4WLWA

Crystal structure of the ag(i) (activator) form of e. coli cuer, a copper efflux regulator, bound to copa promoter dna
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
130
structure length
130
Chain Sequence
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna
molecule keywords HTH-type transcriptional regulator CueR
publication title TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
pubmed doi rcsb
source organism Escherichia coli
total genus 46
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 4wlwA00
2JMLA 1Q06A 5D8CA 1Q08A 2VZ4A 3Q1MA 3QAOA 4R22B 1Q05A 1Q09A 3GP4A 3D71A 1R8DA 1EXJA 4R4EA 3Q5PA 3Q3DA 3Q5SA 1JBGA 5D90A 5I41B 3HH0A 1EXIA 3D70A 4J2NA 3D6YA 3Q5RA 4WLWA 2DG6A 3Q2YA 5E01A 2ZHHA 1Q0AA 5I44A 2ZHGA 1Q07A 3D6ZA 4WLSA 3UCSA 4R24B 3IAOA 1R8EA 3GPVA
chains in the Genus database with same CATH superfamily
2JMLA 1Q06A 5D8CA 1Q08A 2VZ4A 3Q1MA 3QAOA 1Y6UA 4R22B 3EZFA 1Q05A 1Q09A 3EZ7A 3GP4A 3D71A 1R8DA 4R4EA 3Q5PA 1EXJA 4DCZA 3Q3DA 3Q5SA 3EZ6A 1RH6A 1JBGA 5D90A 5I41B 3EZ9A 2IEFA 3HH0A 1EXIA 3D70A 4J2NA 3D6YA 3Q5RA 4WLWA 3EZ2A 2DG6A 3Q2YA 2KVVA 5E01A 1R8EA 2ZHHA 1Q0AA 1LX8A 5I44A 2ZHGA 2OG0A 1PM6A 1Q07A 3D6ZA 4WLSA 3UCSA 4R24B 3IAOA 4LHFA 3GPVA
chains in the Genus database with same CATH topology
2JMLA 1Q06A 5D8CA 1Q08A 2VZ4A 3Q1MA 3QAOA 1Y6UA 4R22B 3EZFA 1Q05A 1Q09A 3EZ7A 3GP4A 3D71A 1R8DA 4R4EA 3Q5PA 1EXJA 4DCZA 3Q3DA 3Q5SA 3EZ6A 1RH6A 1JBGA 5D90A 5I41B 3EZ9A 2IEFA 3HH0A 1EXIA 3D70A 4J2NA 3D6YA 3Q5RA 4WLWA 3EZ2A 2DG6A 3Q2YA 2KVVA 5E01A 1R8EA 2ZHHA 1Q0AA 1LX8A 5I44A 2ZHGA 2OG0A 1PM6A 1Q07A 3D6ZA 4WLSA 3UCSA 4R24B 3IAOA 4LHFA 3GPVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JML A;  1Q06 A;  5D8C A;  1Q08 A;  2VZ4 A;  3Q1M A;  3QAO A;  4R22 B;  1Q05 A;  1Q09 A;  3GP4 A;  3D71 A;  1R8D A;  1EXJ A;  4R4E A;  3Q5P A;  3Q3D A;  3Q5S A;  1JBG A;  5D90 A;  5I41 B;  3HH0 A;  1EXI A;  3D70 A;  4J2N A;  3D6Y A;  3Q5R A;  4WLW A;  2DG6 A;  3Q2Y A;  5E01 A;  2ZHH A;  1Q0A A;  5I44 A;  2ZHG A;  1Q07 A;  3D6Z A;  4WLS A;  3UCS A;  4R24 B;  3IAO A;  1R8E A;  3GPV A; 
#chains in the Genus database with same CATH topology
 2JML A;  1Q06 A;  5D8C A;  1Q08 A;  2VZ4 A;  3Q1M A;  3QAO A;  1Y6U A;  4R22 B;  3EZF A;  1Q05 A;  1Q09 A;  3EZ7 A;  3GP4 A;  3D71 A;  1R8D A;  4R4E A;  3Q5P A;  1EXJ A;  4DCZ A;  3Q3D A;  3Q5S A;  3EZ6 A;  1RH6 A;  1JBG A;  5D90 A;  5I41 B;  3EZ9 A;  2IEF A;  3HH0 A;  1EXI A;  3D70 A;  4J2N A;  3D6Y A;  3Q5R A;  4WLW A;  3EZ2 A;  2DG6 A;  3Q2Y A;  2KVV A;  5E01 A;  1R8E A;  2ZHH A;  1Q0A A;  1LX8 A;  5I44 A;  2ZHG A;  2OG0 A;  1PM6 A;  1Q07 A;  3D6Z A;  4WLS A;  3UCS A;  4R24 B;  3IAO A;  4LHF A;  3GPV A; 
#chains in the Genus database with same CATH homology
 2JML A;  1Q06 A;  5D8C A;  1Q08 A;  2VZ4 A;  3Q1M A;  3QAO A;  1Y6U A;  4R22 B;  3EZF A;  1Q05 A;  1Q09 A;  3EZ7 A;  3GP4 A;  3D71 A;  1R8D A;  4R4E A;  3Q5P A;  1EXJ A;  4DCZ A;  3Q3D A;  3Q5S A;  3EZ6 A;  1RH6 A;  1JBG A;  5D90 A;  5I41 B;  3EZ9 A;  2IEF A;  3HH0 A;  1EXI A;  3D70 A;  4J2N A;  3D6Y A;  3Q5R A;  4WLW A;  3EZ2 A;  2DG6 A;  3Q2Y A;  2KVV A;  5E01 A;  1R8E A;  2ZHH A;  1Q0A A;  1LX8 A;  5I44 A;  2ZHG A;  2OG0 A;  1PM6 A;  1Q07 A;  3D6Z A;  4WLS A;  3UCS A;  4R24 B;  3IAO A;  4LHF A;  3GPV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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