2ZVKA

Crystal structure of pcna in complex with dna polymerase eta fragment
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
255
structure length
246
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 53
structure length 246
sequence length 255
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2008-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2zvkA00
3VKXA 1PLRA 2HIKA 3V62B 1B77A 2HIIB 2IX2A 3WGWA 5IWDA 2ZVVA 3P83A 5DA7A 3LX2A 3GGRA 5H0TA 3HSLX 3P87A 2NTIC 2HIIC 3U61F 3AIZA 2ZVLA 1U7BA 1YYPA 3U5ZF 5A6DA 5IY4A 2NTIB 3K4XA 1IZ5A 3A1JC 4ZTDA 3AIXA 1UD9A 5IXAA 3V60B 1ISQA 1RXZA 2AVTA 1VYMA 3V61B 4CS5A 1GE8A 2HIKB 5E0TA 3P91A 3A1JB 5B7OA 5DAIA 1U76A 3A2FB 3G65C 1B8HA 2ZVMA 2HIKC 2IZOC 5E0UA 1VYJA 1SXJF 2IO4A 5AUJA 3TBLA 3LX1A 3G65B 3HI8A 2IX2C 2OD8A 2IZOB 2HIIA 3GGRC 1RXMA 3FDSC 3F1WA 3AIXB 2ZVKA 2IX2B 3AIZC 4HK1A 2IJXA 3GPMA 2AWAA 3FDSD 1CZDA 4RJFA 5CFKA 3A1JA 2ZVWA 3GGRB 4YHRA 5JNED 4L60A 3U60F 4D2GA 1T6LA 4L6PA 3GPNA 5E0VA 1PLQA 4TR6A 3IFVA 5HACA 1AXCA 2NTIA 1W60A 3I2MX 1DMLA 1UL1A 2Z0LA 2IO4B 1IZ4A 3G65A 1RWZA
chains in the Genus database with same CATH superfamily
3VKXA 1PLRA 2HIKA 3V62B 1B77A 2HIIB 2IX2A 3WGWA 5IWDA 2ZVVA 3P83A 5DA7A 3LX2A 3GGRA 5H0TA 3HSLX 3P87A 2NTIC 2HIIC 3U61F 3AIZA 2ZVLA 1U7BA 1YYPA 3U5ZF 5A6DA 5IY4A 2NTIB 3K4XA 1IZ5A 3A1JC 4ZTDA 3AIXA 1UD9A 5IXAA 3V60B 1ISQA 1RXZA 2AVTA 1VYMA 3V61B 4CS5A 1GE8A 2HIKB 5E0TA 3P91A 3A1JB 5B7OA 5DAIA 1U76A 3A2FB 3G65C 1B8HA 2ZVMA 2HIKC 2IZOC 5E0UA 1VYJA 1SXJF 2IO4A 5AUJA 3TBLA 3LX1A 3G65B 3HI8A 2IX2C 2OD8A 2IZOB 2HIIA 3GGRC 1RXMA 3FDSC 3F1WA 3AIXB 2ZVKA 2IX2B 3AIZC 4HK1A 2IJXA 3GPMA 2AWAA 3FDSD 1CZDA 4RJFA 5CFKA 3A1JA 2ZVWA 3GGRB 4YHRA 5JNED 4L60A 3U60F 4D2GA 1T6LA 4L6PA 3GPNA 5E0VA 1PLQA 4TR6A 3IFVA 5HACA 1AXCA 2NTIA 1W60A 3I2MX 1DMLA 1UL1A 2Z0LA 2IO4B 1IZ4A 3G65A 1RWZA
chains in the Genus database with same CATH topology
3VKXA 1PLRA 2HIKA 3V62B 1B77A 2HIIB 2IX2A 3WGWA 5IWDA 2ZVVA 3P83A 5DA7A 3LX2A 3GGRA 5H0TA 3HSLX 3P87A 2NTIC 2HIIC 3U61F 3AIZA 2ZVLA 1U7BA 1YYPA 3U5ZF 5A6DA 5IY4A 2NTIB 3K4XA 1IZ5A 3A1JC 4ZTDA 3AIXA 1UD9A 5IXAA 3V60B 1ISQA 1RXZA 2AVTA 1VYMA 3V61B 4CS5A 1GE8A 2HIKB 5E0TA 3P91A 3A1JB 5B7OA 5DAIA 1U76A 3A2FB 3G65C 1B8HA 2ZVMA 2HIKC 2IZOC 5E0UA 1VYJA 1SXJF 2IO4A 5AUJA 3TBLA 3LX1A 3G65B 3HI8A 2IX2C 2OD8A 2IZOB 2HIIA 3GGRC 1RXMA 3FDSC 3F1WA 3AIXB 2ZVKA 2IX2B 3AIZC 4HK1A 2IJXA 3GPMA 2AWAA 3FDSD 1CZDA 4RJFA 5CFKA 3A1JA 2ZVWA 3GGRB 4YHRA 5JNED 4L60A 3U60F 4D2GA 1T6LA 4L6PA 3GPNA 5E0VA 1PLQA 4TR6A 3IFVA 5HACA 1AXCA 2NTIA 1W60A 3I2MX 1DMLA 1UL1A 2Z0LA 2IO4B 1IZ4A 3G65A 1RWZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VKX A;  1PLR A;  2HIK A;  3V62 B;  1B77 A;  2HII B;  2IX2 A;  3WGW A;  5IWD A;  2ZVV A;  3P83 A;  5DA7 A;  3LX2 A;  3GGR A;  5H0T A;  3HSL X;  3P87 A;  2NTI C;  2HII C;  3U61 F;  3AIZ A;  2ZVL A;  1U7B A;  1YYP A;  3U5Z F;  5A6D A;  5IY4 A;  2NTI B;  3K4X A;  1IZ5 A;  3A1J C;  4ZTD A;  3AIX A;  1UD9 A;  5IXA A;  3V60 B;  1ISQ A;  1RXZ A;  2AVT A;  1VYM A;  3V61 B;  4CS5 A;  1GE8 A;  2HIK B;  5E0T A;  3P91 A;  3A1J B;  5B7O A;  5DAI A;  1U76 A;  3A2F B;  3G65 C;  1B8H A;  2ZVM A;  2HIK C;  2IZO C;  5E0U A;  1VYJ A;  1SXJ F;  2IO4 A;  5AUJ A;  3TBL A;  3LX1 A;  3G65 B;  3HI8 A;  2IX2 C;  2OD8 A;  2IZO B;  2HII A;  3GGR C;  1RXM A;  3FDS C;  3F1W A;  3AIX B;  2ZVK A;  2IX2 B;  3AIZ C;  4HK1 A;  2IJX A;  3GPM A;  2AWA A;  3FDS D;  1CZD A;  4RJF A;  5CFK A;  3A1J A;  2ZVW A;  3GGR B;  4YHR A;  5JNE D;  4L60 A;  3U60 F;  4D2G A;  1T6L A;  4L6P A;  3GPN A;  5E0V A;  1PLQ A;  4TR6 A;  3IFV A;  5HAC A;  1AXC A;  2NTI A;  1W60 A;  3I2M X;  1DML A;  1UL1 A;  2Z0L A;  2IO4 B;  1IZ4 A;  3G65 A;  1RWZ A; 
#chains in the Genus database with same CATH topology
 3VKX A;  1PLR A;  2HIK A;  3V62 B;  1B77 A;  2HII B;  2IX2 A;  3WGW A;  5IWD A;  2ZVV A;  3P83 A;  5DA7 A;  3LX2 A;  3GGR A;  5H0T A;  3HSL X;  3P87 A;  2NTI C;  2HII C;  3U61 F;  3AIZ A;  2ZVL A;  1U7B A;  1YYP A;  3U5Z F;  5A6D A;  5IY4 A;  2NTI B;  3K4X A;  1IZ5 A;  3A1J C;  4ZTD A;  3AIX A;  1UD9 A;  5IXA A;  3V60 B;  1ISQ A;  1RXZ A;  2AVT A;  1VYM A;  3V61 B;  4CS5 A;  1GE8 A;  2HIK B;  5E0T A;  3P91 A;  3A1J B;  5B7O A;  5DAI A;  1U76 A;  3A2F B;  3G65 C;  1B8H A;  2ZVM A;  2HIK C;  2IZO C;  5E0U A;  1VYJ A;  1SXJ F;  2IO4 A;  5AUJ A;  3TBL A;  3LX1 A;  3G65 B;  3HI8 A;  2IX2 C;  2OD8 A;  2IZO B;  2HII A;  3GGR C;  1RXM A;  3FDS C;  3F1W A;  3AIX B;  2ZVK A;  2IX2 B;  3AIZ C;  4HK1 A;  2IJX A;  3GPM A;  2AWA A;  3FDS D;  1CZD A;  4RJF A;  5CFK A;  3A1J A;  2ZVW A;  3GGR B;  4YHR A;  5JNE D;  4L60 A;  3U60 F;  4D2G A;  1T6L A;  4L6P A;  3GPN A;  5E0V A;  1PLQ A;  4TR6 A;  3IFV A;  5HAC A;  1AXC A;  2NTI A;  1W60 A;  3I2M X;  1DML A;  1UL1 A;  2Z0L A;  2IO4 B;  1IZ4 A;  3G65 A;  1RWZ A; 
#chains in the Genus database with same CATH homology
 3VKX A;  1PLR A;  2HIK A;  3V62 B;  1B77 A;  2HII B;  2IX2 A;  3WGW A;  5IWD A;  2ZVV A;  3P83 A;  5DA7 A;  3LX2 A;  3GGR A;  5H0T A;  3HSL X;  3P87 A;  2NTI C;  2HII C;  3U61 F;  3AIZ A;  2ZVL A;  1U7B A;  1YYP A;  3U5Z F;  5A6D A;  5IY4 A;  2NTI B;  3K4X A;  1IZ5 A;  3A1J C;  4ZTD A;  3AIX A;  1UD9 A;  5IXA A;  3V60 B;  1ISQ A;  1RXZ A;  2AVT A;  1VYM A;  3V61 B;  4CS5 A;  1GE8 A;  2HIK B;  5E0T A;  3P91 A;  3A1J B;  5B7O A;  5DAI A;  1U76 A;  3A2F B;  3G65 C;  1B8H A;  2ZVM A;  2HIK C;  2IZO C;  5E0U A;  1VYJ A;  1SXJ F;  2IO4 A;  5AUJ A;  3TBL A;  3LX1 A;  3G65 B;  3HI8 A;  2IX2 C;  2OD8 A;  2IZO B;  2HII A;  3GGR C;  1RXM A;  3FDS C;  3F1W A;  3AIX B;  2ZVK A;  2IX2 B;  3AIZ C;  4HK1 A;  2IJX A;  3GPM A;  2AWA A;  3FDS D;  1CZD A;  4RJF A;  5CFK A;  3A1J A;  2ZVW A;  3GGR B;  4YHR A;  5JNE D;  4L60 A;  3U60 F;  4D2G A;  1T6L A;  4L6P A;  3GPN A;  5E0V A;  1PLQ A;  4TR6 A;  3IFV A;  5HAC A;  1AXC A;  2NTI A;  1W60 A;  3I2M X;  1DML A;  1UL1 A;  2Z0L A;  2IO4 B;  1IZ4 A;  3G65 A;  1RWZ A; 
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similar chains in the Genus database (?% sequence similarity)
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