2IZO | Genus

Total Genus 57

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	57
sequence length	244
structure length	244
Chain Sequence	MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDILKRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTSPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFYIAPR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Sulfolobus solfataricus
publication title	Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity. pubmed doi rcsb
molecule keywords	FLAP STRUCTURE-SPECIFIC ENDONUCLEASE
total genus	57
structure length	244
sequence length	244
ec nomenclature
pdb deposition date	2006-07-25

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00705	PCNA_N	Proliferating cell nuclear antigen, N-terminal domain
B	PF02747	PCNA_C	Proliferating cell nuclear antigen, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	2izoB00

3G65C 1B8HA 2IO4B 2NTIA 2Z0LA 2OD8A 1U76A 3A1JA 5IY4A 3VKXA 3HI8A 3HSLX 2HIIB 5A6DA 1RXZA 3IFVA 2NTIC 3A1JC 2IZOC 1GE8A 5E0UA 3TBLA 5CFKA 2ZVMA 3P83A 3V61B 2HIKC 4HK1A 4ZTDA 1ISQA 5DA7A 1VYJA 4D2GA 3P91A 2AWAA 2ZVLA 2ZVKA 2NTIB 2IX2A 2ZVWA 3A1JB 3I2MX 1T6LA 2IZOB 5B7OA 1YYPA 3V60B 3AIXA 4L6PA 1IZ5A 5AUJA 2IO4A 1U7BA 3AIZA 3FDSD 1IZ4A 5IXAA 3GGRA 2HIKB 3G65B 3U5ZF 5H0TA 2HIIA 3A2FB 5JNED 3LX2A 1UD9A 3U60F 1RWZA 3P87A 3GGRC 4L60A 4TR6A 1RXMA 5DAIA 3K4XA 5IWDA 1PLQA 3LX1A 1VYMA 3AIXB 3V62B 2AVTA 2IX2C 5HACA 1B77A 5E0VA 3GPMA 3F1WA 3GGRB 1SXJF 1DMLA 3AIZC 3GPNA 2IJXA 4YHRA 3FDSC 3WGWA 2HIKA 1UL1A 3G65A 1W60A 2HIIC 2ZVVA 5E0TA 1CZDA 4RJFA 1AXCA 2IX2B 1PLRA 3U61F 4CS5A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3G65 C;  1B8H A;  2IO4 B;  2NTI A;  2Z0L A;  2OD8 A;  1U76 A;  3A1J A;  5IY4 A;  3VKX A;  3HI8 A;  3HSL X;  2HII B;  5A6D A;  1RXZ A;  3IFV A;  2NTI C;  3A1J C;  2IZO C;  1GE8 A;  5E0U A;  3TBL A;  5CFK A;  2ZVM A;  3P83 A;  3V61 B;  2HIK C;  4HK1 A;  4ZTD A;  1ISQ A;  5DA7 A;  1VYJ A;  4D2G A;  3P91 A;  2AWA A;  2ZVL A;  2ZVK A;  2NTI B;  2IX2 A;  2ZVW A;  3A1J B;  3I2M X;  1T6L A;  2IZO B;  5B7O A;  1YYP A;  3V60 B;  3AIX A;  4L6P A;  1IZ5 A;  5AUJ A;  2IO4 A;  1U7B A;  3AIZ A;  3FDS D;  1IZ4 A;  5IXA A;  3GGR A;  2HIK B;  3G65 B;  3U5Z F;  5H0T A;  2HII A;  3A2F B;  5JNE D;  3LX2 A;  1UD9 A;  3U60 F;  1RWZ A;  3P87 A;  3GGR C;  4L60 A;  4TR6 A;  1RXM A;  5DAI A;  3K4X A;  5IWD A;  1PLQ A;  3LX1 A;  1VYM A;  3AIX B;  3V62 B;  2AVT A;  2IX2 C;  5HAC A;  1B77 A;  5E0V A;  3GPM A;  3F1W A;  3GGR B;  1SXJ F;  1DML A;  3AIZ C;  3GPN A;  2IJX A;  4YHR A;  3FDS C;  3WGW A;  2HIK A;  1UL1 A;  3G65 A;  1W60 A;  2HII C;  2ZVV A;  5E0T A;  1CZD A;  4RJF A;  1AXC A;  2IX2 B;  1PLR A;  3U61 F;  4CS5 A; 
#chains in the Genus database with same CATH topology
 3G65 C;  1B8H A;  2IO4 B;  2NTI A;  2Z0L A;  2OD8 A;  1U76 A;  3A1J A;  5IY4 A;  3VKX A;  3HI8 A;  3HSL X;  2HII B;  5A6D A;  1RXZ A;  3IFV A;  2NTI C;  3A1J C;  2IZO C;  1GE8 A;  5E0U A;  3TBL A;  5CFK A;  2ZVM A;  3P83 A;  3V61 B;  2HIK C;  4HK1 A;  4ZTD A;  1ISQ A;  5DA7 A;  1VYJ A;  4D2G A;  3P91 A;  2AWA A;  2ZVL A;  2ZVK A;  2NTI B;  2IX2 A;  2ZVW A;  3A1J B;  3I2M X;  1T6L A;  2IZO B;  5B7O A;  1YYP A;  3V60 B;  3AIX A;  4L6P A;  1IZ5 A;  5AUJ A;  2IO4 A;  1U7B A;  3AIZ A;  3FDS D;  1IZ4 A;  5IXA A;  3GGR A;  2HIK B;  3G65 B;  3U5Z F;  5H0T A;  2HII A;  3A2F B;  5JNE D;  3LX2 A;  1UD9 A;  3U60 F;  1RWZ A;  3P87 A;  3GGR C;  4L60 A;  4TR6 A;  1RXM A;  5DAI A;  3K4X A;  5IWD A;  1PLQ A;  3LX1 A;  1VYM A;  3AIX B;  3V62 B;  2AVT A;  2IX2 C;  5HAC A;  1B77 A;  5E0V A;  3GPM A;  3F1W A;  3GGR B;  1SXJ F;  1DML A;  3AIZ C;  3GPN A;  2IJX A;  4YHR A;  3FDS C;  3WGW A;  2HIK A;  1UL1 A;  3G65 A;  1W60 A;  2HII C;  2ZVV A;  5E0T A;  1CZD A;  4RJF A;  1AXC A;  2IX2 B;  1PLR A;  3U61 F;  4CS5 A; 
#chains in the Genus database with same CATH homology
 3G65 C;  1B8H A;  2IO4 B;  2NTI A;  2Z0L A;  2OD8 A;  1U76 A;  3A1J A;  5IY4 A;  3VKX A;  3HI8 A;  3HSL X;  2HII B;  5A6D A;  1RXZ A;  3IFV A;  2NTI C;  3A1J C;  2IZO C;  1GE8 A;  5E0U A;  3TBL A;  5CFK A;  2ZVM A;  3P83 A;  3V61 B;  2HIK C;  4HK1 A;  4ZTD A;  1ISQ A;  5DA7 A;  1VYJ A;  4D2G A;  3P91 A;  2AWA A;  2ZVL A;  2ZVK A;  2NTI B;  2IX2 A;  2ZVW A;  3A1J B;  3I2M X;  1T6L A;  2IZO B;  5B7O A;  1YYP A;  3V60 B;  3AIX A;  4L6P A;  1IZ5 A;  5AUJ A;  2IO4 A;  1U7B A;  3AIZ A;  3FDS D;  1IZ4 A;  5IXA A;  3GGR A;  2HIK B;  3G65 B;  3U5Z F;  5H0T A;  2HII A;  3A2F B;  5JNE D;  3LX2 A;  1UD9 A;  3U60 F;  1RWZ A;  3P87 A;  3GGR C;  4L60 A;  4TR6 A;  1RXM A;  5DAI A;  3K4X A;  5IWD A;  1PLQ A;  3LX1 A;  1VYM A;  3AIX B;  3V62 B;  2AVT A;  2IX2 C;  5HAC A;  1B77 A;  5E0V A;  3GPM A;  3F1W A;  3GGR B;  1SXJ F;  1DML A;  3AIZ C;  3GPN A;  2IJX A;  4YHR A;  3FDS C;  3WGW A;  2HIK A;  1UL1 A;  3G65 A;  1W60 A;  2HII C;  2ZVV A;  5E0T A;  1CZD A;  4RJF A;  1AXC A;  2IX2 B;  1PLR A;  3U61 F;  4CS5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2IZOB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations