1ISQA

Pyrococcus furiosus pcna complexed with rfcl pip-box peptide
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
246
structure length
240
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEPELPFTAKVVVLGEVLKDAVKDASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
pubmed doi rcsb
molecule tags Dna binding protein
source organism Pyrococcus furiosus
molecule keywords Proliferating Cell Nuclear Antigen
total genus 59
structure length 240
sequence length 246
ec nomenclature
pdb deposition date 2001-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1isqA00
2IX2C 3P83A 4TR6A 3U61F 1PLRA 4HK1A 2HIIC 3P87A 3A1JC 3GPMA 5H0TA 1AXCA 4CS5A 2NTIB 3A2FB 3AIZA 2IJXA 3G65B 3TBLA 1SXJF 2HIKA 5IY4A 2ZVKA 5IWDA 3GGRA 3LX1A 2IZOB 3WGWA 2ZVWA 3AIXA 3P91A 3AIZC 1IZ5A 2ZVLA 1VYMA 3VKXA 5E0VA 2HIKC 1YYPA 1ISQA 5E0TA 5B7OA 5DA7A 1B8HA 1W60A 3GGRC 3HI8A 2ZVVA 1DMLA 4L6PA 2NTIA 3G65A 1RXMA 1UD9A 3V62B 2AVTA 5IXAA 3U60F 1PLQA 3LX2A 2NTIC 3G65C 2IX2B 3FDSC 4RJFA 3HSLX 2AWAA 3GPNA 2HIIB 3A1JB 3GGRB 1GE8A 3IFVA 4D2GA 2IO4B 1RWZA 1CZDA 2IZOC 5DAIA 1VYJA 1U76A 4L60A 2ZVMA 5AUJA 3F1WA 1RXZA 3V60B 5CFKA 5HACA 2OD8A 1T6LA 3U5ZF 5JNED 1U7BA 1B77A 2Z0LA 1IZ4A 2IX2A 3FDSD 2HIKB 1UL1A 4YHRA 3K4XA 2HIIA 3A1JA 3V61B 5E0UA 2IO4A 4ZTDA 5A6DA 3I2MX 3AIXB
chains in the Genus database with same CATH superfamily
2IX2C 3P83A 4TR6A 3U61F 1PLRA 4HK1A 2HIIC 3P87A 3A1JC 3GPMA 5H0TA 1AXCA 4CS5A 2NTIB 3A2FB 3AIZA 2IJXA 3G65B 3TBLA 1SXJF 2HIKA 5IY4A 2ZVKA 5IWDA 3GGRA 3LX1A 2IZOB 3WGWA 2ZVWA 3AIXA 3P91A 3AIZC 1IZ5A 2ZVLA 1VYMA 3VKXA 5E0VA 2HIKC 1YYPA 1ISQA 5E0TA 5B7OA 5DA7A 1B8HA 1W60A 3GGRC 3HI8A 2ZVVA 1DMLA 4L6PA 2NTIA 3G65A 1RXMA 1UD9A 3V62B 2AVTA 5IXAA 3U60F 1PLQA 3LX2A 2NTIC 3G65C 2IX2B 3FDSC 4RJFA 3HSLX 2AWAA 3GPNA 2HIIB 3A1JB 3GGRB 1GE8A 3IFVA 4D2GA 2IO4B 1RWZA 1CZDA 2IZOC 5DAIA 1VYJA 1U76A 4L60A 2ZVMA 5AUJA 3F1WA 1RXZA 3V60B 5CFKA 5HACA 2OD8A 1T6LA 3U5ZF 5JNED 1U7BA 1B77A 2Z0LA 1IZ4A 2IX2A 3FDSD 2HIKB 1UL1A 4YHRA 3K4XA 2HIIA 3A1JA 3V61B 5E0UA 2IO4A 4ZTDA 5A6DA 3I2MX 3AIXB
chains in the Genus database with same CATH topology
2IX2C 3P83A 4TR6A 3U61F 1PLRA 4HK1A 2HIIC 3P87A 3A1JC 3GPMA 5H0TA 1AXCA 4CS5A 2NTIB 3A2FB 3AIZA 2IJXA 3G65B 3TBLA 1SXJF 2HIKA 5IY4A 2ZVKA 5IWDA 3GGRA 3LX1A 2IZOB 3WGWA 2ZVWA 3AIXA 3P91A 3AIZC 1IZ5A 2ZVLA 1VYMA 3VKXA 5E0VA 2HIKC 1YYPA 1ISQA 5E0TA 5B7OA 5DA7A 1B8HA 1W60A 3GGRC 3HI8A 2ZVVA 1DMLA 4L6PA 2NTIA 3G65A 1RXMA 1UD9A 3V62B 2AVTA 5IXAA 3U60F 1PLQA 3LX2A 2NTIC 3G65C 2IX2B 3FDSC 4RJFA 3HSLX 2AWAA 3GPNA 2HIIB 3A1JB 3GGRB 1GE8A 3IFVA 4D2GA 2IO4B 1RWZA 1CZDA 2IZOC 5DAIA 1VYJA 1U76A 4L60A 2ZVMA 5AUJA 3F1WA 1RXZA 3V60B 5CFKA 5HACA 2OD8A 1T6LA 3U5ZF 5JNED 1U7BA 1B77A 2Z0LA 1IZ4A 2IX2A 3FDSD 2HIKB 1UL1A 4YHRA 3K4XA 2HIIA 3A1JA 3V61B 5E0UA 2IO4A 4ZTDA 5A6DA 3I2MX 3AIXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IX2 C;  3P83 A;  4TR6 A;  3U61 F;  1PLR A;  4HK1 A;  2HII C;  3P87 A;  3A1J C;  3GPM A;  5H0T A;  1AXC A;  4CS5 A;  2NTI B;  3A2F B;  3AIZ A;  2IJX A;  3G65 B;  3TBL A;  1SXJ F;  2HIK A;  5IY4 A;  2ZVK A;  5IWD A;  3GGR A;  3LX1 A;  2IZO B;  3WGW A;  2ZVW A;  3AIX A;  3P91 A;  3AIZ C;  1IZ5 A;  2ZVL A;  1VYM A;  3VKX A;  5E0V A;  2HIK C;  1YYP A;  1ISQ A;  5E0T A;  5B7O A;  5DA7 A;  1B8H A;  1W60 A;  3GGR C;  3HI8 A;  2ZVV A;  1DML A;  4L6P A;  2NTI A;  3G65 A;  1RXM A;  1UD9 A;  3V62 B;  2AVT A;  5IXA A;  3U60 F;  1PLQ A;  3LX2 A;  2NTI C;  3G65 C;  2IX2 B;  3FDS C;  4RJF A;  3HSL X;  2AWA A;  3GPN A;  2HII B;  3A1J B;  3GGR B;  1GE8 A;  3IFV A;  4D2G A;  2IO4 B;  1RWZ A;  1CZD A;  2IZO C;  5DAI A;  1VYJ A;  1U76 A;  4L60 A;  2ZVM A;  5AUJ A;  3F1W A;  1RXZ A;  3V60 B;  5CFK A;  5HAC A;  2OD8 A;  1T6L A;  3U5Z F;  5JNE D;  1U7B A;  1B77 A;  2Z0L A;  1IZ4 A;  2IX2 A;  3FDS D;  2HIK B;  1UL1 A;  4YHR A;  3K4X A;  2HII A;  3A1J A;  3V61 B;  5E0U A;  2IO4 A;  4ZTD A;  5A6D A;  3I2M X;  3AIX B; 
#chains in the Genus database with same CATH topology
 2IX2 C;  3P83 A;  4TR6 A;  3U61 F;  1PLR A;  4HK1 A;  2HII C;  3P87 A;  3A1J C;  3GPM A;  5H0T A;  1AXC A;  4CS5 A;  2NTI B;  3A2F B;  3AIZ A;  2IJX A;  3G65 B;  3TBL A;  1SXJ F;  2HIK A;  5IY4 A;  2ZVK A;  5IWD A;  3GGR A;  3LX1 A;  2IZO B;  3WGW A;  2ZVW A;  3AIX A;  3P91 A;  3AIZ C;  1IZ5 A;  2ZVL A;  1VYM A;  3VKX A;  5E0V A;  2HIK C;  1YYP A;  1ISQ A;  5E0T A;  5B7O A;  5DA7 A;  1B8H A;  1W60 A;  3GGR C;  3HI8 A;  2ZVV A;  1DML A;  4L6P A;  2NTI A;  3G65 A;  1RXM A;  1UD9 A;  3V62 B;  2AVT A;  5IXA A;  3U60 F;  1PLQ A;  3LX2 A;  2NTI C;  3G65 C;  2IX2 B;  3FDS C;  4RJF A;  3HSL X;  2AWA A;  3GPN A;  2HII B;  3A1J B;  3GGR B;  1GE8 A;  3IFV A;  4D2G A;  2IO4 B;  1RWZ A;  1CZD A;  2IZO C;  5DAI A;  1VYJ A;  1U76 A;  4L60 A;  2ZVM A;  5AUJ A;  3F1W A;  1RXZ A;  3V60 B;  5CFK A;  5HAC A;  2OD8 A;  1T6L A;  3U5Z F;  5JNE D;  1U7B A;  1B77 A;  2Z0L A;  1IZ4 A;  2IX2 A;  3FDS D;  2HIK B;  1UL1 A;  4YHR A;  3K4X A;  2HII A;  3A1J A;  3V61 B;  5E0U A;  2IO4 A;  4ZTD A;  5A6D A;  3I2M X;  3AIX B; 
#chains in the Genus database with same CATH homology
 2IX2 C;  3P83 A;  4TR6 A;  3U61 F;  1PLR A;  4HK1 A;  2HII C;  3P87 A;  3A1J C;  3GPM A;  5H0T A;  1AXC A;  4CS5 A;  2NTI B;  3A2F B;  3AIZ A;  2IJX A;  3G65 B;  3TBL A;  1SXJ F;  2HIK A;  5IY4 A;  2ZVK A;  5IWD A;  3GGR A;  3LX1 A;  2IZO B;  3WGW A;  2ZVW A;  3AIX A;  3P91 A;  3AIZ C;  1IZ5 A;  2ZVL A;  1VYM A;  3VKX A;  5E0V A;  2HIK C;  1YYP A;  1ISQ A;  5E0T A;  5B7O A;  5DA7 A;  1B8H A;  1W60 A;  3GGR C;  3HI8 A;  2ZVV A;  1DML A;  4L6P A;  2NTI A;  3G65 A;  1RXM A;  1UD9 A;  3V62 B;  2AVT A;  5IXA A;  3U60 F;  1PLQ A;  3LX2 A;  2NTI C;  3G65 C;  2IX2 B;  3FDS C;  4RJF A;  3HSL X;  2AWA A;  3GPN A;  2HII B;  3A1J B;  3GGR B;  1GE8 A;  3IFV A;  4D2G A;  2IO4 B;  1RWZ A;  1CZD A;  2IZO C;  5DAI A;  1VYJ A;  1U76 A;  4L60 A;  2ZVM A;  5AUJ A;  3F1W A;  1RXZ A;  3V60 B;  5CFK A;  5HAC A;  2OD8 A;  1T6L A;  3U5Z F;  5JNE D;  1U7B A;  1B77 A;  2Z0L A;  1IZ4 A;  2IX2 A;  3FDS D;  2HIK B;  1UL1 A;  4YHR A;  3K4X A;  2HII A;  3A1J A;  3V61 B;  5E0U A;  2IO4 A;  4ZTD A;  5A6D A;  3I2M X;  3AIX B; 
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similar chains in the Genus database (?% sequence similarity)
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