1RXMA

C-terminal region of fen-1 bound to a. fulgidus pcna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
245
structure length
245
Chain Sequence
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
pubmed doi rcsb
molecule tags Replication
source organism Archaeoglobus fulgidus
molecule keywords DNA polymerase sliding clamp
total genus 62
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2003-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1rxmA00
1RXMA 2OD8A 5JNED 1CZDA 3AIZA 1YYPA 1B77A 2NTIA 3A2FB 1UL1A 1IZ5A 5B7OA 5IWDA 3G65A 1RWZA 2IX2A 5E0UA 2NTIB 3GGRA 5IY4A 2IZOB 5DA7A 3TBLA 1U7BA 5IXAA 3FDSD 3U5ZF 2IO4A 2HIIB 4RJFA 3I2MX 2Z0LA 3LX2A 3GPNA 3HSLX 2HIKA 3AIXB 2NTIC 1RXZA 3P87A 2IZOC 3U60F 2ZVKA 3A1JA 3P83A 2AVTA 5AUJA 1VYJA 4L60A 1SXJF 2HIIC 3V61B 3IFVA 1B8HA 1PLQA 1VYMA 1UD9A 3FDSC 3G65B 5DAIA 1IZ4A 3U61F 2IX2B 1U76A 2ZVWA 3GGRB 3AIZC 3P91A 3V62B 4CS5A 2ZVLA 2IO4B 3HI8A 3A1JC 4ZTDA 1PLRA 4TR6A 3G65C 2IX2C 2HIKB 2ZVVA 3WGWA 4HK1A 3GGRC 3A1JB 5E0TA 4L6PA 5A6DA 1AXCA 3VKXA 5H0TA 1DMLA 3K4XA 1T6LA 1GE8A 3GPMA 4D2GA 2ZVMA 1W60A 2HIKC 1ISQA 3F1WA 2HIIA 3V60B 2AWAA 5E0VA 3LX1A 2IJXA 3AIXA 5HACA 4YHRA 5CFKA
chains in the Genus database with same CATH superfamily
1RXMA 2OD8A 5JNED 1CZDA 3AIZA 1YYPA 1B77A 2NTIA 3A2FB 1UL1A 1IZ5A 5B7OA 5IWDA 3G65A 1RWZA 2IX2A 5E0UA 2NTIB 3GGRA 5IY4A 2IZOB 5DA7A 3TBLA 1U7BA 5IXAA 3FDSD 3U5ZF 2IO4A 2HIIB 4RJFA 3I2MX 2Z0LA 3LX2A 3GPNA 3HSLX 2HIKA 3AIXB 2NTIC 1RXZA 3P87A 2IZOC 3U60F 2ZVKA 3A1JA 3P83A 2AVTA 5AUJA 1VYJA 4L60A 1SXJF 2HIIC 3V61B 3IFVA 1B8HA 1PLQA 1VYMA 1UD9A 3FDSC 3G65B 5DAIA 1IZ4A 3U61F 2IX2B 1U76A 2ZVWA 3GGRB 3AIZC 3P91A 3V62B 4CS5A 2ZVLA 2IO4B 3HI8A 3A1JC 4ZTDA 1PLRA 4TR6A 3G65C 2IX2C 2HIKB 2ZVVA 3WGWA 4HK1A 3GGRC 3A1JB 5E0TA 4L6PA 5A6DA 1AXCA 3VKXA 5H0TA 1DMLA 3K4XA 1T6LA 1GE8A 3GPMA 4D2GA 2ZVMA 1W60A 2HIKC 1ISQA 3F1WA 2HIIA 3V60B 2AWAA 5E0VA 3LX1A 2IJXA 3AIXA 5HACA 4YHRA 5CFKA
chains in the Genus database with same CATH topology
1RXMA 2OD8A 5JNED 1CZDA 3AIZA 1YYPA 1B77A 2NTIA 3A2FB 1UL1A 1IZ5A 5B7OA 5IWDA 3G65A 1RWZA 2IX2A 5E0UA 2NTIB 3GGRA 5IY4A 2IZOB 5DA7A 3TBLA 1U7BA 5IXAA 3FDSD 3U5ZF 2IO4A 2HIIB 4RJFA 3I2MX 2Z0LA 3LX2A 3GPNA 3HSLX 2HIKA 3AIXB 2NTIC 1RXZA 3P87A 2IZOC 3U60F 2ZVKA 3A1JA 3P83A 2AVTA 5AUJA 1VYJA 4L60A 1SXJF 2HIIC 3V61B 3IFVA 1B8HA 1PLQA 1VYMA 1UD9A 3FDSC 3G65B 5DAIA 1IZ4A 3U61F 2IX2B 1U76A 2ZVWA 3GGRB 3AIZC 3P91A 3V62B 4CS5A 2ZVLA 2IO4B 3HI8A 3A1JC 4ZTDA 1PLRA 4TR6A 3G65C 2IX2C 2HIKB 2ZVVA 3WGWA 4HK1A 3GGRC 3A1JB 5E0TA 4L6PA 5A6DA 1AXCA 3VKXA 5H0TA 1DMLA 3K4XA 1T6LA 1GE8A 3GPMA 4D2GA 2ZVMA 1W60A 2HIKC 1ISQA 3F1WA 2HIIA 3V60B 2AWAA 5E0VA 3LX1A 2IJXA 3AIXA 5HACA 4YHRA 5CFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RXM A;  2OD8 A;  5JNE D;  1CZD A;  3AIZ A;  1YYP A;  1B77 A;  2NTI A;  3A2F B;  1UL1 A;  1IZ5 A;  5B7O A;  5IWD A;  3G65 A;  1RWZ A;  2IX2 A;  5E0U A;  2NTI B;  3GGR A;  5IY4 A;  2IZO B;  5DA7 A;  3TBL A;  1U7B A;  5IXA A;  3FDS D;  3U5Z F;  2IO4 A;  2HII B;  4RJF A;  3I2M X;  2Z0L A;  3LX2 A;  3GPN A;  3HSL X;  2HIK A;  3AIX B;  2NTI C;  1RXZ A;  3P87 A;  2IZO C;  3U60 F;  2ZVK A;  3A1J A;  3P83 A;  2AVT A;  5AUJ A;  1VYJ A;  4L60 A;  1SXJ F;  2HII C;  3V61 B;  3IFV A;  1B8H A;  1PLQ A;  1VYM A;  1UD9 A;  3FDS C;  3G65 B;  5DAI A;  1IZ4 A;  3U61 F;  2IX2 B;  1U76 A;  2ZVW A;  3GGR B;  3AIZ C;  3P91 A;  3V62 B;  4CS5 A;  2ZVL A;  2IO4 B;  3HI8 A;  3A1J C;  4ZTD A;  1PLR A;  4TR6 A;  3G65 C;  2IX2 C;  2HIK B;  2ZVV A;  3WGW A;  4HK1 A;  3GGR C;  3A1J B;  5E0T A;  4L6P A;  5A6D A;  1AXC A;  3VKX A;  5H0T A;  1DML A;  3K4X A;  1T6L A;  1GE8 A;  3GPM A;  4D2G A;  2ZVM A;  1W60 A;  2HIK C;  1ISQ A;  3F1W A;  2HII A;  3V60 B;  2AWA A;  5E0V A;  3LX1 A;  2IJX A;  3AIX A;  5HAC A;  4YHR A;  5CFK A; 
#chains in the Genus database with same CATH topology
 1RXM A;  2OD8 A;  5JNE D;  1CZD A;  3AIZ A;  1YYP A;  1B77 A;  2NTI A;  3A2F B;  1UL1 A;  1IZ5 A;  5B7O A;  5IWD A;  3G65 A;  1RWZ A;  2IX2 A;  5E0U A;  2NTI B;  3GGR A;  5IY4 A;  2IZO B;  5DA7 A;  3TBL A;  1U7B A;  5IXA A;  3FDS D;  3U5Z F;  2IO4 A;  2HII B;  4RJF A;  3I2M X;  2Z0L A;  3LX2 A;  3GPN A;  3HSL X;  2HIK A;  3AIX B;  2NTI C;  1RXZ A;  3P87 A;  2IZO C;  3U60 F;  2ZVK A;  3A1J A;  3P83 A;  2AVT A;  5AUJ A;  1VYJ A;  4L60 A;  1SXJ F;  2HII C;  3V61 B;  3IFV A;  1B8H A;  1PLQ A;  1VYM A;  1UD9 A;  3FDS C;  3G65 B;  5DAI A;  1IZ4 A;  3U61 F;  2IX2 B;  1U76 A;  2ZVW A;  3GGR B;  3AIZ C;  3P91 A;  3V62 B;  4CS5 A;  2ZVL A;  2IO4 B;  3HI8 A;  3A1J C;  4ZTD A;  1PLR A;  4TR6 A;  3G65 C;  2IX2 C;  2HIK B;  2ZVV A;  3WGW A;  4HK1 A;  3GGR C;  3A1J B;  5E0T A;  4L6P A;  5A6D A;  1AXC A;  3VKX A;  5H0T A;  1DML A;  3K4X A;  1T6L A;  1GE8 A;  3GPM A;  4D2G A;  2ZVM A;  1W60 A;  2HIK C;  1ISQ A;  3F1W A;  2HII A;  3V60 B;  2AWA A;  5E0V A;  3LX1 A;  2IJX A;  3AIX A;  5HAC A;  4YHR A;  5CFK A; 
#chains in the Genus database with same CATH homology
 1RXM A;  2OD8 A;  5JNE D;  1CZD A;  3AIZ A;  1YYP A;  1B77 A;  2NTI A;  3A2F B;  1UL1 A;  1IZ5 A;  5B7O A;  5IWD A;  3G65 A;  1RWZ A;  2IX2 A;  5E0U A;  2NTI B;  3GGR A;  5IY4 A;  2IZO B;  5DA7 A;  3TBL A;  1U7B A;  5IXA A;  3FDS D;  3U5Z F;  2IO4 A;  2HII B;  4RJF A;  3I2M X;  2Z0L A;  3LX2 A;  3GPN A;  3HSL X;  2HIK A;  3AIX B;  2NTI C;  1RXZ A;  3P87 A;  2IZO C;  3U60 F;  2ZVK A;  3A1J A;  3P83 A;  2AVT A;  5AUJ A;  1VYJ A;  4L60 A;  1SXJ F;  2HII C;  3V61 B;  3IFV A;  1B8H A;  1PLQ A;  1VYM A;  1UD9 A;  3FDS C;  3G65 B;  5DAI A;  1IZ4 A;  3U61 F;  2IX2 B;  1U76 A;  2ZVW A;  3GGR B;  3AIZ C;  3P91 A;  3V62 B;  4CS5 A;  2ZVL A;  2IO4 B;  3HI8 A;  3A1J C;  4ZTD A;  1PLR A;  4TR6 A;  3G65 C;  2IX2 C;  2HIK B;  2ZVV A;  3WGW A;  4HK1 A;  3GGR C;  3A1J B;  5E0T A;  4L6P A;  5A6D A;  1AXC A;  3VKX A;  5H0T A;  1DML A;  3K4X A;  1T6L A;  1GE8 A;  3GPM A;  4D2G A;  2ZVM A;  1W60 A;  2HIK C;  1ISQ A;  3F1W A;  2HII A;  3V60 B;  2AWA A;  5E0V A;  3LX1 A;  2IJX A;  3AIX A;  5HAC A;  4YHR A;  5CFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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