2NTIB

Crystal structure of pcna123 heterotrimer.
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
245
structure length
245
Chain Sequence
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDILKRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFYIAPRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Sulfolobus solfataricus
molecule keywords DNA polymerase sliding clamp B
total genus 59
structure length 245
sequence length 245
chains with identical sequence E, H
ec nomenclature
pdb deposition date 2006-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
B PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2ntiB00
3VKXA 2IX2B 1RXZA 3GGRA 3IFVA 4RJFA 3GPNA 5IXAA 1SXJF 1IZ4A 4HK1A 1DMLA 1U7BA 2AWAA 3A2FB 3HI8A 5DA7A 5E0VA 2HIKC 2Z0LA 3U60F 1RWZA 5E0TA 3P91A 1CZDA 5AUJA 1UD9A 1U76A 5IY4A 1IZ5A 2IO4A 3G65B 3AIZA 3A1JB 4D2GA 3U5ZF 2IZOB 3V61B 2IO4B 3FDSC 1W60A 1VYMA 1VYJA 4CS5A 2NTIA 5H0TA 3GGRB 3LX2A 3HSLX 1UL1A 5DAIA 3K4XA 2HIIC 5JNED 3G65C 5HACA 3A1JC 2IX2C 2IZOC 2ZVLA 3I2MX 5B7OA 1B77A 3P83A 3P87A 2AVTA 4L60A 2HIKA 1GE8A 3GGRC 2ZVKA 5A6DA 2HIIA 5E0UA 4YHRA 2NTIB 4TR6A 1T6LA 3TBLA 3F1WA 5CFKA 3AIXA 3V62B 3LX1A 3GPMA 3AIXB 3AIZC 4L6PA 3U61F 4ZTDA 1B8HA 2ZVMA 1YYPA 2NTIC 2OD8A 3G65A 2HIKB 2IJXA 3V60B 3A1JA 2ZVVA 2IX2A 1PLQA 3WGWA 1RXMA 2ZVWA 3FDSD 2HIIB 1AXCA 1ISQA 5IWDA 1PLRA
chains in the Genus database with same CATH superfamily
3VKXA 2IX2B 1RXZA 3GGRA 3IFVA 4RJFA 3GPNA 5IXAA 1SXJF 1IZ4A 4HK1A 1DMLA 1U7BA 2AWAA 3A2FB 3HI8A 5DA7A 5E0VA 2HIKC 2Z0LA 3U60F 1RWZA 5E0TA 3P91A 1CZDA 5AUJA 1UD9A 1U76A 5IY4A 1IZ5A 2IO4A 3G65B 3AIZA 3A1JB 4D2GA 3U5ZF 2IZOB 3V61B 2IO4B 3FDSC 1W60A 1VYMA 1VYJA 4CS5A 2NTIA 5H0TA 3GGRB 3LX2A 3HSLX 1UL1A 5DAIA 3K4XA 2HIIC 5JNED 3G65C 5HACA 3A1JC 2IX2C 2IZOC 2ZVLA 3I2MX 5B7OA 1B77A 3P83A 3P87A 2AVTA 4L60A 2HIKA 1GE8A 3GGRC 2ZVKA 5A6DA 2HIIA 5E0UA 4YHRA 2NTIB 4TR6A 1T6LA 3TBLA 3F1WA 5CFKA 3AIXA 3V62B 3LX1A 3GPMA 3AIXB 3AIZC 4L6PA 3U61F 4ZTDA 1B8HA 2ZVMA 1YYPA 2NTIC 2OD8A 3G65A 2HIKB 2IJXA 3V60B 3A1JA 2ZVVA 2IX2A 1PLQA 3WGWA 1RXMA 2ZVWA 3FDSD 2HIIB 1AXCA 1ISQA 5IWDA 1PLRA
chains in the Genus database with same CATH topology
3VKXA 2IX2B 1RXZA 3GGRA 3IFVA 4RJFA 3GPNA 5IXAA 1SXJF 1IZ4A 4HK1A 1DMLA 1U7BA 2AWAA 3A2FB 3HI8A 5DA7A 5E0VA 2HIKC 2Z0LA 3U60F 1RWZA 5E0TA 3P91A 1CZDA 5AUJA 1UD9A 1U76A 5IY4A 1IZ5A 2IO4A 3G65B 3AIZA 3A1JB 4D2GA 3U5ZF 2IZOB 3V61B 2IO4B 3FDSC 1W60A 1VYMA 1VYJA 4CS5A 2NTIA 5H0TA 3GGRB 3LX2A 3HSLX 1UL1A 5DAIA 3K4XA 2HIIC 5JNED 3G65C 5HACA 3A1JC 2IX2C 2IZOC 2ZVLA 3I2MX 5B7OA 1B77A 3P83A 3P87A 2AVTA 4L60A 2HIKA 1GE8A 3GGRC 2ZVKA 5A6DA 2HIIA 5E0UA 4YHRA 2NTIB 4TR6A 1T6LA 3TBLA 3F1WA 5CFKA 3AIXA 3V62B 3LX1A 3GPMA 3AIXB 3AIZC 4L6PA 3U61F 4ZTDA 1B8HA 2ZVMA 1YYPA 2NTIC 2OD8A 3G65A 2HIKB 2IJXA 3V60B 3A1JA 2ZVVA 2IX2A 1PLQA 3WGWA 1RXMA 2ZVWA 3FDSD 2HIIB 1AXCA 1ISQA 5IWDA 1PLRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VKX A;  2IX2 B;  1RXZ A;  3GGR A;  3IFV A;  4RJF A;  3GPN A;  5IXA A;  1SXJ F;  1IZ4 A;  4HK1 A;  1DML A;  1U7B A;  2AWA A;  3A2F B;  3HI8 A;  5DA7 A;  5E0V A;  2HIK C;  2Z0L A;  3U60 F;  1RWZ A;  5E0T A;  3P91 A;  1CZD A;  5AUJ A;  1UD9 A;  1U76 A;  5IY4 A;  1IZ5 A;  2IO4 A;  3G65 B;  3AIZ A;  3A1J B;  4D2G A;  3U5Z F;  2IZO B;  3V61 B;  2IO4 B;  3FDS C;  1W60 A;  1VYM A;  1VYJ A;  4CS5 A;  2NTI A;  5H0T A;  3GGR B;  3LX2 A;  3HSL X;  1UL1 A;  5DAI A;  3K4X A;  2HII C;  5JNE D;  3G65 C;  5HAC A;  3A1J C;  2IX2 C;  2IZO C;  2ZVL A;  3I2M X;  5B7O A;  1B77 A;  3P83 A;  3P87 A;  2AVT A;  4L60 A;  2HIK A;  1GE8 A;  3GGR C;  2ZVK A;  5A6D A;  2HII A;  5E0U A;  4YHR A;  2NTI B;  4TR6 A;  1T6L A;  3TBL A;  3F1W A;  5CFK A;  3AIX A;  3V62 B;  3LX1 A;  3GPM A;  3AIX B;  3AIZ C;  4L6P A;  3U61 F;  4ZTD A;  1B8H A;  2ZVM A;  1YYP A;  2NTI C;  2OD8 A;  3G65 A;  2HIK B;  2IJX A;  3V60 B;  3A1J A;  2ZVV A;  2IX2 A;  1PLQ A;  3WGW A;  1RXM A;  2ZVW A;  3FDS D;  2HII B;  1AXC A;  1ISQ A;  5IWD A;  1PLR A; 
#chains in the Genus database with same CATH topology
 3VKX A;  2IX2 B;  1RXZ A;  3GGR A;  3IFV A;  4RJF A;  3GPN A;  5IXA A;  1SXJ F;  1IZ4 A;  4HK1 A;  1DML A;  1U7B A;  2AWA A;  3A2F B;  3HI8 A;  5DA7 A;  5E0V A;  2HIK C;  2Z0L A;  3U60 F;  1RWZ A;  5E0T A;  3P91 A;  1CZD A;  5AUJ A;  1UD9 A;  1U76 A;  5IY4 A;  1IZ5 A;  2IO4 A;  3G65 B;  3AIZ A;  3A1J B;  4D2G A;  3U5Z F;  2IZO B;  3V61 B;  2IO4 B;  3FDS C;  1W60 A;  1VYM A;  1VYJ A;  4CS5 A;  2NTI A;  5H0T A;  3GGR B;  3LX2 A;  3HSL X;  1UL1 A;  5DAI A;  3K4X A;  2HII C;  5JNE D;  3G65 C;  5HAC A;  3A1J C;  2IX2 C;  2IZO C;  2ZVL A;  3I2M X;  5B7O A;  1B77 A;  3P83 A;  3P87 A;  2AVT A;  4L60 A;  2HIK A;  1GE8 A;  3GGR C;  2ZVK A;  5A6D A;  2HII A;  5E0U A;  4YHR A;  2NTI B;  4TR6 A;  1T6L A;  3TBL A;  3F1W A;  5CFK A;  3AIX A;  3V62 B;  3LX1 A;  3GPM A;  3AIX B;  3AIZ C;  4L6P A;  3U61 F;  4ZTD A;  1B8H A;  2ZVM A;  1YYP A;  2NTI C;  2OD8 A;  3G65 A;  2HIK B;  2IJX A;  3V60 B;  3A1J A;  2ZVV A;  2IX2 A;  1PLQ A;  3WGW A;  1RXM A;  2ZVW A;  3FDS D;  2HII B;  1AXC A;  1ISQ A;  5IWD A;  1PLR A; 
#chains in the Genus database with same CATH homology
 3VKX A;  2IX2 B;  1RXZ A;  3GGR A;  3IFV A;  4RJF A;  3GPN A;  5IXA A;  1SXJ F;  1IZ4 A;  4HK1 A;  1DML A;  1U7B A;  2AWA A;  3A2F B;  3HI8 A;  5DA7 A;  5E0V A;  2HIK C;  2Z0L A;  3U60 F;  1RWZ A;  5E0T A;  3P91 A;  1CZD A;  5AUJ A;  1UD9 A;  1U76 A;  5IY4 A;  1IZ5 A;  2IO4 A;  3G65 B;  3AIZ A;  3A1J B;  4D2G A;  3U5Z F;  2IZO B;  3V61 B;  2IO4 B;  3FDS C;  1W60 A;  1VYM A;  1VYJ A;  4CS5 A;  2NTI A;  5H0T A;  3GGR B;  3LX2 A;  3HSL X;  1UL1 A;  5DAI A;  3K4X A;  2HII C;  5JNE D;  3G65 C;  5HAC A;  3A1J C;  2IX2 C;  2IZO C;  2ZVL A;  3I2M X;  5B7O A;  1B77 A;  3P83 A;  3P87 A;  2AVT A;  4L60 A;  2HIK A;  1GE8 A;  3GGR C;  2ZVK A;  5A6D A;  2HII A;  5E0U A;  4YHR A;  2NTI B;  4TR6 A;  1T6L A;  3TBL A;  3F1W A;  5CFK A;  3AIX A;  3V62 B;  3LX1 A;  3GPM A;  3AIX B;  3AIZ C;  4L6P A;  3U61 F;  4ZTD A;  1B8H A;  2ZVM A;  1YYP A;  2NTI C;  2OD8 A;  3G65 A;  2HIK B;  2IJX A;  3V60 B;  3A1J A;  2ZVV A;  2IX2 A;  1PLQ A;  3WGW A;  1RXM A;  2ZVW A;  3FDS D;  2HII B;  1AXC A;  1ISQ A;  5IWD A;  1PLR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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