5GH0A

Crystal structure of the complex of bovine lactoperoxidase with mercaptoimidazole at 2.3 a resolution
Total Genus 184
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
184
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 angstrom resolution
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Lactoperoxidase
total genus 184
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2016-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 5gh0A00
4QJQA 2EFBA 2IKCA 2AYLA 2R5LA 1CXPC 1U67A 2E9EA 2OYUP 2QPKA 3N8YB 4M11A 3QL6A 3PGHA 1D7WC 4GN6A 3TGYA 4C1MC 4HHSA 5JVZA 3NT1A 1IGXA 4KVKA 3TZIA 4Y55A 2QQTA 3LN0A 5F1AA 5JW1A 3N8WB 4KSZA 1PTHA 4RRYA 2PUMA 3I6NA 4RUTA 3ERIA 4NT3A 3Q7DA 2PT3A 3KK6A 4NJBA 3R5QA 1D2VC 3HS6A 1PXXA 3V6QA 4RS0A 3NIUA 5IKQA 4RRZA 2GJMA 1PGEA 5COXA 3NAKA 1PRHA 3N8YA 1DNWC 5B72A 3MDLA 3QMOA 2IPSA 4PH9A 3HS7A 4DL1C 5HPWA 3S4FA 6COXA 3NTGA 3OLUA 4KVLA 3N8WA 2O86A 1Q4GA 5FDQA 3LN1A 3NTBA 4IG5A 5GLSA 5IKTA 3KRKA 4MSFA 3FNLA 1EBVA 1DIYA 3ZS0C 5IKRA 1CX2A 1DNUC 5IKVA 5KIRA 4QYQA 5F19A 4RRWA 2OYEP 4RRXA 3Q9KA 4E1GA 3ERHA 3R4XA 3UBAA 3QF1A 2QRBA 1IGZA 3BXIA 5FF1A 2EHAA 3N8XA 1FE2A 1D5LC 3FAQA 4FM5A 4KVJA 3GCLA 1MYPC 1EQHA 1HT5A 3RKEA 3MQEA 4M10A 1MHLC 3HS5A 3N8ZA 1EQGA 1CVUA 3OLTA 3RR3A 3R5OA 5GH0A 4N7AA 3N8FA 1DDXA 4O1ZA 2Z5ZA 3SXVA 3N8VA 4LJJA 3QH0A 5FIWC 3F9PC 1CQEA 1HT8A 3PY4A 4Z0LA 2NQXA 3GCJA 4OEKA 4PNXA 4HHRA 3OGWA 4COXA 2OJVA 4OTJA 3GC1A 4GM7A 5JVYA 3R55A 3KRQA 3NYHA 3ZS1C 3GCKA 4OTYA
chains in the Genus database with same CATH superfamily
4QJQA 2EFBA 2IKCA 2AYLA 2R5LA 1CXPC 1U67A 2E9EA 2OYUP 2QPKA 3N8YB 4M11A 3QL6A 3PGHA 1D7WC 4GN6A 3TGYA 4C1MC 4HHSA 5JVZA 3NT1A 1IGXA 4KVKA 3TZIA 4Y55A 2QQTA 3LN0A 5F1AA 5JW1A 3N8WB 4KSZA 1PTHA 4RRYA 2PUMA 3I6NA 4RUTA 3ERIA 4NT3A 3Q7DA 2PT3A 3KK6A 4NJBA 3R5QA 1D2VC 3HS6A 1PXXA 3V6QA 4RS0A 3NIUA 5IKQA 4RRZA 2GJMA 1PGEA 5COXA 3NAKA 1PRHA 3N8YA 1DNWC 5B72A 3MDLA 3QMOA 2IPSA 4PH9A 3HS7A 4DL1C 5HPWA 3S4FA 6COXA 3NTGA 3OLUA 4KVLA 3N8WA 2O86A 1Q4GA 5FDQA 3LN1A 3NTBA 4IG5A 5GLSA 5IKTA 3KRKA 4MSFA 3FNLA 1EBVA 1DIYA 3ZS0C 5IKRA 1CX2A 1DNUC 5IKVA 5KIRA 4QYQA 5F19A 4RRWA 2OYEP 4RRXA 3Q9KA 4E1GA 3ERHA 3R4XA 3UBAA 3QF1A 2QRBA 1IGZA 3BXIA 5FF1A 2EHAA 3N8XA 1FE2A 1D5LC 3FAQA 4FM5A 4KVJA 3GCLA 1MYPC 1EQHA 1HT5A 3RKEA 3MQEA 4M10A 1MHLC 3HS5A 3N8ZA 1EQGA 1CVUA 3OLTA 3RR3A 3R5OA 5GH0A 4N7AA 3N8FA 1DDXA 4O1ZA 2Z5ZA 3SXVA 3N8VA 4LJJA 3QH0A 5FIWC 3F9PC 1CQEA 1HT8A 3PY4A 4Z0LA 2NQXA 3GCJA 4OEKA 4PNXA 4HHRA 3OGWA 4COXA 2OJVA 4OTJA 3GC1A 4GM7A 5JVYA 3R55A 3KRQA 3NYHA 3ZS1C 3GCKA 4OTYA
chains in the Genus database with same CATH topology
4QJQA 2EFBA 2IKCA 2AYLA 2R5LA 1CXPC 1U67A 2E9EA 2OYUP 2QPKA 3N8YB 4M11A 3QL6A 3PGHA 1D7WC 4GN6A 3TGYA 4C1MC 4HHSA 5JVZA 3NT1A 1IGXA 4KVKA 3TZIA 4Y55A 2QQTA 3LN0A 5F1AA 5JW1A 3N8WB 4KSZA 1PTHA 4RRYA 2PUMA 3I6NA 4RUTA 3ERIA 4NT3A 3Q7DA 2PT3A 3KK6A 4NJBA 3R5QA 1D2VC 3HS6A 1PXXA 3V6QA 4RS0A 3NIUA 5IKQA 4RRZA 2GJMA 1PGEA 5COXA 3NAKA 1PRHA 3N8YA 1DNWC 5B72A 3MDLA 3QMOA 2IPSA 4PH9A 3HS7A 4DL1C 5HPWA 3S4FA 6COXA 3NTGA 3OLUA 4KVLA 3N8WA 2O86A 1Q4GA 5FDQA 3LN1A 3NTBA 4IG5A 5GLSA 5IKTA 3KRKA 4MSFA 3FNLA 1EBVA 1DIYA 3ZS0C 5IKRA 1CX2A 1DNUC 5IKVA 5KIRA 4QYQA 5F19A 4RRWA 2OYEP 4RRXA 3Q9KA 4E1GA 3ERHA 3R4XA 3UBAA 3QF1A 2QRBA 1IGZA 3BXIA 5FF1A 2EHAA 3N8XA 1FE2A 1D5LC 3FAQA 4FM5A 4KVJA 3GCLA 1MYPC 1EQHA 1HT5A 3RKEA 3MQEA 4M10A 1MHLC 3HS5A 3N8ZA 1EQGA 1CVUA 3OLTA 3RR3A 3R5OA 5GH0A 4N7AA 3N8FA 1DDXA 4O1ZA 2Z5ZA 3SXVA 3N8VA 4LJJA 3QH0A 5FIWC 3F9PC 1CQEA 1HT8A 3PY4A 4Z0LA 2NQXA 3GCJA 4OEKA 4PNXA 4HHRA 3OGWA 4COXA 2OJVA 4OTJA 3GC1A 4GM7A 5JVYA 3R55A 3KRQA 3NYHA 3ZS1C 3GCKA 4OTYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QJQ A;  2EFB A;  2IKC A;  2AYL A;  2R5L A;  1CXP C;  1U67 A;  2E9E A;  2OYU P;  2QPK A;  3N8Y B;  4M11 A;  3QL6 A;  3PGH A;  1D7W C;  4GN6 A;  3TGY A;  4C1M C;  4HHS A;  5JVZ A;  3NT1 A;  1IGX A;  4KVK A;  3TZI A;  4Y55 A;  2QQT A;  3LN0 A;  5F1A A;  5JW1 A;  3N8W B;  4KSZ A;  1PTH A;  4RRY A;  2PUM A;  3I6N A;  4RUT A;  3ERI A;  4NT3 A;  3Q7D A;  2PT3 A;  3KK6 A;  4NJB A;  3R5Q A;  1D2V C;  3HS6 A;  1PXX A;  3V6Q A;  4RS0 A;  3NIU A;  5IKQ A;  4RRZ A;  2GJM A;  1PGE A;  5COX A;  3NAK A;  1PRH A;  3N8Y A;  1DNW C;  5B72 A;  3MDL A;  3QMO A;  2IPS A;  4PH9 A;  3HS7 A;  4DL1 C;  5HPW A;  3S4F A;  6COX A;  3NTG A;  3OLU A;  4KVL A;  3N8W A;  2O86 A;  1Q4G A;  5FDQ A;  3LN1 A;  3NTB A;  4IG5 A;  5GLS A;  5IKT A;  3KRK A;  4MSF A;  3FNL A;  1EBV A;  1DIY A;  3ZS0 C;  5IKR A;  1CX2 A;  1DNU C;  5IKV A;  5KIR A;  4QYQ A;  5F19 A;  4RRW A;  2OYE P;  4RRX A;  3Q9K A;  4E1G A;  3ERH A;  3R4X A;  3UBA A;  3QF1 A;  2QRB A;  1IGZ A;  3BXI A;  5FF1 A;  2EHA A;  3N8X A;  1FE2 A;  1D5L C;  3FAQ A;  4FM5 A;  4KVJ A;  3GCL A;  1MYP C;  1EQH A;  1HT5 A;  3RKE A;  3MQE A;  4M10 A;  1MHL C;  3HS5 A;  3N8Z A;  1EQG A;  1CVU A;  3OLT A;  3RR3 A;  3R5O A;  5GH0 A;  4N7A A;  3N8F A;  1DDX A;  4O1Z A;  2Z5Z A;  3SXV A;  3N8V A;  4LJJ A;  3QH0 A;  5FIW C;  3F9P C;  1CQE A;  1HT8 A;  3PY4 A;  4Z0L A;  2NQX A;  3GCJ A;  4OEK A;  4PNX A;  4HHR A;  3OGW A;  4COX A;  2OJV A;  4OTJ A;  3GC1 A;  4GM7 A;  5JVY A;  3R55 A;  3KRQ A;  3NYH A;  3ZS1 C;  3GCK A;  4OTY A; 
#chains in the Genus database with same CATH topology
 4QJQ A;  2EFB A;  2IKC A;  2AYL A;  2R5L A;  1CXP C;  1U67 A;  2E9E A;  2OYU P;  2QPK A;  3N8Y B;  4M11 A;  3QL6 A;  3PGH A;  1D7W C;  4GN6 A;  3TGY A;  4C1M C;  4HHS A;  5JVZ A;  3NT1 A;  1IGX A;  4KVK A;  3TZI A;  4Y55 A;  2QQT A;  3LN0 A;  5F1A A;  5JW1 A;  3N8W B;  4KSZ A;  1PTH A;  4RRY A;  2PUM A;  3I6N A;  4RUT A;  3ERI A;  4NT3 A;  3Q7D A;  2PT3 A;  3KK6 A;  4NJB A;  3R5Q A;  1D2V C;  3HS6 A;  1PXX A;  3V6Q A;  4RS0 A;  3NIU A;  5IKQ A;  4RRZ A;  2GJM A;  1PGE A;  5COX A;  3NAK A;  1PRH A;  3N8Y A;  1DNW C;  5B72 A;  3MDL A;  3QMO A;  2IPS A;  4PH9 A;  3HS7 A;  4DL1 C;  5HPW A;  3S4F A;  6COX A;  3NTG A;  3OLU A;  4KVL A;  3N8W A;  2O86 A;  1Q4G A;  5FDQ A;  3LN1 A;  3NTB A;  4IG5 A;  5GLS A;  5IKT A;  3KRK A;  4MSF A;  3FNL A;  1EBV A;  1DIY A;  3ZS0 C;  5IKR A;  1CX2 A;  1DNU C;  5IKV A;  5KIR A;  4QYQ A;  5F19 A;  4RRW A;  2OYE P;  4RRX A;  3Q9K A;  4E1G A;  3ERH A;  3R4X A;  3UBA A;  3QF1 A;  2QRB A;  1IGZ A;  3BXI A;  5FF1 A;  2EHA A;  3N8X A;  1FE2 A;  1D5L C;  3FAQ A;  4FM5 A;  4KVJ A;  3GCL A;  1MYP C;  1EQH A;  1HT5 A;  3RKE A;  3MQE A;  4M10 A;  1MHL C;  3HS5 A;  3N8Z A;  1EQG A;  1CVU A;  3OLT A;  3RR3 A;  3R5O A;  5GH0 A;  4N7A A;  3N8F A;  1DDX A;  4O1Z A;  2Z5Z A;  3SXV A;  3N8V A;  4LJJ A;  3QH0 A;  5FIW C;  3F9P C;  1CQE A;  1HT8 A;  3PY4 A;  4Z0L A;  2NQX A;  3GCJ A;  4OEK A;  4PNX A;  4HHR A;  3OGW A;  4COX A;  2OJV A;  4OTJ A;  3GC1 A;  4GM7 A;  5JVY A;  3R55 A;  3KRQ A;  3NYH A;  3ZS1 C;  3GCK A;  4OTY A; 
#chains in the Genus database with same CATH homology
 4QJQ A;  2EFB A;  2IKC A;  2AYL A;  2R5L A;  1CXP C;  1U67 A;  2E9E A;  2OYU P;  2QPK A;  3N8Y B;  4M11 A;  3QL6 A;  3PGH A;  1D7W C;  4GN6 A;  3TGY A;  4C1M C;  4HHS A;  5JVZ A;  3NT1 A;  1IGX A;  4KVK A;  3TZI A;  4Y55 A;  2QQT A;  3LN0 A;  5F1A A;  5JW1 A;  3N8W B;  4KSZ A;  1PTH A;  4RRY A;  2PUM A;  3I6N A;  4RUT A;  3ERI A;  4NT3 A;  3Q7D A;  2PT3 A;  3KK6 A;  4NJB A;  3R5Q A;  1D2V C;  3HS6 A;  1PXX A;  3V6Q A;  4RS0 A;  3NIU A;  5IKQ A;  4RRZ A;  2GJM A;  1PGE A;  5COX A;  3NAK A;  1PRH A;  3N8Y A;  1DNW C;  5B72 A;  3MDL A;  3QMO A;  2IPS A;  4PH9 A;  3HS7 A;  4DL1 C;  5HPW A;  3S4F A;  6COX A;  3NTG A;  3OLU A;  4KVL A;  3N8W A;  2O86 A;  1Q4G A;  5FDQ A;  3LN1 A;  3NTB A;  4IG5 A;  5GLS A;  5IKT A;  3KRK A;  4MSF A;  3FNL A;  1EBV A;  1DIY A;  3ZS0 C;  5IKR A;  1CX2 A;  1DNU C;  5IKV A;  5KIR A;  4QYQ A;  5F19 A;  4RRW A;  2OYE P;  4RRX A;  3Q9K A;  4E1G A;  3ERH A;  3R4X A;  3UBA A;  3QF1 A;  2QRB A;  1IGZ A;  3BXI A;  5FF1 A;  2EHA A;  3N8X A;  1FE2 A;  1D5L C;  3FAQ A;  4FM5 A;  4KVJ A;  3GCL A;  1MYP C;  1EQH A;  1HT5 A;  3RKE A;  3MQE A;  4M10 A;  1MHL C;  3HS5 A;  3N8Z A;  1EQG A;  1CVU A;  3OLT A;  3RR3 A;  3R5O A;  5GH0 A;  4N7A A;  3N8F A;  1DDX A;  4O1Z A;  2Z5Z A;  3SXV A;  3N8V A;  4LJJ A;  3QH0 A;  5FIW C;  3F9P C;  1CQE A;  1HT8 A;  3PY4 A;  4Z0L A;  2NQX A;  3GCJ A;  4OEK A;  4PNX A;  4HHR A;  3OGW A;  4COX A;  2OJV A;  4OTJ A;  3GC1 A;  4GM7 A;  5JVY A;  3R55 A;  3KRQ A;  3NYH A;  3ZS1 C;  3GCK A;  4OTY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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