1RXMA

C-terminal region of fen-1 bound to a. fulgidus pcna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
245
structure length
245
Chain Sequence
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
pubmed doi rcsb
molecule tags Replication
source organism Archaeoglobus fulgidus
molecule keywords DNA polymerase sliding clamp
total genus 62
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2003-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1rxmA00
2IX2A 1RXMA 2ZVWA 3G65B 2HIKC 3LX2A 4ZTDA 1T6LA 2HIIB 1CZDA 2IO4A 1GE8A 1U7BA 2AWAA 4RJFA 4HK1A 2ZVMA 3FDSC 3VKXA 2Z0LA 2NTIA 3U61F 2OD8A 3I2MX 2HIIC 1B77A 5B7OA 1VYMA 1U76A 1B8HA 3AIZA 1YYPA 1PLRA 3AIXB 5IXAA 3V62B 4L60A 1IZ4A 2HIIA 3FDSD 3A1JA 3WGWA 3A2FB 2IZOB 3GPNA 3V61B 2HIKA 3G65C 3IFVA 5E0VA 2IJXA 3GGRB 1VYJA 4CS5A 1W60A 1RXZA 5H0TA 3TBLA 2IO4B 2IZOC 1AXCA 3G65A 4D2GA 1IZ5A 5CFKA 3U5ZF 3GGRC 2NTIB 5AUJA 3F1WA 5DA7A 3HSLX 5E0TA 4YHRA 2IX2B 5DAIA 3U60F 3HI8A 1ISQA 1PLQA 3GPMA 5HACA 3GGRA 1UD9A 1UL1A 4L6PA 3V60B 3LX1A 3A1JB 2NTIC 5E0UA 1DMLA 3P87A 5IWDA 2IX2C 3P91A 3AIXA 5A6DA 2HIKB 3K4XA 2ZVVA 2ZVLA 3AIZC 1SXJF 3P83A 4TR6A 5JNED 2ZVKA 5IY4A 1RWZA 3A1JC 2AVTA
chains in the Genus database with same CATH superfamily
2IX2A 1RXMA 2ZVWA 3G65B 2HIKC 3LX2A 4ZTDA 1T6LA 2HIIB 1CZDA 2IO4A 1GE8A 1U7BA 2AWAA 4RJFA 4HK1A 2ZVMA 3FDSC 3VKXA 2Z0LA 2NTIA 3U61F 2OD8A 3I2MX 2HIIC 1B77A 5B7OA 1VYMA 1U76A 1B8HA 3AIZA 1YYPA 1PLRA 3AIXB 5IXAA 3V62B 4L60A 1IZ4A 2HIIA 3FDSD 3A1JA 3WGWA 3A2FB 2IZOB 3GPNA 3V61B 2HIKA 3G65C 3IFVA 5E0VA 2IJXA 3GGRB 1VYJA 4CS5A 1W60A 1RXZA 5H0TA 3TBLA 2IO4B 2IZOC 1AXCA 3G65A 4D2GA 1IZ5A 5CFKA 3U5ZF 3GGRC 2NTIB 5AUJA 3F1WA 5DA7A 3HSLX 5E0TA 4YHRA 2IX2B 5DAIA 3U60F 3HI8A 1ISQA 1PLQA 3GPMA 5HACA 3GGRA 1UD9A 1UL1A 4L6PA 3V60B 3LX1A 3A1JB 2NTIC 5E0UA 1DMLA 3P87A 5IWDA 2IX2C 3P91A 3AIXA 5A6DA 2HIKB 3K4XA 2ZVVA 2ZVLA 3AIZC 1SXJF 3P83A 4TR6A 5JNED 2ZVKA 5IY4A 1RWZA 3A1JC 2AVTA
chains in the Genus database with same CATH topology
2IX2A 1RXMA 2ZVWA 3G65B 2HIKC 3LX2A 4ZTDA 1T6LA 2HIIB 1CZDA 2IO4A 1GE8A 1U7BA 2AWAA 4RJFA 4HK1A 2ZVMA 3FDSC 3VKXA 2Z0LA 2NTIA 3U61F 2OD8A 3I2MX 2HIIC 1B77A 5B7OA 1VYMA 1U76A 1B8HA 3AIZA 1YYPA 1PLRA 3AIXB 5IXAA 3V62B 4L60A 1IZ4A 2HIIA 3FDSD 3A1JA 3WGWA 3A2FB 2IZOB 3GPNA 3V61B 2HIKA 3G65C 3IFVA 5E0VA 2IJXA 3GGRB 1VYJA 4CS5A 1W60A 1RXZA 5H0TA 3TBLA 2IO4B 2IZOC 1AXCA 3G65A 4D2GA 1IZ5A 5CFKA 3U5ZF 3GGRC 2NTIB 5AUJA 3F1WA 5DA7A 3HSLX 5E0TA 4YHRA 2IX2B 5DAIA 3U60F 3HI8A 1ISQA 1PLQA 3GPMA 5HACA 3GGRA 1UD9A 1UL1A 4L6PA 3V60B 3LX1A 3A1JB 2NTIC 5E0UA 1DMLA 3P87A 5IWDA 2IX2C 3P91A 3AIXA 5A6DA 2HIKB 3K4XA 2ZVVA 2ZVLA 3AIZC 1SXJF 3P83A 4TR6A 5JNED 2ZVKA 5IY4A 1RWZA 3A1JC 2AVTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IX2 A;  1RXM A;  2ZVW A;  3G65 B;  2HIK C;  3LX2 A;  4ZTD A;  1T6L A;  2HII B;  1CZD A;  2IO4 A;  1GE8 A;  1U7B A;  2AWA A;  4RJF A;  4HK1 A;  2ZVM A;  3FDS C;  3VKX A;  2Z0L A;  2NTI A;  3U61 F;  2OD8 A;  3I2M X;  2HII C;  1B77 A;  5B7O A;  1VYM A;  1U76 A;  1B8H A;  3AIZ A;  1YYP A;  1PLR A;  3AIX B;  5IXA A;  3V62 B;  4L60 A;  1IZ4 A;  2HII A;  3FDS D;  3A1J A;  3WGW A;  3A2F B;  2IZO B;  3GPN A;  3V61 B;  2HIK A;  3G65 C;  3IFV A;  5E0V A;  2IJX A;  3GGR B;  1VYJ A;  4CS5 A;  1W60 A;  1RXZ A;  5H0T A;  3TBL A;  2IO4 B;  2IZO C;  1AXC A;  3G65 A;  4D2G A;  1IZ5 A;  5CFK A;  3U5Z F;  3GGR C;  2NTI B;  5AUJ A;  3F1W A;  5DA7 A;  3HSL X;  5E0T A;  4YHR A;  2IX2 B;  5DAI A;  3U60 F;  3HI8 A;  1ISQ A;  1PLQ A;  3GPM A;  5HAC A;  3GGR A;  1UD9 A;  1UL1 A;  4L6P A;  3V60 B;  3LX1 A;  3A1J B;  2NTI C;  5E0U A;  1DML A;  3P87 A;  5IWD A;  2IX2 C;  3P91 A;  3AIX A;  5A6D A;  2HIK B;  3K4X A;  2ZVV A;  2ZVL A;  3AIZ C;  1SXJ F;  3P83 A;  4TR6 A;  5JNE D;  2ZVK A;  5IY4 A;  1RWZ A;  3A1J C;  2AVT A; 
#chains in the Genus database with same CATH topology
 2IX2 A;  1RXM A;  2ZVW A;  3G65 B;  2HIK C;  3LX2 A;  4ZTD A;  1T6L A;  2HII B;  1CZD A;  2IO4 A;  1GE8 A;  1U7B A;  2AWA A;  4RJF A;  4HK1 A;  2ZVM A;  3FDS C;  3VKX A;  2Z0L A;  2NTI A;  3U61 F;  2OD8 A;  3I2M X;  2HII C;  1B77 A;  5B7O A;  1VYM A;  1U76 A;  1B8H A;  3AIZ A;  1YYP A;  1PLR A;  3AIX B;  5IXA A;  3V62 B;  4L60 A;  1IZ4 A;  2HII A;  3FDS D;  3A1J A;  3WGW A;  3A2F B;  2IZO B;  3GPN A;  3V61 B;  2HIK A;  3G65 C;  3IFV A;  5E0V A;  2IJX A;  3GGR B;  1VYJ A;  4CS5 A;  1W60 A;  1RXZ A;  5H0T A;  3TBL A;  2IO4 B;  2IZO C;  1AXC A;  3G65 A;  4D2G A;  1IZ5 A;  5CFK A;  3U5Z F;  3GGR C;  2NTI B;  5AUJ A;  3F1W A;  5DA7 A;  3HSL X;  5E0T A;  4YHR A;  2IX2 B;  5DAI A;  3U60 F;  3HI8 A;  1ISQ A;  1PLQ A;  3GPM A;  5HAC A;  3GGR A;  1UD9 A;  1UL1 A;  4L6P A;  3V60 B;  3LX1 A;  3A1J B;  2NTI C;  5E0U A;  1DML A;  3P87 A;  5IWD A;  2IX2 C;  3P91 A;  3AIX A;  5A6D A;  2HIK B;  3K4X A;  2ZVV A;  2ZVL A;  3AIZ C;  1SXJ F;  3P83 A;  4TR6 A;  5JNE D;  2ZVK A;  5IY4 A;  1RWZ A;  3A1J C;  2AVT A; 
#chains in the Genus database with same CATH homology
 2IX2 A;  1RXM A;  2ZVW A;  3G65 B;  2HIK C;  3LX2 A;  4ZTD A;  1T6L A;  2HII B;  1CZD A;  2IO4 A;  1GE8 A;  1U7B A;  2AWA A;  4RJF A;  4HK1 A;  2ZVM A;  3FDS C;  3VKX A;  2Z0L A;  2NTI A;  3U61 F;  2OD8 A;  3I2M X;  2HII C;  1B77 A;  5B7O A;  1VYM A;  1U76 A;  1B8H A;  3AIZ A;  1YYP A;  1PLR A;  3AIX B;  5IXA A;  3V62 B;  4L60 A;  1IZ4 A;  2HII A;  3FDS D;  3A1J A;  3WGW A;  3A2F B;  2IZO B;  3GPN A;  3V61 B;  2HIK A;  3G65 C;  3IFV A;  5E0V A;  2IJX A;  3GGR B;  1VYJ A;  4CS5 A;  1W60 A;  1RXZ A;  5H0T A;  3TBL A;  2IO4 B;  2IZO C;  1AXC A;  3G65 A;  4D2G A;  1IZ5 A;  5CFK A;  3U5Z F;  3GGR C;  2NTI B;  5AUJ A;  3F1W A;  5DA7 A;  3HSL X;  5E0T A;  4YHR A;  2IX2 B;  5DAI A;  3U60 F;  3HI8 A;  1ISQ A;  1PLQ A;  3GPM A;  5HAC A;  3GGR A;  1UD9 A;  1UL1 A;  4L6P A;  3V60 B;  3LX1 A;  3A1J B;  2NTI C;  5E0U A;  1DML A;  3P87 A;  5IWD A;  2IX2 C;  3P91 A;  3AIX A;  5A6D A;  2HIK B;  3K4X A;  2ZVV A;  2ZVL A;  3AIZ C;  1SXJ F;  3P83 A;  4TR6 A;  5JNE D;  2ZVK A;  5IY4 A;  1RWZ A;  3A1J C;  2AVT A; 
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similar chains in the Genus database (?% sequence similarity)
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