5GH0A

Crystal structure of the complex of bovine lactoperoxidase with mercaptoimidazole at 2.3 a resolution
Total Genus 184
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
184
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 angstrom resolution
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Lactoperoxidase
total genus 184
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2016-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 5gh0A00
3OLTA 3N8WB 1CVUA 4KVJA 1EQGA 2EHAA 3NTGA 1DDXA 3RKEA 2QPKA 4OTYA 2QQTA 2PUMA 2IKCA 3FNLA 1MHLC 3ZS1C 1PGEA 3N8VA 3LN1A 3NYHA 3MDLA 4E1GA 4HHRA 5KIRA 4LJJA 4M10A 1PXXA 5IKTA 4NT3A 1CQEA 3KRQA 1PRHA 4RRZA 4PNXA 4RUTA 3NAKA 5IKRA 5FDQA 5IKQA 3S4FA 4O1ZA 3Q9KA 4GN6A 1HT5A 3NIUA 3QH0A 3HS7A 4QJQA 3UBAA 3F9PC 2EFBA 3QMOA 3GCKA 3PGHA 5HPWA 3FAQA 4GM7A 4NJBA 3ERIA 3HS6A 1FE2A 5FF1A 5GLSA 4M11A 3N8XA 2E9EA 4FM5A 1EBVA 5JVYA 2OYUP 3Q7DA 4DL1C 1IGZA 3V6QA 5GH0A 4QYQA 4Y55A 2R5LA 3N8YA 3OLUA 3R55A 4RRWA 5B72A 5F19A 4PH9A 3N8ZA 5JVZA 1MYPC 1IGXA 4KSZA 3GC1A 5COXA 3TGYA 3I6NA 3ZS0C 3BXIA 5F1AA 3N8FA 2OYEP 3PY4A 1DNWC 3N8WA 3QL6A 3TZIA 3MQEA 3KRKA 2Z5ZA 3NTBA 3HS5A 3ERHA 3KK6A 3R5QA 3R4XA 3OGWA 2PT3A 4Z0LA 2QRBA 3R5OA 1D2VC 1EQHA 3GCLA 3RR3A 4HHSA 1DIYA 1U67A 3SXVA 4KVLA 4RS0A 2IPSA 4C1MC 4IG5A 3QF1A 1HT8A 1D5LC 3NT1A 3LN0A 4MSFA 5FIWC 2AYLA 1CX2A 3N8YB 2O86A 6COXA 4OEKA 4RRXA 4COXA 2GJMA 4OTJA 4RRYA 2NQXA 1D7WC 1DNUC 1Q4GA 2OJVA 1CXPC 1PTHA 4KVKA 3GCJA 5IKVA 4N7AA 5JW1A
chains in the Genus database with same CATH superfamily
3OLTA 3N8WB 1CVUA 4KVJA 1EQGA 2EHAA 3NTGA 1DDXA 3RKEA 2QPKA 4OTYA 2QQTA 2PUMA 2IKCA 3FNLA 1MHLC 3ZS1C 1PGEA 3N8VA 3LN1A 3NYHA 3MDLA 4E1GA 4HHRA 5KIRA 4LJJA 4M10A 1PXXA 5IKTA 4NT3A 1CQEA 3KRQA 1PRHA 4RRZA 4PNXA 4RUTA 3NAKA 5IKRA 5FDQA 5IKQA 3S4FA 4O1ZA 3Q9KA 4GN6A 1HT5A 3NIUA 3QH0A 3HS7A 4QJQA 3UBAA 3F9PC 2EFBA 3QMOA 3GCKA 3PGHA 5HPWA 3FAQA 4GM7A 4NJBA 3ERIA 3HS6A 1FE2A 5FF1A 5GLSA 4M11A 3N8XA 2E9EA 4FM5A 1EBVA 5JVYA 2OYUP 3Q7DA 4DL1C 1IGZA 3V6QA 5GH0A 4QYQA 4Y55A 2R5LA 3N8YA 3OLUA 3R55A 4RRWA 5B72A 5F19A 4PH9A 3N8ZA 5JVZA 1MYPC 1IGXA 4KSZA 3GC1A 5COXA 3TGYA 3I6NA 3ZS0C 3BXIA 5F1AA 3N8FA 2OYEP 3PY4A 1DNWC 3N8WA 3QL6A 3TZIA 3MQEA 3KRKA 2Z5ZA 3NTBA 3HS5A 3ERHA 3KK6A 3R5QA 3R4XA 3OGWA 2PT3A 4Z0LA 2QRBA 3R5OA 1D2VC 1EQHA 3GCLA 3RR3A 4HHSA 1DIYA 1U67A 3SXVA 4KVLA 4RS0A 2IPSA 4C1MC 4IG5A 3QF1A 1HT8A 1D5LC 3NT1A 3LN0A 4MSFA 5FIWC 2AYLA 1CX2A 3N8YB 2O86A 6COXA 4OEKA 4RRXA 4COXA 2GJMA 4OTJA 4RRYA 2NQXA 1D7WC 1DNUC 1Q4GA 2OJVA 1CXPC 1PTHA 4KVKA 3GCJA 5IKVA 4N7AA 5JW1A
chains in the Genus database with same CATH topology
3OLTA 3N8WB 1CVUA 4KVJA 1EQGA 2EHAA 3NTGA 1DDXA 3RKEA 2QPKA 4OTYA 2QQTA 2PUMA 2IKCA 3FNLA 1MHLC 3ZS1C 1PGEA 3N8VA 3LN1A 3NYHA 3MDLA 4E1GA 4HHRA 5KIRA 4LJJA 4M10A 1PXXA 5IKTA 4NT3A 1CQEA 3KRQA 1PRHA 4RRZA 4PNXA 4RUTA 3NAKA 5IKRA 5FDQA 5IKQA 3S4FA 4O1ZA 3Q9KA 4GN6A 1HT5A 3NIUA 3QH0A 3HS7A 4QJQA 3UBAA 3F9PC 2EFBA 3QMOA 3GCKA 3PGHA 5HPWA 3FAQA 4GM7A 4NJBA 3ERIA 3HS6A 1FE2A 5FF1A 5GLSA 4M11A 3N8XA 2E9EA 4FM5A 1EBVA 5JVYA 2OYUP 3Q7DA 4DL1C 1IGZA 3V6QA 5GH0A 4QYQA 4Y55A 2R5LA 3N8YA 3OLUA 3R55A 4RRWA 5B72A 5F19A 4PH9A 3N8ZA 5JVZA 1MYPC 1IGXA 4KSZA 3GC1A 5COXA 3TGYA 3I6NA 3ZS0C 3BXIA 5F1AA 3N8FA 2OYEP 3PY4A 1DNWC 3N8WA 3QL6A 3TZIA 3MQEA 3KRKA 2Z5ZA 3NTBA 3HS5A 3ERHA 3KK6A 3R5QA 3R4XA 3OGWA 2PT3A 4Z0LA 2QRBA 3R5OA 1D2VC 1EQHA 3GCLA 3RR3A 4HHSA 1DIYA 1U67A 3SXVA 4KVLA 4RS0A 2IPSA 4C1MC 4IG5A 3QF1A 1HT8A 1D5LC 3NT1A 3LN0A 4MSFA 5FIWC 2AYLA 1CX2A 3N8YB 2O86A 6COXA 4OEKA 4RRXA 4COXA 2GJMA 4OTJA 4RRYA 2NQXA 1D7WC 1DNUC 1Q4GA 2OJVA 1CXPC 1PTHA 4KVKA 3GCJA 5IKVA 4N7AA 5JW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OLT A;  3N8W B;  1CVU A;  4KVJ A;  1EQG A;  2EHA A;  3NTG A;  1DDX A;  3RKE A;  2QPK A;  4OTY A;  2QQT A;  2PUM A;  2IKC A;  3FNL A;  1MHL C;  3ZS1 C;  1PGE A;  3N8V A;  3LN1 A;  3NYH A;  3MDL A;  4E1G A;  4HHR A;  5KIR A;  4LJJ A;  4M10 A;  1PXX A;  5IKT A;  4NT3 A;  1CQE A;  3KRQ A;  1PRH A;  4RRZ A;  4PNX A;  4RUT A;  3NAK A;  5IKR A;  5FDQ A;  5IKQ A;  3S4F A;  4O1Z A;  3Q9K A;  4GN6 A;  1HT5 A;  3NIU A;  3QH0 A;  3HS7 A;  4QJQ A;  3UBA A;  3F9P C;  2EFB A;  3QMO A;  3GCK A;  3PGH A;  5HPW A;  3FAQ A;  4GM7 A;  4NJB A;  3ERI A;  3HS6 A;  1FE2 A;  5FF1 A;  5GLS A;  4M11 A;  3N8X A;  2E9E A;  4FM5 A;  1EBV A;  5JVY A;  2OYU P;  3Q7D A;  4DL1 C;  1IGZ A;  3V6Q A;  5GH0 A;  4QYQ A;  4Y55 A;  2R5L A;  3N8Y A;  3OLU A;  3R55 A;  4RRW A;  5B72 A;  5F19 A;  4PH9 A;  3N8Z A;  5JVZ A;  1MYP C;  1IGX A;  4KSZ A;  3GC1 A;  5COX A;  3TGY A;  3I6N A;  3ZS0 C;  3BXI A;  5F1A A;  3N8F A;  2OYE P;  3PY4 A;  1DNW C;  3N8W A;  3QL6 A;  3TZI A;  3MQE A;  3KRK A;  2Z5Z A;  3NTB A;  3HS5 A;  3ERH A;  3KK6 A;  3R5Q A;  3R4X A;  3OGW A;  2PT3 A;  4Z0L A;  2QRB A;  3R5O A;  1D2V C;  1EQH A;  3GCL A;  3RR3 A;  4HHS A;  1DIY A;  1U67 A;  3SXV A;  4KVL A;  4RS0 A;  2IPS A;  4C1M C;  4IG5 A;  3QF1 A;  1HT8 A;  1D5L C;  3NT1 A;  3LN0 A;  4MSF A;  5FIW C;  2AYL A;  1CX2 A;  3N8Y B;  2O86 A;  6COX A;  4OEK A;  4RRX A;  4COX A;  2GJM A;  4OTJ A;  4RRY A;  2NQX A;  1D7W C;  1DNU C;  1Q4G A;  2OJV A;  1CXP C;  1PTH A;  4KVK A;  3GCJ A;  5IKV A;  4N7A A;  5JW1 A; 
#chains in the Genus database with same CATH topology
 3OLT A;  3N8W B;  1CVU A;  4KVJ A;  1EQG A;  2EHA A;  3NTG A;  1DDX A;  3RKE A;  2QPK A;  4OTY A;  2QQT A;  2PUM A;  2IKC A;  3FNL A;  1MHL C;  3ZS1 C;  1PGE A;  3N8V A;  3LN1 A;  3NYH A;  3MDL A;  4E1G A;  4HHR A;  5KIR A;  4LJJ A;  4M10 A;  1PXX A;  5IKT A;  4NT3 A;  1CQE A;  3KRQ A;  1PRH A;  4RRZ A;  4PNX A;  4RUT A;  3NAK A;  5IKR A;  5FDQ A;  5IKQ A;  3S4F A;  4O1Z A;  3Q9K A;  4GN6 A;  1HT5 A;  3NIU A;  3QH0 A;  3HS7 A;  4QJQ A;  3UBA A;  3F9P C;  2EFB A;  3QMO A;  3GCK A;  3PGH A;  5HPW A;  3FAQ A;  4GM7 A;  4NJB A;  3ERI A;  3HS6 A;  1FE2 A;  5FF1 A;  5GLS A;  4M11 A;  3N8X A;  2E9E A;  4FM5 A;  1EBV A;  5JVY A;  2OYU P;  3Q7D A;  4DL1 C;  1IGZ A;  3V6Q A;  5GH0 A;  4QYQ A;  4Y55 A;  2R5L A;  3N8Y A;  3OLU A;  3R55 A;  4RRW A;  5B72 A;  5F19 A;  4PH9 A;  3N8Z A;  5JVZ A;  1MYP C;  1IGX A;  4KSZ A;  3GC1 A;  5COX A;  3TGY A;  3I6N A;  3ZS0 C;  3BXI A;  5F1A A;  3N8F A;  2OYE P;  3PY4 A;  1DNW C;  3N8W A;  3QL6 A;  3TZI A;  3MQE A;  3KRK A;  2Z5Z A;  3NTB A;  3HS5 A;  3ERH A;  3KK6 A;  3R5Q A;  3R4X A;  3OGW A;  2PT3 A;  4Z0L A;  2QRB A;  3R5O A;  1D2V C;  1EQH A;  3GCL A;  3RR3 A;  4HHS A;  1DIY A;  1U67 A;  3SXV A;  4KVL A;  4RS0 A;  2IPS A;  4C1M C;  4IG5 A;  3QF1 A;  1HT8 A;  1D5L C;  3NT1 A;  3LN0 A;  4MSF A;  5FIW C;  2AYL A;  1CX2 A;  3N8Y B;  2O86 A;  6COX A;  4OEK A;  4RRX A;  4COX A;  2GJM A;  4OTJ A;  4RRY A;  2NQX A;  1D7W C;  1DNU C;  1Q4G A;  2OJV A;  1CXP C;  1PTH A;  4KVK A;  3GCJ A;  5IKV A;  4N7A A;  5JW1 A; 
#chains in the Genus database with same CATH homology
 3OLT A;  3N8W B;  1CVU A;  4KVJ A;  1EQG A;  2EHA A;  3NTG A;  1DDX A;  3RKE A;  2QPK A;  4OTY A;  2QQT A;  2PUM A;  2IKC A;  3FNL A;  1MHL C;  3ZS1 C;  1PGE A;  3N8V A;  3LN1 A;  3NYH A;  3MDL A;  4E1G A;  4HHR A;  5KIR A;  4LJJ A;  4M10 A;  1PXX A;  5IKT A;  4NT3 A;  1CQE A;  3KRQ A;  1PRH A;  4RRZ A;  4PNX A;  4RUT A;  3NAK A;  5IKR A;  5FDQ A;  5IKQ A;  3S4F A;  4O1Z A;  3Q9K A;  4GN6 A;  1HT5 A;  3NIU A;  3QH0 A;  3HS7 A;  4QJQ A;  3UBA A;  3F9P C;  2EFB A;  3QMO A;  3GCK A;  3PGH A;  5HPW A;  3FAQ A;  4GM7 A;  4NJB A;  3ERI A;  3HS6 A;  1FE2 A;  5FF1 A;  5GLS A;  4M11 A;  3N8X A;  2E9E A;  4FM5 A;  1EBV A;  5JVY A;  2OYU P;  3Q7D A;  4DL1 C;  1IGZ A;  3V6Q A;  5GH0 A;  4QYQ A;  4Y55 A;  2R5L A;  3N8Y A;  3OLU A;  3R55 A;  4RRW A;  5B72 A;  5F19 A;  4PH9 A;  3N8Z A;  5JVZ A;  1MYP C;  1IGX A;  4KSZ A;  3GC1 A;  5COX A;  3TGY A;  3I6N A;  3ZS0 C;  3BXI A;  5F1A A;  3N8F A;  2OYE P;  3PY4 A;  1DNW C;  3N8W A;  3QL6 A;  3TZI A;  3MQE A;  3KRK A;  2Z5Z A;  3NTB A;  3HS5 A;  3ERH A;  3KK6 A;  3R5Q A;  3R4X A;  3OGW A;  2PT3 A;  4Z0L A;  2QRB A;  3R5O A;  1D2V C;  1EQH A;  3GCL A;  3RR3 A;  4HHS A;  1DIY A;  1U67 A;  3SXV A;  4KVL A;  4RS0 A;  2IPS A;  4C1M C;  4IG5 A;  3QF1 A;  1HT8 A;  1D5L C;  3NT1 A;  3LN0 A;  4MSF A;  5FIW C;  2AYL A;  1CX2 A;  3N8Y B;  2O86 A;  6COX A;  4OEK A;  4RRX A;  4COX A;  2GJM A;  4OTJ A;  4RRY A;  2NQX A;  1D7W C;  1DNU C;  1Q4G A;  2OJV A;  1CXP C;  1PTH A;  4KVK A;  3GCJ A;  5IKV A;  4N7A A;  5JW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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