1T2RA

Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
123
structure length
123
Chain Sequence
GAMAMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
pubmed doi rcsb
molecule tags Nucleic acid binding protein/rna
source organism Drosophila melanogaster
molecule keywords 5'-R(*CP*UP*CP*AP*C)-3'
total genus 26
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2004-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1t2rA00
3O6EX 3O7VX 5KI6A 3O3IX 4W5QA 4OLBA 1SI3A 4F3TA 4W5RA 1VYNA 4W5NA 1SI2A 4W5OA 4NGFA 4NGDA 4NH3A 4NGGA 1T2SA 4Z4EA 3QIRA 4NH5A 1R6ZA 5T7BA 2FFLA 4KRFA 4W5TA 1T2RA 4Z4CA 2L5DA 4KREA 4Z4GA 3MJ0A 5JS2A 4NGBA 2XFMA 4NGCA 4Z4HA 2L5CA 4NH6A 5JS1A 3O7XA 4Z4FA 2QVWA 4Z4IA 4NHAA 1R4KA 4OLAA
chains in the Genus database with same CATH superfamily
3O6EX 1U04A 5KI6A 3O3IX 1Z26A 4W5QA 3O7VX 4OLBA 3HJFA 1SI3A 4L1PA 4F3TA 4W5RA 1VYNA 1R4KA 1SI2A 4W5OA 4NGFA 4W5NA 4NGDA 4NH3A 4NGGA 1T2SA 4Z4EA 3QIRA 3U1UA 4NH5A 3HVRA 1Z25A 1R6ZA 5T7BA 2FFLA 3HO1A 4KRFA 3F73A 4W5TA 1T2RA 4Z4CA 3DA5A 2L5DA 3HK2A 4KREA 4Z4GA 3MJ0A 5JS2A 2BZEA 3HM9A 4NGBA 2XFMA 4NGCA 4Z4HA 2L5CA 3DLBA 4NH6A 3DLHA 5JS1A 2DB9A 3O7XA 4Z4FA 2QVWA 4Z4IA 4NHAA 4L1UA 4OLAA
chains in the Genus database with same CATH topology
3O6EX 1U04A 5KI6A 3O3IX 1Z26A 4W5QA 3O7VX 4OLBA 3HJFA 1SI3A 4L1PA 4F3TA 4W5RA 1VYNA 1R4KA 1SI2A 4W5OA 4NGFA 4W5NA 4NGDA 4NH3A 4NGGA 1T2SA 4Z4EA 3QIRA 3U1UA 4NH5A 3HVRA 1Z25A 1R6ZA 5T7BA 2FFLA 3HO1A 4KRFA 3F73A 4W5TA 1T2RA 4Z4CA 3DA5A 2L5DA 3HK2A 4KREA 4Z4GA 3MJ0A 5JS2A 2BZEA 3HM9A 4NGBA 2XFMA 4NGCA 4Z4HA 2L5CA 3DLBA 4NH6A 3DLHA 5JS1A 2DB9A 3O7XA 4Z4FA 2QVWA 4Z4IA 4NHAA 4L1UA 4OLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O6E X;  3O7V X;  5KI6 A;  3O3I X;  4W5Q A;  4OLB A;  1SI3 A;  4F3T A;  4W5R A;  1VYN A;  4W5N A;  1SI2 A;  4W5O A;  4NGF A;  4NGD A;  4NH3 A;  4NGG A;  1T2S A;  4Z4E A;  3QIR A;  4NH5 A;  1R6Z A;  5T7B A;  2FFL A;  4KRF A;  4W5T A;  1T2R A;  4Z4C A;  2L5D A;  4KRE A;  4Z4G A;  3MJ0 A;  5JS2 A;  4NGB A;  2XFM A;  4NGC A;  4Z4H A;  2L5C A;  4NH6 A;  5JS1 A;  3O7X A;  4Z4F A;  2QVW A;  4Z4I A;  4NHA A;  1R4K A;  4OLA A; 
#chains in the Genus database with same CATH topology
 3O6E X;  1U04 A;  5KI6 A;  3O3I X;  1Z26 A;  4W5Q A;  3O7V X;  4OLB A;  3HJF A;  1SI3 A;  4L1P A;  4F3T A;  4W5R A;  1VYN A;  1R4K A;  1SI2 A;  4W5O A;  4NGF A;  4W5N A;  4NGD A;  4NH3 A;  4NGG A;  1T2S A;  4Z4E A;  3QIR A;  3U1U A;  4NH5 A;  3HVR A;  1Z25 A;  1R6Z A;  5T7B A;  2FFL A;  3HO1 A;  4KRF A;  3F73 A;  4W5T A;  1T2R A;  4Z4C A;  3DA5 A;  2L5D A;  3HK2 A;  4KRE A;  4Z4G A;  3MJ0 A;  5JS2 A;  2BZE A;  3HM9 A;  4NGB A;  2XFM A;  4NGC A;  4Z4H A;  2L5C A;  3DLB A;  4NH6 A;  3DLH A;  5JS1 A;  2DB9 A;  3O7X A;  4Z4F A;  2QVW A;  4Z4I A;  4NHA A;  4L1U A;  4OLA A; 
#chains in the Genus database with same CATH homology
 3O6E X;  1U04 A;  5KI6 A;  3O3I X;  1Z26 A;  4W5Q A;  3O7V X;  4OLB A;  3HJF A;  1SI3 A;  4L1P A;  4F3T A;  4W5R A;  1VYN A;  1R4K A;  1SI2 A;  4W5O A;  4NGF A;  4W5N A;  4NGD A;  4NH3 A;  4NGG A;  1T2S A;  4Z4E A;  3QIR A;  3U1U A;  4NH5 A;  3HVR A;  1Z25 A;  1R6Z A;  5T7B A;  2FFL A;  3HO1 A;  4KRF A;  3F73 A;  4W5T A;  1T2R A;  4Z4C A;  3DA5 A;  2L5D A;  3HK2 A;  4KRE A;  4Z4G A;  3MJ0 A;  5JS2 A;  2BZE A;  3HM9 A;  4NGB A;  2XFM A;  4NGC A;  4Z4H A;  2L5C A;  3DLB A;  4NH6 A;  3DLH A;  5JS1 A;  2DB9 A;  3O7X A;  4Z4F A;  2QVW A;  4Z4I A;  4NHA A;  4L1U A;  4OLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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