2NTI | Genus

Total Genus 61

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	61
sequence length	244
structure length	244
Chain Sequence	MKVVYDDVRVLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYDVNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNREFNVRNLEVSEQEIPEINLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGESEVEVEFSKDTGGLQDLEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFFNMEGGGKVTYLLAPKV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 244 atoms

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244 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. pubmed doi rcsb
molecule keywords	DNA polymerase sliding clamp B
molecule tags	Dna binding protein
source organism	Sulfolobus solfataricus
total genus	61
structure length	244
sequence length	244
chains with identical sequence	F, I
ec nomenclature
pdb deposition date	2006-11-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00705	PCNA_N	Proliferating cell nuclear antigen, N-terminal domain
C	PF02747	PCNA_C	Proliferating cell nuclear antigen, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	2ntiC00

1YYPA 3F1WA 2NTIB 2IO4A 3K4XA 5E0TA 5B7OA 2ZVLA 5H0TA 1VYMA 3U5ZF 3U60F 1U7BA 1UD9A 1W60A 3G65C 5AUJA 5E0VA 5CFKA 1UL1A 3P87A 2IZOC 3FDSD 1RWZA 5DA7A 4ZTDA 1B8HA 2HIKC 3A1JB 1VYJA 3LX1A 3VKXA 5JNED 2OD8A 4L6PA 5E0UA 1RXMA 3IFVA 4D2GA 1DMLA 1PLRA 1IZ4A 5IY4A 1T6LA 2HIKA 3FDSC 2HIIB 2ZVKA 5A6DA 3GGRB 2AWAA 2NTIC 4L60A 3AIXA 2IX2B 3A1JA 3G65B 4YHRA 2IJXA 2IO4B 3P83A 2Z0LA 2ZVMA 3A2FB 2ZVVA 1U76A 2NTIA 3A1JC 1RXZA 3V61B 2AVTA 4RJFA 2ZVWA 4HK1A 3V62B 1IZ5A 3I2MX 3GPNA 3GPMA 4TR6A 5IWDA 1PLQA 3U61F 3AIZA 5HACA 5DAIA 2HIIC 3WGWA 1GE8A 3LX2A 3GGRC 2IZOB 5IXAA 3TBLA 4CS5A 1ISQA 2HIKB 2IX2C 1AXCA 3AIZC 3HI8A 1B77A 1CZDA 2HIIA 1SXJF 3AIXB 3GGRA 3P91A 2IX2A 3V60B 3G65A 3HSLX
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1YYP A;  3F1W A;  2NTI B;  2IO4 A;  3K4X A;  5E0T A;  5B7O A;  2ZVL A;  5H0T A;  1VYM A;  3U5Z F;  3U60 F;  1U7B A;  1UD9 A;  1W60 A;  3G65 C;  5AUJ A;  5E0V A;  5CFK A;  1UL1 A;  3P87 A;  2IZO C;  3FDS D;  1RWZ A;  5DA7 A;  4ZTD A;  1B8H A;  2HIK C;  3A1J B;  1VYJ A;  3LX1 A;  3VKX A;  5JNE D;  2OD8 A;  4L6P A;  5E0U A;  1RXM A;  3IFV A;  4D2G A;  1DML A;  1PLR A;  1IZ4 A;  5IY4 A;  1T6L A;  2HIK A;  3FDS C;  2HII B;  2ZVK A;  5A6D A;  3GGR B;  2AWA A;  2NTI C;  4L60 A;  3AIX A;  2IX2 B;  3A1J A;  3G65 B;  4YHR A;  2IJX A;  2IO4 B;  3P83 A;  2Z0L A;  2ZVM A;  3A2F B;  2ZVV A;  1U76 A;  2NTI A;  3A1J C;  1RXZ A;  3V61 B;  2AVT A;  4RJF A;  2ZVW A;  4HK1 A;  3V62 B;  1IZ5 A;  3I2M X;  3GPN A;  3GPM A;  4TR6 A;  5IWD A;  1PLQ A;  3U61 F;  3AIZ A;  5HAC A;  5DAI A;  2HII C;  3WGW A;  1GE8 A;  3LX2 A;  3GGR C;  2IZO B;  5IXA A;  3TBL A;  4CS5 A;  1ISQ A;  2HIK B;  2IX2 C;  1AXC A;  3AIZ C;  3HI8 A;  1B77 A;  1CZD A;  2HII A;  1SXJ F;  3AIX B;  3GGR A;  3P91 A;  2IX2 A;  3V60 B;  3G65 A;  3HSL X; 
#chains in the Genus database with same CATH topology
 1YYP A;  3F1W A;  2NTI B;  2IO4 A;  3K4X A;  5E0T A;  5B7O A;  2ZVL A;  5H0T A;  1VYM A;  3U5Z F;  3U60 F;  1U7B A;  1UD9 A;  1W60 A;  3G65 C;  5AUJ A;  5E0V A;  5CFK A;  1UL1 A;  3P87 A;  2IZO C;  3FDS D;  1RWZ A;  5DA7 A;  4ZTD A;  1B8H A;  2HIK C;  3A1J B;  1VYJ A;  3LX1 A;  3VKX A;  5JNE D;  2OD8 A;  4L6P A;  5E0U A;  1RXM A;  3IFV A;  4D2G A;  1DML A;  1PLR A;  1IZ4 A;  5IY4 A;  1T6L A;  2HIK A;  3FDS C;  2HII B;  2ZVK A;  5A6D A;  3GGR B;  2AWA A;  2NTI C;  4L60 A;  3AIX A;  2IX2 B;  3A1J A;  3G65 B;  4YHR A;  2IJX A;  2IO4 B;  3P83 A;  2Z0L A;  2ZVM A;  3A2F B;  2ZVV A;  1U76 A;  2NTI A;  3A1J C;  1RXZ A;  3V61 B;  2AVT A;  4RJF A;  2ZVW A;  4HK1 A;  3V62 B;  1IZ5 A;  3I2M X;  3GPN A;  3GPM A;  4TR6 A;  5IWD A;  1PLQ A;  3U61 F;  3AIZ A;  5HAC A;  5DAI A;  2HII C;  3WGW A;  1GE8 A;  3LX2 A;  3GGR C;  2IZO B;  5IXA A;  3TBL A;  4CS5 A;  1ISQ A;  2HIK B;  2IX2 C;  1AXC A;  3AIZ C;  3HI8 A;  1B77 A;  1CZD A;  2HII A;  1SXJ F;  3AIX B;  3GGR A;  3P91 A;  2IX2 A;  3V60 B;  3G65 A;  3HSL X; 
#chains in the Genus database with same CATH homology
 1YYP A;  3F1W A;  2NTI B;  2IO4 A;  3K4X A;  5E0T A;  5B7O A;  2ZVL A;  5H0T A;  1VYM A;  3U5Z F;  3U60 F;  1U7B A;  1UD9 A;  1W60 A;  3G65 C;  5AUJ A;  5E0V A;  5CFK A;  1UL1 A;  3P87 A;  2IZO C;  3FDS D;  1RWZ A;  5DA7 A;  4ZTD A;  1B8H A;  2HIK C;  3A1J B;  1VYJ A;  3LX1 A;  3VKX A;  5JNE D;  2OD8 A;  4L6P A;  5E0U A;  1RXM A;  3IFV A;  4D2G A;  1DML A;  1PLR A;  1IZ4 A;  5IY4 A;  1T6L A;  2HIK A;  3FDS C;  2HII B;  2ZVK A;  5A6D A;  3GGR B;  2AWA A;  2NTI C;  4L60 A;  3AIX A;  2IX2 B;  3A1J A;  3G65 B;  4YHR A;  2IJX A;  2IO4 B;  3P83 A;  2Z0L A;  2ZVM A;  3A2F B;  2ZVV A;  1U76 A;  2NTI A;  3A1J C;  1RXZ A;  3V61 B;  2AVT A;  4RJF A;  2ZVW A;  4HK1 A;  3V62 B;  1IZ5 A;  3I2M X;  3GPN A;  3GPM A;  4TR6 A;  5IWD A;  1PLQ A;  3U61 F;  3AIZ A;  5HAC A;  5DAI A;  2HII C;  3WGW A;  1GE8 A;  3LX2 A;  3GGR C;  2IZO B;  5IXA A;  3TBL A;  4CS5 A;  1ISQ A;  2HIK B;  2IX2 C;  1AXC A;  3AIZ C;  3HI8 A;  1B77 A;  1CZD A;  2HII A;  1SXJ F;  3AIX B;  3GGR A;  3P91 A;  2IX2 A;  3V60 B;  3G65 A;  3HSL X;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2NTIC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations