5D8CA

Crystal structure of hinmlr, a merr family regulator lacking the sensor domain, bound to promoter dna
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
126
structure length
126
Chain Sequence
MTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKALGSVKAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords MerR family regulator protein
total genus 47
structure length 126
sequence length 126
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 5d8cA00
4R22B 2JMLA 4J2NA 2VZ4A 1Q09A 4R24B 3D71A 5E01A 3GPVA 5I41B 3GP4A 3D6ZA 3Q3DA 5D8CA 5D90A 3Q2YA 1R8DA 4WLWA 4WLSA 3IAOA 1Q05A 3D6YA 3HH0A 2ZHHA 3QAOA 3Q1MA 3D70A 1Q08A 1Q06A 1EXIA 4R4EA 1Q07A 3UCSA 3Q5RA 1Q0AA 2DG6A 3Q5SA 2ZHGA 1JBGA 1EXJA 5I44A 3Q5PA 1R8EA
chains in the Genus database with same CATH superfamily
1PM6A 4R22B 2JMLA 4J2NA 2VZ4A 1Q09A 4R24B 3D71A 5E01A 2IEFA 3GPVA 2KVVA 5I41B 3GP4A 3D6ZA 3Q3DA 5D8CA 5D90A 2OG0A 3Q2YA 1R8DA 4WLWA 4WLSA 1RH6A 3IAOA 1Q05A 3D6YA 3HH0A 3EZ6A 1LX8A 2ZHHA 1R8EA 3EZ2A 3QAOA 4LHFA 4DCZA 3Q1MA 3D70A 1Q08A 1Q06A 1EXIA 4R4EA 1Q07A 1Y6UA 3EZ9A 1Q0AA 2DG6A 3UCSA 3Q5RA 2ZHGA 3Q5SA 1JBGA 1EXJA 5I44A 3Q5PA 3EZFA 3EZ7A
chains in the Genus database with same CATH topology
1PM6A 4R22B 2JMLA 4J2NA 2VZ4A 1Q09A 4R24B 3D71A 5E01A 2IEFA 3GPVA 2KVVA 5I41B 3GP4A 3D6ZA 3Q3DA 5D8CA 5D90A 2OG0A 3Q2YA 1R8DA 4WLWA 4WLSA 1RH6A 3IAOA 1Q05A 3D6YA 3HH0A 3EZ6A 1LX8A 2ZHHA 1R8EA 3EZ2A 3QAOA 4LHFA 4DCZA 3Q1MA 3D70A 1Q08A 1Q06A 1EXIA 4R4EA 1Q07A 1Y6UA 3EZ9A 1Q0AA 2DG6A 3UCSA 3Q5RA 2ZHGA 3Q5SA 1JBGA 1EXJA 5I44A 3Q5PA 3EZFA 3EZ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R22 B;  2JML A;  4J2N A;  2VZ4 A;  1Q09 A;  4R24 B;  3D71 A;  5E01 A;  3GPV A;  5I41 B;  3GP4 A;  3D6Z A;  3Q3D A;  5D8C A;  5D90 A;  3Q2Y A;  1R8D A;  4WLW A;  4WLS A;  3IAO A;  1Q05 A;  3D6Y A;  3HH0 A;  2ZHH A;  3QAO A;  3Q1M A;  3D70 A;  1Q08 A;  1Q06 A;  1EXI A;  4R4E A;  1Q07 A;  3UCS A;  3Q5R A;  1Q0A A;  2DG6 A;  3Q5S A;  2ZHG A;  1JBG A;  1EXJ A;  5I44 A;  3Q5P A;  1R8E A; 
#chains in the Genus database with same CATH topology
 1PM6 A;  4R22 B;  2JML A;  4J2N A;  2VZ4 A;  1Q09 A;  4R24 B;  3D71 A;  5E01 A;  2IEF A;  3GPV A;  2KVV A;  5I41 B;  3GP4 A;  3D6Z A;  3Q3D A;  5D8C A;  5D90 A;  2OG0 A;  3Q2Y A;  1R8D A;  4WLW A;  4WLS A;  1RH6 A;  3IAO A;  1Q05 A;  3D6Y A;  3HH0 A;  3EZ6 A;  1LX8 A;  2ZHH A;  1R8E A;  3EZ2 A;  3QAO A;  4LHF A;  4DCZ A;  3Q1M A;  3D70 A;  1Q08 A;  1Q06 A;  1EXI A;  4R4E A;  1Q07 A;  1Y6U A;  3EZ9 A;  1Q0A A;  2DG6 A;  3UCS A;  3Q5R A;  2ZHG A;  3Q5S A;  1JBG A;  1EXJ A;  5I44 A;  3Q5P A;  3EZF A;  3EZ7 A; 
#chains in the Genus database with same CATH homology
 1PM6 A;  4R22 B;  2JML A;  4J2N A;  2VZ4 A;  1Q09 A;  4R24 B;  3D71 A;  5E01 A;  2IEF A;  3GPV A;  2KVV A;  5I41 B;  3GP4 A;  3D6Z A;  3Q3D A;  5D8C A;  5D90 A;  2OG0 A;  3Q2Y A;  1R8D A;  4WLW A;  4WLS A;  1RH6 A;  3IAO A;  1Q05 A;  3D6Y A;  3HH0 A;  3EZ6 A;  1LX8 A;  2ZHH A;  1R8E A;  3EZ2 A;  3QAO A;  4LHF A;  4DCZ A;  3Q1M A;  3D70 A;  1Q08 A;  1Q06 A;  1EXI A;  4R4E A;  1Q07 A;  1Y6U A;  3EZ9 A;  1Q0A A;  2DG6 A;  3UCS A;  3Q5R A;  2ZHG A;  3Q5S A;  1JBG A;  1EXJ A;  5I44 A;  3Q5P A;  3EZF A;  3EZ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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