1IZ5A

Pyrococcus furiosus pcna mutant (met73leu, asp143ala, asp147ala): orthorhombic form
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
245
structure length
240
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEEPELPFTAKVVVLGEVLKAAVKAASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
pubmed doi rcsb
molecule tags Dna binding protein
source organism Pyrococcus furiosus
molecule keywords Proliferating cell nuclear antigen
total genus 60
structure length 240
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1iz5A00
1YYPA 3I2MX 2ZVMA 3V61B 1RWZA 3V62B 2HIKA 1VYMA 2AWAA 3G65C 1PLRA 1B77A 2NTIC 1RXMA 3AIXA 5IXAA 2Z0LA 3AIZC 2IO4B 3P91A 3LX1A 5B7OA 1U7BA 5JNED 4HK1A 3WGWA 3IFVA 1GE8A 5IWDA 2HIIA 3A2FB 4ZTDA 1RXZA 2OD8A 2IJXA 3FDSC 3TBLA 1VYJA 4L60A 5AUJA 3U5ZF 2IZOC 1AXCA 1CZDA 1U76A 2IX2C 1DMLA 3G65B 3GPNA 2NTIB 1PLQA 2HIKC 3F1WA 3HI8A 1SXJF 3GGRA 5A6DA 3A1JA 2ZVLA 3AIXB 3LX2A 4CS5A 2ZVWA 3P83A 3U60F 4TR6A 5E0VA 2HIIC 3HSLX 3A1JC 2IZOB 4YHRA 3P87A 2IX2B 2AVTA 5DAIA 1IZ4A 4RJFA 3G65A 1UD9A 5CFKA 2ZVKA 2IO4A 1T6LA 1IZ5A 2HIKB 5HACA 5DA7A 5IY4A 3AIZA 3K4XA 5H0TA 3GGRC 1UL1A 1B8HA 3GGRB 1W60A 2HIIB 3A1JB 3FDSD 4L6PA 5E0TA 1ISQA 5E0UA 4D2GA 3GPMA 3U61F 2NTIA 2IX2A 2ZVVA 3VKXA 3V60B
chains in the Genus database with same CATH superfamily
1YYPA 3I2MX 2ZVMA 3V61B 1RWZA 3V62B 2HIKA 1VYMA 2AWAA 3G65C 1PLRA 1B77A 2NTIC 1RXMA 3AIXA 5IXAA 2Z0LA 3AIZC 2IO4B 3P91A 3LX1A 5B7OA 1U7BA 5JNED 4HK1A 3WGWA 3IFVA 1GE8A 5IWDA 2HIIA 3A2FB 4ZTDA 1RXZA 2OD8A 2IJXA 3FDSC 3TBLA 1VYJA 4L60A 5AUJA 3U5ZF 2IZOC 1AXCA 1CZDA 1U76A 2IX2C 1DMLA 3G65B 3GPNA 2NTIB 1PLQA 2HIKC 3F1WA 3HI8A 1SXJF 3GGRA 5A6DA 3A1JA 2ZVLA 3AIXB 3LX2A 4CS5A 2ZVWA 3P83A 3U60F 4TR6A 5E0VA 2HIIC 3HSLX 3A1JC 2IZOB 4YHRA 3P87A 2IX2B 2AVTA 5DAIA 1IZ4A 4RJFA 3G65A 1UD9A 5CFKA 2ZVKA 2IO4A 1T6LA 1IZ5A 2HIKB 5HACA 5DA7A 5IY4A 3AIZA 3K4XA 5H0TA 3GGRC 1UL1A 1B8HA 3GGRB 1W60A 2HIIB 3A1JB 3FDSD 4L6PA 5E0TA 1ISQA 5E0UA 4D2GA 3GPMA 3U61F 2NTIA 2IX2A 2ZVVA 3VKXA 3V60B
chains in the Genus database with same CATH topology
1YYPA 3I2MX 2ZVMA 3V61B 1RWZA 3V62B 2HIKA 1VYMA 2AWAA 3G65C 1PLRA 1B77A 2NTIC 1RXMA 3AIXA 5IXAA 2Z0LA 3AIZC 2IO4B 3P91A 3LX1A 5B7OA 1U7BA 5JNED 4HK1A 3WGWA 3IFVA 1GE8A 5IWDA 2HIIA 3A2FB 4ZTDA 1RXZA 2OD8A 2IJXA 3FDSC 3TBLA 1VYJA 4L60A 5AUJA 3U5ZF 2IZOC 1AXCA 1CZDA 1U76A 2IX2C 1DMLA 3G65B 3GPNA 2NTIB 1PLQA 2HIKC 3F1WA 3HI8A 1SXJF 3GGRA 5A6DA 3A1JA 2ZVLA 3AIXB 3LX2A 4CS5A 2ZVWA 3P83A 3U60F 4TR6A 5E0VA 2HIIC 3HSLX 3A1JC 2IZOB 4YHRA 3P87A 2IX2B 2AVTA 5DAIA 1IZ4A 4RJFA 3G65A 1UD9A 5CFKA 2ZVKA 2IO4A 1T6LA 1IZ5A 2HIKB 5HACA 5DA7A 5IY4A 3AIZA 3K4XA 5H0TA 3GGRC 1UL1A 1B8HA 3GGRB 1W60A 2HIIB 3A1JB 3FDSD 4L6PA 5E0TA 1ISQA 5E0UA 4D2GA 3GPMA 3U61F 2NTIA 2IX2A 2ZVVA 3VKXA 3V60B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YYP A;  3I2M X;  2ZVM A;  3V61 B;  1RWZ A;  3V62 B;  2HIK A;  1VYM A;  2AWA A;  3G65 C;  1PLR A;  1B77 A;  2NTI C;  1RXM A;  3AIX A;  5IXA A;  2Z0L A;  3AIZ C;  2IO4 B;  3P91 A;  3LX1 A;  5B7O A;  1U7B A;  5JNE D;  4HK1 A;  3WGW A;  3IFV A;  1GE8 A;  5IWD A;  2HII A;  3A2F B;  4ZTD A;  1RXZ A;  2OD8 A;  2IJX A;  3FDS C;  3TBL A;  1VYJ A;  4L60 A;  5AUJ A;  3U5Z F;  2IZO C;  1AXC A;  1CZD A;  1U76 A;  2IX2 C;  1DML A;  3G65 B;  3GPN A;  2NTI B;  1PLQ A;  2HIK C;  3F1W A;  3HI8 A;  1SXJ F;  3GGR A;  5A6D A;  3A1J A;  2ZVL A;  3AIX B;  3LX2 A;  4CS5 A;  2ZVW A;  3P83 A;  3U60 F;  4TR6 A;  5E0V A;  2HII C;  3HSL X;  3A1J C;  2IZO B;  4YHR A;  3P87 A;  2IX2 B;  2AVT A;  5DAI A;  1IZ4 A;  4RJF A;  3G65 A;  1UD9 A;  5CFK A;  2ZVK A;  2IO4 A;  1T6L A;  1IZ5 A;  2HIK B;  5HAC A;  5DA7 A;  5IY4 A;  3AIZ A;  3K4X A;  5H0T A;  3GGR C;  1UL1 A;  1B8H A;  3GGR B;  1W60 A;  2HII B;  3A1J B;  3FDS D;  4L6P A;  5E0T A;  1ISQ A;  5E0U A;  4D2G A;  3GPM A;  3U61 F;  2NTI A;  2IX2 A;  2ZVV A;  3VKX A;  3V60 B; 
#chains in the Genus database with same CATH topology
 1YYP A;  3I2M X;  2ZVM A;  3V61 B;  1RWZ A;  3V62 B;  2HIK A;  1VYM A;  2AWA A;  3G65 C;  1PLR A;  1B77 A;  2NTI C;  1RXM A;  3AIX A;  5IXA A;  2Z0L A;  3AIZ C;  2IO4 B;  3P91 A;  3LX1 A;  5B7O A;  1U7B A;  5JNE D;  4HK1 A;  3WGW A;  3IFV A;  1GE8 A;  5IWD A;  2HII A;  3A2F B;  4ZTD A;  1RXZ A;  2OD8 A;  2IJX A;  3FDS C;  3TBL A;  1VYJ A;  4L60 A;  5AUJ A;  3U5Z F;  2IZO C;  1AXC A;  1CZD A;  1U76 A;  2IX2 C;  1DML A;  3G65 B;  3GPN A;  2NTI B;  1PLQ A;  2HIK C;  3F1W A;  3HI8 A;  1SXJ F;  3GGR A;  5A6D A;  3A1J A;  2ZVL A;  3AIX B;  3LX2 A;  4CS5 A;  2ZVW A;  3P83 A;  3U60 F;  4TR6 A;  5E0V A;  2HII C;  3HSL X;  3A1J C;  2IZO B;  4YHR A;  3P87 A;  2IX2 B;  2AVT A;  5DAI A;  1IZ4 A;  4RJF A;  3G65 A;  1UD9 A;  5CFK A;  2ZVK A;  2IO4 A;  1T6L A;  1IZ5 A;  2HIK B;  5HAC A;  5DA7 A;  5IY4 A;  3AIZ A;  3K4X A;  5H0T A;  3GGR C;  1UL1 A;  1B8H A;  3GGR B;  1W60 A;  2HII B;  3A1J B;  3FDS D;  4L6P A;  5E0T A;  1ISQ A;  5E0U A;  4D2G A;  3GPM A;  3U61 F;  2NTI A;  2IX2 A;  2ZVV A;  3VKX A;  3V60 B; 
#chains in the Genus database with same CATH homology
 1YYP A;  3I2M X;  2ZVM A;  3V61 B;  1RWZ A;  3V62 B;  2HIK A;  1VYM A;  2AWA A;  3G65 C;  1PLR A;  1B77 A;  2NTI C;  1RXM A;  3AIX A;  5IXA A;  2Z0L A;  3AIZ C;  2IO4 B;  3P91 A;  3LX1 A;  5B7O A;  1U7B A;  5JNE D;  4HK1 A;  3WGW A;  3IFV A;  1GE8 A;  5IWD A;  2HII A;  3A2F B;  4ZTD A;  1RXZ A;  2OD8 A;  2IJX A;  3FDS C;  3TBL A;  1VYJ A;  4L60 A;  5AUJ A;  3U5Z F;  2IZO C;  1AXC A;  1CZD A;  1U76 A;  2IX2 C;  1DML A;  3G65 B;  3GPN A;  2NTI B;  1PLQ A;  2HIK C;  3F1W A;  3HI8 A;  1SXJ F;  3GGR A;  5A6D A;  3A1J A;  2ZVL A;  3AIX B;  3LX2 A;  4CS5 A;  2ZVW A;  3P83 A;  3U60 F;  4TR6 A;  5E0V A;  2HII C;  3HSL X;  3A1J C;  2IZO B;  4YHR A;  3P87 A;  2IX2 B;  2AVT A;  5DAI A;  1IZ4 A;  4RJF A;  3G65 A;  1UD9 A;  5CFK A;  2ZVK A;  2IO4 A;  1T6L A;  1IZ5 A;  2HIK B;  5HAC A;  5DA7 A;  5IY4 A;  3AIZ A;  3K4X A;  5H0T A;  3GGR C;  1UL1 A;  1B8H A;  3GGR B;  1W60 A;  2HII B;  3A1J B;  3FDS D;  4L6P A;  5E0T A;  1ISQ A;  5E0U A;  4D2G A;  3GPM A;  3U61 F;  2NTI A;  2IX2 A;  2ZVV A;  3VKX A;  3V60 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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