1PLRA

Crystal structure of the eukaryotic dna polymerase processivity factor pcna
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
258
structure length
258
Chain Sequence
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFNDEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna-binding
source organism Saccharomyces cerevisiae
publication title Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
pubmed doi rcsb
molecule keywords PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
total genus 58
structure length 258
sequence length 258
ec nomenclature
pdb deposition date 1995-01-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1plrA00
2HIKC 2ZVKA 5DA7A 4YHRA 1SXJF 2NTIA 3K4XA 3AIXB 5B7OA 3V61B 4ZTDA 3LX1A 2ZVLA 3A2FB 2ZVWA 2IX2C 1RXZA 1IZ4A 5DAIA 1W60A 2IZOB 5AUJA 1YYPA 3G65B 1PLQA 3P91A 5H0TA 1RWZA 1ISQA 3GGRA 2IO4A 2ZVMA 1RXMA 3A1JB 5A6DA 4HK1A 3LX2A 2HIKA 2Z0LA 2IZOC 4D2GA 3G65C 5CFKA 5IY4A 1IZ5A 2HIIB 3P87A 1B77A 3IFVA 5HACA 1B8HA 2IX2A 1CZDA 2OD8A 3VKXA 1PLRA 3F1WA 2NTIB 3AIXA 1GE8A 4RJFA 1DMLA 3HSLX 2HIIC 3V62B 3AIZC 1AXCA 1U76A 2ZVVA 5IXAA 3GPMA 1U7BA 2IJXA 3G65A 5E0TA 3WGWA 2NTIC 3HI8A 3A1JC 3GGRB 1T6LA 2IO4B 4L6PA 2AVTA 3A1JA 3P83A 5E0VA 5E0UA 4CS5A 2HIKB 5JNED 3U61F 2AWAA 3V60B 1VYJA 3I2MX 3FDSC 3TBLA 1UL1A 5IWDA 4TR6A 1VYMA 2HIIA 1UD9A 3GGRC 4L60A 3U60F 3AIZA 3FDSD 3GPNA 2IX2B 3U5ZF
chains in the Genus database with same CATH superfamily
2HIKC 2ZVKA 5DA7A 4YHRA 1SXJF 2NTIA 3K4XA 3AIXB 5B7OA 3V61B 4ZTDA 3LX1A 2ZVLA 3A2FB 2ZVWA 2IX2C 1RXZA 1IZ4A 5DAIA 1W60A 2IZOB 5AUJA 1YYPA 3G65B 1PLQA 3P91A 5H0TA 1RWZA 1ISQA 3GGRA 2IO4A 2ZVMA 1RXMA 3A1JB 5A6DA 4HK1A 3LX2A 2HIKA 2Z0LA 2IZOC 4D2GA 3G65C 5CFKA 5IY4A 1IZ5A 2HIIB 3P87A 1B77A 3IFVA 5HACA 1B8HA 2IX2A 1CZDA 2OD8A 3VKXA 1PLRA 3F1WA 2NTIB 3AIXA 1GE8A 4RJFA 1DMLA 3HSLX 2HIIC 3V62B 3AIZC 1AXCA 1U76A 2ZVVA 5IXAA 3GPMA 1U7BA 2IJXA 3G65A 5E0TA 3WGWA 2NTIC 3HI8A 3A1JC 3GGRB 1T6LA 2IO4B 4L6PA 2AVTA 3A1JA 3P83A 5E0VA 5E0UA 4CS5A 2HIKB 5JNED 3U61F 2AWAA 3V60B 1VYJA 3I2MX 3FDSC 3TBLA 1UL1A 5IWDA 4TR6A 1VYMA 2HIIA 1UD9A 3GGRC 4L60A 3U60F 3AIZA 3FDSD 3GPNA 2IX2B 3U5ZF
chains in the Genus database with same CATH topology
2HIKC 2ZVKA 5DA7A 4YHRA 1SXJF 2NTIA 3K4XA 3AIXB 5B7OA 3V61B 4ZTDA 3LX1A 2ZVLA 3A2FB 2ZVWA 2IX2C 1RXZA 1IZ4A 5DAIA 1W60A 2IZOB 5AUJA 1YYPA 3G65B 1PLQA 3P91A 5H0TA 1RWZA 1ISQA 3GGRA 2IO4A 2ZVMA 1RXMA 3A1JB 5A6DA 4HK1A 3LX2A 2HIKA 2Z0LA 2IZOC 4D2GA 3G65C 5CFKA 5IY4A 1IZ5A 2HIIB 3P87A 1B77A 3IFVA 5HACA 1B8HA 2IX2A 1CZDA 2OD8A 3VKXA 1PLRA 3F1WA 2NTIB 3AIXA 1GE8A 4RJFA 1DMLA 3HSLX 2HIIC 3V62B 3AIZC 1AXCA 1U76A 2ZVVA 5IXAA 3GPMA 1U7BA 2IJXA 3G65A 5E0TA 3WGWA 2NTIC 3HI8A 3A1JC 3GGRB 1T6LA 2IO4B 4L6PA 2AVTA 3A1JA 3P83A 5E0VA 5E0UA 4CS5A 2HIKB 5JNED 3U61F 2AWAA 3V60B 1VYJA 3I2MX 3FDSC 3TBLA 1UL1A 5IWDA 4TR6A 1VYMA 2HIIA 1UD9A 3GGRC 4L60A 3U60F 3AIZA 3FDSD 3GPNA 2IX2B 3U5ZF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HIK C;  2ZVK A;  5DA7 A;  4YHR A;  1SXJ F;  2NTI A;  3K4X A;  3AIX B;  5B7O A;  3V61 B;  4ZTD A;  3LX1 A;  2ZVL A;  3A2F B;  2ZVW A;  2IX2 C;  1RXZ A;  1IZ4 A;  5DAI A;  1W60 A;  2IZO B;  5AUJ A;  1YYP A;  3G65 B;  1PLQ A;  3P91 A;  5H0T A;  1RWZ A;  1ISQ A;  3GGR A;  2IO4 A;  2ZVM A;  1RXM A;  3A1J B;  5A6D A;  4HK1 A;  3LX2 A;  2HIK A;  2Z0L A;  2IZO C;  4D2G A;  3G65 C;  5CFK A;  5IY4 A;  1IZ5 A;  2HII B;  3P87 A;  1B77 A;  3IFV A;  5HAC A;  1B8H A;  2IX2 A;  1CZD A;  2OD8 A;  3VKX A;  1PLR A;  3F1W A;  2NTI B;  3AIX A;  1GE8 A;  4RJF A;  1DML A;  3HSL X;  2HII C;  3V62 B;  3AIZ C;  1AXC A;  1U76 A;  2ZVV A;  5IXA A;  3GPM A;  1U7B A;  2IJX A;  3G65 A;  5E0T A;  3WGW A;  2NTI C;  3HI8 A;  3A1J C;  3GGR B;  1T6L A;  2IO4 B;  4L6P A;  2AVT A;  3A1J A;  3P83 A;  5E0V A;  5E0U A;  4CS5 A;  2HIK B;  5JNE D;  3U61 F;  2AWA A;  3V60 B;  1VYJ A;  3I2M X;  3FDS C;  3TBL A;  1UL1 A;  5IWD A;  4TR6 A;  1VYM A;  2HII A;  1UD9 A;  3GGR C;  4L60 A;  3U60 F;  3AIZ A;  3FDS D;  3GPN A;  2IX2 B;  3U5Z F; 
#chains in the Genus database with same CATH topology
 2HIK C;  2ZVK A;  5DA7 A;  4YHR A;  1SXJ F;  2NTI A;  3K4X A;  3AIX B;  5B7O A;  3V61 B;  4ZTD A;  3LX1 A;  2ZVL A;  3A2F B;  2ZVW A;  2IX2 C;  1RXZ A;  1IZ4 A;  5DAI A;  1W60 A;  2IZO B;  5AUJ A;  1YYP A;  3G65 B;  1PLQ A;  3P91 A;  5H0T A;  1RWZ A;  1ISQ A;  3GGR A;  2IO4 A;  2ZVM A;  1RXM A;  3A1J B;  5A6D A;  4HK1 A;  3LX2 A;  2HIK A;  2Z0L A;  2IZO C;  4D2G A;  3G65 C;  5CFK A;  5IY4 A;  1IZ5 A;  2HII B;  3P87 A;  1B77 A;  3IFV A;  5HAC A;  1B8H A;  2IX2 A;  1CZD A;  2OD8 A;  3VKX A;  1PLR A;  3F1W A;  2NTI B;  3AIX A;  1GE8 A;  4RJF A;  1DML A;  3HSL X;  2HII C;  3V62 B;  3AIZ C;  1AXC A;  1U76 A;  2ZVV A;  5IXA A;  3GPM A;  1U7B A;  2IJX A;  3G65 A;  5E0T A;  3WGW A;  2NTI C;  3HI8 A;  3A1J C;  3GGR B;  1T6L A;  2IO4 B;  4L6P A;  2AVT A;  3A1J A;  3P83 A;  5E0V A;  5E0U A;  4CS5 A;  2HIK B;  5JNE D;  3U61 F;  2AWA A;  3V60 B;  1VYJ A;  3I2M X;  3FDS C;  3TBL A;  1UL1 A;  5IWD A;  4TR6 A;  1VYM A;  2HII A;  1UD9 A;  3GGR C;  4L60 A;  3U60 F;  3AIZ A;  3FDS D;  3GPN A;  2IX2 B;  3U5Z F; 
#chains in the Genus database with same CATH homology
 2HIK C;  2ZVK A;  5DA7 A;  4YHR A;  1SXJ F;  2NTI A;  3K4X A;  3AIX B;  5B7O A;  3V61 B;  4ZTD A;  3LX1 A;  2ZVL A;  3A2F B;  2ZVW A;  2IX2 C;  1RXZ A;  1IZ4 A;  5DAI A;  1W60 A;  2IZO B;  5AUJ A;  1YYP A;  3G65 B;  1PLQ A;  3P91 A;  5H0T A;  1RWZ A;  1ISQ A;  3GGR A;  2IO4 A;  2ZVM A;  1RXM A;  3A1J B;  5A6D A;  4HK1 A;  3LX2 A;  2HIK A;  2Z0L A;  2IZO C;  4D2G A;  3G65 C;  5CFK A;  5IY4 A;  1IZ5 A;  2HII B;  3P87 A;  1B77 A;  3IFV A;  5HAC A;  1B8H A;  2IX2 A;  1CZD A;  2OD8 A;  3VKX A;  1PLR A;  3F1W A;  2NTI B;  3AIX A;  1GE8 A;  4RJF A;  1DML A;  3HSL X;  2HII C;  3V62 B;  3AIZ C;  1AXC A;  1U76 A;  2ZVV A;  5IXA A;  3GPM A;  1U7B A;  2IJX A;  3G65 A;  5E0T A;  3WGW A;  2NTI C;  3HI8 A;  3A1J C;  3GGR B;  1T6L A;  2IO4 B;  4L6P A;  2AVT A;  3A1J A;  3P83 A;  5E0V A;  5E0U A;  4CS5 A;  2HIK B;  5JNE D;  3U61 F;  2AWA A;  3V60 B;  1VYJ A;  3I2M X;  3FDS C;  3TBL A;  1UL1 A;  5IWD A;  4TR6 A;  1VYM A;  2HII A;  1UD9 A;  3GGR C;  4L60 A;  3U60 F;  3AIZ A;  3FDS D;  3GPN A;  2IX2 B;  3U5Z F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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