1T2SA

Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
123
structure length
123
Chain Sequence
GAMAMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
pubmed doi rcsb
molecule tags Nucleic acid binding protein/dna
source organism Drosophila melanogaster
molecule keywords 5'-D(*CP*TP*CP*AP*C)-3'
total genus 22
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2004-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1t2sA00
4OLAA 4W5QA 3O7VX 4NH5A 1T2RA 3O6EX 1SI2A 4W5NA 3O7XA 4Z4FA 4KREA 5T7BA 4W5TA 4Z4IA 4OLBA 4NGGA 2QVWA 4KRFA 2FFLA 4NHAA 3O3IX 4NH6A 3MJ0A 4W5RA 2L5CA 4Z4EA 4Z4GA 1R6ZA 4Z4HA 4NGFA 1SI3A 4NGDA 4W5OA 1VYNA 5KI6A 4NGBA 4Z4CA 2L5DA 5JS1A 4NGCA 4NH3A 5JS2A 1R4KA 4F3TA 1T2SA 2XFMA 3QIRA
chains in the Genus database with same CATH superfamily
4L1PA 4OLAA 4W5QA 3O7VX 4NH5A 1T2RA 3O6EX 1SI2A 4W5NA 3DA5A 3O7XA 4Z4FA 4KREA 3HVRA 5T7BA 4W5TA 4Z4IA 4OLBA 4NGGA 1Z25A 3HM9A 2QVWA 2DB9A 2BZEA 4KRFA 2FFLA 3U1UA 4NHAA 3O3IX 4NH6A 1U04A 3MJ0A 4W5RA 3HJFA 4L1UA 2L5CA 4Z4EA 4Z4GA 1R6ZA 4Z4HA 4NGFA 1SI3A 3HO1A 4W5OA 1VYNA 4NGDA 5KI6A 4NGBA 4Z4CA 1Z26A 2L5DA 3DLHA 3HK2A 5JS1A 4NGCA 4NH3A 3F73A 5JS2A 3DLBA 1R4KA 4F3TA 1T2SA 2XFMA 3QIRA
chains in the Genus database with same CATH topology
4L1PA 4OLAA 4W5QA 3O7VX 4NH5A 1T2RA 3O6EX 1SI2A 4W5NA 3DA5A 3O7XA 4Z4FA 4KREA 3HVRA 5T7BA 4W5TA 4Z4IA 4OLBA 4NGGA 1Z25A 3HM9A 2QVWA 2DB9A 2BZEA 4KRFA 2FFLA 3U1UA 4NHAA 3O3IX 4NH6A 1U04A 3MJ0A 4W5RA 3HJFA 4L1UA 2L5CA 4Z4EA 4Z4GA 1R6ZA 4Z4HA 4NGFA 1SI3A 3HO1A 4W5OA 1VYNA 4NGDA 5KI6A 4NGBA 4Z4CA 1Z26A 2L5DA 3DLHA 3HK2A 5JS1A 4NGCA 4NH3A 3F73A 5JS2A 3DLBA 1R4KA 4F3TA 1T2SA 2XFMA 3QIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OLA A;  4W5Q A;  3O7V X;  4NH5 A;  1T2R A;  3O6E X;  1SI2 A;  4W5N A;  3O7X A;  4Z4F A;  4KRE A;  5T7B A;  4W5T A;  4Z4I A;  4OLB A;  4NGG A;  2QVW A;  4KRF A;  2FFL A;  4NHA A;  3O3I X;  4NH6 A;  3MJ0 A;  4W5R A;  2L5C A;  4Z4E A;  4Z4G A;  1R6Z A;  4Z4H A;  4NGF A;  1SI3 A;  4NGD A;  4W5O A;  1VYN A;  5KI6 A;  4NGB A;  4Z4C A;  2L5D A;  5JS1 A;  4NGC A;  4NH3 A;  5JS2 A;  1R4K A;  4F3T A;  1T2S A;  2XFM A;  3QIR A; 
#chains in the Genus database with same CATH topology
 4L1P A;  4OLA A;  4W5Q A;  3O7V X;  4NH5 A;  1T2R A;  3O6E X;  1SI2 A;  4W5N A;  3DA5 A;  3O7X A;  4Z4F A;  4KRE A;  3HVR A;  5T7B A;  4W5T A;  4Z4I A;  4OLB A;  4NGG A;  1Z25 A;  3HM9 A;  2QVW A;  2DB9 A;  2BZE A;  4KRF A;  2FFL A;  3U1U A;  4NHA A;  3O3I X;  4NH6 A;  1U04 A;  3MJ0 A;  4W5R A;  3HJF A;  4L1U A;  2L5C A;  4Z4E A;  4Z4G A;  1R6Z A;  4Z4H A;  4NGF A;  1SI3 A;  3HO1 A;  4W5O A;  1VYN A;  4NGD A;  5KI6 A;  4NGB A;  4Z4C A;  1Z26 A;  2L5D A;  3DLH A;  3HK2 A;  5JS1 A;  4NGC A;  4NH3 A;  3F73 A;  5JS2 A;  3DLB A;  1R4K A;  4F3T A;  1T2S A;  2XFM A;  3QIR A; 
#chains in the Genus database with same CATH homology
 4L1P A;  4OLA A;  4W5Q A;  3O7V X;  4NH5 A;  1T2R A;  3O6E X;  1SI2 A;  4W5N A;  3DA5 A;  3O7X A;  4Z4F A;  4KRE A;  3HVR A;  5T7B A;  4W5T A;  4Z4I A;  4OLB A;  4NGG A;  1Z25 A;  3HM9 A;  2QVW A;  2DB9 A;  2BZE A;  4KRF A;  2FFL A;  3U1U A;  4NHA A;  3O3I X;  4NH6 A;  1U04 A;  3MJ0 A;  4W5R A;  3HJF A;  4L1U A;  2L5C A;  4Z4E A;  4Z4G A;  1R6Z A;  4Z4H A;  4NGF A;  1SI3 A;  3HO1 A;  4W5O A;  1VYN A;  4NGD A;  5KI6 A;  4NGB A;  4Z4C A;  1Z26 A;  2L5D A;  3DLH A;  3HK2 A;  5JS1 A;  4NGC A;  4NH3 A;  3F73 A;  5JS2 A;  3DLB A;  1R4K A;  4F3T A;  1T2S A;  2XFM A;  3QIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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