1PLRA

Crystal structure of the eukaryotic dna polymerase processivity factor pcna
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
258
structure length
258
Chain Sequence
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFNDEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
pubmed doi rcsb
molecule tags Dna-binding
source organism Saccharomyces cerevisiae
molecule keywords PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
total genus 58
structure length 258
sequence length 258
ec nomenclature
pdb deposition date 1995-01-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1plrA00
2ZVWA 3K4XA 2NTIB 2IO4B 3G65C 3A1JA 3LX2A 5B7OA 3GPNA 1PLRA 3GGRA 3VKXA 2HIIB 3U61F 5JNED 1YYPA 5H0TA 3AIXA 1B8HA 2IX2B 3F1WA 1SXJF 3G65A 2HIKB 1CZDA 2IJXA 1AXCA 3GGRB 1VYMA 1UD9A 2AWAA 3V60B 1ISQA 3HSLX 3IFVA 2AVTA 4RJFA 1VYJA 4HK1A 5E0UA 5IWDA 5E0TA 3V62B 3AIZC 1W60A 1U76A 2IZOC 3P87A 4YHRA 3A1JB 1IZ5A 3GPMA 2NTIC 1DMLA 3AIZA 3AIXB 1RXZA 1IZ4A 4ZTDA 3G65B 2HIIC 5E0VA 2Z0LA 3P91A 3HI8A 2IX2C 2NTIA 1B77A 3TBLA 3U5ZF 2HIKC 2ZVLA 2ZVMA 2HIIA 1RWZA 5CFKA 2IZOB 2IX2A 4D2GA 4L60A 5DAIA 3I2MX 2HIKA 3FDSC 4L6PA 4CS5A 2ZVVA 3P83A 3V61B 3FDSD 5IXAA 3LX1A 3A2FB 3U60F 1PLQA 1U7BA 5AUJA 2OD8A 2IO4A 5A6DA 2ZVKA 3WGWA 1GE8A 5DA7A 5HACA 1RXMA 1T6LA 5IY4A 4TR6A 3A1JC 3GGRC 1UL1A
chains in the Genus database with same CATH superfamily
2ZVWA 3K4XA 2NTIB 2IO4B 3G65C 3A1JA 3LX2A 5B7OA 3GPNA 1PLRA 3GGRA 3VKXA 2HIIB 3U61F 5JNED 1YYPA 5H0TA 3AIXA 1B8HA 2IX2B 3F1WA 1SXJF 3G65A 2HIKB 1CZDA 2IJXA 1AXCA 3GGRB 1VYMA 1UD9A 2AWAA 3V60B 1ISQA 3HSLX 3IFVA 2AVTA 4RJFA 1VYJA 4HK1A 5E0UA 5IWDA 5E0TA 3V62B 3AIZC 1W60A 1U76A 2IZOC 3P87A 4YHRA 3A1JB 1IZ5A 3GPMA 2NTIC 1DMLA 3AIZA 3AIXB 1RXZA 1IZ4A 4ZTDA 3G65B 2HIIC 5E0VA 2Z0LA 3P91A 3HI8A 2IX2C 2NTIA 1B77A 3TBLA 3U5ZF 2HIKC 2ZVLA 2ZVMA 2HIIA 1RWZA 5CFKA 2IZOB 2IX2A 4D2GA 4L60A 5DAIA 3I2MX 2HIKA 3FDSC 4L6PA 4CS5A 2ZVVA 3P83A 3V61B 3FDSD 5IXAA 3LX1A 3A2FB 3U60F 1PLQA 1U7BA 5AUJA 2OD8A 2IO4A 5A6DA 2ZVKA 3WGWA 1GE8A 5DA7A 5HACA 1RXMA 1T6LA 5IY4A 4TR6A 3A1JC 3GGRC 1UL1A
chains in the Genus database with same CATH topology
2ZVWA 3K4XA 2NTIB 2IO4B 3G65C 3A1JA 3LX2A 5B7OA 3GPNA 1PLRA 3GGRA 3VKXA 2HIIB 3U61F 5JNED 1YYPA 5H0TA 3AIXA 1B8HA 2IX2B 3F1WA 1SXJF 3G65A 2HIKB 1CZDA 2IJXA 1AXCA 3GGRB 1VYMA 1UD9A 2AWAA 3V60B 1ISQA 3HSLX 3IFVA 2AVTA 4RJFA 1VYJA 4HK1A 5E0UA 5IWDA 5E0TA 3V62B 3AIZC 1W60A 1U76A 2IZOC 3P87A 4YHRA 3A1JB 1IZ5A 3GPMA 2NTIC 1DMLA 3AIZA 3AIXB 1RXZA 1IZ4A 4ZTDA 3G65B 2HIIC 5E0VA 2Z0LA 3P91A 3HI8A 2IX2C 2NTIA 1B77A 3TBLA 3U5ZF 2HIKC 2ZVLA 2ZVMA 2HIIA 1RWZA 5CFKA 2IZOB 2IX2A 4D2GA 4L60A 5DAIA 3I2MX 2HIKA 3FDSC 4L6PA 4CS5A 2ZVVA 3P83A 3V61B 3FDSD 5IXAA 3LX1A 3A2FB 3U60F 1PLQA 1U7BA 5AUJA 2OD8A 2IO4A 5A6DA 2ZVKA 3WGWA 1GE8A 5DA7A 5HACA 1RXMA 1T6LA 5IY4A 4TR6A 3A1JC 3GGRC 1UL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVW A;  3K4X A;  2NTI B;  2IO4 B;  3G65 C;  3A1J A;  3LX2 A;  5B7O A;  3GPN A;  1PLR A;  3GGR A;  3VKX A;  2HII B;  3U61 F;  5JNE D;  1YYP A;  5H0T A;  3AIX A;  1B8H A;  2IX2 B;  3F1W A;  1SXJ F;  3G65 A;  2HIK B;  1CZD A;  2IJX A;  1AXC A;  3GGR B;  1VYM A;  1UD9 A;  2AWA A;  3V60 B;  1ISQ A;  3HSL X;  3IFV A;  2AVT A;  4RJF A;  1VYJ A;  4HK1 A;  5E0U A;  5IWD A;  5E0T A;  3V62 B;  3AIZ C;  1W60 A;  1U76 A;  2IZO C;  3P87 A;  4YHR A;  3A1J B;  1IZ5 A;  3GPM A;  2NTI C;  1DML A;  3AIZ A;  3AIX B;  1RXZ A;  1IZ4 A;  4ZTD A;  3G65 B;  2HII C;  5E0V A;  2Z0L A;  3P91 A;  3HI8 A;  2IX2 C;  2NTI A;  1B77 A;  3TBL A;  3U5Z F;  2HIK C;  2ZVL A;  2ZVM A;  2HII A;  1RWZ A;  5CFK A;  2IZO B;  2IX2 A;  4D2G A;  4L60 A;  5DAI A;  3I2M X;  2HIK A;  3FDS C;  4L6P A;  4CS5 A;  2ZVV A;  3P83 A;  3V61 B;  3FDS D;  5IXA A;  3LX1 A;  3A2F B;  3U60 F;  1PLQ A;  1U7B A;  5AUJ A;  2OD8 A;  2IO4 A;  5A6D A;  2ZVK A;  3WGW A;  1GE8 A;  5DA7 A;  5HAC A;  1RXM A;  1T6L A;  5IY4 A;  4TR6 A;  3A1J C;  3GGR C;  1UL1 A; 
#chains in the Genus database with same CATH topology
 2ZVW A;  3K4X A;  2NTI B;  2IO4 B;  3G65 C;  3A1J A;  3LX2 A;  5B7O A;  3GPN A;  1PLR A;  3GGR A;  3VKX A;  2HII B;  3U61 F;  5JNE D;  1YYP A;  5H0T A;  3AIX A;  1B8H A;  2IX2 B;  3F1W A;  1SXJ F;  3G65 A;  2HIK B;  1CZD A;  2IJX A;  1AXC A;  3GGR B;  1VYM A;  1UD9 A;  2AWA A;  3V60 B;  1ISQ A;  3HSL X;  3IFV A;  2AVT A;  4RJF A;  1VYJ A;  4HK1 A;  5E0U A;  5IWD A;  5E0T A;  3V62 B;  3AIZ C;  1W60 A;  1U76 A;  2IZO C;  3P87 A;  4YHR A;  3A1J B;  1IZ5 A;  3GPM A;  2NTI C;  1DML A;  3AIZ A;  3AIX B;  1RXZ A;  1IZ4 A;  4ZTD A;  3G65 B;  2HII C;  5E0V A;  2Z0L A;  3P91 A;  3HI8 A;  2IX2 C;  2NTI A;  1B77 A;  3TBL A;  3U5Z F;  2HIK C;  2ZVL A;  2ZVM A;  2HII A;  1RWZ A;  5CFK A;  2IZO B;  2IX2 A;  4D2G A;  4L60 A;  5DAI A;  3I2M X;  2HIK A;  3FDS C;  4L6P A;  4CS5 A;  2ZVV A;  3P83 A;  3V61 B;  3FDS D;  5IXA A;  3LX1 A;  3A2F B;  3U60 F;  1PLQ A;  1U7B A;  5AUJ A;  2OD8 A;  2IO4 A;  5A6D A;  2ZVK A;  3WGW A;  1GE8 A;  5DA7 A;  5HAC A;  1RXM A;  1T6L A;  5IY4 A;  4TR6 A;  3A1J C;  3GGR C;  1UL1 A; 
#chains in the Genus database with same CATH homology
 2ZVW A;  3K4X A;  2NTI B;  2IO4 B;  3G65 C;  3A1J A;  3LX2 A;  5B7O A;  3GPN A;  1PLR A;  3GGR A;  3VKX A;  2HII B;  3U61 F;  5JNE D;  1YYP A;  5H0T A;  3AIX A;  1B8H A;  2IX2 B;  3F1W A;  1SXJ F;  3G65 A;  2HIK B;  1CZD A;  2IJX A;  1AXC A;  3GGR B;  1VYM A;  1UD9 A;  2AWA A;  3V60 B;  1ISQ A;  3HSL X;  3IFV A;  2AVT A;  4RJF A;  1VYJ A;  4HK1 A;  5E0U A;  5IWD A;  5E0T A;  3V62 B;  3AIZ C;  1W60 A;  1U76 A;  2IZO C;  3P87 A;  4YHR A;  3A1J B;  1IZ5 A;  3GPM A;  2NTI C;  1DML A;  3AIZ A;  3AIX B;  1RXZ A;  1IZ4 A;  4ZTD A;  3G65 B;  2HII C;  5E0V A;  2Z0L A;  3P91 A;  3HI8 A;  2IX2 C;  2NTI A;  1B77 A;  3TBL A;  3U5Z F;  2HIK C;  2ZVL A;  2ZVM A;  2HII A;  1RWZ A;  5CFK A;  2IZO B;  2IX2 A;  4D2G A;  4L60 A;  5DAI A;  3I2M X;  2HIK A;  3FDS C;  4L6P A;  4CS5 A;  2ZVV A;  3P83 A;  3V61 B;  3FDS D;  5IXA A;  3LX1 A;  3A2F B;  3U60 F;  1PLQ A;  1U7B A;  5AUJ A;  2OD8 A;  2IO4 A;  5A6D A;  2ZVK A;  3WGW A;  1GE8 A;  5DA7 A;  5HAC A;  1RXM A;  1T6L A;  5IY4 A;  4TR6 A;  3A1J C;  3GGR C;  1UL1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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