4L6S | Genus

Total Genus 110

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	110
sequence length	352
structure length	351
Chain Sequence	HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 351 atoms

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351 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transferase/transferase inhibitor
source organism	Homo sapiens
publication title	Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitors pubmed doi rcsb
molecule keywords	Poly [ADP-ribose] polymerase 1
total genus	110
structure length	351
sequence length	352
chains with identical sequence	B
ec nomenclature	ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date	2013-06-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00644	PARP	Poly(ADP-ribose) polymerase catalytic domain
A	PF02877	PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.142.10	Mainly Alpha	Up-down Bundle	Poly(ADP-ribose) Polymerase; domain 1	Poly(ADP-ribose) polymerase, regulatory domain	4l6sA01
3.90.228.10	Alpha Beta	Alpha-Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 3	Phosphoenolpyruvate Carboxykinase; domain 3	4l6sA02

4HLGA 4R6EA 4HHYA 5LXPA 4XHUA 4KZUA 3GJWA 4OQAC 5DCZA 4L7OA 4L0IA 4HLHA 3P0NA 2RD6A 2PQFA 4HKKA 4UI7A 3U9YA 1UK0A 4J21A 5AKWA 4BFPA 4IUEA 5ETYA 4BU5A 5AEHA 4HYFA 4UFUA 4PNSA 4BUTA 4DVIA 4UX4A 4GV7A 5ECEA 4UVXA 3KJDA 4L70A 4UVZA 4TK5A 4PAXA 4TJUA 3GOYA 4TOSA 4BUSA 4GV0A 4L33A 4BJ9A 3UA9A 4BJBA 4PY4A 5ADQA 4BUVA 5ADTA 4UFYA 5AL5A 2PAWA 4L6SA 3KR8A 4KZLA 4KZQA 4N4TA 3P0PA 3SE2A 4OPXC 4BU6A 4MSGA 4UI8A 4TORA 2RCWA 4L2GA 4BUAA 1UK1A 4L2KA 3SMIA 5FPFA 3BLJA 4L0BA 4BU3A 4L31A 4F0EA 4GV4A 4UVYA 4L10A 4UI6A 4L2FA 4UXBA 4OQBC 4TKIA 4TJWA 4J22A 4BS4A 4AVWA 4GV2A 4PNTA 4BUXA 4K4EA 3W51A 4BU9A 4UVSA 4ZZZA 4LI8A 3PAXA 1GS0A 4L7RA 4PNMA 4MT9A 3KR7A 2RF5A 4DQYC 4L0TA 4UVNA 4UW1A 3MHKA 4ZZXA 4PNQA 4L7LA 4U6AA 4LI6A 4UI4A 4M7BA 4N3RA 4TVJA 3GN7A 1A26A 4UVTA 4HHZA 4KRSA 5LX6A 4L7NA 3P0QA 4I9IA 4L34A 4OA7A 4L09A 3UDDA 4BUFA 5ADRA 5ADSA 4PNRA 4X52A 4PNNA 5AKUA 4RV6A 4BUUA 4BUWA 4UI3A 4BUYA 3U9HA 4BUIA 2PAXA 4HLKA 4UUHA 4UNDA 3UH2A 3HKVA 3L3LA 4L32A 4PJTA 4HLFA 4UI5A 4L7UA 5AL1A 3CE0A 4L7PA 5A00A 4PMLA 5AL3A 4J3MA 5C5PA 3FHBA 4TK0A 4BUEA 4W5IA 4UVLA 4AVUA 4BU8A 4TJYA 5C5RA 4HL5A 4UHGA 5AL2A 5C5QA 3GEYA 1WOKA 4L0VA 3MHJA 4HMHA 4PNLA 4TKGA 4BU7A 4J1ZA 4HKIA 1EFYA 4LI7A 4TKFA 3SMJA 4R5WA 4UVOA 4HKNA 4UVVA 5LYHA 1PAXA 3L3MA 3UH4A 4J3LA 3C49A 4UVUA 4W6EA 4F1LA 5FPGA 4UVPA 4K4FA 3KCZA 4F1QA 4UVWA 4BJCA 4BUDA 4N4VA 4W5SA 4L6ZA 4PJVA 4ZZYA 4MSKA 5AL4A 3C4HA 5EBTA 2X5YA 4HLMA 4L0SA
chains in the Genus database with same CATH superfamily

4HHYA 4XHUA 4L0IA 1YTMA 4UI7A 4IDUA 2PQFA 4WPTA 2PY7X 4BU5A 4HYFA 3DT7A 2QZYA 4BUVA 3KR8A 4OPXC 4WL8A 2RCWA 4BUAA 4L2KA 3SMIA 5FPFA 5FH1A 4GMWA 4L10A 4UXBA 4BGPA 4OQBC 4R43A 2OLRA 4TJWA 4J22A 4GV2A 4PNTA 4BU9A 2RK7A 4L7RA 4MT9A 2RF5A 4UVNA 3MHKA 4ZZXA 2QEYA 4L7LA 4IDXA 1NHXA 4HHZA 4L09A 3UDDA 5ADRA 4PNRA 4BUUA 4RV6A 4UUHA 3HKVA 1YGGA 4WIUA 4OX2A 5A00A 5C5RA 4HL5A 5C5QA 2RKEA 4LI7A 4TKFA 1AQ2A 4HKNA 1PAXA 3L3MA 4F1LA 1YVYA 2GMVA 5FH5A 4N4VA 4IDUB 3C4HA 5EBTA 1OS1A 4J1GA 5LXPA 5DCZA 2OLQA 2RD6A 4RCGA 5AKWA 5ETYA 4UFUA 4BUTA 4YWBA 4DVIA 5ECEA 4YWDA 3MOEA 4L70A 4UVZA 1M51A 4PAXA 4TK5A 3GOYA 4L33A 4BJBA 4J1JA 5AL5A 4L6SA 4KZLA 1XKVA 4N4TA 3P0PA 4MSGA 4BU3A 4L0BA 4GV4A 4UI6A 4TKIA 4BS4A 3PAXA 1GS0A 4UW1A 4JNGA 2QEWA 4M7BA 4N3RA 3GN7A 4GMMA 5LX6A 4BUFA 5AKUA 4BUYA 4BUIA 2PAXA 5C5PA 3CE0A 4GNLA 5AL3A 3FHBA 5FH2A 4W5IA 5AL2A 3GEYA 4L0VA 4HMHA 4BU7A 4J1ZA 2RKDA 5LYHA 3DT2A 4UVVA 5FPGA 5I67A 4YW9A 4UVPA 2PC9A 4K4FA 3KCZA 4BJCA 4L6ZA 2FAFA 5AL4A 4HLMA 4HLGA 4R6EA 4KZUA 4OQAC 4HLHA 2FAHA 3U9YA 1UK0A 4UVXA 3UA9A 4PY4A 4UFYA 3SE2A 2RK8A 4BU6A 4UI8A 1KHFA 4TORA 4L2GA 1KHEA 1KHGA 3BLJA 4IJSA 4L2FA 5FH4A 4AVWA 4WPVA 4ZZZA 4LI8A 1K3DA 4PNMA 3KR7A 4LI6A 4UI4A 4TVJA 4UVTA 4KRSA 4L7NA 3P0QA 4L34A 4OA7A 5ADSA 4GNPA 4X52A 4PNNA 4BUWA 4WOUA 4UI3A 3U9HA 4HLKA 4UNDA 3UH2A 3L3LA 4L32A 4GNQA 4L7UA 5AL1A 4L7PA 2QF2A 3MOHA 4BUEA 4BU8A 4TJYA 4BHHB 3MHJA 4PNLA 4TKGA 4HKIA 3SMJA 4UVOA 4J3LA 3C49A 4UVUA 4W6EA 4UVWA 3ZL9A 4WIEA 4W5SA 1OENA 2PXZX 4ZZYA 2X5YA 4L0SA 3MOFA 5FH3A 3ZLAA 3GJWA 4L7OA 4GNOA 3P0NA 4HKKA 1KHBA 4J21A 4BFPA 4IUEA 5AEHA 4PNSA 4UX4A 4GV7A 4WPUA 3KJDA 4GMZA 4TOSA 4TJUA 4BUSA 4GV0A 4BJ9A 5ADQA 5ADTA 2PAWA 4KZQA 1II2A 1YLHA 1UK1A 1AYLA 4L31A 4F0EA 4UVYA 4BUXA 4K4EA 3W51A 4UVSA 4GMUA 4DQYC 4L0TA 4PNQA 4U6AA 4GNMA 4YW8A 1A26A 3DTBA 4I9IA 5FH0A 3DT4A 4PJTA 4HLFA 4UI5A 4PMLA 4J3MA 4TK0A 1K3CA 4UVLA 4AVUA 4UHGA 2RKAA 1WOKA 2ZCIA 1EFYA 4R5WA 2QF1A 3UH4A 4F1QA 4BUDA 4MSKA 4PJVA 1J3BA
chains in the Genus database with same CATH topology

4HLGA 4R6EA 3MOFA 1OS1A 5FH3A 4HHYA 5LXPA 4XHUA 4KZUA 3GJWA 4OQAC 5DCZA 4L7OA 4L0IA 4HLHA 1YTMA 2FAHA 2RD6A 2OLQA 2PQFA 3P0NA 1KHBA 4GNOA 4HKKA 1UK0A 4UI7A 4J21A 4WPTA 5AKWA 3U9YA 4BFPA 4IUEA 5ETYA 2PY7X 4BU5A 5AEHA 4HYFA 4UFUA 4PNSA 4YWBA 4BUTA 4DVIA 4UX4A 4GV7A 5ECEA 3DT7A 2QZYA 3KJDA 4GMZA 4UVXA 3MOEA 4WPUA 4YWDA 4L70A 4UVZA 1M51A 4PAXA 4TJUA 3GOYA 4TK5A 4TOSA 4GV0A 4L33A 4BUSA 4BJ9A 3UA9A 4BJBA 4PY4A 5ADQA 4BUVA 5ADTA 4UFYA 5AL5A 2PAWA 4L6SA 3KR8A 4KZLA 1XKVA 4KZQA 4N4TA 3P0PA 3SE2A 4OPXC 1II2A 1YLHA 2RK8A 4MSGA 4UI8A 4BU6A 1KHFA 4WL8A 4TORA 2RCWA 4L2GA 4RCGA 1KHEA 4BUAA 1KHGA 1UK1A 4L2KA 3SMIA 5FPFA 3BLJA 4L0BA 5FH1A 1AYLA 4GMWA 4L31A 4BU3A 4GV4A 4F0EA 4UVYA 4L10A 4UI6A 4L2FA 4UXBA 4OQBC 4R43A 4TKIA 2OLRA 4TJWA 5FH4A 4J22A 4BS4A 4AVWA 4GV2A 4PNTA 4WPVA 4K4EA 3W51A 4BU9A 4BUXA 4UVSA 4ZZZA 4LI8A 1K3DA 2RK7A 3PAXA 1GS0A 4GMUA 4L7RA 4PNMA 4MT9A 3KR7A 2RF5A 4DQYC 4L0TA 4UVNA 4UW1A 3MHKA 4ZZXA 2QEYA 4PNQA 4L7LA 2QEWA 4U6AA 4LI6A 4GNMA 4UI4A 4M7BA 4N3RA 5C5PA 4TVJA 4YW8A 3GN7A 4GMMA 1A26A 1NHXA 4HHZA 4KRSA 4UVTA 5LX6A 4L7NA 3P0QA 3DTBA 4I9IA 4L34A 4OA7A 4L09A 3UDDA 5FH0A 4BUFA 5ADRA 5ADSA 4GNPA 4PNRA 4X52A 4PNNA 3DT4A 4RV6A 5AKUA 4BUUA 4BUWA 4WOUA 4UI3A 4BUYA 3U9HA 4BUIA 2PAXA 4HLKA 4UUHA 4UNDA 3UH2A 3HKVA 3L3LA 1YGGA 4L32A 4PJTA 4WIUA 4GNQA 4HLFA 4OX2A 4L7UA 4UI5A 5AL1A 3CE0A 4L7PA 5A00A 2QF2A 4GNLA 4J3MA 4PMLA 5AL3A 3FHBA 1K3CA 3MOHA 5FH2A 4TK0A 4BUEA 4W5IA 4UVLA 4AVUA 4BU8A 4TJYA 5C5RA 4HL5A 2RKAA 4UHGA 5AL2A 5C5QA 3GEYA 1WOKA 2RKEA 3MHJA 4HMHA 4L0VA 4PNLA 4TKGA 2ZCIA 4BU7A 4J1ZA 4HKIA 1EFYA 2RKDA 4LI7A 4TKFA 3SMJA 1AQ2A 4R5WA 4UVOA 4HKNA 3DT2A 4UVVA 5LYHA 1PAXA 2QF1A 3L3MA 3UH4A 4J3LA 3C49A 4UVUA 4W6EA 4F1LA 1YVYA 5FPGA 5I67A 4YW9A 4UVPA 2PC9A 4K4FA 3KCZA 4F1QA 4UVWA 2GMVA 4WIEA 4BJCA 4BUDA 5FH5A 4N4VA 4W5SA 1OENA 2PXZX 4L6ZA 4PJVA 4ZZYA 2FAFA 4MSKA 5AL4A 3C4HA 1J3BA 5EBTA 2X5YA 4HLMA 4L0SA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4HLG A;  4R6E A;  4HHY A;  5LXP A;  4XHU A;  4KZU A;  3GJW A;  4OQA C;  5DCZ A;  4L7O A;  4L0I A;  4HLH A;  3P0N A;  2RD6 A;  2PQF A;  4HKK A;  4UI7 A;  3U9Y A;  1UK0 A;  4J21 A;  5AKW A;  4BFP A;  4IUE A;  5ETY A;  4BU5 A;  5AEH A;  4HYF A;  4UFU A;  4PNS A;  4BUT A;  4DVI A;  4UX4 A;  4GV7 A;  5ECE A;  4UVX A;  3KJD A;  4L70 A;  4UVZ A;  4TK5 A;  4PAX A;  4TJU A;  3GOY A;  4TOS A;  4BUS A;  4GV0 A;  4L33 A;  4BJ9 A;  3UA9 A;  4BJB A;  4PY4 A;  5ADQ A;  4BUV A;  5ADT A;  4UFY A;  5AL5 A;  2PAW A;  4L6S A;  3KR8 A;  4KZL A;  4KZQ A;  4N4T A;  3P0P A;  3SE2 A;  4OPX C;  4BU6 A;  4MSG A;  4UI8 A;  4TOR A;  2RCW A;  4L2G A;  4BUA A;  1UK1 A;  4L2K A;  3SMI A;  5FPF A;  3BLJ A;  4L0B A;  4BU3 A;  4L31 A;  4F0E A;  4GV4 A;  4UVY A;  4L10 A;  4UI6 A;  4L2F A;  4UXB A;  4OQB C;  4TKI A;  4TJW A;  4J22 A;  4BS4 A;  4AVW A;  4GV2 A;  4PNT A;  4BUX A;  4K4E A;  3W51 A;  4BU9 A;  4UVS A;  4ZZZ A;  4LI8 A;  3PAX A;  1GS0 A;  4L7R A;  4PNM A;  4MT9 A;  3KR7 A;  2RF5 A;  4DQY C;  4L0T A;  4UVN A;  4UW1 A;  3MHK A;  4ZZX A;  4PNQ A;  4L7L A;  4U6A A;  4LI6 A;  4UI4 A;  4M7B A;  4N3R A;  4TVJ A;  3GN7 A;  1A26 A;  4UVT A;  4HHZ A;  4KRS A;  5LX6 A;  4L7N A;  3P0Q A;  4I9I A;  4L34 A;  4OA7 A;  4L09 A;  3UDD A;  4BUF A;  5ADR A;  5ADS A;  4PNR A;  4X52 A;  4PNN A;  5AKU A;  4RV6 A;  4BUU A;  4BUW A;  4UI3 A;  4BUY A;  3U9H A;  4BUI A;  2PAX A;  4HLK A;  4UUH A;  4UND A;  3UH2 A;  3HKV A;  3L3L A;  4L32 A;  4PJT A;  4HLF A;  4UI5 A;  4L7U A;  5AL1 A;  3CE0 A;  4L7P A;  5A00 A;  4PML A;  5AL3 A;  4J3M A;  5C5P A;  3FHB A;  4TK0 A;  4BUE A;  4W5I A;  4UVL A;  4AVU A;  4BU8 A;  4TJY A;  5C5R A;  4HL5 A;  4UHG A;  5AL2 A;  5C5Q A;  3GEY A;  1WOK A;  4L0V A;  3MHJ A;  4HMH A;  4PNL A;  4TKG A;  4BU7 A;  4J1Z A;  4HKI A;  1EFY A;  4LI7 A;  4TKF A;  3SMJ A;  4R5W A;  4UVO A;  4HKN A;  4UVV A;  5LYH A;  1PAX A;  3L3M A;  3UH4 A;  4J3L A;  3C49 A;  4UVU A;  4W6E A;  4F1L A;  5FPG A;  4UVP A;  4K4F A;  3KCZ A;  4F1Q A;  4UVW A;  4BJC A;  4BUD A;  4N4V A;  4W5S A;  4L6Z A;  4PJV A;  4ZZY A;  4MSK A;  5AL4 A;  3C4H A;  5EBT A;  2X5Y A;  4HLM A;  4L0S A; 
#chains in the Genus database with same CATH topology
 4HHY A;  4XHU A;  4L0I A;  1YTM A;  4UI7 A;  4IDU A;  2PQF A;  4WPT A;  2PY7 X;  4BU5 A;  4HYF A;  3DT7 A;  2QZY A;  4BUV A;  3KR8 A;  4OPX C;  4WL8 A;  2RCW A;  4BUA A;  4L2K A;  3SMI A;  5FPF A;  5FH1 A;  4GMW A;  4L10 A;  4UXB A;  4BGP A;  4OQB C;  4R43 A;  2OLR A;  4TJW A;  4J22 A;  4GV2 A;  4PNT A;  4BU9 A;  2RK7 A;  4L7R A;  4MT9 A;  2RF5 A;  4UVN A;  3MHK A;  4ZZX A;  2QEY A;  4L7L A;  4IDX A;  1NHX A;  4HHZ A;  4L09 A;  3UDD A;  5ADR A;  4PNR A;  4BUU A;  4RV6 A;  4UUH A;  3HKV A;  1YGG A;  4WIU A;  4OX2 A;  5A00 A;  5C5R A;  4HL5 A;  5C5Q A;  2RKE A;  4LI7 A;  4TKF A;  1AQ2 A;  4HKN A;  1PAX A;  3L3M A;  4F1L A;  1YVY A;  2GMV A;  5FH5 A;  4N4V A;  4IDU B;  3C4H A;  5EBT A;  1OS1 A;  4J1G A;  5LXP A;  5DCZ A;  2OLQ A;  2RD6 A;  4RCG A;  5AKW A;  5ETY A;  4UFU A;  4BUT A;  4YWB A;  4DVI A;  5ECE A;  4YWD A;  3MOE A;  4L70 A;  4UVZ A;  1M51 A;  4PAX A;  4TK5 A;  3GOY A;  4L33 A;  4BJB A;  4J1J A;  5AL5 A;  4L6S A;  4KZL A;  1XKV A;  4N4T A;  3P0P A;  4MSG A;  4BU3 A;  4L0B A;  4GV4 A;  4UI6 A;  4TKI A;  4BS4 A;  3PAX A;  1GS0 A;  4UW1 A;  4JNG A;  2QEW A;  4M7B A;  4N3R A;  3GN7 A;  4GMM A;  5LX6 A;  4BUF A;  5AKU A;  4BUY A;  4BUI A;  2PAX A;  5C5P A;  3CE0 A;  4GNL A;  5AL3 A;  3FHB A;  5FH2 A;  4W5I A;  5AL2 A;  3GEY A;  4L0V A;  4HMH A;  4BU7 A;  4J1Z A;  2RKD A;  5LYH A;  3DT2 A;  4UVV A;  5FPG A;  5I67 A;  4YW9 A;  4UVP A;  2PC9 A;  4K4F A;  3KCZ A;  4BJC A;  4L6Z A;  2FAF A;  5AL4 A;  4HLM A;  4HLG A;  4R6E A;  4KZU A;  4OQA C;  4HLH A;  2FAH A;  3U9Y A;  1UK0 A;  4UVX A;  3UA9 A;  4PY4 A;  4UFY A;  3SE2 A;  2RK8 A;  4BU6 A;  4UI8 A;  1KHF A;  4TOR A;  4L2G A;  1KHE A;  1KHG A;  3BLJ A;  4IJS A;  4L2F A;  5FH4 A;  4AVW A;  4WPV A;  4ZZZ A;  4LI8 A;  1K3D A;  4PNM A;  3KR7 A;  4LI6 A;  4UI4 A;  4TVJ A;  4UVT A;  4KRS A;  4L7N A;  3P0Q A;  4L34 A;  4OA7 A;  5ADS A;  4GNP A;  4X52 A;  4PNN A;  4BUW A;  4WOU A;  4UI3 A;  3U9H A;  4HLK A;  4UND A;  3UH2 A;  3L3L A;  4L32 A;  4GNQ A;  4L7U A;  5AL1 A;  4L7P A;  2QF2 A;  3MOH A;  4BUE A;  4BU8 A;  4TJY A;  4BHH B;  3MHJ A;  4PNL A;  4TKG A;  4HKI A;  3SMJ A;  4UVO A;  4J3L A;  3C49 A;  4UVU A;  4W6E A;  4UVW A;  3ZL9 A;  4WIE A;  4W5S A;  1OEN A;  2PXZ X;  4ZZY A;  2X5Y A;  4L0S A;  3MOF A;  5FH3 A;  3ZLA A;  3GJW A;  4L7O A;  4GNO A;  3P0N A;  4HKK A;  1KHB A;  4J21 A;  4BFP A;  4IUE A;  5AEH A;  4PNS A;  4UX4 A;  4GV7 A;  4WPU A;  3KJD A;  4GMZ A;  4TOS A;  4TJU A;  4BUS A;  4GV0 A;  4BJ9 A;  5ADQ A;  5ADT A;  2PAW A;  4KZQ A;  1II2 A;  1YLH A;  1UK1 A;  1AYL A;  4L31 A;  4F0E A;  4UVY A;  4BUX A;  4K4E A;  3W51 A;  4UVS A;  4GMU A;  4DQY C;  4L0T A;  4PNQ A;  4U6A A;  4GNM A;  4YW8 A;  1A26 A;  3DTB A;  4I9I A;  5FH0 A;  3DT4 A;  4PJT A;  4HLF A;  4UI5 A;  4PML A;  4J3M A;  4TK0 A;  1K3C A;  4UVL A;  4AVU A;  4UHG A;  2RKA A;  1WOK A;  2ZCI A;  1EFY A;  4R5W A;  2QF1 A;  3UH4 A;  4F1Q A;  4BUD A;  4MSK A;  4PJV A;  1J3B A; 
#chains in the Genus database with same CATH homology
 4HLG A;  4R6E A;  3MOF A;  1OS1 A;  5FH3 A;  4HHY A;  5LXP A;  4XHU A;  4KZU A;  3GJW A;  4OQA C;  5DCZ A;  4L7O A;  4L0I A;  4HLH A;  1YTM A;  2FAH A;  2RD6 A;  2OLQ A;  2PQF A;  3P0N A;  1KHB A;  4GNO A;  4HKK A;  1UK0 A;  4UI7 A;  4J21 A;  4WPT A;  5AKW A;  3U9Y A;  4BFP A;  4IUE A;  5ETY A;  2PY7 X;  4BU5 A;  5AEH A;  4HYF A;  4UFU A;  4PNS A;  4YWB A;  4BUT A;  4DVI A;  4UX4 A;  4GV7 A;  5ECE A;  3DT7 A;  2QZY A;  3KJD A;  4GMZ A;  4UVX A;  3MOE A;  4WPU A;  4YWD A;  4L70 A;  4UVZ A;  1M51 A;  4PAX A;  4TJU A;  3GOY A;  4TK5 A;  4TOS A;  4GV0 A;  4L33 A;  4BUS A;  4BJ9 A;  3UA9 A;  4BJB A;  4PY4 A;  5ADQ A;  4BUV A;  5ADT A;  4UFY A;  5AL5 A;  2PAW A;  4L6S A;  3KR8 A;  4KZL A;  1XKV A;  4KZQ A;  4N4T A;  3P0P A;  3SE2 A;  4OPX C;  1II2 A;  1YLH A;  2RK8 A;  4MSG A;  4UI8 A;  4BU6 A;  1KHF A;  4WL8 A;  4TOR A;  2RCW A;  4L2G A;  4RCG A;  1KHE A;  4BUA A;  1KHG A;  1UK1 A;  4L2K A;  3SMI A;  5FPF A;  3BLJ A;  4L0B A;  5FH1 A;  1AYL A;  4GMW A;  4L31 A;  4BU3 A;  4GV4 A;  4F0E A;  4UVY A;  4L10 A;  4UI6 A;  4L2F A;  4UXB A;  4OQB C;  4R43 A;  4TKI A;  2OLR A;  4TJW A;  5FH4 A;  4J22 A;  4BS4 A;  4AVW A;  4GV2 A;  4PNT A;  4WPV A;  4K4E A;  3W51 A;  4BU9 A;  4BUX A;  4UVS A;  4ZZZ A;  4LI8 A;  1K3D A;  2RK7 A;  3PAX A;  1GS0 A;  4GMU A;  4L7R A;  4PNM A;  4MT9 A;  3KR7 A;  2RF5 A;  4DQY C;  4L0T A;  4UVN A;  4UW1 A;  3MHK A;  4ZZX A;  2QEY A;  4PNQ A;  4L7L A;  2QEW A;  4U6A A;  4LI6 A;  4GNM A;  4UI4 A;  4M7B A;  4N3R A;  5C5P A;  4TVJ A;  4YW8 A;  3GN7 A;  4GMM A;  1A26 A;  1NHX A;  4HHZ A;  4KRS A;  4UVT A;  5LX6 A;  4L7N A;  3P0Q A;  3DTB A;  4I9I A;  4L34 A;  4OA7 A;  4L09 A;  3UDD A;  5FH0 A;  4BUF A;  5ADR A;  5ADS A;  4GNP A;  4PNR A;  4X52 A;  4PNN A;  3DT4 A;  4RV6 A;  5AKU A;  4BUU A;  4BUW A;  4WOU A;  4UI3 A;  4BUY A;  3U9H A;  4BUI A;  2PAX A;  4HLK A;  4UUH A;  4UND A;  3UH2 A;  3HKV A;  3L3L A;  1YGG A;  4L32 A;  4PJT A;  4WIU A;  4GNQ A;  4HLF A;  4OX2 A;  4L7U A;  4UI5 A;  5AL1 A;  3CE0 A;  4L7P A;  5A00 A;  2QF2 A;  4GNL A;  4J3M A;  4PML A;  5AL3 A;  3FHB A;  1K3C A;  3MOH A;  5FH2 A;  4TK0 A;  4BUE A;  4W5I A;  4UVL A;  4AVU A;  4BU8 A;  4TJY A;  5C5R A;  4HL5 A;  2RKA A;  4UHG A;  5AL2 A;  5C5Q A;  3GEY A;  1WOK A;  2RKE A;  3MHJ A;  4HMH A;  4L0V A;  4PNL A;  4TKG A;  2ZCI A;  4BU7 A;  4J1Z A;  4HKI A;  1EFY A;  2RKD A;  4LI7 A;  4TKF A;  3SMJ A;  1AQ2 A;  4R5W A;  4UVO A;  4HKN A;  3DT2 A;  4UVV A;  5LYH A;  1PAX A;  2QF1 A;  3L3M A;  3UH4 A;  4J3L A;  3C49 A;  4UVU A;  4W6E A;  4F1L A;  1YVY A;  5FPG A;  5I67 A;  4YW9 A;  4UVP A;  2PC9 A;  4K4F A;  3KCZ A;  4F1Q A;  4UVW A;  2GMV A;  4WIE A;  4BJC A;  4BUD A;  5FH5 A;  4N4V A;  4W5S A;  1OEN A;  2PXZ X;  4L6Z A;  4PJV A;  4ZZY A;  2FAF A;  4MSK A;  5AL4 A;  3C4H A;  1J3B A;  5EBT A;  2X5Y A;  4HLM A;  4L0S A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4L6SA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations