4X8YA

Crystal structure of human pgrmc1 cytochrome b5-like domain
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
112
structure length
112
Chain Sequence
SPEFDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords Membrane-associated progesterone receptor component 1
total genus 33
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00173 Cyt-b5 Cytochrome b5-like Heme/Steroid binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.120.10 Alpha Beta Roll Flavocytochrome B2; Chain A, domain 1 Cytochrome b5-like heme/steroid binding domain 4x8yA00
3X33A 1I8CA 1FCBA 1BLVA 1F03A 1M59A 1ES1A 1LQXA 1NX7A 3LF5A 1J03A 1J0QA 1LCOA 1F04A 1LDCA 1I87A 4HINA 2I89A 1LR6A 1KBIA 4B8NA 1AXXA 1IEUA 1IB7A 2KEOA 1M20A 1MNYA 2AXXA 1T0GA 2I96A 1SOXA 1MJ4A 3KS0A 1SH4A 1IETA 2IBJA 1U9UA 2OZ0A 1U9MA 1BFXA 1AQAA 1M2MA 3X35A 3X32A 1JEXA 1EHBA 1LTDA 1B5MA 4X8YA 3OZZB 3X34A 1CXYA 1DO9A 1AWPA 1EUEA 1LJ0A 1B5BA 1M2IA 3MUSA 4HILA 1X3XA 3NERA 1I5UA 1AW3A 1ICCA 1CYOA 1B5AA 1HKOA 2M33A
chains in the Genus database with same CATH superfamily
3X33A 1I8CA 1FCBA 1BLVA 1F03A 1M59A 1ES1A 1LQXA 1NX7A 3LF5A 1J03A 1J0QA 1LCOA 1F04A 1LDCA 1I87A 4HINA 2I89A 1LR6A 1KBIA 4B8NA 1AXXA 1IEUA 1IB7A 2KEOA 1M20A 1MNYA 2AXXA 1T0GA 2I96A 1SOXA 1MJ4A 3KS0A 1SH4A 1IETA 2IBJA 1U9UA 2OZ0A 1U9MA 1BFXA 1AQAA 1M2MA 3X35A 3X32A 1JEXA 1EHBA 1LTDA 1B5MA 4X8YA 3OZZB 3X34A 1CXYA 1DO9A 1AWPA 1EUEA 1LJ0A 1B5BA 1M2IA 3MUSA 4HILA 1X3XA 3NERA 1I5UA 1AW3A 1ICCA 1CYOA 1B5AA 1HKOA 2M33A
chains in the Genus database with same CATH topology
3X33A 1I8CA 1FCBA 1BLVA 1F03A 1M59A 1ES1A 1LQXA 1NX7A 3LF5A 1J03A 1J0QA 1LCOA 1F04A 1LDCA 1I87A 4HINA 2I89A 1LR6A 1KBIA 4B8NA 1AXXA 1IEUA 1IB7A 2KEOA 1M20A 1MNYA 2AXXA 1T0GA 2I96A 1SOXA 1MJ4A 3KS0A 1SH4A 1IETA 2IBJA 1U9UA 2OZ0A 1U9MA 1BFXA 1AQAA 1M2MA 3X35A 3X32A 1JEXA 1EHBA 1LTDA 1B5MA 4X8YA 3OZZB 3X34A 1CXYA 1DO9A 1AWPA 1EUEA 1LJ0A 1B5BA 1M2IA 3MUSA 4HILA 1X3XA 3NERA 1I5UA 1AW3A 1ICCA 1CYOA 1B5AA 1HKOA 2M33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X33 A;  1I8C A;  1FCB A;  1BLV A;  1F03 A;  1M59 A;  1ES1 A;  1LQX A;  1NX7 A;  3LF5 A;  1J03 A;  1J0Q A;  1LCO A;  1F04 A;  1LDC A;  1I87 A;  4HIN A;  2I89 A;  1LR6 A;  1KBI A;  4B8N A;  1AXX A;  1IEU A;  1IB7 A;  2KEO A;  1M20 A;  1MNY A;  2AXX A;  1T0G A;  2I96 A;  1SOX A;  1MJ4 A;  3KS0 A;  1SH4 A;  1IET A;  2IBJ A;  1U9U A;  2OZ0 A;  1U9M A;  1BFX A;  1AQA A;  1M2M A;  3X35 A;  3X32 A;  1JEX A;  1EHB A;  1LTD A;  1B5M A;  4X8Y A;  3OZZ B;  3X34 A;  1CXY A;  1DO9 A;  1AWP A;  1EUE A;  1LJ0 A;  1B5B A;  1M2I A;  3MUS A;  4HIL A;  1X3X A;  3NER A;  1I5U A;  1AW3 A;  1ICC A;  1CYO A;  1B5A A;  1HKO A;  2M33 A; 
#chains in the Genus database with same CATH topology
 3X33 A;  1I8C A;  1FCB A;  1BLV A;  1F03 A;  1M59 A;  1ES1 A;  1LQX A;  1NX7 A;  3LF5 A;  1J03 A;  1J0Q A;  1LCO A;  1F04 A;  1LDC A;  1I87 A;  4HIN A;  2I89 A;  1LR6 A;  1KBI A;  4B8N A;  1AXX A;  1IEU A;  1IB7 A;  2KEO A;  1M20 A;  1MNY A;  2AXX A;  1T0G A;  2I96 A;  1SOX A;  1MJ4 A;  3KS0 A;  1SH4 A;  1IET A;  2IBJ A;  1U9U A;  2OZ0 A;  1U9M A;  1BFX A;  1AQA A;  1M2M A;  3X35 A;  3X32 A;  1JEX A;  1EHB A;  1LTD A;  1B5M A;  4X8Y A;  3OZZ B;  3X34 A;  1CXY A;  1DO9 A;  1AWP A;  1EUE A;  1LJ0 A;  1B5B A;  1M2I A;  3MUS A;  4HIL A;  1X3X A;  3NER A;  1I5U A;  1AW3 A;  1ICC A;  1CYO A;  1B5A A;  1HKO A;  2M33 A; 
#chains in the Genus database with same CATH homology
 3X33 A;  1I8C A;  1FCB A;  1BLV A;  1F03 A;  1M59 A;  1ES1 A;  1LQX A;  1NX7 A;  3LF5 A;  1J03 A;  1J0Q A;  1LCO A;  1F04 A;  1LDC A;  1I87 A;  4HIN A;  2I89 A;  1LR6 A;  1KBI A;  4B8N A;  1AXX A;  1IEU A;  1IB7 A;  2KEO A;  1M20 A;  1MNY A;  2AXX A;  1T0G A;  2I96 A;  1SOX A;  1MJ4 A;  3KS0 A;  1SH4 A;  1IET A;  2IBJ A;  1U9U A;  2OZ0 A;  1U9M A;  1BFX A;  1AQA A;  1M2M A;  3X35 A;  3X32 A;  1JEX A;  1EHB A;  1LTD A;  1B5M A;  4X8Y A;  3OZZ B;  3X34 A;  1CXY A;  1DO9 A;  1AWP A;  1EUE A;  1LJ0 A;  1B5B A;  1M2I A;  3MUS A;  4HIL A;  1X3X A;  3NER A;  1I5U A;  1AW3 A;  1ICC A;  1CYO A;  1B5A A;  1HKO A;  2M33 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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