4ZZZA

Structure of human parp1 catalytic domain bound to an isoindolinone inhibitor
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
353
structure length
350
Chain Sequence
KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords POLY [ADP-RIBOSE] POLYMERASE 1
publication title Discovery of 2-[1-(4,4-Difluorocyclohexyl)Piperidin-4-Yl]-6-Fluoro-3-Oxo-2,3-Dihydro-1H-Isoindole-4-Carboxamide (Nms-P118): A Potent, Orally Available and Highly Selective Parp- 1 Inhibitor for Cancer Therapy.
pubmed doi rcsb
source organism Homo sapiens
total genus 113
structure length 350
sequence length 353
chains with identical sequence B
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00644 PARP Poly(ADP-ribose) polymerase catalytic domain
A PF02877 PARP_reg Poly(ADP-ribose) polymerase, regulatory domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.142.10 Mainly Alpha Up-down Bundle Poly(ADP-ribose) Polymerase; domain 1 Poly(ADP-ribose) polymerase, regulatory domain 4zzzA01
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 4zzzA02
4K4EA 4LI7A 4BS4A 4UFUA 4UHGA 4LI6A 5DCZA 4TOSA 2PAWA 4KZUA 4PNQA 4F1QA 4UUHA 2PQFA 2RF5A 4L0VA 4LI8A 4PMLA 4ZZYA 4PNLA 5ECEA 4ZZXA 3U9YA 4L2FA 4BU6A 2PAXA 4BJ9A 4PJTA 3C4HA 4W5IA 4PNRA 3HKVA 4BU3A 4L0TA 4X52A 4HKNA 5AEHA 3MHJA 5A00A 4TORA 4MT9A 4KZQA 4OPXC 4L7UA 4OQBC 4L34A 5AL2A 1UK1A 4UVYA 4TVJA 1WOKA 4J3MA 4U6AA 5AKWA 4TJYA 4L7OA 4TK0A 3P0NA 4UVPA 4BUIA 4UVSA 4UVVA 3CE0A 4HMHA 3SE2A 4DVIA 4HHYA 4W6EA 4L31A 4GV4A 4TKGA 4RV6A 4UI7A 3KR7A 4HKIA 2RCWA 4PNMA 4BUYA 4OA7A 4KRSA 4BU8A 4UI4A 4L0SA 4IUEA 3L3MA 3UDDA 4UVNA 4HLGA 4M7BA 4MSGA 4TJWA 5AL3A 4BJCA 4GV2A 4UX4A 3P0QA 4HLHA 4UVOA 3KR8A 4PNSA 4UVWA 4UXBA 3GN7A 5ETYA 4BUVA 3GJWA 4L7PA 5LX6A 3FHBA 4AVUA 5C5PA 3W51A 4TKIA 5AL1A 4L7RA 4OQAC 4F0EA 4HLFA 5AL4A 4PNNA 4J1ZA 4HLMA 3UH4A 4L10A 4XHUA 5EBTA 1EFYA 4R5WA 4L6SA 4N4VA 3SMIA 4HYFA 4BJBA 4KZLA 4UNDA 4UVZA 3KJDA 4BU5A 4BUTA 4UI5A 1GS0A 3GOYA 4J21A 4BUAA 4L2GA 3PAXA 4R6EA 4HLKA 4MSKA 1UK0A 4L2KA 4BUEA 4L7NA 4I9IA 3KCZA 5AKUA 4L0BA 4GV7A 4TJUA 4UVUA 4BUWA 3BLJA 4PJVA 4HL5A 4TK5A 1A26A 4UI6A 4BUSA 3GEYA 4ZZZA 4BUDA 3C49A 4UW1A 3SMJA 4HHZA 5FPFA 4UVTA 4DQYC 4N4TA 5C5RA 5ADQA 3UA9A 4L6ZA 4BFPA 3MHKA 4J22A 4BU9A 1PAXA 4UVXA 3P0PA 4AVWA 4K4FA 4UI8A 5AL5A 5C5QA 5ADSA 4N3RA 4BUXA 4L33A 4PY4A 4HKKA 4BUFA 4PNTA 4L09A 4UI3A 4TKFA 4L0IA 3UH2A 5ADTA 4L70A 5FPGA 3U9HA 4F1LA 2X5YA 4L7LA 5LYHA 4PAXA 4GV0A 4L32A 4W5SA 4J3LA 4UVLA 5ADRA 3L3LA 4UFYA 4BUUA 4BU7A 2RD6A 5LXPA
chains in the Genus database with same CATH superfamily
2PC9A 4LI7A 4BS4A 4WPUA 4TOSA 2RK8A 4PMLA 4LI8A 4ZZYA 4BU6A 3C4HA 4PNRA 5A00A 4OQBC 4TVJA 1WOKA 4J3MA 3P0NA 4BUIA 3CE0A 4HMHA 1YVYA 4GV4A 4TKGA 4UI7A 4PNMA 4OA7A 4J1GA 4HLHA 4PNSA 5ETYA 4L7PA 4AVUA 3W51A 2RKDA 4F0EA 5FH5A 4PNNA 3UH4A 4L10A 4N4VA 4HYFA 4BU5A 3MOHA 4J21A 3PAXA 2RKAA 4HLKA 3KCZA 1OS1A 1A26A 3DT4A 4UI6A 4BUSA 3GEYA 1YGGA 5FPFA 4UVTA 5ADQA 5C5RA 4BFPA 3MHKA 1PAXA 4L33A 4PY4A 4HKKA 4TKFA 4JNGA 2X5YA 4GNMA 4L32A 1K3CA 4X52A 4LI6A 2PAWA 4PNQA 4L2FA 4BJ9A 4W5IA 2PXZX 4BU3A 5AEHA 3MHJA 4MT9A 1UK1A 4UVYA 1M51A 4L7OA 4R43A 5FH0A 4UVSA 4UVVA 4HKIA 2RCWA 4KRSA 4WPTA 4IUEA 3L3MA 3MOEA 3UDDA 4IDUA 1KHEA 4MSGA 4TJWA 4BJCA 4UX4A 3ZL9A 1K3DA 3P0QA 4UVOA 4BUVA 5C5PA 4BHHB 4TKIA 4L7RA 4YW8A 4HLFA 5AL4A 4WOUA 1NHXA 4XHUA 1EFYA 4R5WA 2OLRA 4BJBA 4KZLA 4UNDA 4BGPA 3DTBA 4L2KA 4L7NA 4I9IA 4UVUA 3BLJA 1YLHA 4PJVA 1J3BA 4TK5A 4ZZZA 4BUDA 3C49A 4RCGA 3UA9A 4J22A 1XKVA 3P0PA 2ZCIA 4K4FA 5AL5A 4L09A 2RKEA 5FH2A 3UH2A 5ADTA 4L70A 5FPGA 4F1LA 4L7LA 4GV0A 3DT7A 1AQ2A 4J3LA 3L3LA 4UFYA 4BUUA 5LXPA 4IJSA 2QF2A 4KZUA 4PNLA 4ZZXA 2OLQA 2QZYA 4PJTA 3MOFA 4L0TA 4HKNA 1KHFA 2QEYA 4TORA 4OPXC 4GMZA 5AL2A 5FH1A 4U6AA 5AKWA 4TJYA 4TK0A 4UVPA 4DVIA 4HHYA 4L31A 3KR7A 4UI4A 4L0SA 4GMWA 4UVNA 4HLGA 4GNOA 5AL3A 4GV2A 1OENA 3KR8A 2RK7A 5FH3A 5LX6A 4IDXA 3FHBA 4WL8A 1AYLA 4J1ZA 4HLMA 5I67A 3SMIA 4BUAA 4IDUB 4UVZA 1KHBA 4MSKA 1II2A 4YWDA 5AKUA 4L0BA 4TJUA 4BUWA 4HL5A 4GNQA 2PY7X 3ZLAA 4BU9A 4UVXA 5ADSA 4N3RA 4BUFA 4UI3A 4YWBA 5LYHA 4PAXA 4GMMA 5ADRA 2FAFA 2RD6A 4K4EA 4UFUA 1KHGA 4UHGA 5DCZA 4F1QA 4UUHA 2PQFA 2RF5A 4L0VA 3U9YA 5ECEA 2PAXA 3HKVA 4KZQA 4L7UA 4L34A 4GNLA 3DT2A 4GMUA 3SE2A 4W6EA 4RV6A 4BUYA 4BU8A 4WIEA 2FAHA 4M7BA 4YW9A 4UVWA 4UXBA 3GN7A 3GJWA 4GNPA 5AL1A 4OX2A 4OQAC 2QF1A 5EBTA 4L6SA 3KJDA 4WIUA 5FH4A 4UI5A 1GS0A 4BUTA 3GOYA 2QEWA 4L2GA 4R6EA 1UK0A 4BUEA 4WPVA 4GV7A 3SMJA 4UW1A 4HHZA 4DQYC 4N4TA 4L6ZA 4AVWA 4UI8A 5C5QA 4BUXA 4PNTA 1YTMA 4L0IA 2GMVA 3U9HA 4J1JA 4W5SA 4UVLA 4BU7A
chains in the Genus database with same CATH topology
4K4EA 2PC9A 4LI7A 4BS4A 4WPUA 2QF2A 4UFUA 1KHGA 4UHGA 4LI6A 5DCZA 4TOSA 2PAWA 4KZUA 4PNQA 4F1QA 4UUHA 2PQFA 2RK8A 2RF5A 4L0VA 4LI8A 4PMLA 4ZZYA 4PNLA 5ECEA 4ZZXA 3U9YA 4L2FA 4BU6A 2OLQA 2PAXA 2QZYA 4BJ9A 4PJTA 3C4HA 4W5IA 2PXZX 3MOFA 4PNRA 3HKVA 4BU3A 4L0TA 4X52A 4HKNA 5AEHA 3MHJA 1KHFA 5A00A 2QEYA 4MT9A 4TORA 4KZQA 4OPXC 4L7UA 4OQBC 4L34A 4GMZA 5AL2A 1UK1A 4UVYA 4TVJA 5FH1A 1M51A 1WOKA 4J3MA 4U6AA 5AKWA 4GNLA 4TJYA 4L7OA 4TK0A 3DT2A 3P0NA 4GMUA 4R43A 4UVVA 3CE0A 4HMHA 1YVYA 4UVSA 4UVPA 5FH0A 3SE2A 4DVIA 4HHYA 4W6EA 4L31A 4GV4A 4TKGA 4RV6A 4UI7A 3KR7A 4HKIA 2RCWA 4PNMA 4BUYA 4OA7A 4KRSA 4WPTA 4BU8A 4UI4A 4L0SA 4IUEA 3SMIA 3L3MA 3MOEA 3UDDA 4GMWA 4UVNA 4WIEA 4HLGA 1KHEA 2FAHA 4M7BA 4GNOA 4MSGA 4TJWA 5AL3A 4BJCA 4GV2A 4UX4A 1OENA 4YW9A 1K3DA 3P0QA 4HLHA 3KR8A 4PNSA 4UVWA 4UVOA 4UXBA 3GN7A 5ETYA 4BUVA 2RK7A 3GJWA 4L7PA 5FH3A 5LX6A 4BUIA 3FHBA 4AVUA 4GNPA 5C5PA 3W51A 4TKIA 4WL8A 5AL1A 1AYLA 4L7RA 4OX2A 4YW8A 2RKDA 4OQAC 4F0EA 2QF1A 5FH5A 4HLFA 5AL4A 4PNNA 4WOUA 4J1ZA 4HLMA 3UH4A 5I67A 1NHXA 4XHUA 4L10A 1EFYA 4R5WA 4L6SA 2OLRA 4N4VA 4HYFA 5EBTA 4KZLA 4UNDA 4UVZA 3KJDA 4BJBA 4BU5A 4WIUA 5FH4A 4UI5A 1GS0A 1KHBA 3GOYA 3MOHA 4J21A 4BUTA 4BUAA 2QEWA 4L2GA 3PAXA 2RKAA 4R6EA 3DTBA 4HLKA 4MSKA 1UK0A 4L2KA 1II2A 4L7NA 4I9IA 4YWDA 4BUEA 4WPVA 3KCZA 5AKUA 4L0BA 4GV7A 4TJUA 1OS1A 4UVUA 4BUWA 3BLJA 1YLHA 4PJVA 1J3BA 4HL5A 4TK5A 1A26A 3DT4A 4UI6A 4BUSA 3GEYA 4ZZZA 4BUDA 3C49A 4UW1A 3SMJA 4HHZA 1YGGA 5FPFA 4UVTA 4DQYC 4GNQA 4N4TA 5C5RA 4RCGA 5ADQA 2PY7X 3UA9A 4L6ZA 4BFPA 3MHKA 1XKVA 4J22A 1PAXA 4UVXA 3P0PA 4BU9A 4AVWA 2ZCIA 4K4FA 4UI8A 5AL5A 5C5QA 5ADSA 4N3RA 4BUXA 4L33A 4PY4A 4HKKA 4BUFA 4PNTA 4L09A 2RKEA 5FH2A 4UI3A 4TKFA 1YTMA 4L0IA 3UH2A 5ADTA 2GMVA 4L70A 5FPGA 3U9HA 4YWBA 2X5YA 4F1LA 4L7LA 5LYHA 4PAXA 4GV0A 4GNMA 4L32A 4W5SA 3DT7A 4GMMA 4J3LA 1AQ2A 4UVLA 1K3CA 5ADRA 2FAFA 3L3LA 4UFYA 4BUUA 4BU7A 2RD6A 5LXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K4E A;  4LI7 A;  4BS4 A;  4UFU A;  4UHG A;  4LI6 A;  5DCZ A;  4TOS A;  2PAW A;  4KZU A;  4PNQ A;  4F1Q A;  4UUH A;  2PQF A;  2RF5 A;  4L0V A;  4LI8 A;  4PML A;  4ZZY A;  4PNL A;  5ECE A;  4ZZX A;  3U9Y A;  4L2F A;  4BU6 A;  2PAX A;  4BJ9 A;  4PJT A;  3C4H A;  4W5I A;  4PNR A;  3HKV A;  4BU3 A;  4L0T A;  4X52 A;  4HKN A;  5AEH A;  3MHJ A;  5A00 A;  4TOR A;  4MT9 A;  4KZQ A;  4OPX C;  4L7U A;  4OQB C;  4L34 A;  5AL2 A;  1UK1 A;  4UVY A;  4TVJ A;  1WOK A;  4J3M A;  4U6A A;  5AKW A;  4TJY A;  4L7O A;  4TK0 A;  3P0N A;  4UVP A;  4BUI A;  4UVS A;  4UVV A;  3CE0 A;  4HMH A;  3SE2 A;  4DVI A;  4HHY A;  4W6E A;  4L31 A;  4GV4 A;  4TKG A;  4RV6 A;  4UI7 A;  3KR7 A;  4HKI A;  2RCW A;  4PNM A;  4BUY A;  4OA7 A;  4KRS A;  4BU8 A;  4UI4 A;  4L0S A;  4IUE A;  3L3M A;  3UDD A;  4UVN A;  4HLG A;  4M7B A;  4MSG A;  4TJW A;  5AL3 A;  4BJC A;  4GV2 A;  4UX4 A;  3P0Q A;  4HLH A;  4UVO A;  3KR8 A;  4PNS A;  4UVW A;  4UXB A;  3GN7 A;  5ETY A;  4BUV A;  3GJW A;  4L7P A;  5LX6 A;  3FHB A;  4AVU A;  5C5P A;  3W51 A;  4TKI A;  5AL1 A;  4L7R A;  4OQA C;  4F0E A;  4HLF A;  5AL4 A;  4PNN A;  4J1Z A;  4HLM A;  3UH4 A;  4L10 A;  4XHU A;  5EBT A;  1EFY A;  4R5W A;  4L6S A;  4N4V A;  3SMI A;  4HYF A;  4BJB A;  4KZL A;  4UND A;  4UVZ A;  3KJD A;  4BU5 A;  4BUT A;  4UI5 A;  1GS0 A;  3GOY A;  4J21 A;  4BUA A;  4L2G A;  3PAX A;  4R6E A;  4HLK A;  4MSK A;  1UK0 A;  4L2K A;  4BUE A;  4L7N A;  4I9I A;  3KCZ A;  5AKU A;  4L0B A;  4GV7 A;  4TJU A;  4UVU A;  4BUW A;  3BLJ A;  4PJV A;  4HL5 A;  4TK5 A;  1A26 A;  4UI6 A;  4BUS A;  3GEY A;  4ZZZ A;  4BUD A;  3C49 A;  4UW1 A;  3SMJ A;  4HHZ A;  5FPF A;  4UVT A;  4DQY C;  4N4T A;  5C5R A;  5ADQ A;  3UA9 A;  4L6Z A;  4BFP A;  3MHK A;  4J22 A;  4BU9 A;  1PAX A;  4UVX A;  3P0P A;  4AVW A;  4K4F A;  4UI8 A;  5AL5 A;  5C5Q A;  5ADS A;  4N3R A;  4BUX A;  4L33 A;  4PY4 A;  4HKK A;  4BUF A;  4PNT A;  4L09 A;  4UI3 A;  4TKF A;  4L0I A;  3UH2 A;  5ADT A;  4L70 A;  5FPG A;  3U9H A;  4F1L A;  2X5Y A;  4L7L A;  5LYH A;  4PAX A;  4GV0 A;  4L32 A;  4W5S A;  4J3L A;  4UVL A;  5ADR A;  3L3L A;  4UFY A;  4BUU A;  4BU7 A;  2RD6 A;  5LXP A; 
#chains in the Genus database with same CATH topology
 2PC9 A;  4LI7 A;  4BS4 A;  4WPU A;  4TOS A;  2RK8 A;  4PML A;  4LI8 A;  4ZZY A;  4BU6 A;  3C4H A;  4PNR A;  5A00 A;  4OQB C;  4TVJ A;  1WOK A;  4J3M A;  3P0N A;  4BUI A;  3CE0 A;  4HMH A;  1YVY A;  4GV4 A;  4TKG A;  4UI7 A;  4PNM A;  4OA7 A;  4J1G A;  4HLH A;  4PNS A;  5ETY A;  4L7P A;  4AVU A;  3W51 A;  2RKD A;  4F0E A;  5FH5 A;  4PNN A;  3UH4 A;  4L10 A;  4N4V A;  4HYF A;  4BU5 A;  3MOH A;  4J21 A;  3PAX A;  2RKA A;  4HLK A;  3KCZ A;  1OS1 A;  1A26 A;  3DT4 A;  4UI6 A;  4BUS A;  3GEY A;  1YGG A;  5FPF A;  4UVT A;  5ADQ A;  5C5R A;  4BFP A;  3MHK A;  1PAX A;  4L33 A;  4PY4 A;  4HKK A;  4TKF A;  4JNG A;  2X5Y A;  4GNM A;  4L32 A;  1K3C A;  4X52 A;  4LI6 A;  2PAW A;  4PNQ A;  4L2F A;  4BJ9 A;  4W5I A;  2PXZ X;  4BU3 A;  5AEH A;  3MHJ A;  4MT9 A;  1UK1 A;  4UVY A;  1M51 A;  4L7O A;  4R43 A;  5FH0 A;  4UVS A;  4UVV A;  4HKI A;  2RCW A;  4KRS A;  4WPT A;  4IUE A;  3L3M A;  3MOE A;  3UDD A;  4IDU A;  1KHE A;  4MSG A;  4TJW A;  4BJC A;  4UX4 A;  3ZL9 A;  1K3D A;  3P0Q A;  4UVO A;  4BUV A;  5C5P A;  4BHH B;  4TKI A;  4L7R A;  4YW8 A;  4HLF A;  5AL4 A;  4WOU A;  1NHX A;  4XHU A;  1EFY A;  4R5W A;  2OLR A;  4BJB A;  4KZL A;  4UND A;  4BGP A;  3DTB A;  4L2K A;  4L7N A;  4I9I A;  4UVU A;  3BLJ A;  1YLH A;  4PJV A;  1J3B A;  4TK5 A;  4ZZZ A;  4BUD A;  3C49 A;  4RCG A;  3UA9 A;  4J22 A;  1XKV A;  3P0P A;  2ZCI A;  4K4F A;  5AL5 A;  4L09 A;  2RKE A;  5FH2 A;  3UH2 A;  5ADT A;  4L70 A;  5FPG A;  4F1L A;  4L7L A;  4GV0 A;  3DT7 A;  1AQ2 A;  4J3L A;  3L3L A;  4UFY A;  4BUU A;  5LXP A;  4IJS A;  2QF2 A;  4KZU A;  4PNL A;  4ZZX A;  2OLQ A;  2QZY A;  4PJT A;  3MOF A;  4L0T A;  4HKN A;  1KHF A;  2QEY A;  4TOR A;  4OPX C;  4GMZ A;  5AL2 A;  5FH1 A;  4U6A A;  5AKW A;  4TJY A;  4TK0 A;  4UVP A;  4DVI A;  4HHY A;  4L31 A;  3KR7 A;  4UI4 A;  4L0S A;  4GMW A;  4UVN A;  4HLG A;  4GNO A;  5AL3 A;  4GV2 A;  1OEN A;  3KR8 A;  2RK7 A;  5FH3 A;  5LX6 A;  4IDX A;  3FHB A;  4WL8 A;  1AYL A;  4J1Z A;  4HLM A;  5I67 A;  3SMI A;  4BUA A;  4IDU B;  4UVZ A;  1KHB A;  4MSK A;  1II2 A;  4YWD A;  5AKU A;  4L0B A;  4TJU A;  4BUW A;  4HL5 A;  4GNQ A;  2PY7 X;  3ZLA A;  4BU9 A;  4UVX A;  5ADS A;  4N3R A;  4BUF A;  4UI3 A;  4YWB A;  5LYH A;  4PAX A;  4GMM A;  5ADR A;  2FAF A;  2RD6 A;  4K4E A;  4UFU A;  1KHG A;  4UHG A;  5DCZ A;  4F1Q A;  4UUH A;  2PQF A;  2RF5 A;  4L0V A;  3U9Y A;  5ECE A;  2PAX A;  3HKV A;  4KZQ A;  4L7U A;  4L34 A;  4GNL A;  3DT2 A;  4GMU A;  3SE2 A;  4W6E A;  4RV6 A;  4BUY A;  4BU8 A;  4WIE A;  2FAH A;  4M7B A;  4YW9 A;  4UVW A;  4UXB A;  3GN7 A;  3GJW A;  4GNP A;  5AL1 A;  4OX2 A;  4OQA C;  2QF1 A;  5EBT A;  4L6S A;  3KJD A;  4WIU A;  5FH4 A;  4UI5 A;  1GS0 A;  4BUT A;  3GOY A;  2QEW A;  4L2G A;  4R6E A;  1UK0 A;  4BUE A;  4WPV A;  4GV7 A;  3SMJ A;  4UW1 A;  4HHZ A;  4DQY C;  4N4T A;  4L6Z A;  4AVW A;  4UI8 A;  5C5Q A;  4BUX A;  4PNT A;  1YTM A;  4L0I A;  2GMV A;  3U9H A;  4J1J A;  4W5S A;  4UVL A;  4BU7 A; 
#chains in the Genus database with same CATH homology
 4K4E A;  2PC9 A;  4LI7 A;  4BS4 A;  4WPU A;  2QF2 A;  4UFU A;  1KHG A;  4UHG A;  4LI6 A;  5DCZ A;  4TOS A;  2PAW A;  4KZU A;  4PNQ A;  4F1Q A;  4UUH A;  2PQF A;  2RK8 A;  2RF5 A;  4L0V A;  4LI8 A;  4PML A;  4ZZY A;  4PNL A;  5ECE A;  4ZZX A;  3U9Y A;  4L2F A;  4BU6 A;  2OLQ A;  2PAX A;  2QZY A;  4BJ9 A;  4PJT A;  3C4H A;  4W5I A;  2PXZ X;  3MOF A;  4PNR A;  3HKV A;  4BU3 A;  4L0T A;  4X52 A;  4HKN A;  5AEH A;  3MHJ A;  1KHF A;  5A00 A;  2QEY A;  4MT9 A;  4TOR A;  4KZQ A;  4OPX C;  4L7U A;  4OQB C;  4L34 A;  4GMZ A;  5AL2 A;  1UK1 A;  4UVY A;  4TVJ A;  5FH1 A;  1M51 A;  1WOK A;  4J3M A;  4U6A A;  5AKW A;  4GNL A;  4TJY A;  4L7O A;  4TK0 A;  3DT2 A;  3P0N A;  4GMU A;  4R43 A;  4UVV A;  3CE0 A;  4HMH A;  1YVY A;  4UVS A;  4UVP A;  5FH0 A;  3SE2 A;  4DVI A;  4HHY A;  4W6E A;  4L31 A;  4GV4 A;  4TKG A;  4RV6 A;  4UI7 A;  3KR7 A;  4HKI A;  2RCW A;  4PNM A;  4BUY A;  4OA7 A;  4KRS A;  4WPT A;  4BU8 A;  4UI4 A;  4L0S A;  4IUE A;  3SMI A;  3L3M A;  3MOE A;  3UDD A;  4GMW A;  4UVN A;  4WIE A;  4HLG A;  1KHE A;  2FAH A;  4M7B A;  4GNO A;  4MSG A;  4TJW A;  5AL3 A;  4BJC A;  4GV2 A;  4UX4 A;  1OEN A;  4YW9 A;  1K3D A;  3P0Q A;  4HLH A;  3KR8 A;  4PNS A;  4UVW A;  4UVO A;  4UXB A;  3GN7 A;  5ETY A;  4BUV A;  2RK7 A;  3GJW A;  4L7P A;  5FH3 A;  5LX6 A;  4BUI A;  3FHB A;  4AVU A;  4GNP A;  5C5P A;  3W51 A;  4TKI A;  4WL8 A;  5AL1 A;  1AYL A;  4L7R A;  4OX2 A;  4YW8 A;  2RKD A;  4OQA C;  4F0E A;  2QF1 A;  5FH5 A;  4HLF A;  5AL4 A;  4PNN A;  4WOU A;  4J1Z A;  4HLM A;  3UH4 A;  5I67 A;  1NHX A;  4XHU A;  4L10 A;  1EFY A;  4R5W A;  4L6S A;  2OLR A;  4N4V A;  4HYF A;  5EBT A;  4KZL A;  4UND A;  4UVZ A;  3KJD A;  4BJB A;  4BU5 A;  4WIU A;  5FH4 A;  4UI5 A;  1GS0 A;  1KHB A;  3GOY A;  3MOH A;  4J21 A;  4BUT A;  4BUA A;  2QEW A;  4L2G A;  3PAX A;  2RKA A;  4R6E A;  3DTB A;  4HLK A;  4MSK A;  1UK0 A;  4L2K A;  1II2 A;  4L7N A;  4I9I A;  4YWD A;  4BUE A;  4WPV A;  3KCZ A;  5AKU A;  4L0B A;  4GV7 A;  4TJU A;  1OS1 A;  4UVU A;  4BUW A;  3BLJ A;  1YLH A;  4PJV A;  1J3B A;  4HL5 A;  4TK5 A;  1A26 A;  3DT4 A;  4UI6 A;  4BUS A;  3GEY A;  4ZZZ A;  4BUD A;  3C49 A;  4UW1 A;  3SMJ A;  4HHZ A;  1YGG A;  5FPF A;  4UVT A;  4DQY C;  4GNQ A;  4N4T A;  5C5R A;  4RCG A;  5ADQ A;  2PY7 X;  3UA9 A;  4L6Z A;  4BFP A;  3MHK A;  1XKV A;  4J22 A;  1PAX A;  4UVX A;  3P0P A;  4BU9 A;  4AVW A;  2ZCI A;  4K4F A;  4UI8 A;  5AL5 A;  5C5Q A;  5ADS A;  4N3R A;  4BUX A;  4L33 A;  4PY4 A;  4HKK A;  4BUF A;  4PNT A;  4L09 A;  2RKE A;  5FH2 A;  4UI3 A;  4TKF A;  1YTM A;  4L0I A;  3UH2 A;  5ADT A;  2GMV A;  4L70 A;  5FPG A;  3U9H A;  4YWB A;  2X5Y A;  4F1L A;  4L7L A;  5LYH A;  4PAX A;  4GV0 A;  4GNM A;  4L32 A;  4W5S A;  3DT7 A;  4GMM A;  4J3L A;  1AQ2 A;  4UVL A;  1K3C A;  5ADR A;  2FAF A;  3L3L A;  4UFY A;  4BUU A;  4BU7 A;  2RD6 A;  5LXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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