2A11A

Crystal structure of nuclease domain of ribonuclase iii from mycobacterium tuberculosis
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
154
structure length
154
Chain Sequence
IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A
pubmed doi rcsb
molecule tags Transcription,translation,hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Ribonuclease III
total genus 57
structure length 154
sequence length 154
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2005-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00035 dsrm Double-stranded RNA binding motif
A PF14622 Ribonucleas_3_3 Ribonuclease-III-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1520.10 Mainly Alpha Orthogonal Bundle Ribonuclease iii, N-terminal Endonuclease Domain; Chain A Ribonuclease III domain 2a11A00
3O2RB 4M30A 3C4TA 4OUNA 3O2RA 4M2ZA 1U61A 2QVWA 1YYKA 2NUGA 2EB1A 1YZ9A 2EZ6A 1RC7A 1JFZA 2A11A 1O0WA 1YYOA 1YYWA 3C4BA 4OOGC 3RV0A 3RV1A 3N3WA 2NUEA 2GSLA 2FFLA 2NUFA 1I4SA 1RC5A
chains in the Genus database with same CATH superfamily
3O2RB 4M30A 1ZTDA 3C4TA 4OUNA 3O2RA 4M2ZA 1U61A 2QVWA 1YYKA 2NUGA 2EB1A 1YZ9A 2EZ6A 1RC7A 1JFZA 2A11A 1O0WA 1YYOA 1YYWA 3C4BA 4OOGC 3RV0A 3RV1A 3N3WA 2NUEA 2GSLA 2FFLA 2NUFA 1I4SA 1RC5A
chains in the Genus database with same CATH topology
3O2RB 4M30A 3C4TA 4OUNA 3O2RA 4M2ZA 1U61A 2QVWA 1YYKA 2NUGA 2EB1A 1YZ9A 2EZ6A 1RC7A 1JFZA 2A11A 1O0WA 1YYOA 1YYWA 3C4BA 4OOGC 3RV0A 3RV1A 3N3WA 2NUEA 2GSLA 2FFLA 2NUFA 1I4SA 1RC5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O2R B;  4M30 A;  3C4T A;  4OUN A;  3O2R A;  4M2Z A;  1U61 A;  2QVW A;  1YYK A;  2NUG A;  2EB1 A;  1YZ9 A;  2EZ6 A;  1RC7 A;  1JFZ A;  2A11 A;  1O0W A;  1YYO A;  1YYW A;  3C4B A;  4OOG C;  3RV0 A;  3RV1 A;  3N3W A;  2NUE A;  2GSL A;  2FFL A;  2NUF A;  1I4S A;  1RC5 A; 
#chains in the Genus database with same CATH topology
 3O2R B;  4M30 A;  1ZTD A;  3C4T A;  4OUN A;  3O2R A;  4M2Z A;  1U61 A;  2QVW A;  1YYK A;  2NUG A;  2EB1 A;  1YZ9 A;  2EZ6 A;  1RC7 A;  1JFZ A;  2A11 A;  1O0W A;  1YYO A;  1YYW A;  3C4B A;  4OOG C;  3RV0 A;  3RV1 A;  3N3W A;  2NUE A;  2GSL A;  2FFL A;  2NUF A;  1I4S A;  1RC5 A; 
#chains in the Genus database with same CATH homology
 3O2R B;  4M30 A;  3C4T A;  4OUN A;  3O2R A;  4M2Z A;  1U61 A;  2QVW A;  1YYK A;  2NUG A;  2EB1 A;  1YZ9 A;  2EZ6 A;  1RC7 A;  1JFZ A;  2A11 A;  1O0W A;  1YYO A;  1YYW A;  3C4B A;  4OOG C;  3RV0 A;  3RV1 A;  3N3W A;  2NUE A;  2GSL A;  2FFL A;  2NUF A;  1I4S A;  1RC5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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