1R8DA

Crystal structure of mtan bound to dna
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
109
structure length
109
Chain Sequence
MKYQVKQVAEISGVSIRTLHHYDNIELLNPSALTDAGYRLYSDADLERLQQILFFKEIGFRLDEIKEMLDHPNFDRKAALQSQKEILMKKKQRMDEMIQTIDRTLLSVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Bacillus subtilis
molecule keywords 26-MER
total genus 42
structure length 109
sequence length 109
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 1r8dA00
2ZHHA 4R24B 2VZ4A 3D6ZA 3Q3DA 3IAOA 3HH0A 5E01A 3GP4A 2DG6A 1Q08A 1Q05A 5D8CA 3Q5RA 1R8EA 1EXJA 3D71A 1Q06A 4WLSA 4WLWA 3D70A 1Q09A 2ZHGA 3Q1MA 3GPVA 5D90A 1EXIA 3UCSA 1Q07A 5I44A 4R4EA 3Q5SA 2JMLA 3D6YA 1R8DA 4R22B 5I41B 1JBGA 3Q2YA 4J2NA 3Q5PA 3QAOA 1Q0AA
chains in the Genus database with same CATH superfamily
4R24B 2VZ4A 3D6ZA 3Q3DA 1LX8A 4DCZA 3QAOA 3IAOA 3HH0A 2OG0A 5E01A 3GP4A 2DG6A 1Q08A 1Q05A 5D8CA 3Q5RA 1R8EA 1EXJA 2IEFA 3D71A 1Q06A 4WLSA 4WLWA 3D70A 1Q09A 2ZHGA 3Q1MA 3Q5PA 2KVVA 3GPVA 5D90A 1EXIA 3UCSA 1Q07A 1Y6UA 3EZ7A 3EZ9A 5I44A 4R4EA 3Q5SA 2JMLA 3EZ6A 1R8DA 3D6YA 4R22B 5I41B 1JBGA 3EZFA 4LHFA 1RH6A 3Q2YA 4J2NA 1PM6A 2ZHHA 1Q0AA 3EZ2A
chains in the Genus database with same CATH topology
4R24B 2VZ4A 3D6ZA 3Q3DA 1LX8A 4DCZA 3QAOA 3IAOA 3HH0A 2OG0A 5E01A 3GP4A 2DG6A 1Q08A 1Q05A 5D8CA 3Q5RA 1R8EA 1EXJA 2IEFA 3D71A 1Q06A 4WLSA 4WLWA 3D70A 1Q09A 2ZHGA 3Q1MA 3Q5PA 2KVVA 3GPVA 5D90A 1EXIA 3UCSA 1Q07A 1Y6UA 3EZ7A 3EZ9A 5I44A 4R4EA 3Q5SA 2JMLA 3EZ6A 1R8DA 3D6YA 4R22B 5I41B 1JBGA 3EZFA 4LHFA 1RH6A 3Q2YA 4J2NA 1PM6A 2ZHHA 1Q0AA 3EZ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZHH A;  4R24 B;  2VZ4 A;  3D6Z A;  3Q3D A;  3IAO A;  3HH0 A;  5E01 A;  3GP4 A;  2DG6 A;  1Q08 A;  1Q05 A;  5D8C A;  3Q5R A;  1R8E A;  1EXJ A;  3D71 A;  1Q06 A;  4WLS A;  4WLW A;  3D70 A;  1Q09 A;  2ZHG A;  3Q1M A;  3GPV A;  5D90 A;  1EXI A;  3UCS A;  1Q07 A;  5I44 A;  4R4E A;  3Q5S A;  2JML A;  3D6Y A;  1R8D A;  4R22 B;  5I41 B;  1JBG A;  3Q2Y A;  4J2N A;  3Q5P A;  3QAO A;  1Q0A A; 
#chains in the Genus database with same CATH topology
 4R24 B;  2VZ4 A;  3D6Z A;  3Q3D A;  1LX8 A;  4DCZ A;  3QAO A;  3IAO A;  3HH0 A;  2OG0 A;  5E01 A;  3GP4 A;  2DG6 A;  1Q08 A;  1Q05 A;  5D8C A;  3Q5R A;  1R8E A;  1EXJ A;  2IEF A;  3D71 A;  1Q06 A;  4WLS A;  4WLW A;  3D70 A;  1Q09 A;  2ZHG A;  3Q1M A;  3Q5P A;  2KVV A;  3GPV A;  5D90 A;  1EXI A;  3UCS A;  1Q07 A;  1Y6U A;  3EZ7 A;  3EZ9 A;  5I44 A;  4R4E A;  3Q5S A;  2JML A;  3EZ6 A;  1R8D A;  3D6Y A;  4R22 B;  5I41 B;  1JBG A;  3EZF A;  4LHF A;  1RH6 A;  3Q2Y A;  4J2N A;  1PM6 A;  2ZHH A;  1Q0A A;  3EZ2 A; 
#chains in the Genus database with same CATH homology
 4R24 B;  2VZ4 A;  3D6Z A;  3Q3D A;  1LX8 A;  4DCZ A;  3QAO A;  3IAO A;  3HH0 A;  2OG0 A;  5E01 A;  3GP4 A;  2DG6 A;  1Q08 A;  1Q05 A;  5D8C A;  3Q5R A;  1R8E A;  1EXJ A;  2IEF A;  3D71 A;  1Q06 A;  4WLS A;  4WLW A;  3D70 A;  1Q09 A;  2ZHG A;  3Q1M A;  3Q5P A;  2KVV A;  3GPV A;  5D90 A;  1EXI A;  3UCS A;  1Q07 A;  1Y6U A;  3EZ7 A;  3EZ9 A;  5I44 A;  4R4E A;  3Q5S A;  2JML A;  3EZ6 A;  1R8D A;  3D6Y A;  4R22 B;  5I41 B;  1JBG A;  3EZF A;  4LHF A;  1RH6 A;  3Q2Y A;  4J2N A;  1PM6 A;  2ZHH A;  1Q0A A;  3EZ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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