4QYQA

Crystal structure of the complex of goat lactoperoxidase with an antithyroid agent propylthiouracil at 2.5 a resolution
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
595
structure length
595
Chain Sequence
SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mode of binding of the antithyroid drug propylthiouracil to mammalian haem peroxidases
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Lactoperoxidase
total genus 176
structure length 595
sequence length 595
chains with identical sequence B, C, D
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2014-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 4qyqA00
4IG5A 3N8YB 3N8WB 3Q9KA 3QMOA 4M11A 3KRKA 4RUTA 2AYLA 5F19A 3R55A 4E1GA 5JVZA 2R5LA 4QJQA 3V6QA 1CQEA 1PXXA 3FNLA 3BXIA 3LN0A 4DL1C 4FM5A 5IKVA 4KVJA 3I6NA 3NIUA 2QPKA 3ZS0C 4Z0LA 5FDQA 3N8ZA 1PRHA 2QQTA 4KVLA 3KK6A 1DNWC 4RRYA 1IGZA 3N8XA 3ERHA 6COXA 1D2VC 3PY4A 3GCJA 3PGHA 1EQGA 3GCKA 3MQEA 4RRWA 3QH0A 3NTGA 3S4FA 3TZIA 3HS6A 3R4XA 4NT3A 2IKCA 3KRQA 2GJMA 5HPWA 2E9EA 3OLUA 3R5OA 5FF1A 3OGWA 3RR3A 1DNUC 1HT5A 3NAKA 4OEKA 1Q4GA 3QF1A 2IPSA 1PGEA 5IKQA 2PT3A 1CVUA 4COXA 4PNXA 1D7WC 5GLSA 2QRBA 4QYQA 2NQXA 1DDXA 3TGYA 3UBAA 5B72A 3MDLA 4NJBA 3GCLA 3GC1A 3N8VA 4OTYA 3NTBA 1PTHA 5F1AA 3FAQA 4M10A 3ERIA 1MHLC 3LN1A 2EFBA 2OYUP 3F9PC 4OTJA 4PH9A 5JVYA 3N8FA 1DIYA 2OJVA 4N7AA 3NT1A 3HS7A 3QL6A 3R5QA 4RRZA 4HHSA 3RKEA 5FIWC 4C1MC 1HT8A 2PUMA 4MSFA 4Y55A 5COXA 5IKTA 4KSZA 3NYHA 4KVKA 3Q7DA 5GH0A 5JW1A 3ZS1C 1FE2A 4O1ZA 3OLTA 5KIRA 4HHRA 4RS0A 2Z5ZA 1U67A 5IKRA 1EBVA 1EQHA 4RRXA 1CXPC 1D5LC 2EHAA 3HS5A 2OYEP 3SXVA 3N8YA 2O86A 3N8WA 4GM7A 1IGXA 4LJJA 1CX2A 4GN6A 1MYPC
chains in the Genus database with same CATH superfamily
4IG5A 3N8YB 3N8WB 3Q9KA 3QMOA 4M11A 3KRKA 4RUTA 2AYLA 5F19A 3R55A 4E1GA 5JVZA 2R5LA 4QJQA 3V6QA 1CQEA 1PXXA 3FNLA 3BXIA 3LN0A 4DL1C 4FM5A 5IKVA 4KVJA 3I6NA 3NIUA 2QPKA 3ZS0C 4Z0LA 5FDQA 3N8ZA 1PRHA 2QQTA 4KVLA 3KK6A 1DNWC 4RRYA 1IGZA 3N8XA 3ERHA 6COXA 1D2VC 3PY4A 3GCJA 3PGHA 1EQGA 3GCKA 3MQEA 4RRWA 3QH0A 3NTGA 3S4FA 3TZIA 3HS6A 3R4XA 4NT3A 2IKCA 3KRQA 2GJMA 5HPWA 2E9EA 3OLUA 3R5OA 5FF1A 3OGWA 3RR3A 1DNUC 1HT5A 3NAKA 4OEKA 1Q4GA 3QF1A 2IPSA 1PGEA 5IKQA 2PT3A 1CVUA 4COXA 4PNXA 1D7WC 5GLSA 2QRBA 4QYQA 2NQXA 1DDXA 3TGYA 3UBAA 5B72A 3MDLA 4NJBA 3GCLA 3GC1A 3N8VA 4OTYA 3NTBA 1PTHA 5F1AA 3FAQA 4M10A 3ERIA 1MHLC 3LN1A 2EFBA 2OYUP 3F9PC 4OTJA 4PH9A 5JVYA 3N8FA 1DIYA 2OJVA 4N7AA 3NT1A 3HS7A 3QL6A 3R5QA 4RRZA 4HHSA 3RKEA 5FIWC 4C1MC 1HT8A 2PUMA 4MSFA 4Y55A 5COXA 5IKTA 4KSZA 3NYHA 4KVKA 3Q7DA 5GH0A 5JW1A 3ZS1C 1FE2A 4O1ZA 3OLTA 5KIRA 4HHRA 4RS0A 2Z5ZA 1U67A 5IKRA 1EBVA 1EQHA 4RRXA 1CXPC 1D5LC 2EHAA 3HS5A 2OYEP 3SXVA 3N8YA 2O86A 3N8WA 4GM7A 1IGXA 4LJJA 1CX2A 4GN6A 1MYPC
chains in the Genus database with same CATH topology
4IG5A 3N8YB 3N8WB 3Q9KA 3QMOA 4M11A 3KRKA 4RUTA 2AYLA 5F19A 3R55A 4E1GA 5JVZA 2R5LA 4QJQA 3V6QA 1CQEA 1PXXA 3FNLA 3BXIA 3LN0A 4DL1C 4FM5A 5IKVA 4KVJA 3I6NA 3NIUA 2QPKA 3ZS0C 4Z0LA 5FDQA 3N8ZA 1PRHA 2QQTA 4KVLA 3KK6A 1DNWC 4RRYA 1IGZA 3N8XA 3ERHA 6COXA 1D2VC 3PY4A 3GCJA 3PGHA 1EQGA 3GCKA 3MQEA 4RRWA 3QH0A 3NTGA 3S4FA 3TZIA 3HS6A 3R4XA 4NT3A 2IKCA 3KRQA 2GJMA 5HPWA 2E9EA 3OLUA 3R5OA 5FF1A 3OGWA 3RR3A 1DNUC 1HT5A 3NAKA 4OEKA 1Q4GA 3QF1A 2IPSA 1PGEA 5IKQA 2PT3A 1CVUA 4COXA 4PNXA 1D7WC 5GLSA 2QRBA 4QYQA 2NQXA 1DDXA 3TGYA 3UBAA 5B72A 3MDLA 4NJBA 3GCLA 3GC1A 3N8VA 4OTYA 3NTBA 1PTHA 5F1AA 3FAQA 4M10A 3ERIA 1MHLC 3LN1A 2EFBA 2OYUP 3F9PC 4OTJA 4PH9A 5JVYA 3N8FA 1DIYA 2OJVA 4N7AA 3NT1A 3HS7A 3QL6A 3R5QA 4RRZA 4HHSA 3RKEA 5FIWC 4C1MC 1HT8A 2PUMA 4MSFA 4Y55A 5COXA 5IKTA 4KSZA 3NYHA 4KVKA 3Q7DA 5GH0A 5JW1A 3ZS1C 1FE2A 4O1ZA 3OLTA 5KIRA 4HHRA 4RS0A 2Z5ZA 1U67A 5IKRA 1EBVA 1EQHA 4RRXA 1CXPC 1D5LC 2EHAA 3HS5A 2OYEP 3SXVA 3N8YA 2O86A 3N8WA 4GM7A 1IGXA 4LJJA 1CX2A 4GN6A 1MYPC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IG5 A;  3N8Y B;  3N8W B;  3Q9K A;  3QMO A;  4M11 A;  3KRK A;  4RUT A;  2AYL A;  5F19 A;  3R55 A;  4E1G A;  5JVZ A;  2R5L A;  4QJQ A;  3V6Q A;  1CQE A;  1PXX A;  3FNL A;  3BXI A;  3LN0 A;  4DL1 C;  4FM5 A;  5IKV A;  4KVJ A;  3I6N A;  3NIU A;  2QPK A;  3ZS0 C;  4Z0L A;  5FDQ A;  3N8Z A;  1PRH A;  2QQT A;  4KVL A;  3KK6 A;  1DNW C;  4RRY A;  1IGZ A;  3N8X A;  3ERH A;  6COX A;  1D2V C;  3PY4 A;  3GCJ A;  3PGH A;  1EQG A;  3GCK A;  3MQE A;  4RRW A;  3QH0 A;  3NTG A;  3S4F A;  3TZI A;  3HS6 A;  3R4X A;  4NT3 A;  2IKC A;  3KRQ A;  2GJM A;  5HPW A;  2E9E A;  3OLU A;  3R5O A;  5FF1 A;  3OGW A;  3RR3 A;  1DNU C;  1HT5 A;  3NAK A;  4OEK A;  1Q4G A;  3QF1 A;  2IPS A;  1PGE A;  5IKQ A;  2PT3 A;  1CVU A;  4COX A;  4PNX A;  1D7W C;  5GLS A;  2QRB A;  4QYQ A;  2NQX A;  1DDX A;  3TGY A;  3UBA A;  5B72 A;  3MDL A;  4NJB A;  3GCL A;  3GC1 A;  3N8V A;  4OTY A;  3NTB A;  1PTH A;  5F1A A;  3FAQ A;  4M10 A;  3ERI A;  1MHL C;  3LN1 A;  2EFB A;  2OYU P;  3F9P C;  4OTJ A;  4PH9 A;  5JVY A;  3N8F A;  1DIY A;  2OJV A;  4N7A A;  3NT1 A;  3HS7 A;  3QL6 A;  3R5Q A;  4RRZ A;  4HHS A;  3RKE A;  5FIW C;  4C1M C;  1HT8 A;  2PUM A;  4MSF A;  4Y55 A;  5COX A;  5IKT A;  4KSZ A;  3NYH A;  4KVK A;  3Q7D A;  5GH0 A;  5JW1 A;  3ZS1 C;  1FE2 A;  4O1Z A;  3OLT A;  5KIR A;  4HHR A;  4RS0 A;  2Z5Z A;  1U67 A;  5IKR A;  1EBV A;  1EQH A;  4RRX A;  1CXP C;  1D5L C;  2EHA A;  3HS5 A;  2OYE P;  3SXV A;  3N8Y A;  2O86 A;  3N8W A;  4GM7 A;  1IGX A;  4LJJ A;  1CX2 A;  4GN6 A;  1MYP C; 
#chains in the Genus database with same CATH topology
 4IG5 A;  3N8Y B;  3N8W B;  3Q9K A;  3QMO A;  4M11 A;  3KRK A;  4RUT A;  2AYL A;  5F19 A;  3R55 A;  4E1G A;  5JVZ A;  2R5L A;  4QJQ A;  3V6Q A;  1CQE A;  1PXX A;  3FNL A;  3BXI A;  3LN0 A;  4DL1 C;  4FM5 A;  5IKV A;  4KVJ A;  3I6N A;  3NIU A;  2QPK A;  3ZS0 C;  4Z0L A;  5FDQ A;  3N8Z A;  1PRH A;  2QQT A;  4KVL A;  3KK6 A;  1DNW C;  4RRY A;  1IGZ A;  3N8X A;  3ERH A;  6COX A;  1D2V C;  3PY4 A;  3GCJ A;  3PGH A;  1EQG A;  3GCK A;  3MQE A;  4RRW A;  3QH0 A;  3NTG A;  3S4F A;  3TZI A;  3HS6 A;  3R4X A;  4NT3 A;  2IKC A;  3KRQ A;  2GJM A;  5HPW A;  2E9E A;  3OLU A;  3R5O A;  5FF1 A;  3OGW A;  3RR3 A;  1DNU C;  1HT5 A;  3NAK A;  4OEK A;  1Q4G A;  3QF1 A;  2IPS A;  1PGE A;  5IKQ A;  2PT3 A;  1CVU A;  4COX A;  4PNX A;  1D7W C;  5GLS A;  2QRB A;  4QYQ A;  2NQX A;  1DDX A;  3TGY A;  3UBA A;  5B72 A;  3MDL A;  4NJB A;  3GCL A;  3GC1 A;  3N8V A;  4OTY A;  3NTB A;  1PTH A;  5F1A A;  3FAQ A;  4M10 A;  3ERI A;  1MHL C;  3LN1 A;  2EFB A;  2OYU P;  3F9P C;  4OTJ A;  4PH9 A;  5JVY A;  3N8F A;  1DIY A;  2OJV A;  4N7A A;  3NT1 A;  3HS7 A;  3QL6 A;  3R5Q A;  4RRZ A;  4HHS A;  3RKE A;  5FIW C;  4C1M C;  1HT8 A;  2PUM A;  4MSF A;  4Y55 A;  5COX A;  5IKT A;  4KSZ A;  3NYH A;  4KVK A;  3Q7D A;  5GH0 A;  5JW1 A;  3ZS1 C;  1FE2 A;  4O1Z A;  3OLT A;  5KIR A;  4HHR A;  4RS0 A;  2Z5Z A;  1U67 A;  5IKR A;  1EBV A;  1EQH A;  4RRX A;  1CXP C;  1D5L C;  2EHA A;  3HS5 A;  2OYE P;  3SXV A;  3N8Y A;  2O86 A;  3N8W A;  4GM7 A;  1IGX A;  4LJJ A;  1CX2 A;  4GN6 A;  1MYP C; 
#chains in the Genus database with same CATH homology
 4IG5 A;  3N8Y B;  3N8W B;  3Q9K A;  3QMO A;  4M11 A;  3KRK A;  4RUT A;  2AYL A;  5F19 A;  3R55 A;  4E1G A;  5JVZ A;  2R5L A;  4QJQ A;  3V6Q A;  1CQE A;  1PXX A;  3FNL A;  3BXI A;  3LN0 A;  4DL1 C;  4FM5 A;  5IKV A;  4KVJ A;  3I6N A;  3NIU A;  2QPK A;  3ZS0 C;  4Z0L A;  5FDQ A;  3N8Z A;  1PRH A;  2QQT A;  4KVL A;  3KK6 A;  1DNW C;  4RRY A;  1IGZ A;  3N8X A;  3ERH A;  6COX A;  1D2V C;  3PY4 A;  3GCJ A;  3PGH A;  1EQG A;  3GCK A;  3MQE A;  4RRW A;  3QH0 A;  3NTG A;  3S4F A;  3TZI A;  3HS6 A;  3R4X A;  4NT3 A;  2IKC A;  3KRQ A;  2GJM A;  5HPW A;  2E9E A;  3OLU A;  3R5O A;  5FF1 A;  3OGW A;  3RR3 A;  1DNU C;  1HT5 A;  3NAK A;  4OEK A;  1Q4G A;  3QF1 A;  2IPS A;  1PGE A;  5IKQ A;  2PT3 A;  1CVU A;  4COX A;  4PNX A;  1D7W C;  5GLS A;  2QRB A;  4QYQ A;  2NQX A;  1DDX A;  3TGY A;  3UBA A;  5B72 A;  3MDL A;  4NJB A;  3GCL A;  3GC1 A;  3N8V A;  4OTY A;  3NTB A;  1PTH A;  5F1A A;  3FAQ A;  4M10 A;  3ERI A;  1MHL C;  3LN1 A;  2EFB A;  2OYU P;  3F9P C;  4OTJ A;  4PH9 A;  5JVY A;  3N8F A;  1DIY A;  2OJV A;  4N7A A;  3NT1 A;  3HS7 A;  3QL6 A;  3R5Q A;  4RRZ A;  4HHS A;  3RKE A;  5FIW C;  4C1M C;  1HT8 A;  2PUM A;  4MSF A;  4Y55 A;  5COX A;  5IKT A;  4KSZ A;  3NYH A;  4KVK A;  3Q7D A;  5GH0 A;  5JW1 A;  3ZS1 C;  1FE2 A;  4O1Z A;  3OLT A;  5KIR A;  4HHR A;  4RS0 A;  2Z5Z A;  1U67 A;  5IKR A;  1EBV A;  1EQH A;  4RRX A;  1CXP C;  1D5L C;  2EHA A;  3HS5 A;  2OYE P;  3SXV A;  3N8Y A;  2O86 A;  3N8W A;  4GM7 A;  1IGX A;  4LJJ A;  1CX2 A;  4GN6 A;  1MYP C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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