1RXZA

C-terminal region of a. fulgidus fen-1 complexed with a. fulgidus pcna
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
245
structure length
245
Chain Sequence
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
pubmed doi rcsb
molecule tags Replication
source organism Archaeoglobus fulgidus
molecule keywords DNA polymerase sliding clamp
total genus 56
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2003-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1rxzA00
3V61B 3P87A 2IO4B 4CS5A 3GGRA 3I2MX 5IY4A 2NTIC 3GPMA 1UD9A 2HIKA 3AIZC 4L6PA 5DAIA 3G65C 1DMLA 1RWZA 5CFKA 3GGRB 1U76A 2ZVVA 3A1JC 4YHRA 4HK1A 5AUJA 3V60B 1CZDA 2AWAA 3VKXA 2HIKB 2HIIA 3WGWA 3U61F 3IFVA 2IX2A 2ZVMA 3K4XA 5IXAA 3AIXA 1RXZA 4RJFA 3FDSD 1YYPA 3FDSC 5E0UA 3F1WA 1SXJF 5HACA 2OD8A 2ZVKA 5DA7A 4D2GA 1VYMA 1PLQA 2IZOB 2HIIB 1RXMA 2Z0LA 2IX2B 3GGRC 3P83A 4TR6A 3AIXB 2NTIA 3GPNA 1GE8A 5B7OA 2ZVWA 5E0VA 2AVTA 5JNED 3AIZA 2ZVLA 1IZ4A 3LX2A 5A6DA 3G65A 3A1JB 1IZ5A 2HIKC 3V62B 3HSLX 3A2FB 2NTIB 3A1JA 1ISQA 5IWDA 1AXCA 1B8HA 3TBLA 1W60A 1VYJA 3U5ZF 4L60A 1UL1A 2IO4A 3G65B 2IJXA 3HI8A 2IZOC 2HIIC 1PLRA 3LX1A 2IX2C 3P91A 4ZTDA 1T6LA 5H0TA 3U60F 1B77A 1U7BA 5E0TA
chains in the Genus database with same CATH superfamily
3V61B 3P87A 2IO4B 4CS5A 3GGRA 3I2MX 5IY4A 2NTIC 3GPMA 1UD9A 2HIKA 3AIZC 4L6PA 5DAIA 3G65C 1DMLA 1RWZA 5CFKA 3GGRB 1U76A 2ZVVA 3A1JC 4YHRA 4HK1A 5AUJA 3V60B 1CZDA 2AWAA 3VKXA 2HIKB 2HIIA 3WGWA 3U61F 3IFVA 2IX2A 2ZVMA 3K4XA 5IXAA 3AIXA 1RXZA 4RJFA 3FDSD 1YYPA 3FDSC 5E0UA 3F1WA 1SXJF 5HACA 2OD8A 2ZVKA 5DA7A 4D2GA 1VYMA 1PLQA 2IZOB 2HIIB 1RXMA 2Z0LA 2IX2B 3GGRC 3P83A 4TR6A 3AIXB 2NTIA 3GPNA 1GE8A 5B7OA 2ZVWA 5E0VA 2AVTA 5JNED 3AIZA 2ZVLA 1IZ4A 3LX2A 5A6DA 3G65A 3A1JB 1IZ5A 2HIKC 3V62B 3HSLX 3A2FB 2NTIB 3A1JA 1ISQA 5IWDA 1AXCA 1B8HA 3TBLA 1W60A 1VYJA 3U5ZF 4L60A 1UL1A 2IO4A 3G65B 2IJXA 3HI8A 2IZOC 2HIIC 1PLRA 3LX1A 2IX2C 3P91A 4ZTDA 1T6LA 5H0TA 3U60F 1B77A 1U7BA 5E0TA
chains in the Genus database with same CATH topology
3V61B 3P87A 2IO4B 4CS5A 3GGRA 3I2MX 5IY4A 2NTIC 3GPMA 1UD9A 2HIKA 3AIZC 4L6PA 5DAIA 3G65C 1DMLA 1RWZA 5CFKA 3GGRB 1U76A 2ZVVA 3A1JC 4YHRA 4HK1A 5AUJA 3V60B 1CZDA 2AWAA 3VKXA 2HIKB 2HIIA 3WGWA 3U61F 3IFVA 2IX2A 2ZVMA 3K4XA 5IXAA 3AIXA 1RXZA 4RJFA 3FDSD 1YYPA 3FDSC 5E0UA 3F1WA 1SXJF 5HACA 2OD8A 2ZVKA 5DA7A 4D2GA 1VYMA 1PLQA 2IZOB 2HIIB 1RXMA 2Z0LA 2IX2B 3GGRC 3P83A 4TR6A 3AIXB 2NTIA 3GPNA 1GE8A 5B7OA 2ZVWA 5E0VA 2AVTA 5JNED 3AIZA 2ZVLA 1IZ4A 3LX2A 5A6DA 3G65A 3A1JB 1IZ5A 2HIKC 3V62B 3HSLX 3A2FB 2NTIB 3A1JA 1ISQA 5IWDA 1AXCA 1B8HA 3TBLA 1W60A 1VYJA 3U5ZF 4L60A 1UL1A 2IO4A 3G65B 2IJXA 3HI8A 2IZOC 2HIIC 1PLRA 3LX1A 2IX2C 3P91A 4ZTDA 1T6LA 5H0TA 3U60F 1B77A 1U7BA 5E0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V61 B;  3P87 A;  2IO4 B;  4CS5 A;  3GGR A;  3I2M X;  5IY4 A;  2NTI C;  3GPM A;  1UD9 A;  2HIK A;  3AIZ C;  4L6P A;  5DAI A;  3G65 C;  1DML A;  1RWZ A;  5CFK A;  3GGR B;  1U76 A;  2ZVV A;  3A1J C;  4YHR A;  4HK1 A;  5AUJ A;  3V60 B;  1CZD A;  2AWA A;  3VKX A;  2HIK B;  2HII A;  3WGW A;  3U61 F;  3IFV A;  2IX2 A;  2ZVM A;  3K4X A;  5IXA A;  3AIX A;  1RXZ A;  4RJF A;  3FDS D;  1YYP A;  3FDS C;  5E0U A;  3F1W A;  1SXJ F;  5HAC A;  2OD8 A;  2ZVK A;  5DA7 A;  4D2G A;  1VYM A;  1PLQ A;  2IZO B;  2HII B;  1RXM A;  2Z0L A;  2IX2 B;  3GGR C;  3P83 A;  4TR6 A;  3AIX B;  2NTI A;  3GPN A;  1GE8 A;  5B7O A;  2ZVW A;  5E0V A;  2AVT A;  5JNE D;  3AIZ A;  2ZVL A;  1IZ4 A;  3LX2 A;  5A6D A;  3G65 A;  3A1J B;  1IZ5 A;  2HIK C;  3V62 B;  3HSL X;  3A2F B;  2NTI B;  3A1J A;  1ISQ A;  5IWD A;  1AXC A;  1B8H A;  3TBL A;  1W60 A;  1VYJ A;  3U5Z F;  4L60 A;  1UL1 A;  2IO4 A;  3G65 B;  2IJX A;  3HI8 A;  2IZO C;  2HII C;  1PLR A;  3LX1 A;  2IX2 C;  3P91 A;  4ZTD A;  1T6L A;  5H0T A;  3U60 F;  1B77 A;  1U7B A;  5E0T A; 
#chains in the Genus database with same CATH topology
 3V61 B;  3P87 A;  2IO4 B;  4CS5 A;  3GGR A;  3I2M X;  5IY4 A;  2NTI C;  3GPM A;  1UD9 A;  2HIK A;  3AIZ C;  4L6P A;  5DAI A;  3G65 C;  1DML A;  1RWZ A;  5CFK A;  3GGR B;  1U76 A;  2ZVV A;  3A1J C;  4YHR A;  4HK1 A;  5AUJ A;  3V60 B;  1CZD A;  2AWA A;  3VKX A;  2HIK B;  2HII A;  3WGW A;  3U61 F;  3IFV A;  2IX2 A;  2ZVM A;  3K4X A;  5IXA A;  3AIX A;  1RXZ A;  4RJF A;  3FDS D;  1YYP A;  3FDS C;  5E0U A;  3F1W A;  1SXJ F;  5HAC A;  2OD8 A;  2ZVK A;  5DA7 A;  4D2G A;  1VYM A;  1PLQ A;  2IZO B;  2HII B;  1RXM A;  2Z0L A;  2IX2 B;  3GGR C;  3P83 A;  4TR6 A;  3AIX B;  2NTI A;  3GPN A;  1GE8 A;  5B7O A;  2ZVW A;  5E0V A;  2AVT A;  5JNE D;  3AIZ A;  2ZVL A;  1IZ4 A;  3LX2 A;  5A6D A;  3G65 A;  3A1J B;  1IZ5 A;  2HIK C;  3V62 B;  3HSL X;  3A2F B;  2NTI B;  3A1J A;  1ISQ A;  5IWD A;  1AXC A;  1B8H A;  3TBL A;  1W60 A;  1VYJ A;  3U5Z F;  4L60 A;  1UL1 A;  2IO4 A;  3G65 B;  2IJX A;  3HI8 A;  2IZO C;  2HII C;  1PLR A;  3LX1 A;  2IX2 C;  3P91 A;  4ZTD A;  1T6L A;  5H0T A;  3U60 F;  1B77 A;  1U7B A;  5E0T A; 
#chains in the Genus database with same CATH homology
 3V61 B;  3P87 A;  2IO4 B;  4CS5 A;  3GGR A;  3I2M X;  5IY4 A;  2NTI C;  3GPM A;  1UD9 A;  2HIK A;  3AIZ C;  4L6P A;  5DAI A;  3G65 C;  1DML A;  1RWZ A;  5CFK A;  3GGR B;  1U76 A;  2ZVV A;  3A1J C;  4YHR A;  4HK1 A;  5AUJ A;  3V60 B;  1CZD A;  2AWA A;  3VKX A;  2HIK B;  2HII A;  3WGW A;  3U61 F;  3IFV A;  2IX2 A;  2ZVM A;  3K4X A;  5IXA A;  3AIX A;  1RXZ A;  4RJF A;  3FDS D;  1YYP A;  3FDS C;  5E0U A;  3F1W A;  1SXJ F;  5HAC A;  2OD8 A;  2ZVK A;  5DA7 A;  4D2G A;  1VYM A;  1PLQ A;  2IZO B;  2HII B;  1RXM A;  2Z0L A;  2IX2 B;  3GGR C;  3P83 A;  4TR6 A;  3AIX B;  2NTI A;  3GPN A;  1GE8 A;  5B7O A;  2ZVW A;  5E0V A;  2AVT A;  5JNE D;  3AIZ A;  2ZVL A;  1IZ4 A;  3LX2 A;  5A6D A;  3G65 A;  3A1J B;  1IZ5 A;  2HIK C;  3V62 B;  3HSL X;  3A2F B;  2NTI B;  3A1J A;  1ISQ A;  5IWD A;  1AXC A;  1B8H A;  3TBL A;  1W60 A;  1VYJ A;  3U5Z F;  4L60 A;  1UL1 A;  2IO4 A;  3G65 B;  2IJX A;  3HI8 A;  2IZO C;  2HII C;  1PLR A;  3LX1 A;  2IX2 C;  3P91 A;  4ZTD A;  1T6L A;  5H0T A;  3U60 F;  1B77 A;  1U7B A;  5E0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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