 4RV6A 4L7RA 4J3LA 4L2FA 2QEWA 4L6ZA 5AKWA 4L0VA 5FH5A 3DTBA 2GMVA 4PNTA 4UI6A 4HKIA 4KRSA 4UVPA 4UW1A 5ETYA 4BUYA 5FH0A 2RD6A 1K3CA 2QF1A 3P0QA 4BUUA 2OLRA 4BUWA 4UVYA 4OA7A 3SE2A 5ADQA 4HL5A 2X5YA 4PY4A 4ZZYA 3UA9A 4HKNA 3DT4A 4GNOA 4L7OA 4L2KA 4TORA 2PAXA 4YW8A 3BLJA 4KZUA 4BU8A 3DT7A 3W51A 3SMJA 4L33A 4XHUA 4MT9A 4TJUA 4WPTA 4TJWA 5LYHA 5AL4A 4N4TA 2PC9A 4PJTA 4HLKA 4TJYA 4X52A 2OLQA 3KR7A 4UVVA 2PY7X 3MHKA 5C5QA 4TK0A 5LX6A 4UHGA 4UVXA 4F1QA 5FH3A 2RCWA 4IUEA 1UK1A 4GMZA 4TKGA 4KZQA 3UDDA 4GMMA 4GNMA 5A00A 4PAXA 1YTMA 3FHBA 2RK7A 4GMUA 4ZZZA 4TOSA 4PNRA 4AVUA 4BJBA 5ADRA 5AL3A 4L7NA 1UK0A 4F0EA 4GNQA 4TKIA 5FH4A 4F1LA 4BFPA 3KCZA 4YWBA 4L7PA 4UI7A 4L31A 3L3LA 4BUAA 3GEYA 5ADSA 4HHYA 4L0TA 4HMHA 4TK5A 3MOFA 4GMWA 4J22A 4TVJA 4MSGA 4TKFA 4OPXC 4J1ZA 4UI8A 5FPGA 5C5RA 5DCZA 4BU7A 4BUEA 4BUXA 4MSKA 1OS1A 3GOYA 3GN7A 4GNPA 4BUDA 2RF5A 4GV4A 4BUFA 1II2A 4HLFA 5I67A 4PNMA 5LXPA 4GV0A 4ZZXA 4GV7A 1NHXA 3P0PA 4I9IA 2RKAA 4YW9A 4DVIA 4R5WA 1YVYA 2PXZX 4W6EA 4BU5A 1KHBA 1EFYA 4LI7A 5C5PA 4UVZA 3C49A 3MHJA 3P0NA 1J3BA 3UH2A 4BUIA 4WPVA 4BUTA 3CE0A 3L3MA 4L7UA 4WIEA 4UI3A 1PAXA 4UFYA 4KZLA 4BJ9A 4UVUA 3KJDA 5FPFA 4L32A 4K4FA 4L09A 5AL1A 4PNQA 4UVOA 2RKDA 2RK8A 3U9YA 1GS0A 5FH1A 4WL8A 3UH4A 4WPUA 4BU6A 4DQYC 4HYFA 4OQBC 4PNSA 4R43A 4PJVA 1AYLA 5AKUA 5AL2A 5FH2A 4HKKA 4HLMA 2PAWA 1KHFA 4L10A 4PNNA 3HKVA 4OX2A 4HHZA 1XKVA 2PQFA 3MOHA 3PAXA 3C4HA 4AVWA 1M51A 4L2GA 3U9HA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4J3M A;  4UVW A;  4R6E A;  4L34 A;  5AL5 A;  4K4E A;  4UI4 A;  4HLG A;  4UVT A;  4UND A;  4PML A;  4L70 A;  4L0B A;  5ECE A;  4UXB A;  4LI8 A;  4L0I A;  4L7L A;  4UVS A;  5EBT A;  4UVL A;  4PNL A;  4BUS A;  4L6S A;  3KR8 A;  4N4V A;  4W5I A;  4UFU A;  4J21 A;  4N3R A;  4UVN A;  4UX4 A;  4BS4 A;  4BU9 A;  5ADT A;  4BUV A;  4UI5 A;  1WOK A;  4OQA C;  4HLH A;  3GJW A;  4GV2 A;  4LI6 A;  4M7B A;  4U6A A;  4UUH A;  4BJC A;  3SMI A;  4BU3 A;  4L0S A;  1A26 A;  5AEH A;  4W5S A;  4RV6 A;  4L7R A;  4J3L A;  4L2F A;  4L6Z A;  5AKW A;  4L0V A;  4PNT A;  4UI6 A;  4HKI A;  4KRS A;  4UVP A;  4UW1 A;  5ETY A;  4BUY A;  2RD6 A;  3P0Q A;  4BUU A;  4BUW A;  4UVY A;  4OA7 A;  3SE2 A;  5ADQ A;  4HL5 A;  2X5Y A;  4PY4 A;  4ZZY A;  3UA9 A;  4HKN A;  4L7O A;  4L2K A;  4TOR A;  2PAX A;  3BLJ A;  4KZU A;  4BU8 A;  3W51 A;  3SMJ A;  4L33 A;  4XHU A;  4MT9 A;  4TJU A;  5LYH A;  4TJW A;  5AL4 A;  4N4T A;  4PJT A;  4HLK A;  4TJY A;  4X52 A;  3KR7 A;  5C5Q A;  4UVV A;  3MHK A;  5LX6 A;  4TK0 A;  4UHG A;  4UVX A;  4F1Q A;  2RCW A;  4IUE A;  1UK1 A;  4TKG A;  4KZQ A;  3UDD A;  5A00 A;  4PAX A;  3FHB A;  4ZZZ A;  4TOS A;  4PNR A;  4AVU A;  4BJB A;  5ADR A;  5AL3 A;  4L7N A;  1UK0 A;  4F0E A;  4TKI A;  4F1L A;  4BFP A;  3KCZ A;  4L7P A;  4UI7 A;  4L31 A;  3L3L A;  4BUA A;  3GEY A;  5ADS A;  4HHY A;  4L0T A;  4HMH A;  4TK5 A;  4J22 A;  4TVJ A;  4MSG A;  4TKF A;  4OPX C;  4J1Z A;  4UI8 A;  5FPG A;  5C5R A;  5DCZ A;  4BU7 A;  4BUE A;  4BUX A;  4MSK A;  4BUD A;  3GOY A;  3GN7 A;  4BUF A;  2RF5 A;  4GV4 A;  4HLF A;  5LXP A;  4PNM A;  4GV0 A;  4ZZX A;  4GV7 A;  3P0P A;  4I9I A;  4DVI A;  4R5W A;  4W6E A;  4BU5 A;  1EFY A;  4LI7 A;  5C5P A;  4UVZ A;  3C49 A;  3MHJ A;  3P0N A;  3UH2 A;  4BUI A;  4BUT A;  3CE0 A;  3L3M A;  4L7U A;  4UI3 A;  1PAX A;  4UFY A;  4KZL A;  4BJ9 A;  4UVU A;  3KJD A;  5FPF A;  4L32 A;  4K4F A;  4L09 A;  5AL1 A;  4PNQ A;  4UVO A;  3U9Y A;  1GS0 A;  3UH4 A;  4BU6 A;  4DQY C;  4HYF A;  4OQB C;  4PNS A;  4PJV A;  5AKU A;  5AL2 A;  4HKK A;  4HLM A;  2PAW A;  4L10 A;  4PNN A;  3HKV A;  4HHZ A;  2PQF A;  3PAX A;  3C4H A;  4AVW A;  4L2G A;  3U9H A; 
#chains in the Genus database with same CATH topology
 4J3M A;  4L34 A;  4UI4 A;  4UVT A;  4L70 A;  1KHE A;  5ECE A;  2QF2 A;  4UVL A;  4L6S A;  3KR8 A;  4W5I A;  4UFU A;  4N3R A;  4BUV A;  3GJW A;  4GV2 A;  4UUH A;  4BJC A;  4L0S A;  4W5S A;  5FH5 A;  2GMV A;  5FH0 A;  2QF1 A;  4UVY A;  3SE2 A;  5ADQ A;  4PY4 A;  4L7O A;  4YW8 A;  3W51 A;  4L33 A;  4XHU A;  5AL4 A;  4N4T A;  4PJT A;  4TJY A;  2OLQ A;  3MHK A;  4UHG A;  2RCW A;  4GMZ A;  3FHB A;  4J1G A;  5AL3 A;  1UK0 A;  3KCZ A;  4YWB A;  4UI7 A;  5ADS A;  4JNG A;  3MOF A;  3ZLA A;  4TVJ A;  4TKF A;  4UI8 A;  4BUX A;  4GNP A;  3GN7 A;  1II2 A;  4GV0 A;  4ZZX A;  2PXZ X;  1EFY A;  4J1J A;  3MHJ A;  3L3M A;  1PAX A;  4UFY A;  3KJD A;  4L09 A;  4BHH B;  4UVO A;  4BU6 A;  4HYF A;  4OQB C;  5FH2 A;  4HKK A;  2PAW A;  3HKV A;  3PAX A;  4AVW A;  4K4E A;  3MOE A;  2RKE A;  2QZY A;  1YGG A;  4GNL A;  4WIU A;  4L7L A;  4UVS A;  2QEY A;  4BUS A;  4IDU B;  4N4V A;  4UVN A;  4LI6 A;  4U6A A;  4WOU A;  4L2F A;  4HKI A;  4UW1 A;  1K3C A;  3P0Q A;  2X5Y A;  2PAX A;  4BU8 A;  4HLK A;  4UVV A;  4TK0 A;  4F1Q A;  4IUE A;  4KZQ A;  4GNM A;  5A00 A;  1YTM A;  4TOS A;  4BJB A;  4L7N A;  4TKI A;  4F1L A;  4L7P A;  4BUA A;  3GEY A;  4HMH A;  4TK5 A;  4GMW A;  4MSG A;  4J1Z A;  5DCZ A;  4BU7 A;  4BUD A;  2RF5 A;  3ZL9 A;  4PNM A;  4DVI A;  4BU5 A;  5C5P A;  3P0N A;  3UH2 A;  4UVU A;  4K4F A;  1GS0 A;  5AKU A;  5AL2 A;  4IJS A;  4PNN A;  3U9H A;  4UVW A;  4R6E A;  2FAH A;  2ZCI A;  4HLG A;  1AQ2 A;  4LI8 A;  4L0I A;  5EBT A;  4J21 A;  4UX4 A;  4RCG A;  4BU9 A;  1K3D A;  4OQA C;  2FAF A;  1A26 A;  1YLH A;  1KHG A;  2QEW A;  4L6Z A;  5AKW A;  4UI6 A;  4BGP A;  4UVP A;  4BUY A;  4BUU A;  2OLR A;  4BUW A;  4OA7 A;  3DT4 A;  4TOR A;  3BLJ A;  4WPT A;  3KR7 A;  5C5Q A;  2PY7 X;  4UVX A;  3UDD A;  4PAX A;  4ZZZ A;  4PNR A;  5FPG A;  5C5R A;  4BUE A;  4MSK A;  1OS1 A;  4BUF A;  4GV4 A;  5LXP A;  1NHX A;  2RKA A;  4YW9 A;  4R5W A;  1YVY A;  4W6E A;  4BUI A;  4BUT A;  4WPV A;  4WIE A;  4BJ9 A;  5FPF A;  4PNQ A;  3U9Y A;  2RK8 A;  4WL8 A;  4PNS A;  4PJV A;  1AYL A;  4HLM A;  4IDX A;  4L10 A;  4OX2 A;  3MOH A;  3C4H A;  1M51 A;  4UVZ A;  4L2G A;  4IDU A;  5AL5 A;  4UND A;  4PML A;  4L0B A;  1OEN A;  4UXB A;  4PNL A;  4BS4 A;  5ADT A;  4UI5 A;  1WOK A;  4HLH A;  4M7B A;  4YWD A;  3SMI A;  3DT2 A;  4BU3 A;  5AEH A;  4RV6 A;  4L7R A;  4J3L A;  4L0V A;  3DTB A;  4PNT A;  4KRS A;  5ETY A;  2RD6 A;  4HL5 A;  4ZZY A;  3UA9 A;  4HKN A;  4GNO A;  4L2K A;  4KZU A;  3DT7 A;  3SMJ A;  4MT9 A;  4TJU A;  5LYH A;  4TJW A;  2PC9 A;  4X52 A;  5LX6 A;  5FH3 A;  1UK1 A;  4TKG A;  4GMM A;  4GMU A;  2RK7 A;  4AVU A;  5ADR A;  4F0E A;  4GNQ A;  5FH4 A;  4BFP A;  4L31 A;  3L3L A;  4HHY A;  4L0T A;  4J22 A;  4OPX C;  3GOY A;  4HLF A;  5I67 A;  3P0P A;  4GV7 A;  4I9I A;  1KHB A;  4LI7 A;  3C49 A;  1J3B A;  3CE0 A;  4L7U A;  4UI3 A;  4KZL A;  4L32 A;  5AL1 A;  2RKD A;  5FH1 A;  3UH4 A;  4WPU A;  4DQY C;  4R43 A;  1KHF A;  4HHZ A;  1XKV A;  2PQF A; 
#chains in the Genus database with same CATH homology
 4J3M A;  4UVW A;  4R6E A;  4L34 A;  2FAH A;  2ZCI A;  5AL5 A;  4K4E A;  4UI4 A;  4HLG A;  4UVT A;  4UND A;  4PML A;  3MOE A;  4L70 A;  1KHE A;  4L0B A;  1AQ2 A;  2RKE A;  1OEN A;  2QZY A;  5ECE A;  1YGG A;  4GNL A;  4WIU A;  4UXB A;  4LI8 A;  4L0I A;  4L7L A;  2QF2 A;  2QEY A;  4UVS A;  4PNL A;  4UVL A;  4L6S A;  5EBT A;  3KR8 A;  4N4V A;  4BUS A;  4W5I A;  4UFU A;  4J21 A;  4N3R A;  4UVN A;  4UX4 A;  4BS4 A;  4RCG A;  4BU9 A;  5ADT A;  1K3D A;  4BUV A;  4UI5 A;  1WOK A;  4OQA C;  2FAF A;  4HLH A;  3GJW A;  4GV2 A;  4LI6 A;  4M7B A;  4U6A A;  4UUH A;  4YWD A;  4BJC A;  3SMI A;  3DT2 A;  4L0S A;  4BU3 A;  1A26 A;  1YLH A;  4W5S A;  4WOU A;  5AEH A;  1KHG A;  4RV6 A;  4L7R A;  4J3L A;  4L2F A;  2QEW A;  4L6Z A;  5AKW A;  4L0V A;  5FH5 A;  3DTB A;  2GMV A;  4PNT A;  4UI6 A;  4HKI A;  4KRS A;  4UVP A;  4UW1 A;  5ETY A;  4BUY A;  5FH0 A;  2RD6 A;  1K3C A;  2QF1 A;  3P0Q A;  4BUU A;  2OLR A;  4BUW A;  4UVY A;  4OA7 A;  3SE2 A;  5ADQ A;  4HL5 A;  2X5Y A;  4PY4 A;  4ZZY A;  3UA9 A;  4HKN A;  3DT4 A;  4GNO A;  4L7O A;  4L2K A;  4TOR A;  2PAX A;  4YW8 A;  3BLJ A;  4KZU A;  4BU8 A;  3DT7 A;  3W51 A;  3SMJ A;  4L33 A;  4XHU A;  4MT9 A;  4TJU A;  4WPT A;  4TJW A;  5LYH A;  5AL4 A;  4N4T A;  2PC9 A;  4PJT A;  4HLK A;  4TJY A;  4X52 A;  2OLQ A;  3KR7 A;  4UVV A;  2PY7 X;  3MHK A;  5C5Q A;  4TK0 A;  5LX6 A;  4UHG A;  4UVX A;  4F1Q A;  5FH3 A;  2RCW A;  4IUE A;  1UK1 A;  4GMZ A;  4TKG A;  4KZQ A;  3UDD A;  4GMM A;  4GNM A;  5A00 A;  4PAX A;  1YTM A;  3FHB A;  2RK7 A;  4GMU A;  4ZZZ A;  4TOS A;  4PNR A;  4AVU A;  4BJB A;  5ADR A;  5AL3 A;  4L7N A;  1UK0 A;  4F0E A;  4GNQ A;  4TKI A;  5FH4 A;  4F1L A;  4BFP A;  3KCZ A;  4YWB A;  4L7P A;  4UI7 A;  4L31 A;  3L3L A;  4BUA A;  3GEY A;  5ADS A;  4HHY A;  4L0T A;  4HMH A;  4TK5 A;  3MOF A;  4GMW A;  4J22 A;  4TVJ A;  4MSG A;  4TKF A;  4OPX C;  4J1Z A;  4UI8 A;  5FPG A;  5C5R A;  5DCZ A;  4BU7 A;  4BUE A;  4BUX A;  4MSK A;  1OS1 A;  3GOY A;  3GN7 A;  4GNP A;  4BUD A;  2RF5 A;  4GV4 A;  4BUF A;  1II2 A;  4HLF A;  5I67 A;  4PNM A;  5LXP A;  4GV0 A;  4ZZX A;  4GV7 A;  1NHX A;  3P0P A;  4I9I A;  2RKA A;  4YW9 A;  4DVI A;  4R5W A;  1YVY A;  2PXZ X;  4W6E A;  4BU5 A;  1KHB A;  1EFY A;  4LI7 A;  5C5P A;  4UVZ A;  3C49 A;  3MHJ A;  3P0N A;  1J3B A;  3UH2 A;  4BUI A;  4WPV A;  4BUT A;  3CE0 A;  3L3M A;  4L7U A;  4WIE A;  4UI3 A;  1PAX A;  4UFY A;  4KZL A;  4BJ9 A;  4UVU A;  3KJD A;  5FPF A;  4L32 A;  4K4F A;  4L09 A;  5AL1 A;  4PNQ A;  4UVO A;  2RKD A;  2RK8 A;  3U9Y A;  1GS0 A;  5FH1 A;  4WL8 A;  3UH4 A;  4WPU A;  4BU6 A;  4DQY C;  4HYF A;  4OQB C;  4PNS A;  4R43 A;  4PJV A;  1AYL A;  5AKU A;  5AL2 A;  5FH2 A;  4HKK A;  4HLM A;  2PAW A;  1KHF A;  4L10 A;  4PNN A;  3HKV A;  4OX2 A;  4HHZ A;  1XKV A;  2PQF A;  3MOH A;  3PAX A;  3C4H A;  4AVW A;  1M51 A;  4L2G A;  3U9H A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4HHYA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations