2IO4A

Crystal structure of pcna12 dimer from sulfolobus solfataricus.
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
249
structure length
249
Chain Sequence
MVKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYSIDSPTSVKLDVSSVKKILSKASSKKATIELTETDSGLKIIIRDEKSGAKSTIYIKAEKGQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEAGEEGKRYVAFLMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGHMIFWIAPRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Sulfolobus solfataricus
molecule keywords DNA polymerase sliding clamp B
total genus 61
structure length 249
sequence length 249
chains with identical sequence C
ec nomenclature
pdb deposition date 2006-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2io4A01
2NTIB 2HIIB 1B8HA 3LX2A 1SXJF 1RXMA 2AVTA 3A1JB 2HIIA 1AXCA 5H0TA 3GGRB 4L60A 1PLQA 2IZOB 5B7OA 4YHRA 1UL1A 3I2MX 3GGRA 2IJXA 1T6LA 1ISQA 2ZVVA 1RXZA 3WGWA 3G65C 2ZVLA 1W60A 5JNED 3LX1A 4L6PA 1RWZA 3HSLX 2NTIA 3V60B 1U76A 2HIKC 5E0VA 3F1WA 1DMLA 4ZTDA 3AIZC 3A1JA 3P87A 2IX2C 3VKXA 1YYPA 3U61F 2AWAA 1VYJA 3FDSD 1UD9A 2OD8A 3U60F 3GPNA 5E0TA 5AUJA 5CFKA 5DAIA 5IWDA 1PLRA 2ZVWA 3G65B 3TBLA 3V61B 3IFVA 1VYMA 4RJFA 3G65A 5HACA 2HIKB 2NTIC 1U7BA 2HIIC 1B77A 3AIXB 2IX2B 2HIKA 3U5ZF 5IXAA 2ZVKA 5IY4A 3A1JC 1CZDA 3AIZA 3AIXA 1GE8A 2IX2A 3GGRC 3V62B 2IZOC 2IO4B 2Z0LA 3HI8A 2ZVMA 4HK1A 1IZ4A 5E0UA 5DA7A 1IZ5A 4D2GA 2IO4A 3A2FB 4CS5A 3K4XA 3FDSC 3P83A 4TR6A 5A6DA 3P91A 3GPMA
chains in the Genus database with same CATH superfamily
2NTIB 2HIIB 1B8HA 3LX2A 1SXJF 1RXMA 2AVTA 3A1JB 2HIIA 1AXCA 5H0TA 3GGRB 4L60A 1PLQA 2IZOB 5B7OA 4YHRA 1UL1A 3I2MX 3GGRA 2IJXA 1T6LA 1ISQA 2ZVVA 1RXZA 3WGWA 3G65C 2ZVLA 1W60A 5JNED 3LX1A 4L6PA 1RWZA 3HSLX 2NTIA 3V60B 1U76A 2HIKC 5E0VA 3F1WA 1DMLA 4ZTDA 3AIZC 3A1JA 3P87A 2IX2C 3VKXA 1YYPA 3U61F 2AWAA 1VYJA 3FDSD 1UD9A 2OD8A 3U60F 3GPNA 5E0TA 5AUJA 5CFKA 5DAIA 5IWDA 1PLRA 2ZVWA 3G65B 3TBLA 3V61B 3IFVA 1VYMA 4RJFA 3G65A 5HACA 2HIKB 2NTIC 1U7BA 2HIIC 1B77A 3AIXB 2IX2B 2HIKA 3U5ZF 5IXAA 2ZVKA 5IY4A 3A1JC 1CZDA 3AIZA 3AIXA 1GE8A 2IX2A 3GGRC 3V62B 2IZOC 2IO4B 2Z0LA 3HI8A 2ZVMA 4HK1A 1IZ4A 5E0UA 5DA7A 1IZ5A 4D2GA 2IO4A 3A2FB 4CS5A 3K4XA 3FDSC 3P83A 4TR6A 5A6DA 3P91A 3GPMA
chains in the Genus database with same CATH topology
2NTIB 2HIIB 1B8HA 3LX2A 1SXJF 1RXMA 2AVTA 3A1JB 2HIIA 1AXCA 5H0TA 3GGRB 4L60A 1PLQA 2IZOB 5B7OA 4YHRA 1UL1A 3I2MX 3GGRA 2IJXA 1T6LA 1ISQA 2ZVVA 1RXZA 3WGWA 3G65C 2ZVLA 1W60A 5JNED 3LX1A 4L6PA 1RWZA 3HSLX 2NTIA 3V60B 1U76A 2HIKC 5E0VA 3F1WA 1DMLA 4ZTDA 3AIZC 3A1JA 3P87A 2IX2C 3VKXA 1YYPA 3U61F 2AWAA 1VYJA 3FDSD 1UD9A 2OD8A 3U60F 3GPNA 5E0TA 5AUJA 5CFKA 5DAIA 5IWDA 1PLRA 2ZVWA 3G65B 3TBLA 3V61B 3IFVA 1VYMA 4RJFA 3G65A 5HACA 2HIKB 2NTIC 1U7BA 2HIIC 1B77A 3AIXB 2IX2B 2HIKA 3U5ZF 5IXAA 2ZVKA 5IY4A 3A1JC 1CZDA 3AIZA 3AIXA 1GE8A 2IX2A 3GGRC 3V62B 2IZOC 2IO4B 2Z0LA 3HI8A 2ZVMA 4HK1A 1IZ4A 5E0UA 5DA7A 1IZ5A 4D2GA 2IO4A 3A2FB 4CS5A 3K4XA 3FDSC 3P83A 4TR6A 5A6DA 3P91A 3GPMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NTI B;  2HII B;  1B8H A;  3LX2 A;  1SXJ F;  1RXM A;  2AVT A;  3A1J B;  2HII A;  1AXC A;  5H0T A;  3GGR B;  4L60 A;  1PLQ A;  2IZO B;  5B7O A;  4YHR A;  1UL1 A;  3I2M X;  3GGR A;  2IJX A;  1T6L A;  1ISQ A;  2ZVV A;  1RXZ A;  3WGW A;  3G65 C;  2ZVL A;  1W60 A;  5JNE D;  3LX1 A;  4L6P A;  1RWZ A;  3HSL X;  2NTI A;  3V60 B;  1U76 A;  2HIK C;  5E0V A;  3F1W A;  1DML A;  4ZTD A;  3AIZ C;  3A1J A;  3P87 A;  2IX2 C;  3VKX A;  1YYP A;  3U61 F;  2AWA A;  1VYJ A;  3FDS D;  1UD9 A;  2OD8 A;  3U60 F;  3GPN A;  5E0T A;  5AUJ A;  5CFK A;  5DAI A;  5IWD A;  1PLR A;  2ZVW A;  3G65 B;  3TBL A;  3V61 B;  3IFV A;  1VYM A;  4RJF A;  3G65 A;  5HAC A;  2HIK B;  2NTI C;  1U7B A;  2HII C;  1B77 A;  3AIX B;  2IX2 B;  2HIK A;  3U5Z F;  5IXA A;  2ZVK A;  5IY4 A;  3A1J C;  1CZD A;  3AIZ A;  3AIX A;  1GE8 A;  2IX2 A;  3GGR C;  3V62 B;  2IZO C;  2IO4 B;  2Z0L A;  3HI8 A;  2ZVM A;  4HK1 A;  1IZ4 A;  5E0U A;  5DA7 A;  1IZ5 A;  4D2G A;  2IO4 A;  3A2F B;  4CS5 A;  3K4X A;  3FDS C;  3P83 A;  4TR6 A;  5A6D A;  3P91 A;  3GPM A; 
#chains in the Genus database with same CATH topology
 2NTI B;  2HII B;  1B8H A;  3LX2 A;  1SXJ F;  1RXM A;  2AVT A;  3A1J B;  2HII A;  1AXC A;  5H0T A;  3GGR B;  4L60 A;  1PLQ A;  2IZO B;  5B7O A;  4YHR A;  1UL1 A;  3I2M X;  3GGR A;  2IJX A;  1T6L A;  1ISQ A;  2ZVV A;  1RXZ A;  3WGW A;  3G65 C;  2ZVL A;  1W60 A;  5JNE D;  3LX1 A;  4L6P A;  1RWZ A;  3HSL X;  2NTI A;  3V60 B;  1U76 A;  2HIK C;  5E0V A;  3F1W A;  1DML A;  4ZTD A;  3AIZ C;  3A1J A;  3P87 A;  2IX2 C;  3VKX A;  1YYP A;  3U61 F;  2AWA A;  1VYJ A;  3FDS D;  1UD9 A;  2OD8 A;  3U60 F;  3GPN A;  5E0T A;  5AUJ A;  5CFK A;  5DAI A;  5IWD A;  1PLR A;  2ZVW A;  3G65 B;  3TBL A;  3V61 B;  3IFV A;  1VYM A;  4RJF A;  3G65 A;  5HAC A;  2HIK B;  2NTI C;  1U7B A;  2HII C;  1B77 A;  3AIX B;  2IX2 B;  2HIK A;  3U5Z F;  5IXA A;  2ZVK A;  5IY4 A;  3A1J C;  1CZD A;  3AIZ A;  3AIX A;  1GE8 A;  2IX2 A;  3GGR C;  3V62 B;  2IZO C;  2IO4 B;  2Z0L A;  3HI8 A;  2ZVM A;  4HK1 A;  1IZ4 A;  5E0U A;  5DA7 A;  1IZ5 A;  4D2G A;  2IO4 A;  3A2F B;  4CS5 A;  3K4X A;  3FDS C;  3P83 A;  4TR6 A;  5A6D A;  3P91 A;  3GPM A; 
#chains in the Genus database with same CATH homology
 2NTI B;  2HII B;  1B8H A;  3LX2 A;  1SXJ F;  1RXM A;  2AVT A;  3A1J B;  2HII A;  1AXC A;  5H0T A;  3GGR B;  4L60 A;  1PLQ A;  2IZO B;  5B7O A;  4YHR A;  1UL1 A;  3I2M X;  3GGR A;  2IJX A;  1T6L A;  1ISQ A;  2ZVV A;  1RXZ A;  3WGW A;  3G65 C;  2ZVL A;  1W60 A;  5JNE D;  3LX1 A;  4L6P A;  1RWZ A;  3HSL X;  2NTI A;  3V60 B;  1U76 A;  2HIK C;  5E0V A;  3F1W A;  1DML A;  4ZTD A;  3AIZ C;  3A1J A;  3P87 A;  2IX2 C;  3VKX A;  1YYP A;  3U61 F;  2AWA A;  1VYJ A;  3FDS D;  1UD9 A;  2OD8 A;  3U60 F;  3GPN A;  5E0T A;  5AUJ A;  5CFK A;  5DAI A;  5IWD A;  1PLR A;  2ZVW A;  3G65 B;  3TBL A;  3V61 B;  3IFV A;  1VYM A;  4RJF A;  3G65 A;  5HAC A;  2HIK B;  2NTI C;  1U7B A;  2HII C;  1B77 A;  3AIX B;  2IX2 B;  2HIK A;  3U5Z F;  5IXA A;  2ZVK A;  5IY4 A;  3A1J C;  1CZD A;  3AIZ A;  3AIX A;  1GE8 A;  2IX2 A;  3GGR C;  3V62 B;  2IZO C;  2IO4 B;  2Z0L A;  3HI8 A;  2ZVM A;  4HK1 A;  1IZ4 A;  5E0U A;  5DA7 A;  1IZ5 A;  4D2G A;  2IO4 A;  3A2F B;  4CS5 A;  3K4X A;  3FDS C;  3P83 A;  4TR6 A;  5A6D A;  3P91 A;  3GPM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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