1ISQA

Pyrococcus furiosus pcna complexed with rfcl pip-box peptide
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
246
structure length
240
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEPELPFTAKVVVLGEVLKDAVKDASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
pubmed doi rcsb
molecule tags Dna binding protein
source organism Pyrococcus furiosus
molecule keywords Proliferating Cell Nuclear Antigen
total genus 59
structure length 240
sequence length 246
ec nomenclature
pdb deposition date 2001-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1isqA00
3V60B 3WGWA 2NTIB 2ZVLA 3G65C 1PLRA 1IZ4A 2ZVWA 2HIKB 4RJFA 2HIIB 3TBLA 3A1JA 5B7OA 1W60A 3HSLX 5E0TA 4TR6A 3FDSD 2IX2B 3IFVA 5IXAA 3GGRC 3GPNA 1ISQA 3V61B 5JNED 5H0TA 5A6DA 2HIKA 1T6LA 1YYPA 5DA7A 1U7BA 1RWZA 3AIXB 3P83A 2IX2A 5HACA 4L60A 3P87A 1CZDA 4HK1A 2IZOB 3G65A 1U76A 3AIZC 2IO4A 4CS5A 1DMLA 3A1JC 3A2FB 1UL1A 3AIXA 5AUJA 1GE8A 3HI8A 1IZ5A 3G65B 1SXJF 1UD9A 2IO4B 1AXCA 2NTIC 3V62B 3GGRA 3I2MX 3U61F 5E0UA 5DAIA 2HIKC 4YHRA 2OD8A 4L6PA 2HIIC 2ZVMA 5E0VA 1RXZA 1RXMA 3GGRB 2ZVVA 2IX2C 3K4XA 3LX2A 3P91A 2Z0LA 3U5ZF 4ZTDA 3U60F 1B77A 3FDSC 3GPMA 3AIZA 1VYJA 5IY4A 5CFKA 4D2GA 3F1WA 2IZOC 1PLQA 2AVTA 3LX1A 5IWDA 1B8HA 2AWAA 2NTIA 2ZVKA 3A1JB 2IJXA 3VKXA 1VYMA 2HIIA
chains in the Genus database with same CATH superfamily
3V60B 3WGWA 2NTIB 2ZVLA 3G65C 1PLRA 1IZ4A 2ZVWA 2HIKB 4RJFA 2HIIB 3TBLA 3A1JA 5B7OA 1W60A 3HSLX 5E0TA 4TR6A 3FDSD 2IX2B 3IFVA 5IXAA 3GGRC 3GPNA 1ISQA 3V61B 5JNED 5H0TA 5A6DA 2HIKA 1T6LA 1YYPA 5DA7A 1U7BA 1RWZA 3AIXB 3P83A 2IX2A 5HACA 4L60A 3P87A 1CZDA 4HK1A 2IZOB 3G65A 1U76A 3AIZC 2IO4A 4CS5A 1DMLA 3A1JC 3A2FB 1UL1A 3AIXA 5AUJA 1GE8A 3HI8A 1IZ5A 3G65B 1SXJF 1UD9A 2IO4B 1AXCA 2NTIC 3V62B 3GGRA 3I2MX 3U61F 5E0UA 5DAIA 2HIKC 4YHRA 2OD8A 4L6PA 2HIIC 2ZVMA 5E0VA 1RXZA 1RXMA 3GGRB 2ZVVA 2IX2C 3K4XA 3LX2A 3P91A 2Z0LA 3U5ZF 4ZTDA 3U60F 1B77A 3FDSC 3GPMA 3AIZA 1VYJA 5IY4A 5CFKA 4D2GA 3F1WA 2IZOC 1PLQA 2AVTA 3LX1A 5IWDA 1B8HA 2AWAA 2NTIA 2ZVKA 3A1JB 2IJXA 3VKXA 1VYMA 2HIIA
chains in the Genus database with same CATH topology
3V60B 3WGWA 2NTIB 2ZVLA 3G65C 1PLRA 1IZ4A 2ZVWA 2HIKB 4RJFA 2HIIB 3TBLA 3A1JA 5B7OA 1W60A 3HSLX 5E0TA 4TR6A 3FDSD 2IX2B 3IFVA 5IXAA 3GGRC 3GPNA 1ISQA 3V61B 5JNED 5H0TA 5A6DA 2HIKA 1T6LA 1YYPA 5DA7A 1U7BA 1RWZA 3AIXB 3P83A 2IX2A 5HACA 4L60A 3P87A 1CZDA 4HK1A 2IZOB 3G65A 1U76A 3AIZC 2IO4A 4CS5A 1DMLA 3A1JC 3A2FB 1UL1A 3AIXA 5AUJA 1GE8A 3HI8A 1IZ5A 3G65B 1SXJF 1UD9A 2IO4B 1AXCA 2NTIC 3V62B 3GGRA 3I2MX 3U61F 5E0UA 5DAIA 2HIKC 4YHRA 2OD8A 4L6PA 2HIIC 2ZVMA 5E0VA 1RXZA 1RXMA 3GGRB 2ZVVA 2IX2C 3K4XA 3LX2A 3P91A 2Z0LA 3U5ZF 4ZTDA 3U60F 1B77A 3FDSC 3GPMA 3AIZA 1VYJA 5IY4A 5CFKA 4D2GA 3F1WA 2IZOC 1PLQA 2AVTA 3LX1A 5IWDA 1B8HA 2AWAA 2NTIA 2ZVKA 3A1JB 2IJXA 3VKXA 1VYMA 2HIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V60 B;  3WGW A;  2NTI B;  2ZVL A;  3G65 C;  1PLR A;  1IZ4 A;  2ZVW A;  2HIK B;  4RJF A;  2HII B;  3TBL A;  3A1J A;  5B7O A;  1W60 A;  3HSL X;  5E0T A;  4TR6 A;  3FDS D;  2IX2 B;  3IFV A;  5IXA A;  3GGR C;  3GPN A;  1ISQ A;  3V61 B;  5JNE D;  5H0T A;  5A6D A;  2HIK A;  1T6L A;  1YYP A;  5DA7 A;  1U7B A;  1RWZ A;  3AIX B;  3P83 A;  2IX2 A;  5HAC A;  4L60 A;  3P87 A;  1CZD A;  4HK1 A;  2IZO B;  3G65 A;  1U76 A;  3AIZ C;  2IO4 A;  4CS5 A;  1DML A;  3A1J C;  3A2F B;  1UL1 A;  3AIX A;  5AUJ A;  1GE8 A;  3HI8 A;  1IZ5 A;  3G65 B;  1SXJ F;  1UD9 A;  2IO4 B;  1AXC A;  2NTI C;  3V62 B;  3GGR A;  3I2M X;  3U61 F;  5E0U A;  5DAI A;  2HIK C;  4YHR A;  2OD8 A;  4L6P A;  2HII C;  2ZVM A;  5E0V A;  1RXZ A;  1RXM A;  3GGR B;  2ZVV A;  2IX2 C;  3K4X A;  3LX2 A;  3P91 A;  2Z0L A;  3U5Z F;  4ZTD A;  3U60 F;  1B77 A;  3FDS C;  3GPM A;  3AIZ A;  1VYJ A;  5IY4 A;  5CFK A;  4D2G A;  3F1W A;  2IZO C;  1PLQ A;  2AVT A;  3LX1 A;  5IWD A;  1B8H A;  2AWA A;  2NTI A;  2ZVK A;  3A1J B;  2IJX A;  3VKX A;  1VYM A;  2HII A; 
#chains in the Genus database with same CATH topology
 3V60 B;  3WGW A;  2NTI B;  2ZVL A;  3G65 C;  1PLR A;  1IZ4 A;  2ZVW A;  2HIK B;  4RJF A;  2HII B;  3TBL A;  3A1J A;  5B7O A;  1W60 A;  3HSL X;  5E0T A;  4TR6 A;  3FDS D;  2IX2 B;  3IFV A;  5IXA A;  3GGR C;  3GPN A;  1ISQ A;  3V61 B;  5JNE D;  5H0T A;  5A6D A;  2HIK A;  1T6L A;  1YYP A;  5DA7 A;  1U7B A;  1RWZ A;  3AIX B;  3P83 A;  2IX2 A;  5HAC A;  4L60 A;  3P87 A;  1CZD A;  4HK1 A;  2IZO B;  3G65 A;  1U76 A;  3AIZ C;  2IO4 A;  4CS5 A;  1DML A;  3A1J C;  3A2F B;  1UL1 A;  3AIX A;  5AUJ A;  1GE8 A;  3HI8 A;  1IZ5 A;  3G65 B;  1SXJ F;  1UD9 A;  2IO4 B;  1AXC A;  2NTI C;  3V62 B;  3GGR A;  3I2M X;  3U61 F;  5E0U A;  5DAI A;  2HIK C;  4YHR A;  2OD8 A;  4L6P A;  2HII C;  2ZVM A;  5E0V A;  1RXZ A;  1RXM A;  3GGR B;  2ZVV A;  2IX2 C;  3K4X A;  3LX2 A;  3P91 A;  2Z0L A;  3U5Z F;  4ZTD A;  3U60 F;  1B77 A;  3FDS C;  3GPM A;  3AIZ A;  1VYJ A;  5IY4 A;  5CFK A;  4D2G A;  3F1W A;  2IZO C;  1PLQ A;  2AVT A;  3LX1 A;  5IWD A;  1B8H A;  2AWA A;  2NTI A;  2ZVK A;  3A1J B;  2IJX A;  3VKX A;  1VYM A;  2HII A; 
#chains in the Genus database with same CATH homology
 3V60 B;  3WGW A;  2NTI B;  2ZVL A;  3G65 C;  1PLR A;  1IZ4 A;  2ZVW A;  2HIK B;  4RJF A;  2HII B;  3TBL A;  3A1J A;  5B7O A;  1W60 A;  3HSL X;  5E0T A;  4TR6 A;  3FDS D;  2IX2 B;  3IFV A;  5IXA A;  3GGR C;  3GPN A;  1ISQ A;  3V61 B;  5JNE D;  5H0T A;  5A6D A;  2HIK A;  1T6L A;  1YYP A;  5DA7 A;  1U7B A;  1RWZ A;  3AIX B;  3P83 A;  2IX2 A;  5HAC A;  4L60 A;  3P87 A;  1CZD A;  4HK1 A;  2IZO B;  3G65 A;  1U76 A;  3AIZ C;  2IO4 A;  4CS5 A;  1DML A;  3A1J C;  3A2F B;  1UL1 A;  3AIX A;  5AUJ A;  1GE8 A;  3HI8 A;  1IZ5 A;  3G65 B;  1SXJ F;  1UD9 A;  2IO4 B;  1AXC A;  2NTI C;  3V62 B;  3GGR A;  3I2M X;  3U61 F;  5E0U A;  5DAI A;  2HIK C;  4YHR A;  2OD8 A;  4L6P A;  2HII C;  2ZVM A;  5E0V A;  1RXZ A;  1RXM A;  3GGR B;  2ZVV A;  2IX2 C;  3K4X A;  3LX2 A;  3P91 A;  2Z0L A;  3U5Z F;  4ZTD A;  3U60 F;  1B77 A;  3FDS C;  3GPM A;  3AIZ A;  1VYJ A;  5IY4 A;  5CFK A;  4D2G A;  3F1W A;  2IZO C;  1PLQ A;  2AVT A;  3LX1 A;  5IWD A;  1B8H A;  2AWA A;  2NTI A;  2ZVK A;  3A1J B;  2IJX A;  3VKX A;  1VYM A;  2HII A; 
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similar chains in the Genus database (?% sequence similarity)
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