1T2SA

Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
123
structure length
123
Chain Sequence
GAMAMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Nucleic acid binding protein/dna
source organism Drosophila melanogaster
publication title Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
pubmed doi rcsb
molecule keywords 5'-D(*CP*TP*CP*AP*C)-3'
total genus 22
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2004-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1t2sA00
4NGBA 4Z4HA 5T7BA 5JS1A 4W5RA 1T2SA 3O7XA 4KREA 2XFMA 5KI6A 1VYNA 4Z4CA 3QIRA 3O3IX 1R6ZA 4W5OA 1T2RA 4NGCA 2L5DA 4NH5A 2L5CA 3O7VX 4Z4IA 4Z4GA 3MJ0A 4Z4EA 2FFLA 3O6EX 1SI3A 1R4KA 4OLBA 4NH3A 4NGGA 4W5TA 4Z4FA 4W5QA 4NHAA 4W5NA 4NH6A 4OLAA 4F3TA 1SI2A 2QVWA 4NGFA 4KRFA 4NGDA 5JS2A
chains in the Genus database with same CATH superfamily
3DLHA 4NGBA 4Z4HA 5T7BA 5JS1A 2DB9A 4W5RA 1T2SA 1Z25A 3O7XA 3HM9A 3F73A 4KREA 1U04A 2XFMA 5KI6A 1VYNA 4Z4CA 3QIRA 3O3IX 1R6ZA 4W5OA 1T2RA 4NGCA 2L5DA 3HO1A 2L5CA 4NH5A 3O7VX 4Z4IA 4Z4GA 3MJ0A 3DLBA 4Z4EA 3HVRA 2BZEA 2FFLA 4L1PA 3O6EX 1R4KA 4OLBA 1SI3A 4NH3A 4NGGA 4L1UA 4W5TA 3HJFA 4Z4FA 4W5QA 4NHAA 4W5NA 4NH6A 3U1UA 4OLAA 4F3TA 1SI2A 1Z26A 2QVWA 3HK2A 4NGFA 3DA5A 4NGDA 4KRFA 5JS2A
chains in the Genus database with same CATH topology
3DLHA 4NGBA 4Z4HA 5T7BA 5JS1A 2DB9A 4W5RA 1T2SA 1Z25A 3O7XA 3HM9A 3F73A 4KREA 1U04A 2XFMA 5KI6A 1VYNA 4Z4CA 3QIRA 3O3IX 1R6ZA 4W5OA 1T2RA 4NGCA 2L5DA 3HO1A 2L5CA 4NH5A 3O7VX 4Z4IA 4Z4GA 3MJ0A 3DLBA 4Z4EA 3HVRA 2BZEA 2FFLA 4L1PA 3O6EX 1R4KA 4OLBA 1SI3A 4NH3A 4NGGA 4L1UA 4W5TA 3HJFA 4Z4FA 4W5QA 4NHAA 4W5NA 4NH6A 3U1UA 4OLAA 4F3TA 1SI2A 1Z26A 2QVWA 3HK2A 4NGFA 3DA5A 4NGDA 4KRFA 5JS2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NGB A;  4Z4H A;  5T7B A;  5JS1 A;  4W5R A;  1T2S A;  3O7X A;  4KRE A;  2XFM A;  5KI6 A;  1VYN A;  4Z4C A;  3QIR A;  3O3I X;  1R6Z A;  4W5O A;  1T2R A;  4NGC A;  2L5D A;  4NH5 A;  2L5C A;  3O7V X;  4Z4I A;  4Z4G A;  3MJ0 A;  4Z4E A;  2FFL A;  3O6E X;  1SI3 A;  1R4K A;  4OLB A;  4NH3 A;  4NGG A;  4W5T A;  4Z4F A;  4W5Q A;  4NHA A;  4W5N A;  4NH6 A;  4OLA A;  4F3T A;  1SI2 A;  2QVW A;  4NGF A;  4KRF A;  4NGD A;  5JS2 A; 
#chains in the Genus database with same CATH topology
 3DLH A;  4NGB A;  4Z4H A;  5T7B A;  5JS1 A;  2DB9 A;  4W5R A;  1T2S A;  1Z25 A;  3O7X A;  3HM9 A;  3F73 A;  4KRE A;  1U04 A;  2XFM A;  5KI6 A;  1VYN A;  4Z4C A;  3QIR A;  3O3I X;  1R6Z A;  4W5O A;  1T2R A;  4NGC A;  2L5D A;  3HO1 A;  2L5C A;  4NH5 A;  3O7V X;  4Z4I A;  4Z4G A;  3MJ0 A;  3DLB A;  4Z4E A;  3HVR A;  2BZE A;  2FFL A;  4L1P A;  3O6E X;  1R4K A;  4OLB A;  1SI3 A;  4NH3 A;  4NGG A;  4L1U A;  4W5T A;  3HJF A;  4Z4F A;  4W5Q A;  4NHA A;  4W5N A;  4NH6 A;  3U1U A;  4OLA A;  4F3T A;  1SI2 A;  1Z26 A;  2QVW A;  3HK2 A;  4NGF A;  3DA5 A;  4NGD A;  4KRF A;  5JS2 A; 
#chains in the Genus database with same CATH homology
 3DLH A;  4NGB A;  4Z4H A;  5T7B A;  5JS1 A;  2DB9 A;  4W5R A;  1T2S A;  1Z25 A;  3O7X A;  3HM9 A;  3F73 A;  4KRE A;  1U04 A;  2XFM A;  5KI6 A;  1VYN A;  4Z4C A;  3QIR A;  3O3I X;  1R6Z A;  4W5O A;  1T2R A;  4NGC A;  2L5D A;  3HO1 A;  2L5C A;  4NH5 A;  3O7V X;  4Z4I A;  4Z4G A;  3MJ0 A;  3DLB A;  4Z4E A;  3HVR A;  2BZE A;  2FFL A;  4L1P A;  3O6E X;  1R4K A;  4OLB A;  1SI3 A;  4NH3 A;  4NGG A;  4L1U A;  4W5T A;  3HJF A;  4Z4F A;  4W5Q A;  4NHA A;  4W5N A;  4NH6 A;  3U1U A;  4OLA A;  4F3T A;  1SI2 A;  1Z26 A;  2QVW A;  3HK2 A;  4NGF A;  3DA5 A;  4NGD A;  4KRF A;  5JS2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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