1RXMA

C-terminal region of fen-1 bound to a. fulgidus pcna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
245
structure length
245
Chain Sequence
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
pubmed doi rcsb
molecule tags Replication
source organism Archaeoglobus fulgidus
molecule keywords DNA polymerase sliding clamp
total genus 62
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2003-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1rxmA00
5HACA 5B7OA 4HK1A 2IX2C 2IZOC 2HIKB 3AIZA 3WGWA 1B77A 5H0TA 1CZDA 3GPNA 2ZVLA 2IO4B 2IX2B 3V61B 1RWZA 2HIKA 2ZVWA 1B8HA 3U5ZF 2OD8A 2AVTA 5AUJA 2HIIC 3P87A 2IO4A 2IX2A 3P83A 5DAIA 4RJFA 3GPMA 3FDSD 2IJXA 2ZVVA 5E0VA 1PLRA 2NTIC 2HIIB 3I2MX 1UL1A 3U60F 3GGRC 4TR6A 1RXZA 1UD9A 3F1WA 3A2FB 1VYMA 1IZ5A 3P91A 1YYPA 5E0UA 2HIIA 1AXCA 2NTIB 3G65C 3GGRB 2ZVKA 5A6DA 1DMLA 3VKXA 5IY4A 3HSLX 3A1JC 4D2GA 1SXJF 2NTIA 3LX2A 5IXAA 3FDSC 1GE8A 4CS5A 3GGRA 3G65B 1IZ4A 1U76A 5E0TA 5JNED 1VYJA 3V60B 4ZTDA 1T6LA 4L6PA 3A1JB 2AWAA 1ISQA 3G65A 3IFVA 4L60A 3K4XA 3AIZC 1W60A 3HI8A 1PLQA 3AIXB 5DA7A 2Z0LA 2ZVMA 3A1JA 3TBLA 1U7BA 3V62B 1RXMA 2IZOB 3LX1A 2HIKC 3U61F 5CFKA 5IWDA 4YHRA 3AIXA
chains in the Genus database with same CATH superfamily
5HACA 5B7OA 4HK1A 2IX2C 2IZOC 2HIKB 3AIZA 3WGWA 1B77A 5H0TA 1CZDA 3GPNA 2ZVLA 2IO4B 2IX2B 3V61B 1RWZA 2HIKA 2ZVWA 1B8HA 3U5ZF 2OD8A 2AVTA 5AUJA 2HIIC 3P87A 2IO4A 2IX2A 3P83A 5DAIA 4RJFA 3GPMA 3FDSD 2IJXA 2ZVVA 5E0VA 1PLRA 2NTIC 2HIIB 3I2MX 1UL1A 3U60F 3GGRC 4TR6A 1RXZA 1UD9A 3F1WA 3A2FB 1VYMA 1IZ5A 3P91A 1YYPA 5E0UA 2HIIA 1AXCA 2NTIB 3G65C 3GGRB 2ZVKA 5A6DA 1DMLA 3VKXA 5IY4A 3HSLX 3A1JC 4D2GA 1SXJF 2NTIA 3LX2A 5IXAA 3FDSC 1GE8A 4CS5A 3GGRA 3G65B 1IZ4A 1U76A 5E0TA 5JNED 1VYJA 3V60B 4ZTDA 1T6LA 4L6PA 3A1JB 2AWAA 1ISQA 3G65A 3IFVA 4L60A 3K4XA 3AIZC 1W60A 3HI8A 1PLQA 3AIXB 5DA7A 2Z0LA 2ZVMA 3A1JA 3TBLA 1U7BA 3V62B 1RXMA 2IZOB 3LX1A 2HIKC 3U61F 5CFKA 5IWDA 4YHRA 3AIXA
chains in the Genus database with same CATH topology
5HACA 5B7OA 4HK1A 2IX2C 2IZOC 2HIKB 3AIZA 3WGWA 1B77A 5H0TA 1CZDA 3GPNA 2ZVLA 2IO4B 2IX2B 3V61B 1RWZA 2HIKA 2ZVWA 1B8HA 3U5ZF 2OD8A 2AVTA 5AUJA 2HIIC 3P87A 2IO4A 2IX2A 3P83A 5DAIA 4RJFA 3GPMA 3FDSD 2IJXA 2ZVVA 5E0VA 1PLRA 2NTIC 2HIIB 3I2MX 1UL1A 3U60F 3GGRC 4TR6A 1RXZA 1UD9A 3F1WA 3A2FB 1VYMA 1IZ5A 3P91A 1YYPA 5E0UA 2HIIA 1AXCA 2NTIB 3G65C 3GGRB 2ZVKA 5A6DA 1DMLA 3VKXA 5IY4A 3HSLX 3A1JC 4D2GA 1SXJF 2NTIA 3LX2A 5IXAA 3FDSC 1GE8A 4CS5A 3GGRA 3G65B 1IZ4A 1U76A 5E0TA 5JNED 1VYJA 3V60B 4ZTDA 1T6LA 4L6PA 3A1JB 2AWAA 1ISQA 3G65A 3IFVA 4L60A 3K4XA 3AIZC 1W60A 3HI8A 1PLQA 3AIXB 5DA7A 2Z0LA 2ZVMA 3A1JA 3TBLA 1U7BA 3V62B 1RXMA 2IZOB 3LX1A 2HIKC 3U61F 5CFKA 5IWDA 4YHRA 3AIXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HAC A;  5B7O A;  4HK1 A;  2IX2 C;  2IZO C;  2HIK B;  3AIZ A;  3WGW A;  1B77 A;  5H0T A;  1CZD A;  3GPN A;  2ZVL A;  2IO4 B;  2IX2 B;  3V61 B;  1RWZ A;  2HIK A;  2ZVW A;  1B8H A;  3U5Z F;  2OD8 A;  2AVT A;  5AUJ A;  2HII C;  3P87 A;  2IO4 A;  2IX2 A;  3P83 A;  5DAI A;  4RJF A;  3GPM A;  3FDS D;  2IJX A;  2ZVV A;  5E0V A;  1PLR A;  2NTI C;  2HII B;  3I2M X;  1UL1 A;  3U60 F;  3GGR C;  4TR6 A;  1RXZ A;  1UD9 A;  3F1W A;  3A2F B;  1VYM A;  1IZ5 A;  3P91 A;  1YYP A;  5E0U A;  2HII A;  1AXC A;  2NTI B;  3G65 C;  3GGR B;  2ZVK A;  5A6D A;  1DML A;  3VKX A;  5IY4 A;  3HSL X;  3A1J C;  4D2G A;  1SXJ F;  2NTI A;  3LX2 A;  5IXA A;  3FDS C;  1GE8 A;  4CS5 A;  3GGR A;  3G65 B;  1IZ4 A;  1U76 A;  5E0T A;  5JNE D;  1VYJ A;  3V60 B;  4ZTD A;  1T6L A;  4L6P A;  3A1J B;  2AWA A;  1ISQ A;  3G65 A;  3IFV A;  4L60 A;  3K4X A;  3AIZ C;  1W60 A;  3HI8 A;  1PLQ A;  3AIX B;  5DA7 A;  2Z0L A;  2ZVM A;  3A1J A;  3TBL A;  1U7B A;  3V62 B;  1RXM A;  2IZO B;  3LX1 A;  2HIK C;  3U61 F;  5CFK A;  5IWD A;  4YHR A;  3AIX A; 
#chains in the Genus database with same CATH topology
 5HAC A;  5B7O A;  4HK1 A;  2IX2 C;  2IZO C;  2HIK B;  3AIZ A;  3WGW A;  1B77 A;  5H0T A;  1CZD A;  3GPN A;  2ZVL A;  2IO4 B;  2IX2 B;  3V61 B;  1RWZ A;  2HIK A;  2ZVW A;  1B8H A;  3U5Z F;  2OD8 A;  2AVT A;  5AUJ A;  2HII C;  3P87 A;  2IO4 A;  2IX2 A;  3P83 A;  5DAI A;  4RJF A;  3GPM A;  3FDS D;  2IJX A;  2ZVV A;  5E0V A;  1PLR A;  2NTI C;  2HII B;  3I2M X;  1UL1 A;  3U60 F;  3GGR C;  4TR6 A;  1RXZ A;  1UD9 A;  3F1W A;  3A2F B;  1VYM A;  1IZ5 A;  3P91 A;  1YYP A;  5E0U A;  2HII A;  1AXC A;  2NTI B;  3G65 C;  3GGR B;  2ZVK A;  5A6D A;  1DML A;  3VKX A;  5IY4 A;  3HSL X;  3A1J C;  4D2G A;  1SXJ F;  2NTI A;  3LX2 A;  5IXA A;  3FDS C;  1GE8 A;  4CS5 A;  3GGR A;  3G65 B;  1IZ4 A;  1U76 A;  5E0T A;  5JNE D;  1VYJ A;  3V60 B;  4ZTD A;  1T6L A;  4L6P A;  3A1J B;  2AWA A;  1ISQ A;  3G65 A;  3IFV A;  4L60 A;  3K4X A;  3AIZ C;  1W60 A;  3HI8 A;  1PLQ A;  3AIX B;  5DA7 A;  2Z0L A;  2ZVM A;  3A1J A;  3TBL A;  1U7B A;  3V62 B;  1RXM A;  2IZO B;  3LX1 A;  2HIK C;  3U61 F;  5CFK A;  5IWD A;  4YHR A;  3AIX A; 
#chains in the Genus database with same CATH homology
 5HAC A;  5B7O A;  4HK1 A;  2IX2 C;  2IZO C;  2HIK B;  3AIZ A;  3WGW A;  1B77 A;  5H0T A;  1CZD A;  3GPN A;  2ZVL A;  2IO4 B;  2IX2 B;  3V61 B;  1RWZ A;  2HIK A;  2ZVW A;  1B8H A;  3U5Z F;  2OD8 A;  2AVT A;  5AUJ A;  2HII C;  3P87 A;  2IO4 A;  2IX2 A;  3P83 A;  5DAI A;  4RJF A;  3GPM A;  3FDS D;  2IJX A;  2ZVV A;  5E0V A;  1PLR A;  2NTI C;  2HII B;  3I2M X;  1UL1 A;  3U60 F;  3GGR C;  4TR6 A;  1RXZ A;  1UD9 A;  3F1W A;  3A2F B;  1VYM A;  1IZ5 A;  3P91 A;  1YYP A;  5E0U A;  2HII A;  1AXC A;  2NTI B;  3G65 C;  3GGR B;  2ZVK A;  5A6D A;  1DML A;  3VKX A;  5IY4 A;  3HSL X;  3A1J C;  4D2G A;  1SXJ F;  2NTI A;  3LX2 A;  5IXA A;  3FDS C;  1GE8 A;  4CS5 A;  3GGR A;  3G65 B;  1IZ4 A;  1U76 A;  5E0T A;  5JNE D;  1VYJ A;  3V60 B;  4ZTD A;  1T6L A;  4L6P A;  3A1J B;  2AWA A;  1ISQ A;  3G65 A;  3IFV A;  4L60 A;  3K4X A;  3AIZ C;  1W60 A;  3HI8 A;  1PLQ A;  3AIX B;  5DA7 A;  2Z0L A;  2ZVM A;  3A1J A;  3TBL A;  1U7B A;  3V62 B;  1RXM A;  2IZO B;  3LX1 A;  2HIK C;  3U61 F;  5CFK A;  5IWD A;  4YHR A;  3AIX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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