5GH0A

Crystal structure of the complex of bovine lactoperoxidase with mercaptoimidazole at 2.3 a resolution
Total Genus 184
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
184
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 angstrom resolution
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Lactoperoxidase
total genus 184
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2016-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 5gh0A00
4OTYA 1U67A 5F1AA 1DDXA 4RRWA 3PGHA 4M10A 3LN1A 1MYPC 4GN6A 5IKRA 3HS7A 3GC1A 5JW1A 2AYLA 4GM7A 5F19A 3PY4A 5B72A 4NT3A 2PT3A 3QMOA 2O86A 1DNUC 2R5LA 1HT8A 3ERHA 4HHSA 3HS6A 3N8WA 3UBAA 3V6QA 3QF1A 3GCJA 4Z0LA 4PH9A 3KK6A 3ZS1C 3TGYA 1DNWC 3N8XA 4OEKA 4O1ZA 3R4XA 5IKQA 3QL6A 4PNXA 3N8YB 4DL1C 4RS0A 3BXIA 5FIWC 2OYUP 1PGEA 5IKTA 3MDLA 4KSZA 1EBVA 3OLUA 4N7AA 1DIYA 4IG5A 3N8FA 1PXXA 3NTGA 3ZS0C 1PTHA 3NYHA 3KRQA 3RKEA 2EHAA 1IGXA 1D7WC 2OJVA 3FNLA 2QPKA 1CX2A 3FAQA 4RUTA 5HPWA 3I6NA 1Q4GA 2PUMA 1HT5A 4Y55A 3R55A 1EQHA 3RR3A 1CQEA 5GLSA 2EFBA 3NT1A 2GJMA 4MSFA 3QH0A 3ERIA 4E1GA 1CXPC 3OLTA 2NQXA 4FM5A 3KRKA 3OGWA 1IGZA 3MQEA 3NIUA 3Q7DA 4RRXA 6COXA 3SXVA 4C1MC 5IKVA 5JVZA 4LJJA 5KIRA 2QQTA 3F9PC 3HS5A 2Z5ZA 3N8YA 1EQGA 3N8WB 3N8VA 3NAKA 3R5QA 4NJBA 4KVKA 1FE2A 3N8ZA 2E9EA 3NTBA 4HHRA 4QYQA 5FDQA 1PRHA 4COXA 5COXA 4RRZA 5JVYA 1MHLC 2OYEP 4KVJA 5GH0A 3S4FA 3TZIA 3GCKA 3Q9KA 4QJQA 2IPSA 3GCLA 3R5OA 5FF1A 1D5LC 1D2VC 4OTJA 2IKCA 4KVLA 1CVUA 4M11A 2QRBA 3LN0A 4RRYA
chains in the Genus database with same CATH superfamily
4OTYA 1U67A 5F1AA 1DDXA 4RRWA 3PGHA 4M10A 3LN1A 1MYPC 4GN6A 5IKRA 3HS7A 3GC1A 5JW1A 2AYLA 4GM7A 5F19A 3PY4A 5B72A 4NT3A 2PT3A 3QMOA 2O86A 1DNUC 2R5LA 1HT8A 3ERHA 4HHSA 3HS6A 3N8WA 3UBAA 3V6QA 3QF1A 3GCJA 4Z0LA 4PH9A 3KK6A 3ZS1C 3TGYA 1DNWC 3N8XA 4OEKA 4O1ZA 3R4XA 5IKQA 3QL6A 4PNXA 3N8YB 4DL1C 4RS0A 3BXIA 5FIWC 2OYUP 1PGEA 5IKTA 3MDLA 4KSZA 1EBVA 3OLUA 4N7AA 1DIYA 4IG5A 3N8FA 1PXXA 3NTGA 3ZS0C 1PTHA 3NYHA 3KRQA 3RKEA 2EHAA 1IGXA 1D7WC 2OJVA 3FNLA 2QPKA 1CX2A 3FAQA 4RUTA 5HPWA 3I6NA 1Q4GA 2PUMA 1HT5A 4Y55A 3R55A 1EQHA 3RR3A 1CQEA 5GLSA 2EFBA 3NT1A 2GJMA 4MSFA 3QH0A 3ERIA 4E1GA 1CXPC 3OLTA 2NQXA 4FM5A 3KRKA 3OGWA 1IGZA 3MQEA 3NIUA 3Q7DA 4RRXA 6COXA 3SXVA 4C1MC 5IKVA 5JVZA 4LJJA 5KIRA 2QQTA 3F9PC 3HS5A 2Z5ZA 3N8YA 1EQGA 3N8WB 3N8VA 3NAKA 3R5QA 4NJBA 4KVKA 1FE2A 3N8ZA 2E9EA 3NTBA 4HHRA 4QYQA 5FDQA 1PRHA 4COXA 5COXA 4RRZA 5JVYA 1MHLC 2OYEP 4KVJA 5GH0A 3S4FA 3TZIA 3GCKA 3Q9KA 4QJQA 2IPSA 3GCLA 3R5OA 5FF1A 1D5LC 1D2VC 4OTJA 2IKCA 4KVLA 1CVUA 4M11A 2QRBA 3LN0A 4RRYA
chains in the Genus database with same CATH topology
4OTYA 1U67A 5F1AA 1DDXA 4RRWA 3PGHA 4M10A 3LN1A 1MYPC 4GN6A 5IKRA 3HS7A 3GC1A 5JW1A 2AYLA 4GM7A 5F19A 3PY4A 5B72A 4NT3A 2PT3A 3QMOA 2O86A 1DNUC 2R5LA 1HT8A 3ERHA 4HHSA 3HS6A 3N8WA 3UBAA 3V6QA 3QF1A 3GCJA 4Z0LA 4PH9A 3KK6A 3ZS1C 3TGYA 1DNWC 3N8XA 4OEKA 4O1ZA 3R4XA 5IKQA 3QL6A 4PNXA 3N8YB 4DL1C 4RS0A 3BXIA 5FIWC 2OYUP 1PGEA 5IKTA 3MDLA 4KSZA 1EBVA 3OLUA 4N7AA 1DIYA 4IG5A 3N8FA 1PXXA 3NTGA 3ZS0C 1PTHA 3NYHA 3KRQA 3RKEA 2EHAA 1IGXA 1D7WC 2OJVA 3FNLA 2QPKA 1CX2A 3FAQA 4RUTA 5HPWA 3I6NA 1Q4GA 2PUMA 1HT5A 4Y55A 3R55A 1EQHA 3RR3A 1CQEA 5GLSA 2EFBA 3NT1A 2GJMA 4MSFA 3QH0A 3ERIA 4E1GA 1CXPC 3OLTA 2NQXA 4FM5A 3KRKA 3OGWA 1IGZA 3MQEA 3NIUA 3Q7DA 4RRXA 6COXA 3SXVA 4C1MC 5IKVA 5JVZA 4LJJA 5KIRA 2QQTA 3F9PC 3HS5A 2Z5ZA 3N8YA 1EQGA 3N8WB 3N8VA 3NAKA 3R5QA 4NJBA 4KVKA 1FE2A 3N8ZA 2E9EA 3NTBA 4HHRA 4QYQA 5FDQA 1PRHA 4COXA 5COXA 4RRZA 5JVYA 1MHLC 2OYEP 4KVJA 5GH0A 3S4FA 3TZIA 3GCKA 3Q9KA 4QJQA 2IPSA 3GCLA 3R5OA 5FF1A 1D5LC 1D2VC 4OTJA 2IKCA 4KVLA 1CVUA 4M11A 2QRBA 3LN0A 4RRYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OTY A;  1U67 A;  5F1A A;  1DDX A;  4RRW A;  3PGH A;  4M10 A;  3LN1 A;  1MYP C;  4GN6 A;  5IKR A;  3HS7 A;  3GC1 A;  5JW1 A;  2AYL A;  4GM7 A;  5F19 A;  3PY4 A;  5B72 A;  4NT3 A;  2PT3 A;  3QMO A;  2O86 A;  1DNU C;  2R5L A;  1HT8 A;  3ERH A;  4HHS A;  3HS6 A;  3N8W A;  3UBA A;  3V6Q A;  3QF1 A;  3GCJ A;  4Z0L A;  4PH9 A;  3KK6 A;  3ZS1 C;  3TGY A;  1DNW C;  3N8X A;  4OEK A;  4O1Z A;  3R4X A;  5IKQ A;  3QL6 A;  4PNX A;  3N8Y B;  4DL1 C;  4RS0 A;  3BXI A;  5FIW C;  2OYU P;  1PGE A;  5IKT A;  3MDL A;  4KSZ A;  1EBV A;  3OLU A;  4N7A A;  1DIY A;  4IG5 A;  3N8F A;  1PXX A;  3NTG A;  3ZS0 C;  1PTH A;  3NYH A;  3KRQ A;  3RKE A;  2EHA A;  1IGX A;  1D7W C;  2OJV A;  3FNL A;  2QPK A;  1CX2 A;  3FAQ A;  4RUT A;  5HPW A;  3I6N A;  1Q4G A;  2PUM A;  1HT5 A;  4Y55 A;  3R55 A;  1EQH A;  3RR3 A;  1CQE A;  5GLS A;  2EFB A;  3NT1 A;  2GJM A;  4MSF A;  3QH0 A;  3ERI A;  4E1G A;  1CXP C;  3OLT A;  2NQX A;  4FM5 A;  3KRK A;  3OGW A;  1IGZ A;  3MQE A;  3NIU A;  3Q7D A;  4RRX A;  6COX A;  3SXV A;  4C1M C;  5IKV A;  5JVZ A;  4LJJ A;  5KIR A;  2QQT A;  3F9P C;  3HS5 A;  2Z5Z A;  3N8Y A;  1EQG A;  3N8W B;  3N8V A;  3NAK A;  3R5Q A;  4NJB A;  4KVK A;  1FE2 A;  3N8Z A;  2E9E A;  3NTB A;  4HHR A;  4QYQ A;  5FDQ A;  1PRH A;  4COX A;  5COX A;  4RRZ A;  5JVY A;  1MHL C;  2OYE P;  4KVJ A;  5GH0 A;  3S4F A;  3TZI A;  3GCK A;  3Q9K A;  4QJQ A;  2IPS A;  3GCL A;  3R5O A;  5FF1 A;  1D5L C;  1D2V C;  4OTJ A;  2IKC A;  4KVL A;  1CVU A;  4M11 A;  2QRB A;  3LN0 A;  4RRY A; 
#chains in the Genus database with same CATH topology
 4OTY A;  1U67 A;  5F1A A;  1DDX A;  4RRW A;  3PGH A;  4M10 A;  3LN1 A;  1MYP C;  4GN6 A;  5IKR A;  3HS7 A;  3GC1 A;  5JW1 A;  2AYL A;  4GM7 A;  5F19 A;  3PY4 A;  5B72 A;  4NT3 A;  2PT3 A;  3QMO A;  2O86 A;  1DNU C;  2R5L A;  1HT8 A;  3ERH A;  4HHS A;  3HS6 A;  3N8W A;  3UBA A;  3V6Q A;  3QF1 A;  3GCJ A;  4Z0L A;  4PH9 A;  3KK6 A;  3ZS1 C;  3TGY A;  1DNW C;  3N8X A;  4OEK A;  4O1Z A;  3R4X A;  5IKQ A;  3QL6 A;  4PNX A;  3N8Y B;  4DL1 C;  4RS0 A;  3BXI A;  5FIW C;  2OYU P;  1PGE A;  5IKT A;  3MDL A;  4KSZ A;  1EBV A;  3OLU A;  4N7A A;  1DIY A;  4IG5 A;  3N8F A;  1PXX A;  3NTG A;  3ZS0 C;  1PTH A;  3NYH A;  3KRQ A;  3RKE A;  2EHA A;  1IGX A;  1D7W C;  2OJV A;  3FNL A;  2QPK A;  1CX2 A;  3FAQ A;  4RUT A;  5HPW A;  3I6N A;  1Q4G A;  2PUM A;  1HT5 A;  4Y55 A;  3R55 A;  1EQH A;  3RR3 A;  1CQE A;  5GLS A;  2EFB A;  3NT1 A;  2GJM A;  4MSF A;  3QH0 A;  3ERI A;  4E1G A;  1CXP C;  3OLT A;  2NQX A;  4FM5 A;  3KRK A;  3OGW A;  1IGZ A;  3MQE A;  3NIU A;  3Q7D A;  4RRX A;  6COX A;  3SXV A;  4C1M C;  5IKV A;  5JVZ A;  4LJJ A;  5KIR A;  2QQT A;  3F9P C;  3HS5 A;  2Z5Z A;  3N8Y A;  1EQG A;  3N8W B;  3N8V A;  3NAK A;  3R5Q A;  4NJB A;  4KVK A;  1FE2 A;  3N8Z A;  2E9E A;  3NTB A;  4HHR A;  4QYQ A;  5FDQ A;  1PRH A;  4COX A;  5COX A;  4RRZ A;  5JVY A;  1MHL C;  2OYE P;  4KVJ A;  5GH0 A;  3S4F A;  3TZI A;  3GCK A;  3Q9K A;  4QJQ A;  2IPS A;  3GCL A;  3R5O A;  5FF1 A;  1D5L C;  1D2V C;  4OTJ A;  2IKC A;  4KVL A;  1CVU A;  4M11 A;  2QRB A;  3LN0 A;  4RRY A; 
#chains in the Genus database with same CATH homology
 4OTY A;  1U67 A;  5F1A A;  1DDX A;  4RRW A;  3PGH A;  4M10 A;  3LN1 A;  1MYP C;  4GN6 A;  5IKR A;  3HS7 A;  3GC1 A;  5JW1 A;  2AYL A;  4GM7 A;  5F19 A;  3PY4 A;  5B72 A;  4NT3 A;  2PT3 A;  3QMO A;  2O86 A;  1DNU C;  2R5L A;  1HT8 A;  3ERH A;  4HHS A;  3HS6 A;  3N8W A;  3UBA A;  3V6Q A;  3QF1 A;  3GCJ A;  4Z0L A;  4PH9 A;  3KK6 A;  3ZS1 C;  3TGY A;  1DNW C;  3N8X A;  4OEK A;  4O1Z A;  3R4X A;  5IKQ A;  3QL6 A;  4PNX A;  3N8Y B;  4DL1 C;  4RS0 A;  3BXI A;  5FIW C;  2OYU P;  1PGE A;  5IKT A;  3MDL A;  4KSZ A;  1EBV A;  3OLU A;  4N7A A;  1DIY A;  4IG5 A;  3N8F A;  1PXX A;  3NTG A;  3ZS0 C;  1PTH A;  3NYH A;  3KRQ A;  3RKE A;  2EHA A;  1IGX A;  1D7W C;  2OJV A;  3FNL A;  2QPK A;  1CX2 A;  3FAQ A;  4RUT A;  5HPW A;  3I6N A;  1Q4G A;  2PUM A;  1HT5 A;  4Y55 A;  3R55 A;  1EQH A;  3RR3 A;  1CQE A;  5GLS A;  2EFB A;  3NT1 A;  2GJM A;  4MSF A;  3QH0 A;  3ERI A;  4E1G A;  1CXP C;  3OLT A;  2NQX A;  4FM5 A;  3KRK A;  3OGW A;  1IGZ A;  3MQE A;  3NIU A;  3Q7D A;  4RRX A;  6COX A;  3SXV A;  4C1M C;  5IKV A;  5JVZ A;  4LJJ A;  5KIR A;  2QQT A;  3F9P C;  3HS5 A;  2Z5Z A;  3N8Y A;  1EQG A;  3N8W B;  3N8V A;  3NAK A;  3R5Q A;  4NJB A;  4KVK A;  1FE2 A;  3N8Z A;  2E9E A;  3NTB A;  4HHR A;  4QYQ A;  5FDQ A;  1PRH A;  4COX A;  5COX A;  4RRZ A;  5JVY A;  1MHL C;  2OYE P;  4KVJ A;  5GH0 A;  3S4F A;  3TZI A;  3GCK A;  3Q9K A;  4QJQ A;  2IPS A;  3GCL A;  3R5O A;  5FF1 A;  1D5L C;  1D2V C;  4OTJ A;  2IKC A;  4KVL A;  1CVU A;  4M11 A;  2QRB A;  3LN0 A;  4RRY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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