1JFZA

Crystal structure of mn(ii)-complex of rnase iii endonuclease domain from aquifex aeolicus at 2.10 angstrom resolution
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
148
structure length
148
Chain Sequence
GMKMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFIVDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKINETIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords RIBONUCLEASE III
total genus 53
structure length 148
sequence length 148
chains with identical sequence B, C, D
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2001-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00636 Ribonuclease_3 Ribonuclease III domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1520.10 Mainly Alpha Orthogonal Bundle Ribonuclease iii, N-terminal Endonuclease Domain; Chain A Ribonuclease III domain 1jfzA00
3RV1A 1YYOA 4M2ZA 2NUGA 4OUNA 2EZ6A 1RC7A 1O0WA 3O2RA 1RC5A 3C4BA 2NUFA 4M30A 4OOGC 1YYWA 1JFZA 1I4SA 2NUEA 2EB1A 1YZ9A 2QVWA 3RV0A 1YYKA 3O2RB 3N3WA 2FFLA 2GSLA 1U61A 3C4TA 2A11A
chains in the Genus database with same CATH superfamily
3RV1A 1YYOA 4M2ZA 2NUGA 4OUNA 2EZ6A 1RC7A 1O0WA 3O2RA 1RC5A 3C4BA 2NUFA 4M30A 4OOGC 1YYWA 1JFZA 1I4SA 2NUEA 2EB1A 1ZTDA 2QVWA 1YZ9A 3RV0A 1YYKA 3O2RB 3N3WA 2FFLA 2GSLA 1U61A 3C4TA 2A11A
chains in the Genus database with same CATH topology
3RV1A 1YYOA 4M2ZA 2NUGA 4OUNA 2EZ6A 1RC7A 1O0WA 3O2RA 1RC5A 3C4BA 2NUFA 4M30A 4OOGC 1YYWA 1JFZA 1I4SA 2NUEA 2EB1A 1YZ9A 2QVWA 3RV0A 1YYKA 3O2RB 3N3WA 2FFLA 2GSLA 1U61A 3C4TA 2A11A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RV1 A;  1YYO A;  4M2Z A;  2NUG A;  4OUN A;  2EZ6 A;  1RC7 A;  1O0W A;  3O2R A;  1RC5 A;  3C4B A;  2NUF A;  4M30 A;  4OOG C;  1YYW A;  1JFZ A;  1I4S A;  2NUE A;  2EB1 A;  1YZ9 A;  2QVW A;  3RV0 A;  1YYK A;  3O2R B;  3N3W A;  2FFL A;  2GSL A;  1U61 A;  3C4T A;  2A11 A; 
#chains in the Genus database with same CATH topology
 3RV1 A;  1YYO A;  4M2Z A;  2NUG A;  4OUN A;  2EZ6 A;  1RC7 A;  1O0W A;  3O2R A;  1RC5 A;  3C4B A;  2NUF A;  4M30 A;  4OOG C;  1YYW A;  1JFZ A;  1I4S A;  2NUE A;  2EB1 A;  1ZTD A;  2QVW A;  1YZ9 A;  3RV0 A;  1YYK A;  3O2R B;  3N3W A;  2FFL A;  2GSL A;  1U61 A;  3C4T A;  2A11 A; 
#chains in the Genus database with same CATH homology
 3RV1 A;  1YYO A;  4M2Z A;  2NUG A;  4OUN A;  2EZ6 A;  1RC7 A;  1O0W A;  3O2R A;  1RC5 A;  3C4B A;  2NUF A;  4M30 A;  4OOG C;  1YYW A;  1JFZ A;  1I4S A;  2NUE A;  2EB1 A;  1YZ9 A;  2QVW A;  3RV0 A;  1YYK A;  3O2R B;  3N3W A;  2FFL A;  2GSL A;  1U61 A;  3C4T A;  2A11 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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