1IZ5A

Pyrococcus furiosus pcna mutant (met73leu, asp143ala, asp147ala): orthorhombic form
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
245
structure length
240
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEEPELPFTAKVVVLGEVLKAAVKAASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
pubmed doi rcsb
molecule tags Dna binding protein
source organism Pyrococcus furiosus
molecule keywords Proliferating cell nuclear antigen
total genus 60
structure length 240
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1iz5A00
1PLRA 5DAIA 3G65C 3HSLX 2HIIA 2IX2A 4L6PA 4YHRA 3GGRA 1IZ5A 3GPNA 3V60B 2HIIC 2IX2C 2ZVVA 5CFKA 1UD9A 3V61B 3P83A 3GGRC 5H0TA 3G65B 3AIZA 3F1WA 2HIKA 4D2GA 3LX2A 2IZOB 1YYPA 3AIXA 3AIZC 2HIIB 2HIKC 2IX2B 3FDSC 1RWZA 4CS5A 1UL1A 2IO4A 5HACA 5E0TA 3U5ZF 3GGRB 4TR6A 3K4XA 1IZ4A 3U60F 2NTIA 3P91A 3FDSD 1RXMA 5IY4A 3P87A 5E0VA 2HIKB 5A6DA 1U76A 5IXAA 3A2FB 1T6LA 2AVTA 3U61F 3TBLA 3AIXB 1SXJF 1ISQA 2AWAA 2IJXA 4RJFA 3VKXA 3A1JA 3HI8A 1CZDA 4HK1A 5IWDA 4ZTDA 1AXCA 1VYJA 3A1JC 3G65A 1B8HA 3GPMA 4L60A 5AUJA 1PLQA 3IFVA 1W60A 5E0UA 3I2MX 2ZVMA 2NTIC 3LX1A 1VYMA 3WGWA 2IZOC 2ZVWA 2Z0LA 2ZVKA 3A1JB 2IO4B 1B77A 1U7BA 2OD8A 5JNED 3V62B 5DA7A 2NTIB 1DMLA 1RXZA 2ZVLA 1GE8A 5B7OA
chains in the Genus database with same CATH superfamily
1PLRA 5DAIA 3G65C 3HSLX 2HIIA 2IX2A 4L6PA 4YHRA 3GGRA 1IZ5A 3GPNA 3V60B 2HIIC 2IX2C 2ZVVA 5CFKA 1UD9A 3V61B 3P83A 3GGRC 5H0TA 3G65B 3AIZA 3F1WA 2HIKA 4D2GA 3LX2A 2IZOB 1YYPA 3AIXA 3AIZC 2HIIB 2HIKC 2IX2B 3FDSC 1RWZA 4CS5A 1UL1A 2IO4A 5HACA 5E0TA 3U5ZF 3GGRB 4TR6A 3K4XA 1IZ4A 3U60F 2NTIA 3P91A 3FDSD 1RXMA 5IY4A 3P87A 5E0VA 2HIKB 5A6DA 1U76A 5IXAA 3A2FB 1T6LA 2AVTA 3U61F 3TBLA 3AIXB 1SXJF 1ISQA 2AWAA 2IJXA 4RJFA 3VKXA 3A1JA 3HI8A 1CZDA 4HK1A 5IWDA 4ZTDA 1AXCA 1VYJA 3A1JC 3G65A 1B8HA 3GPMA 4L60A 5AUJA 1PLQA 3IFVA 1W60A 5E0UA 3I2MX 2ZVMA 2NTIC 3LX1A 1VYMA 3WGWA 2IZOC 2ZVWA 2Z0LA 2ZVKA 3A1JB 2IO4B 1B77A 1U7BA 2OD8A 5JNED 3V62B 5DA7A 2NTIB 1DMLA 1RXZA 2ZVLA 1GE8A 5B7OA
chains in the Genus database with same CATH topology
1PLRA 5DAIA 3G65C 3HSLX 2HIIA 2IX2A 4L6PA 4YHRA 3GGRA 1IZ5A 3GPNA 3V60B 2HIIC 2IX2C 2ZVVA 5CFKA 1UD9A 3V61B 3P83A 3GGRC 5H0TA 3G65B 3AIZA 3F1WA 2HIKA 4D2GA 3LX2A 2IZOB 1YYPA 3AIXA 3AIZC 2HIIB 2HIKC 2IX2B 3FDSC 1RWZA 4CS5A 1UL1A 2IO4A 5HACA 5E0TA 3U5ZF 3GGRB 4TR6A 3K4XA 1IZ4A 3U60F 2NTIA 3P91A 3FDSD 1RXMA 5IY4A 3P87A 5E0VA 2HIKB 5A6DA 1U76A 5IXAA 3A2FB 1T6LA 2AVTA 3U61F 3TBLA 3AIXB 1SXJF 1ISQA 2AWAA 2IJXA 4RJFA 3VKXA 3A1JA 3HI8A 1CZDA 4HK1A 5IWDA 4ZTDA 1AXCA 1VYJA 3A1JC 3G65A 1B8HA 3GPMA 4L60A 5AUJA 1PLQA 3IFVA 1W60A 5E0UA 3I2MX 2ZVMA 2NTIC 3LX1A 1VYMA 3WGWA 2IZOC 2ZVWA 2Z0LA 2ZVKA 3A1JB 2IO4B 1B77A 1U7BA 2OD8A 5JNED 3V62B 5DA7A 2NTIB 1DMLA 1RXZA 2ZVLA 1GE8A 5B7OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PLR A;  5DAI A;  3G65 C;  3HSL X;  2HII A;  2IX2 A;  4L6P A;  4YHR A;  3GGR A;  1IZ5 A;  3GPN A;  3V60 B;  2HII C;  2IX2 C;  2ZVV A;  5CFK A;  1UD9 A;  3V61 B;  3P83 A;  3GGR C;  5H0T A;  3G65 B;  3AIZ A;  3F1W A;  2HIK A;  4D2G A;  3LX2 A;  2IZO B;  1YYP A;  3AIX A;  3AIZ C;  2HII B;  2HIK C;  2IX2 B;  3FDS C;  1RWZ A;  4CS5 A;  1UL1 A;  2IO4 A;  5HAC A;  5E0T A;  3U5Z F;  3GGR B;  4TR6 A;  3K4X A;  1IZ4 A;  3U60 F;  2NTI A;  3P91 A;  3FDS D;  1RXM A;  5IY4 A;  3P87 A;  5E0V A;  2HIK B;  5A6D A;  1U76 A;  5IXA A;  3A2F B;  1T6L A;  2AVT A;  3U61 F;  3TBL A;  3AIX B;  1SXJ F;  1ISQ A;  2AWA A;  2IJX A;  4RJF A;  3VKX A;  3A1J A;  3HI8 A;  1CZD A;  4HK1 A;  5IWD A;  4ZTD A;  1AXC A;  1VYJ A;  3A1J C;  3G65 A;  1B8H A;  3GPM A;  4L60 A;  5AUJ A;  1PLQ A;  3IFV A;  1W60 A;  5E0U A;  3I2M X;  2ZVM A;  2NTI C;  3LX1 A;  1VYM A;  3WGW A;  2IZO C;  2ZVW A;  2Z0L A;  2ZVK A;  3A1J B;  2IO4 B;  1B77 A;  1U7B A;  2OD8 A;  5JNE D;  3V62 B;  5DA7 A;  2NTI B;  1DML A;  1RXZ A;  2ZVL A;  1GE8 A;  5B7O A; 
#chains in the Genus database with same CATH topology
 1PLR A;  5DAI A;  3G65 C;  3HSL X;  2HII A;  2IX2 A;  4L6P A;  4YHR A;  3GGR A;  1IZ5 A;  3GPN A;  3V60 B;  2HII C;  2IX2 C;  2ZVV A;  5CFK A;  1UD9 A;  3V61 B;  3P83 A;  3GGR C;  5H0T A;  3G65 B;  3AIZ A;  3F1W A;  2HIK A;  4D2G A;  3LX2 A;  2IZO B;  1YYP A;  3AIX A;  3AIZ C;  2HII B;  2HIK C;  2IX2 B;  3FDS C;  1RWZ A;  4CS5 A;  1UL1 A;  2IO4 A;  5HAC A;  5E0T A;  3U5Z F;  3GGR B;  4TR6 A;  3K4X A;  1IZ4 A;  3U60 F;  2NTI A;  3P91 A;  3FDS D;  1RXM A;  5IY4 A;  3P87 A;  5E0V A;  2HIK B;  5A6D A;  1U76 A;  5IXA A;  3A2F B;  1T6L A;  2AVT A;  3U61 F;  3TBL A;  3AIX B;  1SXJ F;  1ISQ A;  2AWA A;  2IJX A;  4RJF A;  3VKX A;  3A1J A;  3HI8 A;  1CZD A;  4HK1 A;  5IWD A;  4ZTD A;  1AXC A;  1VYJ A;  3A1J C;  3G65 A;  1B8H A;  3GPM A;  4L60 A;  5AUJ A;  1PLQ A;  3IFV A;  1W60 A;  5E0U A;  3I2M X;  2ZVM A;  2NTI C;  3LX1 A;  1VYM A;  3WGW A;  2IZO C;  2ZVW A;  2Z0L A;  2ZVK A;  3A1J B;  2IO4 B;  1B77 A;  1U7B A;  2OD8 A;  5JNE D;  3V62 B;  5DA7 A;  2NTI B;  1DML A;  1RXZ A;  2ZVL A;  1GE8 A;  5B7O A; 
#chains in the Genus database with same CATH homology
 1PLR A;  5DAI A;  3G65 C;  3HSL X;  2HII A;  2IX2 A;  4L6P A;  4YHR A;  3GGR A;  1IZ5 A;  3GPN A;  3V60 B;  2HII C;  2IX2 C;  2ZVV A;  5CFK A;  1UD9 A;  3V61 B;  3P83 A;  3GGR C;  5H0T A;  3G65 B;  3AIZ A;  3F1W A;  2HIK A;  4D2G A;  3LX2 A;  2IZO B;  1YYP A;  3AIX A;  3AIZ C;  2HII B;  2HIK C;  2IX2 B;  3FDS C;  1RWZ A;  4CS5 A;  1UL1 A;  2IO4 A;  5HAC A;  5E0T A;  3U5Z F;  3GGR B;  4TR6 A;  3K4X A;  1IZ4 A;  3U60 F;  2NTI A;  3P91 A;  3FDS D;  1RXM A;  5IY4 A;  3P87 A;  5E0V A;  2HIK B;  5A6D A;  1U76 A;  5IXA A;  3A2F B;  1T6L A;  2AVT A;  3U61 F;  3TBL A;  3AIX B;  1SXJ F;  1ISQ A;  2AWA A;  2IJX A;  4RJF A;  3VKX A;  3A1J A;  3HI8 A;  1CZD A;  4HK1 A;  5IWD A;  4ZTD A;  1AXC A;  1VYJ A;  3A1J C;  3G65 A;  1B8H A;  3GPM A;  4L60 A;  5AUJ A;  1PLQ A;  3IFV A;  1W60 A;  5E0U A;  3I2M X;  2ZVM A;  2NTI C;  3LX1 A;  1VYM A;  3WGW A;  2IZO C;  2ZVW A;  2Z0L A;  2ZVK A;  3A1J B;  2IO4 B;  1B77 A;  1U7B A;  2OD8 A;  5JNE D;  3V62 B;  5DA7 A;  2NTI B;  1DML A;  1RXZ A;  2ZVL A;  1GE8 A;  5B7O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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