2HIIC

Heterotrimeric pcna sliding clamp
Total Genus 61
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
243
structure length
243
Chain Sequence
MKVVYDDVRVLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYDVNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNREFNVRNLEVSEQEIPEINLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGESEVEVEFSKDTGGLQDLEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFFNMEGGGKVTYLLAPK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
pubmed doi rcsb
molecule keywords PCNA1 (SSO0397)
molecule tags Replication
source organism Sulfolobus solfataricus
total genus 61
structure length 243
sequence length 243
chains with identical sequence Z
ec nomenclature
pdb deposition date 2006-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
C PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2hiiC00
2OD8A 3K4XA 1RWZA 5HACA 3GGRA 4HK1A 5IWDA 3LX1A 2IO4A 2Z0LA 5H0TA 5DA7A 3A1JB 5AUJA 3GGRC 3A1JA 3LX2A 2IX2B 1T6LA 1ISQA 2ZVLA 3WGWA 2ZVWA 2HIIC 3V60B 3G65B 3A2FB 3GGRB 4D2GA 1VYMA 1B77A 3G65A 2IO4B 3V61B 5A6DA 1GE8A 1IZ5A 1RXMA 3I2MX 3G65C 3P87A 2HIIB 3HI8A 4L60A 1UD9A 5DAIA 2ZVKA 2HIIA 1VYJA 1U7BA 2ZVVA 3P91A 1AXCA 1DMLA 3U5ZF 3U60F 5IXAA 5E0TA 2NTIA 5E0UA 4CS5A 4YHRA 3AIXA 2HIKA 1CZDA 2NTIC 5CFKA 4L6PA 3U61F 1W60A 1PLRA 4RJFA 1SXJF 3V62B 2HIKC 1RXZA 1YYPA 2AWAA 5E0VA 3FDSD 3HSLX 2NTIB 1B8HA 4ZTDA 3AIZA 3AIXB 2HIKB 3VKXA 5B7OA 3GPMA 2IZOC 3P83A 2AVTA 1U76A 3AIZC 1UL1A 3F1WA 3IFVA 5JNED 1PLQA 2IJXA 2IX2A 3FDSC 2ZVMA 3GPNA 3TBLA 3A1JC 5IY4A 2IZOB 4TR6A 2IX2C 1IZ4A
chains in the Genus database with same CATH superfamily
2OD8A 3K4XA 1RWZA 5HACA 3GGRA 4HK1A 5IWDA 3LX1A 2IO4A 2Z0LA 5H0TA 5DA7A 3A1JB 5AUJA 3GGRC 3A1JA 3LX2A 2IX2B 1T6LA 1ISQA 2ZVLA 3WGWA 2ZVWA 2HIIC 3V60B 3G65B 3A2FB 3GGRB 4D2GA 1VYMA 1B77A 3G65A 2IO4B 3V61B 5A6DA 1GE8A 1IZ5A 1RXMA 3I2MX 3G65C 3P87A 2HIIB 3HI8A 4L60A 1UD9A 5DAIA 2ZVKA 2HIIA 1VYJA 1U7BA 2ZVVA 3P91A 1AXCA 1DMLA 3U5ZF 3U60F 5IXAA 5E0TA 2NTIA 5E0UA 4CS5A 4YHRA 3AIXA 2HIKA 1CZDA 2NTIC 5CFKA 4L6PA 3U61F 1W60A 1PLRA 4RJFA 1SXJF 3V62B 2HIKC 1RXZA 1YYPA 2AWAA 5E0VA 3FDSD 3HSLX 2NTIB 1B8HA 4ZTDA 3AIZA 3AIXB 2HIKB 3VKXA 5B7OA 3GPMA 2IZOC 3P83A 2AVTA 1U76A 3AIZC 1UL1A 3F1WA 3IFVA 5JNED 1PLQA 2IJXA 2IX2A 3FDSC 2ZVMA 3GPNA 3TBLA 3A1JC 5IY4A 2IZOB 4TR6A 2IX2C 1IZ4A
chains in the Genus database with same CATH topology
2OD8A 3K4XA 1RWZA 5HACA 3GGRA 4HK1A 5IWDA 3LX1A 2IO4A 2Z0LA 5H0TA 5DA7A 3A1JB 5AUJA 3GGRC 3A1JA 3LX2A 2IX2B 1T6LA 1ISQA 2ZVLA 3WGWA 2ZVWA 2HIIC 3V60B 3G65B 3A2FB 3GGRB 4D2GA 1VYMA 1B77A 3G65A 2IO4B 3V61B 5A6DA 1GE8A 1IZ5A 1RXMA 3I2MX 3G65C 3P87A 2HIIB 3HI8A 4L60A 1UD9A 5DAIA 2ZVKA 2HIIA 1VYJA 1U7BA 2ZVVA 3P91A 1AXCA 1DMLA 3U5ZF 3U60F 5IXAA 5E0TA 2NTIA 5E0UA 4CS5A 4YHRA 3AIXA 2HIKA 1CZDA 2NTIC 5CFKA 4L6PA 3U61F 1W60A 1PLRA 4RJFA 1SXJF 3V62B 2HIKC 1RXZA 1YYPA 2AWAA 5E0VA 3FDSD 3HSLX 2NTIB 1B8HA 4ZTDA 3AIZA 3AIXB 2HIKB 3VKXA 5B7OA 3GPMA 2IZOC 3P83A 2AVTA 1U76A 3AIZC 1UL1A 3F1WA 3IFVA 5JNED 1PLQA 2IJXA 2IX2A 3FDSC 2ZVMA 3GPNA 3TBLA 3A1JC 5IY4A 2IZOB 4TR6A 2IX2C 1IZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OD8 A;  3K4X A;  1RWZ A;  5HAC A;  3GGR A;  4HK1 A;  5IWD A;  3LX1 A;  2IO4 A;  2Z0L A;  5H0T A;  5DA7 A;  3A1J B;  5AUJ A;  3GGR C;  3A1J A;  3LX2 A;  2IX2 B;  1T6L A;  1ISQ A;  2ZVL A;  3WGW A;  2ZVW A;  2HII C;  3V60 B;  3G65 B;  3A2F B;  3GGR B;  4D2G A;  1VYM A;  1B77 A;  3G65 A;  2IO4 B;  3V61 B;  5A6D A;  1GE8 A;  1IZ5 A;  1RXM A;  3I2M X;  3G65 C;  3P87 A;  2HII B;  3HI8 A;  4L60 A;  1UD9 A;  5DAI A;  2ZVK A;  2HII A;  1VYJ A;  1U7B A;  2ZVV A;  3P91 A;  1AXC A;  1DML A;  3U5Z F;  3U60 F;  5IXA A;  5E0T A;  2NTI A;  5E0U A;  4CS5 A;  4YHR A;  3AIX A;  2HIK A;  1CZD A;  2NTI C;  5CFK A;  4L6P A;  3U61 F;  1W60 A;  1PLR A;  4RJF A;  1SXJ F;  3V62 B;  2HIK C;  1RXZ A;  1YYP A;  2AWA A;  5E0V A;  3FDS D;  3HSL X;  2NTI B;  1B8H A;  4ZTD A;  3AIZ A;  3AIX B;  2HIK B;  3VKX A;  5B7O A;  3GPM A;  2IZO C;  3P83 A;  2AVT A;  1U76 A;  3AIZ C;  1UL1 A;  3F1W A;  3IFV A;  5JNE D;  1PLQ A;  2IJX A;  2IX2 A;  3FDS C;  2ZVM A;  3GPN A;  3TBL A;  3A1J C;  5IY4 A;  2IZO B;  4TR6 A;  2IX2 C;  1IZ4 A; 
#chains in the Genus database with same CATH topology
 2OD8 A;  3K4X A;  1RWZ A;  5HAC A;  3GGR A;  4HK1 A;  5IWD A;  3LX1 A;  2IO4 A;  2Z0L A;  5H0T A;  5DA7 A;  3A1J B;  5AUJ A;  3GGR C;  3A1J A;  3LX2 A;  2IX2 B;  1T6L A;  1ISQ A;  2ZVL A;  3WGW A;  2ZVW A;  2HII C;  3V60 B;  3G65 B;  3A2F B;  3GGR B;  4D2G A;  1VYM A;  1B77 A;  3G65 A;  2IO4 B;  3V61 B;  5A6D A;  1GE8 A;  1IZ5 A;  1RXM A;  3I2M X;  3G65 C;  3P87 A;  2HII B;  3HI8 A;  4L60 A;  1UD9 A;  5DAI A;  2ZVK A;  2HII A;  1VYJ A;  1U7B A;  2ZVV A;  3P91 A;  1AXC A;  1DML A;  3U5Z F;  3U60 F;  5IXA A;  5E0T A;  2NTI A;  5E0U A;  4CS5 A;  4YHR A;  3AIX A;  2HIK A;  1CZD A;  2NTI C;  5CFK A;  4L6P A;  3U61 F;  1W60 A;  1PLR A;  4RJF A;  1SXJ F;  3V62 B;  2HIK C;  1RXZ A;  1YYP A;  2AWA A;  5E0V A;  3FDS D;  3HSL X;  2NTI B;  1B8H A;  4ZTD A;  3AIZ A;  3AIX B;  2HIK B;  3VKX A;  5B7O A;  3GPM A;  2IZO C;  3P83 A;  2AVT A;  1U76 A;  3AIZ C;  1UL1 A;  3F1W A;  3IFV A;  5JNE D;  1PLQ A;  2IJX A;  2IX2 A;  3FDS C;  2ZVM A;  3GPN A;  3TBL A;  3A1J C;  5IY4 A;  2IZO B;  4TR6 A;  2IX2 C;  1IZ4 A; 
#chains in the Genus database with same CATH homology
 2OD8 A;  3K4X A;  1RWZ A;  5HAC A;  3GGR A;  4HK1 A;  5IWD A;  3LX1 A;  2IO4 A;  2Z0L A;  5H0T A;  5DA7 A;  3A1J B;  5AUJ A;  3GGR C;  3A1J A;  3LX2 A;  2IX2 B;  1T6L A;  1ISQ A;  2ZVL A;  3WGW A;  2ZVW A;  2HII C;  3V60 B;  3G65 B;  3A2F B;  3GGR B;  4D2G A;  1VYM A;  1B77 A;  3G65 A;  2IO4 B;  3V61 B;  5A6D A;  1GE8 A;  1IZ5 A;  1RXM A;  3I2M X;  3G65 C;  3P87 A;  2HII B;  3HI8 A;  4L60 A;  1UD9 A;  5DAI A;  2ZVK A;  2HII A;  1VYJ A;  1U7B A;  2ZVV A;  3P91 A;  1AXC A;  1DML A;  3U5Z F;  3U60 F;  5IXA A;  5E0T A;  2NTI A;  5E0U A;  4CS5 A;  4YHR A;  3AIX A;  2HIK A;  1CZD A;  2NTI C;  5CFK A;  4L6P A;  3U61 F;  1W60 A;  1PLR A;  4RJF A;  1SXJ F;  3V62 B;  2HIK C;  1RXZ A;  1YYP A;  2AWA A;  5E0V A;  3FDS D;  3HSL X;  2NTI B;  1B8H A;  4ZTD A;  3AIZ A;  3AIX B;  2HIK B;  3VKX A;  5B7O A;  3GPM A;  2IZO C;  3P83 A;  2AVT A;  1U76 A;  3AIZ C;  1UL1 A;  3F1W A;  3IFV A;  5JNE D;  1PLQ A;  2IJX A;  2IX2 A;  3FDS C;  2ZVM A;  3GPN A;  3TBL A;  3A1J C;  5IY4 A;  2IZO B;  4TR6 A;  2IX2 C;  1IZ4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...