1T2RA

Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
123
structure length
123
Chain Sequence
GAMAMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
pubmed doi rcsb
molecule tags Nucleic acid binding protein/rna
source organism Drosophila melanogaster
molecule keywords 5'-R(*CP*UP*CP*AP*C)-3'
total genus 26
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2004-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1t2rA00
4Z4CA 4Z4GA 4NHAA 4W5RA 3MJ0A 1R6ZA 4Z4FA 4NGDA 1T2SA 2QVWA 5T7BA 3O7XA 4Z4HA 4F3TA 3QIRA 4KRFA 4W5TA 2L5DA 3O7VX 4NGCA 4KREA 4NH3A 4Z4EA 2FFLA 1VYNA 1SI3A 4OLAA 5JS1A 1R4KA 2L5CA 5KI6A 4OLBA 4W5OA 3O6EX 4NH5A 4NH6A 3O3IX 4NGBA 1T2RA 2XFMA 4W5NA 4NGFA 4W5QA 5JS2A 4Z4IA 1SI2A 4NGGA
chains in the Genus database with same CATH superfamily
4Z4CA 3HJFA 4Z4GA 4NHAA 4W5RA 3MJ0A 1R6ZA 3DLBA 3U1UA 1Z26A 3DA5A 4Z4FA 4NGDA 1SI2A 1T2SA 2BZEA 3HK2A 2QVWA 5T7BA 3O7XA 4Z4HA 4F3TA 3QIRA 4KRFA 4W5TA 4L1PA 2L5DA 3O7VX 4NGCA 4KREA 4NH3A 4Z4EA 2FFLA 1VYNA 3F73A 1SI3A 3HO1A 1Z25A 4OLAA 5JS1A 1R4KA 2L5CA 5KI6A 4OLBA 4W5OA 3O6EX 3DLHA 4NH5A 4NH6A 2DB9A 3O3IX 4NGBA 1T2RA 3HVRA 2XFMA 4W5NA 1U04A 4NGFA 4W5QA 5JS2A 4Z4IA 4L1UA 3HM9A 4NGGA
chains in the Genus database with same CATH topology
4Z4CA 3HJFA 4Z4GA 4NHAA 4W5RA 3MJ0A 1R6ZA 3DLBA 3U1UA 1Z26A 3DA5A 4Z4FA 4NGDA 1SI2A 1T2SA 2BZEA 3HK2A 2QVWA 5T7BA 3O7XA 4Z4HA 4F3TA 3QIRA 4KRFA 4W5TA 4L1PA 2L5DA 3O7VX 4NGCA 4KREA 4NH3A 4Z4EA 2FFLA 1VYNA 3F73A 1SI3A 3HO1A 1Z25A 4OLAA 5JS1A 1R4KA 2L5CA 5KI6A 4OLBA 4W5OA 3O6EX 3DLHA 4NH5A 4NH6A 2DB9A 3O3IX 4NGBA 1T2RA 3HVRA 2XFMA 4W5NA 1U04A 4NGFA 4W5QA 5JS2A 4Z4IA 4L1UA 3HM9A 4NGGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z4C A;  4Z4G A;  4NHA A;  4W5R A;  3MJ0 A;  1R6Z A;  4Z4F A;  4NGD A;  1T2S A;  2QVW A;  5T7B A;  3O7X A;  4Z4H A;  4F3T A;  3QIR A;  4KRF A;  4W5T A;  2L5D A;  3O7V X;  4NGC A;  4KRE A;  4NH3 A;  4Z4E A;  2FFL A;  1VYN A;  1SI3 A;  4OLA A;  5JS1 A;  1R4K A;  2L5C A;  5KI6 A;  4OLB A;  4W5O A;  3O6E X;  4NH5 A;  4NH6 A;  3O3I X;  4NGB A;  1T2R A;  2XFM A;  4W5N A;  4NGF A;  4W5Q A;  5JS2 A;  4Z4I A;  1SI2 A;  4NGG A; 
#chains in the Genus database with same CATH topology
 4Z4C A;  3HJF A;  4Z4G A;  4NHA A;  4W5R A;  3MJ0 A;  1R6Z A;  3DLB A;  3U1U A;  1Z26 A;  3DA5 A;  4Z4F A;  4NGD A;  1SI2 A;  1T2S A;  2BZE A;  3HK2 A;  2QVW A;  5T7B A;  3O7X A;  4Z4H A;  4F3T A;  3QIR A;  4KRF A;  4W5T A;  4L1P A;  2L5D A;  3O7V X;  4NGC A;  4KRE A;  4NH3 A;  4Z4E A;  2FFL A;  1VYN A;  3F73 A;  1SI3 A;  3HO1 A;  1Z25 A;  4OLA A;  5JS1 A;  1R4K A;  2L5C A;  5KI6 A;  4OLB A;  4W5O A;  3O6E X;  3DLH A;  4NH5 A;  4NH6 A;  2DB9 A;  3O3I X;  4NGB A;  1T2R A;  3HVR A;  2XFM A;  4W5N A;  1U04 A;  4NGF A;  4W5Q A;  5JS2 A;  4Z4I A;  4L1U A;  3HM9 A;  4NGG A; 
#chains in the Genus database with same CATH homology
 4Z4C A;  3HJF A;  4Z4G A;  4NHA A;  4W5R A;  3MJ0 A;  1R6Z A;  3DLB A;  3U1U A;  1Z26 A;  3DA5 A;  4Z4F A;  4NGD A;  1SI2 A;  1T2S A;  2BZE A;  3HK2 A;  2QVW A;  5T7B A;  3O7X A;  4Z4H A;  4F3T A;  3QIR A;  4KRF A;  4W5T A;  4L1P A;  2L5D A;  3O7V X;  4NGC A;  4KRE A;  4NH3 A;  4Z4E A;  2FFL A;  1VYN A;  3F73 A;  1SI3 A;  3HO1 A;  1Z25 A;  4OLA A;  5JS1 A;  1R4K A;  2L5C A;  5KI6 A;  4OLB A;  4W5O A;  3O6E X;  3DLH A;  4NH5 A;  4NH6 A;  2DB9 A;  3O3I X;  4NGB A;  1T2R A;  3HVR A;  2XFM A;  4W5N A;  1U04 A;  4NGF A;  4W5Q A;  5JS2 A;  4Z4I A;  4L1U A;  3HM9 A;  4NGG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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