4RV6 | Genus

Total Genus 110

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	110
sequence length	349
structure length	347
Chain Sequence	KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transferase/transferase inhibitor
source organism	Homo sapiens
publication title	Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. pubmed doi rcsb
molecule keywords	Poly [ADP-ribose] polymerase 1
total genus	110
structure length	347
sequence length	349
chains with identical sequence	B, C, D
ec nomenclature	ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date	2014-11-25

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00644	PARP	Poly(ADP-ribose) polymerase catalytic domain
A	PF02877	PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.142.10	Mainly Alpha	Up-down Bundle	Poly(ADP-ribose) Polymerase; domain 1	Poly(ADP-ribose) polymerase, regulatory domain	4rv6A01
3.90.228.10	Alpha Beta	Alpha-Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 3	Phosphoenolpyruvate Carboxykinase; domain 3	4rv6A02

2X5YA 4HKIA 4L32A 4UI8A 5AL5A 4L7PA 2RF5A 5C5PA 4BJCA 4HL5A 4W5IA 4R6EA 3P0PA 4BUIA 4HMHA 4RV6A 4UVZA 3MHJA 3L3MA 4HLFA 1UK0A 4UI5A 4PNSA 5AEHA 4L7OA 5AKUA 5ECEA 4BS4A 3GOYA 5FPFA 4W6EA 4AVWA 4I9IA 4L31A 4PNMA 4BUTA 3KR7A 4GV2A 4OQAC 3UH2A 4UFUA 4L10A 4HKKA 4BUYA 4BJ9A 2RD6A 3UDDA 4UVUA 1GS0A 3C4HA 4TK5A 4TORA 4UUHA 4TK0A 4PNLA 4BU3A 4R5WA 4L34A 4KZLA 4HKNA 3P0NA 4BUWA 4HLMA 4UVTA 5ADSA 3C49A 4UVWA 4L7LA 5LXPA 5LYHA 3L3LA 4N4VA 4UHGA 4BU7A 4J21A 4BUDA 4L0TA 4N3RA 4L6SA 4F0EA 4L7UA 4PY4A 3W51A 4BU5A 4UVPA 4UVLA 4BFPA 4L0VA 5C5QA 3U9HA 4BUSA 2RCWA 5AL1A 4MSKA 4XHUA 4TKIA 5EBTA 3P0QA 4F1QA 4BUAA 3PAXA 4OA7A 4OQBC 4L7RA 3SE2A 4HHYA 4IUEA 4PNNA 4U6AA 4BUXA 4J22A 4UVNA 1WOKA 4LI7A 4TJUA 4TOSA 4UI7A 5LX6A 4J1ZA 4LI8A 4L0SA 2PAWA 4L33A 3KR8A 4UVOA 4X52A 3BLJA 4GV0A 4L0BA 4L09A 5ETYA 4AVUA 3CE0A 3KCZA 4TJYA 4L7NA 4TKFA 5AL3A 1UK1A 4KZUA 4F1LA 4K4FA 4BUFA 4PMLA 4K4EA 4GV7A 4PNRA 4MSGA 4W5SA 4UI6A 4L70A 3MHKA 4UVYA 4ZZXA 2PAXA 4LI6A 4M7BA 3SMJA 4BUVA 4PJTA 1A26A 5C5RA 3GN7A 4KZQA 4PNTA 5AL4A 1EFYA 4HLHA 4ZZZA 4OPXC 4HLGA 4UNDA 4PNQA 4L2FA 4L2GA 4TJWA 4UX4A 4UW1A 2PQFA 4UI3A 3GJWA 4BU8A 4UVXA 3KJDA 4DVIA 5AKWA 4J3LA 4PAXA 4UXBA 4ZZYA 4L0IA 4KRSA 4L2KA 4HHZA 3HKVA 4N4TA 5A00A 5FPGA 5AL2A 4BUUA 3SMIA 3FHBA 4J3MA 5DCZA 4BU9A 4HLKA 4L6ZA 4BUEA 4BU6A 4PJVA 3UA9A 4UFYA 4UVVA 4BJBA 4UI4A 3GEYA 4MT9A 4DQYC 4UVSA 4TVJA 5ADTA 4HYFA 1PAXA 3UH4A 5ADRA 4GV4A 3U9YA 4TKGA 5ADQA
chains in the Genus database with same CATH superfamily

2X5YA 1KHEA 5AL5A 2RF5A 5C5PA 1KHBA 3MHJA 1XKVA 4W6EA 5FH4A 1YGGA 4UFUA 2RD6A 4TORA 4PNLA 4L34A 3P0NA 4BUWA 4HLMA 4UVTA 5ADSA 4UVWA 5LXPA 5LYHA 4J1GA 2RKEA 4L6SA 3W51A 4BFPA 5C5QA 5AL1A 4TKIA 4XHUA 5EBTA 4OA7A 4GNPA 1WOKA 4TOSA 4WL8A 4UI7A 5LX6A 4WPTA 3KR8A 3BLJA 4WPUA 5ETYA 4AVUA 4L7NA 2QEYA 4BUFA 4PMLA 4BUVA 4PJTA 5C5RA 3GN7A 4HLHA 4ZZZA 4UNDA 4UW1A 4UI3A 3GJWA 4BU8A 4UVXA 4DVIA 4J3LA 4UXBA 5FH5A 5A00A 4J3MA 4HLKA 4BU6A 4UVVA 4GNLA 4TVJA 1II2A 4HYFA 2QF1A 4BJCA 4W5IA 4R6EA 3P0PA 4HMHA 1UK0A 4UI5A 4PNSA 3MOEA 5AKUA 5ECEA 4BS4A 3GOYA 4GV2A 3UH2A 4GMMA 4HKKA 4IDUB 4BU3A 4R5WA 4BGPA 3C49A 4L7LA 3ZL9A 3L3LA 4BU7A 4BUDA 4JNGA 2OLQA 4YWBA 3DTBA 4L0VA 2RCWA 4MSKA 1OENA 4F1QA 4BUAA 4OQBC 4L7RA 3SE2A 4HHYA 4TJUA 1J3BA 4L0BA 4L09A 4WOUA 5AL3A 2RKDA 3ZLAA 3MOHA 4UI6A 3MHKA 2PAXA 4LI6A 4M7BA 1K3DA 4KZQA 5AL4A 1EFYA 4L2FA 3KJDA 3DT4A 2GMVA 5AKWA 4GNOA 4ZZYA 4KRSA 4HHZA 4BU9A 3FHBA 4WIUA 1M51A 4BJBA 2RK8A 3GEYA 4UVSA 5ADTA 4HKIA 4L32A 4GMZA 4HL5A 4RV6A 4UVZA 3L3MA 1AYLA 5AEHA 4YW9A 4L7OA 4I9IA 4L31A 4PNMA 4BUTA 4BHHB 3KR7A 4OQAC 4L10A 3UDDA 4UVUA 1GS0A 3C4HA 2PY7X 2PC9A 4KZLA 4N4VA 4UHGA 2ZCIA 4J21A 2FAHA 4F0EA 4L7UA 4PY4A 4UVLA 3U9HA 4BUSA 4IDUA 3P0QA 4IUEA 4BUXA 4UVNA 4J1ZA 2PAWA 4L33A 4UVOA 4X52A 4GV0A 5FH3A 3CE0A 2RKAA 1KHGA 1UK1A 4KZUA 4F1LA 1AQ2A 4W5SA 2QF2A 5I67A 3SMJA 1A26A 4PNTA 4R43A 3DT7A 4OPXC 4HLGA 4PNQA 4L2GA 1KHFA 2FAFA 4L2KA 3HKVA 4N4TA 4BUUA 1YVYA 5AL2A 3SMIA 4L6ZA 4BUEA 4PJVA 3MOFA 4UI4A 4DQYC 2QZYA 3UH4A 4WPVA 4GV4A 4IJSA 4TKGA 5ADQA 1YTMA 5FH1A 4UI8A 4L7PA 2OLRA 4BUIA 4HLFA 4GMWA 5FPFA 4AVWA 4BUYA 4BJ9A 4TK5A 4UUHA 4TK0A 4HKNA 4OX2A 2QEWA 4IDXA 4WIEA 4L0TA 4N3RA 4BU5A 1YLHA 4UVPA 4GNMA 4RCGA 3PAXA 4PNNA 4U6AA 4J22A 4LI7A 4LI8A 1NHXA 4L0SA 4J1JA 5FH0A 3KCZA 4TJYA 4TKFA 4YW8A 4K4FA 4K4EA 4GV7A 4PNRA 4MSGA 4L70A 4UVYA 4ZZXA 4GNQA 4TJWA 4UX4A 5FH2A 2PQFA 1OS1A 1K3CA 4PAXA 2PXZX 4L0IA 4GMUA 5FPGA 5DCZA 4YWDA 3UA9A 4UFYA 4MT9A 1PAXA 3DT2A 2RK7A 5ADRA 3U9YA
chains in the Genus database with same CATH topology

2X5YA 5FH1A 4HKIA 4L32A 4UI8A 1KHEA 4L7PA 4GMZA 2RF5A 5AL5A 2OLRA 5C5PA 4BJCA 1KHBA 4HL5A 4W5IA 4R6EA 3P0PA 4BUIA 4HMHA 4RV6A 4UVZA 3MHJA 3L3MA 4HLFA 1UK0A 1XKVA 4UI5A 1AYLA 4GMWA 4PNSA 3MOEA 4YW9A 5AEHA 4L7OA 5AKUA 5ECEA 4BS4A 3GOYA 5FPFA 4W6EA 4AVWA 4I9IA 4L31A 4PNMA 4BUTA 3KR7A 5FH4A 4GV2A 4OQAC 3UH2A 1YGGA 4GMMA 4L10A 4HKKA 4UFUA 4BUYA 4BJ9A 2RD6A 3UDDA 4UVUA 1GS0A 3C4HA 4TK5A 2PY7X 4TORA 4UUHA 4PNLA 2PC9A 4BU3A 4TK0A 4R5WA 4L34A 4KZLA 4HKNA 3P0NA 4BUWA 4HLMA 4UVTA 5ADSA 3C49A 4OX2A 4L7LA 4UVWA 2QEWA 5LXPA 5LYHA 3L3LA 4N4VA 4UHGA 2ZCIA 4BU7A 4J21A 2RKEA 4WIEA 4BUDA 2OLQA 2FAHA 4L0TA 4N3RA 4L6SA 4F0EA 4L7UA 4PY4A 3W51A 4YWBA 4BU5A 1YLHA 4UVPA 4UVLA 4BFPA 3DTBA 4GNMA 4L0VA 5C5QA 4RCGA 3U9HA 4BUSA 2RCWA 5AL1A 4MSKA 4XHUA 4TKIA 1OENA 5EBTA 3P0QA 4F1QA 4BUAA 3PAXA 4OA7A 4OQBC 4L7RA 3SE2A 4GNPA 4HHYA 4IUEA 4PNNA 4U6AA 4BUXA 4J22A 4UVNA 1WOKA 4LI7A 4TJUA 4TOSA 1J3BA 4WL8A 4UI7A 5LX6A 4J1ZA 4LI8A 1NHXA 4L0SA 4WPTA 2PAWA 4L33A 3KR8A 4UVOA 4X52A 5FH0A 3BLJA 4WPUA 4GV0A 4L0BA 4L09A 5ETYA 4AVUA 3CE0A 3KCZA 5FH3A 2RKAA 1KHGA 4TJYA 4L7NA 2QEYA 4WOUA 4TKFA 5AL3A 4YW8A 1UK1A 4KZUA 4F1LA 4K4FA 4BUFA 2RKDA 4PMLA 1AQ2A 4K4EA 4GV7A 4PNRA 3MOHA 4MSGA 4W5SA 4UI6A 4L70A 2QF2A 3MHKA 4UVYA 4ZZXA 2PAXA 5I67A 4LI6A 4M7BA 3SMJA 4BUVA 4PJTA 1A26A 5C5RA 1K3DA 3GN7A 4KZQA 4PNTA 4R43A 5AL4A 3DT7A 1EFYA 4HLHA 4GNQA 4ZZZA 4OPXC 4HLGA 4UNDA 4PNQA 4L2FA 4L2GA 4TJWA 4UX4A 5FH2A 4UW1A 2PQFA 4UI3A 1KHFA 3GJWA 4BU8A 2FAFA 3KJDA 3DT4A 4UVXA 2GMVA 5AKWA 1OS1A 4DVIA 1K3CA 4GNOA 4J3LA 4PAXA 4UXBA 4ZZYA 2PXZX 4KRSA 4GMUA 4L0IA 4L2KA 4HHZA 3HKVA 5FH5A 4N4TA 5A00A 5FPGA 1YVYA 5AL2A 4BUUA 3SMIA 3FHBA 4J3MA 5DCZA 4BU9A 4HLKA 4L6ZA 4BUEA 4BU6A 4PJVA 4YWDA 3UA9A 4WIUA 4UFYA 4UVVA 1M51A 4BJBA 3MOFA 2RK8A 4GNLA 4UI4A 3GEYA 4MT9A 4DQYC 4UVSA 4TVJA 2QZYA 5ADTA 1II2A 1PAXA 3DT2A 2RK7A 4HYFA 3UH4A 4WPVA 4GV4A 5ADRA 3U9YA 2QF1A 4TKGA 5ADQA 1YTMA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2X5Y A;  4HKI A;  4L32 A;  4UI8 A;  5AL5 A;  4L7P A;  2RF5 A;  5C5P A;  4BJC A;  4HL5 A;  4W5I A;  4R6E A;  3P0P A;  4BUI A;  4HMH A;  4RV6 A;  4UVZ A;  3MHJ A;  3L3M A;  4HLF A;  1UK0 A;  4UI5 A;  4PNS A;  5AEH A;  4L7O A;  5AKU A;  5ECE A;  4BS4 A;  3GOY A;  5FPF A;  4W6E A;  4AVW A;  4I9I A;  4L31 A;  4PNM A;  4BUT A;  3KR7 A;  4GV2 A;  4OQA C;  3UH2 A;  4UFU A;  4L10 A;  4HKK A;  4BUY A;  4BJ9 A;  2RD6 A;  3UDD A;  4UVU A;  1GS0 A;  3C4H A;  4TK5 A;  4TOR A;  4UUH A;  4TK0 A;  4PNL A;  4BU3 A;  4R5W A;  4L34 A;  4KZL A;  4HKN A;  3P0N A;  4BUW A;  4HLM A;  4UVT A;  5ADS A;  3C49 A;  4UVW A;  4L7L A;  5LXP A;  5LYH A;  3L3L A;  4N4V A;  4UHG A;  4BU7 A;  4J21 A;  4BUD A;  4L0T A;  4N3R A;  4L6S A;  4F0E A;  4L7U A;  4PY4 A;  3W51 A;  4BU5 A;  4UVP A;  4UVL A;  4BFP A;  4L0V A;  5C5Q A;  3U9H A;  4BUS A;  2RCW A;  5AL1 A;  4MSK A;  4XHU A;  4TKI A;  5EBT A;  3P0Q A;  4F1Q A;  4BUA A;  3PAX A;  4OA7 A;  4OQB C;  4L7R A;  3SE2 A;  4HHY A;  4IUE A;  4PNN A;  4U6A A;  4BUX A;  4J22 A;  4UVN A;  1WOK A;  4LI7 A;  4TJU A;  4TOS A;  4UI7 A;  5LX6 A;  4J1Z A;  4LI8 A;  4L0S A;  2PAW A;  4L33 A;  3KR8 A;  4UVO A;  4X52 A;  3BLJ A;  4GV0 A;  4L0B A;  4L09 A;  5ETY A;  4AVU A;  3CE0 A;  3KCZ A;  4TJY A;  4L7N A;  4TKF A;  5AL3 A;  1UK1 A;  4KZU A;  4F1L A;  4K4F A;  4BUF A;  4PML A;  4K4E A;  4GV7 A;  4PNR A;  4MSG A;  4W5S A;  4UI6 A;  4L70 A;  3MHK A;  4UVY A;  4ZZX A;  2PAX A;  4LI6 A;  4M7B A;  3SMJ A;  4BUV A;  4PJT A;  1A26 A;  5C5R A;  3GN7 A;  4KZQ A;  4PNT A;  5AL4 A;  1EFY A;  4HLH A;  4ZZZ A;  4OPX C;  4HLG A;  4UND A;  4PNQ A;  4L2F A;  4L2G A;  4TJW A;  4UX4 A;  4UW1 A;  2PQF A;  4UI3 A;  3GJW A;  4BU8 A;  4UVX A;  3KJD A;  4DVI A;  5AKW A;  4J3L A;  4PAX A;  4UXB A;  4ZZY A;  4L0I A;  4KRS A;  4L2K A;  4HHZ A;  3HKV A;  4N4T A;  5A00 A;  5FPG A;  5AL2 A;  4BUU A;  3SMI A;  3FHB A;  4J3M A;  5DCZ A;  4BU9 A;  4HLK A;  4L6Z A;  4BUE A;  4BU6 A;  4PJV A;  3UA9 A;  4UFY A;  4UVV A;  4BJB A;  4UI4 A;  3GEY A;  4MT9 A;  4DQY C;  4UVS A;  4TVJ A;  5ADT A;  4HYF A;  1PAX A;  3UH4 A;  5ADR A;  4GV4 A;  3U9Y A;  4TKG A;  5ADQ A; 
#chains in the Genus database with same CATH topology
 2X5Y A;  1KHE A;  5AL5 A;  2RF5 A;  5C5P A;  1KHB A;  3MHJ A;  1XKV A;  4W6E A;  5FH4 A;  1YGG A;  4UFU A;  2RD6 A;  4TOR A;  4PNL A;  4L34 A;  3P0N A;  4BUW A;  4HLM A;  4UVT A;  5ADS A;  4UVW A;  5LXP A;  5LYH A;  4J1G A;  2RKE A;  4L6S A;  3W51 A;  4BFP A;  5C5Q A;  5AL1 A;  4TKI A;  4XHU A;  5EBT A;  4OA7 A;  4GNP A;  1WOK A;  4TOS A;  4WL8 A;  4UI7 A;  5LX6 A;  4WPT A;  3KR8 A;  3BLJ A;  4WPU A;  5ETY A;  4AVU A;  4L7N A;  2QEY A;  4BUF A;  4PML A;  4BUV A;  4PJT A;  5C5R A;  3GN7 A;  4HLH A;  4ZZZ A;  4UND A;  4UW1 A;  4UI3 A;  3GJW A;  4BU8 A;  4UVX A;  4DVI A;  4J3L A;  4UXB A;  5FH5 A;  5A00 A;  4J3M A;  4HLK A;  4BU6 A;  4UVV A;  4GNL A;  4TVJ A;  1II2 A;  4HYF A;  2QF1 A;  4BJC A;  4W5I A;  4R6E A;  3P0P A;  4HMH A;  1UK0 A;  4UI5 A;  4PNS A;  3MOE A;  5AKU A;  5ECE A;  4BS4 A;  3GOY A;  4GV2 A;  3UH2 A;  4GMM A;  4HKK A;  4IDU B;  4BU3 A;  4R5W A;  4BGP A;  3C49 A;  4L7L A;  3ZL9 A;  3L3L A;  4BU7 A;  4BUD A;  4JNG A;  2OLQ A;  4YWB A;  3DTB A;  4L0V A;  2RCW A;  4MSK A;  1OEN A;  4F1Q A;  4BUA A;  4OQB C;  4L7R A;  3SE2 A;  4HHY A;  4TJU A;  1J3B A;  4L0B A;  4L09 A;  4WOU A;  5AL3 A;  2RKD A;  3ZLA A;  3MOH A;  4UI6 A;  3MHK A;  2PAX A;  4LI6 A;  4M7B A;  1K3D A;  4KZQ A;  5AL4 A;  1EFY A;  4L2F A;  3KJD A;  3DT4 A;  2GMV A;  5AKW A;  4GNO A;  4ZZY A;  4KRS A;  4HHZ A;  4BU9 A;  3FHB A;  4WIU A;  1M51 A;  4BJB A;  2RK8 A;  3GEY A;  4UVS A;  5ADT A;  4HKI A;  4L32 A;  4GMZ A;  4HL5 A;  4RV6 A;  4UVZ A;  3L3M A;  1AYL A;  5AEH A;  4YW9 A;  4L7O A;  4I9I A;  4L31 A;  4PNM A;  4BUT A;  4BHH B;  3KR7 A;  4OQA C;  4L10 A;  3UDD A;  4UVU A;  1GS0 A;  3C4H A;  2PY7 X;  2PC9 A;  4KZL A;  4N4V A;  4UHG A;  2ZCI A;  4J21 A;  2FAH A;  4F0E A;  4L7U A;  4PY4 A;  4UVL A;  3U9H A;  4BUS A;  4IDU A;  3P0Q A;  4IUE A;  4BUX A;  4UVN A;  4J1Z A;  2PAW A;  4L33 A;  4UVO A;  4X52 A;  4GV0 A;  5FH3 A;  3CE0 A;  2RKA A;  1KHG A;  1UK1 A;  4KZU A;  4F1L A;  1AQ2 A;  4W5S A;  2QF2 A;  5I67 A;  3SMJ A;  1A26 A;  4PNT A;  4R43 A;  3DT7 A;  4OPX C;  4HLG A;  4PNQ A;  4L2G A;  1KHF A;  2FAF A;  4L2K A;  3HKV A;  4N4T A;  4BUU A;  1YVY A;  5AL2 A;  3SMI A;  4L6Z A;  4BUE A;  4PJV A;  3MOF A;  4UI4 A;  4DQY C;  2QZY A;  3UH4 A;  4WPV A;  4GV4 A;  4IJS A;  4TKG A;  5ADQ A;  1YTM A;  5FH1 A;  4UI8 A;  4L7P A;  2OLR A;  4BUI A;  4HLF A;  4GMW A;  5FPF A;  4AVW A;  4BUY A;  4BJ9 A;  4TK5 A;  4UUH A;  4TK0 A;  4HKN A;  4OX2 A;  2QEW A;  4IDX A;  4WIE A;  4L0T A;  4N3R A;  4BU5 A;  1YLH A;  4UVP A;  4GNM A;  4RCG A;  3PAX A;  4PNN A;  4U6A A;  4J22 A;  4LI7 A;  4LI8 A;  1NHX A;  4L0S A;  4J1J A;  5FH0 A;  3KCZ A;  4TJY A;  4TKF A;  4YW8 A;  4K4F A;  4K4E A;  4GV7 A;  4PNR A;  4MSG A;  4L70 A;  4UVY A;  4ZZX A;  4GNQ A;  4TJW A;  4UX4 A;  5FH2 A;  2PQF A;  1OS1 A;  1K3C A;  4PAX A;  2PXZ X;  4L0I A;  4GMU A;  5FPG A;  5DCZ A;  4YWD A;  3UA9 A;  4UFY A;  4MT9 A;  1PAX A;  3DT2 A;  2RK7 A;  5ADR A;  3U9Y A; 
#chains in the Genus database with same CATH homology
 2X5Y A;  5FH1 A;  4HKI A;  4L32 A;  4UI8 A;  1KHE A;  4L7P A;  4GMZ A;  2RF5 A;  5AL5 A;  2OLR A;  5C5P A;  4BJC A;  1KHB A;  4HL5 A;  4W5I A;  4R6E A;  3P0P A;  4BUI A;  4HMH A;  4RV6 A;  4UVZ A;  3MHJ A;  3L3M A;  4HLF A;  1UK0 A;  1XKV A;  4UI5 A;  1AYL A;  4GMW A;  4PNS A;  3MOE A;  4YW9 A;  5AEH A;  4L7O A;  5AKU A;  5ECE A;  4BS4 A;  3GOY A;  5FPF A;  4W6E A;  4AVW A;  4I9I A;  4L31 A;  4PNM A;  4BUT A;  3KR7 A;  5FH4 A;  4GV2 A;  4OQA C;  3UH2 A;  1YGG A;  4GMM A;  4L10 A;  4HKK A;  4UFU A;  4BUY A;  4BJ9 A;  2RD6 A;  3UDD A;  4UVU A;  1GS0 A;  3C4H A;  4TK5 A;  2PY7 X;  4TOR A;  4UUH A;  4PNL A;  2PC9 A;  4BU3 A;  4TK0 A;  4R5W A;  4L34 A;  4KZL A;  4HKN A;  3P0N A;  4BUW A;  4HLM A;  4UVT A;  5ADS A;  3C49 A;  4OX2 A;  4L7L A;  4UVW A;  2QEW A;  5LXP A;  5LYH A;  3L3L A;  4N4V A;  4UHG A;  2ZCI A;  4BU7 A;  4J21 A;  2RKE A;  4WIE A;  4BUD A;  2OLQ A;  2FAH A;  4L0T A;  4N3R A;  4L6S A;  4F0E A;  4L7U A;  4PY4 A;  3W51 A;  4YWB A;  4BU5 A;  1YLH A;  4UVP A;  4UVL A;  4BFP A;  3DTB A;  4GNM A;  4L0V A;  5C5Q A;  4RCG A;  3U9H A;  4BUS A;  2RCW A;  5AL1 A;  4MSK A;  4XHU A;  4TKI A;  1OEN A;  5EBT A;  3P0Q A;  4F1Q A;  4BUA A;  3PAX A;  4OA7 A;  4OQB C;  4L7R A;  3SE2 A;  4GNP A;  4HHY A;  4IUE A;  4PNN A;  4U6A A;  4BUX A;  4J22 A;  4UVN A;  1WOK A;  4LI7 A;  4TJU A;  4TOS A;  1J3B A;  4WL8 A;  4UI7 A;  5LX6 A;  4J1Z A;  4LI8 A;  1NHX A;  4L0S A;  4WPT A;  2PAW A;  4L33 A;  3KR8 A;  4UVO A;  4X52 A;  5FH0 A;  3BLJ A;  4WPU A;  4GV0 A;  4L0B A;  4L09 A;  5ETY A;  4AVU A;  3CE0 A;  3KCZ A;  5FH3 A;  2RKA A;  1KHG A;  4TJY A;  4L7N A;  2QEY A;  4WOU A;  4TKF A;  5AL3 A;  4YW8 A;  1UK1 A;  4KZU A;  4F1L A;  4K4F A;  4BUF A;  2RKD A;  4PML A;  1AQ2 A;  4K4E A;  4GV7 A;  4PNR A;  3MOH A;  4MSG A;  4W5S A;  4UI6 A;  4L70 A;  2QF2 A;  3MHK A;  4UVY A;  4ZZX A;  2PAX A;  5I67 A;  4LI6 A;  4M7B A;  3SMJ A;  4BUV A;  4PJT A;  1A26 A;  5C5R A;  1K3D A;  3GN7 A;  4KZQ A;  4PNT A;  4R43 A;  5AL4 A;  3DT7 A;  1EFY A;  4HLH A;  4GNQ A;  4ZZZ A;  4OPX C;  4HLG A;  4UND A;  4PNQ A;  4L2F A;  4L2G A;  4TJW A;  4UX4 A;  5FH2 A;  4UW1 A;  2PQF A;  4UI3 A;  1KHF A;  3GJW A;  4BU8 A;  2FAF A;  3KJD A;  3DT4 A;  4UVX A;  2GMV A;  5AKW A;  1OS1 A;  4DVI A;  1K3C A;  4GNO A;  4J3L A;  4PAX A;  4UXB A;  4ZZY A;  2PXZ X;  4KRS A;  4GMU A;  4L0I A;  4L2K A;  4HHZ A;  3HKV A;  5FH5 A;  4N4T A;  5A00 A;  5FPG A;  1YVY A;  5AL2 A;  4BUU A;  3SMI A;  3FHB A;  4J3M A;  5DCZ A;  4BU9 A;  4HLK A;  4L6Z A;  4BUE A;  4BU6 A;  4PJV A;  4YWD A;  3UA9 A;  4WIU A;  4UFY A;  4UVV A;  1M51 A;  4BJB A;  3MOF A;  2RK8 A;  4GNL A;  4UI4 A;  3GEY A;  4MT9 A;  4DQY C;  4UVS A;  4TVJ A;  2QZY A;  5ADT A;  1II2 A;  1PAX A;  3DT2 A;  2RK7 A;  4HYF A;  3UH4 A;  4WPV A;  4GV4 A;  5ADR A;  3U9Y A;  2QF1 A;  4TKG A;  5ADQ A;  1YTM A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4RV6A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations