1SI3A

Crystal structure of the paz domain of human eif2c1 in complex with a 9-mer sirna-like duplex
Total Genus 26
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
126
structure length
120
Chain Sequence
MAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
pubmed doi rcsb
molecule tags Gene regulation/rna
source organism Homo sapiens
molecule keywords 5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3'
total genus 26
structure length 120
sequence length 126
ec nomenclature
pdb deposition date 2004-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1si3A00
2FFLA 1SI3A 4Z4GA 3O6EX 4F3TA 1SI2A 4NH3A 2QVWA 5T7BA 4KREA 1VYNA 1R6ZA 4NH6A 4W5OA 1R4KA 4W5RA 2L5CA 2XFMA 3O7XA 5JS1A 4Z4FA 4Z4HA 4NH5A 3QIRA 4NGGA 4W5NA 2L5DA 4Z4CA 3MJ0A 4NHAA 4OLBA 4KRFA 3O7VX 4NGDA 4W5QA 1T2RA 4OLAA 4NGFA 4W5TA 1T2SA 5JS2A 5KI6A 4NGBA 4NGCA 4Z4EA 4Z4IA 3O3IX
chains in the Genus database with same CATH superfamily
2DB9A 2FFLA 1SI3A 4Z4GA 3O6EX 4NGCA 4F3TA 1SI2A 4NH3A 2QVWA 5T7BA 4KREA 1VYNA 1R6ZA 4NH6A 4W5OA 1R4KA 4W5RA 2L5CA 2XFMA 3O7XA 5JS1A 3HM9A 4Z4FA 3HVRA 2BZEA 3HK2A 4L1PA 4Z4HA 4NH5A 3QIRA 4NGGA 3DA5A 3F73A 4W5NA 3DLHA 3HO1A 2L5DA 4Z4CA 1U04A 3DLBA 3MJ0A 4NHAA 3HJFA 4OLBA 4KRFA 3O7VX 4NGDA 4W5QA 3U1UA 1T2RA 4OLAA 4NGFA 4W5TA 1Z25A 4L1UA 1T2SA 5JS2A 5KI6A 4NGBA 1Z26A 4Z4EA 4Z4IA 3O3IX
chains in the Genus database with same CATH topology
2DB9A 2FFLA 1SI3A 4Z4GA 3O6EX 4NGCA 4F3TA 1SI2A 4NH3A 2QVWA 5T7BA 4KREA 1VYNA 1R6ZA 4NH6A 4W5OA 1R4KA 4W5RA 2L5CA 2XFMA 3O7XA 5JS1A 3HM9A 4Z4FA 3HVRA 2BZEA 3HK2A 4L1PA 4Z4HA 4NH5A 3QIRA 4NGGA 3DA5A 3F73A 4W5NA 3DLHA 3HO1A 2L5DA 4Z4CA 1U04A 3DLBA 3MJ0A 4NHAA 3HJFA 4OLBA 4KRFA 3O7VX 4NGDA 4W5QA 3U1UA 1T2RA 4OLAA 4NGFA 4W5TA 1Z25A 4L1UA 1T2SA 5JS2A 5KI6A 4NGBA 1Z26A 4Z4EA 4Z4IA 3O3IX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FFL A;  1SI3 A;  4Z4G A;  3O6E X;  4F3T A;  1SI2 A;  4NH3 A;  2QVW A;  5T7B A;  4KRE A;  1VYN A;  1R6Z A;  4NH6 A;  4W5O A;  1R4K A;  4W5R A;  2L5C A;  2XFM A;  3O7X A;  5JS1 A;  4Z4F A;  4Z4H A;  4NH5 A;  3QIR A;  4NGG A;  4W5N A;  2L5D A;  4Z4C A;  3MJ0 A;  4NHA A;  4OLB A;  4KRF A;  3O7V X;  4NGD A;  4W5Q A;  1T2R A;  4OLA A;  4NGF A;  4W5T A;  1T2S A;  5JS2 A;  5KI6 A;  4NGB A;  4NGC A;  4Z4E A;  4Z4I A;  3O3I X; 
#chains in the Genus database with same CATH topology
 2DB9 A;  2FFL A;  1SI3 A;  4Z4G A;  3O6E X;  4NGC A;  4F3T A;  1SI2 A;  4NH3 A;  2QVW A;  5T7B A;  4KRE A;  1VYN A;  1R6Z A;  4NH6 A;  4W5O A;  1R4K A;  4W5R A;  2L5C A;  2XFM A;  3O7X A;  5JS1 A;  3HM9 A;  4Z4F A;  3HVR A;  2BZE A;  3HK2 A;  4L1P A;  4Z4H A;  4NH5 A;  3QIR A;  4NGG A;  3DA5 A;  3F73 A;  4W5N A;  3DLH A;  3HO1 A;  2L5D A;  4Z4C A;  1U04 A;  3DLB A;  3MJ0 A;  4NHA A;  3HJF A;  4OLB A;  4KRF A;  3O7V X;  4NGD A;  4W5Q A;  3U1U A;  1T2R A;  4OLA A;  4NGF A;  4W5T A;  1Z25 A;  4L1U A;  1T2S A;  5JS2 A;  5KI6 A;  4NGB A;  1Z26 A;  4Z4E A;  4Z4I A;  3O3I X; 
#chains in the Genus database with same CATH homology
 2DB9 A;  2FFL A;  1SI3 A;  4Z4G A;  3O6E X;  4NGC A;  4F3T A;  1SI2 A;  4NH3 A;  2QVW A;  5T7B A;  4KRE A;  1VYN A;  1R6Z A;  4NH6 A;  4W5O A;  1R4K A;  4W5R A;  2L5C A;  2XFM A;  3O7X A;  5JS1 A;  3HM9 A;  4Z4F A;  3HVR A;  2BZE A;  3HK2 A;  4L1P A;  4Z4H A;  4NH5 A;  3QIR A;  4NGG A;  3DA5 A;  3F73 A;  4W5N A;  3DLH A;  3HO1 A;  2L5D A;  4Z4C A;  1U04 A;  3DLB A;  3MJ0 A;  4NHA A;  3HJF A;  4OLB A;  4KRF A;  3O7V X;  4NGD A;  4W5Q A;  3U1U A;  1T2R A;  4OLA A;  4NGF A;  4W5T A;  1Z25 A;  4L1U A;  1T2S A;  5JS2 A;  5KI6 A;  4NGB A;  1Z26 A;  4Z4E A;  4Z4I A;  3O3I X; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...