1T2SA

Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
123
structure length
123
Chain Sequence
GAMAMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
pubmed doi rcsb
molecule tags Nucleic acid binding protein/dna
source organism Drosophila melanogaster
molecule keywords 5'-D(*CP*TP*CP*AP*C)-3'
total genus 22
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2004-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1t2sA00
4OLBA 4NH3A 1R4KA 2QVWA 4NGGA 2L5CA 3O6EX 4NGFA 4Z4IA 4W5OA 5JS1A 2XFMA 4NH6A 3QIRA 1VYNA 4NGCA 4W5TA 1SI2A 4NGDA 5JS2A 4Z4EA 4Z4FA 3O7XA 1SI3A 4Z4GA 4OLAA 5KI6A 5T7BA 3MJ0A 4KRFA 4W5QA 3O7VX 1T2SA 4NGBA 4Z4HA 1R6ZA 4F3TA 4KREA 2L5DA 4W5NA 2FFLA 4NH5A 3O3IX 4Z4CA 4W5RA 1T2RA 4NHAA
chains in the Genus database with same CATH superfamily
4OLBA 4NH3A 4W5NA 1R4KA 2QVWA 4NGGA 2L5CA 3O6EX 4NGFA 4Z4IA 3HM9A 4W5OA 3DLBA 5JS1A 4L1PA 2XFMA 1Z25A 4NH6A 3QIRA 3F73A 3HJFA 1VYNA 4NGCA 3DA5A 4W5TA 1SI2A 4NGDA 5JS2A 4Z4EA 4Z4FA 3O7XA 3U1UA 2BZEA 4Z4GA 1SI3A 4OLAA 5KI6A 5T7BA 4L1UA 3MJ0A 4KRFA 4W5QA 3O7VX 1T2SA 3DLHA 1R6ZA 4Z4HA 4NGBA 4F3TA 2L5DA 4KREA 2FFLA 4NH5A 3O3IX 1U04A 4Z4CA 4W5RA 2DB9A 3HVRA 3HO1A 3HK2A 1T2RA 1Z26A 4NHAA
chains in the Genus database with same CATH topology
4OLBA 4NH3A 4W5NA 1R4KA 2QVWA 4NGGA 2L5CA 3O6EX 4NGFA 4Z4IA 3HM9A 4W5OA 3DLBA 5JS1A 4L1PA 2XFMA 1Z25A 4NH6A 3QIRA 3F73A 3HJFA 1VYNA 4NGCA 3DA5A 4W5TA 1SI2A 4NGDA 5JS2A 4Z4EA 4Z4FA 3O7XA 3U1UA 2BZEA 4Z4GA 1SI3A 4OLAA 5KI6A 5T7BA 4L1UA 3MJ0A 4KRFA 4W5QA 3O7VX 1T2SA 3DLHA 1R6ZA 4Z4HA 4NGBA 4F3TA 2L5DA 4KREA 2FFLA 4NH5A 3O3IX 1U04A 4Z4CA 4W5RA 2DB9A 3HVRA 3HO1A 3HK2A 1T2RA 1Z26A 4NHAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OLB A;  4NH3 A;  1R4K A;  2QVW A;  4NGG A;  2L5C A;  3O6E X;  4NGF A;  4Z4I A;  4W5O A;  5JS1 A;  2XFM A;  4NH6 A;  3QIR A;  1VYN A;  4NGC A;  4W5T A;  1SI2 A;  4NGD A;  5JS2 A;  4Z4E A;  4Z4F A;  3O7X A;  1SI3 A;  4Z4G A;  4OLA A;  5KI6 A;  5T7B A;  3MJ0 A;  4KRF A;  4W5Q A;  3O7V X;  1T2S A;  4NGB A;  4Z4H A;  1R6Z A;  4F3T A;  4KRE A;  2L5D A;  4W5N A;  2FFL A;  4NH5 A;  3O3I X;  4Z4C A;  4W5R A;  1T2R A;  4NHA A; 
#chains in the Genus database with same CATH topology
 4OLB A;  4NH3 A;  4W5N A;  1R4K A;  2QVW A;  4NGG A;  2L5C A;  3O6E X;  4NGF A;  4Z4I A;  3HM9 A;  4W5O A;  3DLB A;  5JS1 A;  4L1P A;  2XFM A;  1Z25 A;  4NH6 A;  3QIR A;  3F73 A;  3HJF A;  1VYN A;  4NGC A;  3DA5 A;  4W5T A;  1SI2 A;  4NGD A;  5JS2 A;  4Z4E A;  4Z4F A;  3O7X A;  3U1U A;  2BZE A;  4Z4G A;  1SI3 A;  4OLA A;  5KI6 A;  5T7B A;  4L1U A;  3MJ0 A;  4KRF A;  4W5Q A;  3O7V X;  1T2S A;  3DLH A;  1R6Z A;  4Z4H A;  4NGB A;  4F3T A;  2L5D A;  4KRE A;  2FFL A;  4NH5 A;  3O3I X;  1U04 A;  4Z4C A;  4W5R A;  2DB9 A;  3HVR A;  3HO1 A;  3HK2 A;  1T2R A;  1Z26 A;  4NHA A; 
#chains in the Genus database with same CATH homology
 4OLB A;  4NH3 A;  4W5N A;  1R4K A;  2QVW A;  4NGG A;  2L5C A;  3O6E X;  4NGF A;  4Z4I A;  3HM9 A;  4W5O A;  3DLB A;  5JS1 A;  4L1P A;  2XFM A;  1Z25 A;  4NH6 A;  3QIR A;  3F73 A;  3HJF A;  1VYN A;  4NGC A;  3DA5 A;  4W5T A;  1SI2 A;  4NGD A;  5JS2 A;  4Z4E A;  4Z4F A;  3O7X A;  3U1U A;  2BZE A;  4Z4G A;  1SI3 A;  4OLA A;  5KI6 A;  5T7B A;  4L1U A;  3MJ0 A;  4KRF A;  4W5Q A;  3O7V X;  1T2S A;  3DLH A;  1R6Z A;  4Z4H A;  4NGB A;  4F3T A;  2L5D A;  4KRE A;  2FFL A;  4NH5 A;  3O3I X;  1U04 A;  4Z4C A;  4W5R A;  2DB9 A;  3HVR A;  3HO1 A;  3HK2 A;  1T2R A;  1Z26 A;  4NHA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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