2ZVKA

Crystal structure of pcna in complex with dna polymerase eta fragment
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
255
structure length
246
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 53
structure length 246
sequence length 255
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2008-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2zvkA00
2ZVVA 2NTIB 3LX2A 2IX2B 1RXMA 2ZVMA 2AVTA 5E0VA 2IZOB 3G65B 3GGRB 5AUJA 5CFKA 3AIZC 2HIKA 3P87A 3V61B 1VYJA 3AIZA 5DA7A 1IZ5A 1AXCA 4TR6A 3AIXA 2ZVWA 1B77A 2HIKB 5IY4A 1CZDA 1PLRA 5IXAA 4RJFA 1B8HA 2HIIB 3GPNA 5E0TA 1RXZA 2AWAA 1T6LA 3A1JC 5DAIA 3FDSC 3A1JA 5E0UA 5A6DA 2OD8A 3HI8A 1YYPA 2ZVLA 1DMLA 1U76A 2ZVKA 3V62B 3P83A 1SXJF 1RWZA 2IO4A 3P91A 3LX1A 3AIXB 4L6PA 1PLQA 3A2FB 1ISQA 1UD9A 2NTIC 3FDSD 2IX2C 2NTIA 3U5ZF 3V60B 4YHRA 4HK1A 3F1WA 3G65C 3GGRC 1W60A 3GGRA 3G65A 2Z0LA 3U61F 5JNED 5H0TA 4CS5A 3A1JB 3I2MX 3U60F 4ZTDA 3HSLX 5HACA 2HIKC 1IZ4A 3IFVA 3TBLA 1GE8A 3VKXA 1UL1A 5B7OA 3WGWA 2IO4B 3K4XA 1U7BA 2HIIC 2IX2A 4L60A 4D2GA 2IZOC 2HIIA 1VYMA 2IJXA 3GPMA 5IWDA
chains in the Genus database with same CATH superfamily
2ZVVA 2NTIB 3LX2A 2IX2B 1RXMA 2ZVMA 2AVTA 5E0VA 2IZOB 3G65B 3GGRB 5AUJA 5CFKA 3AIZC 2HIKA 3P87A 3V61B 1VYJA 3AIZA 5DA7A 1IZ5A 1AXCA 4TR6A 3AIXA 2ZVWA 1B77A 2HIKB 5IY4A 1CZDA 1PLRA 5IXAA 4RJFA 1B8HA 2HIIB 3GPNA 5E0TA 1RXZA 2AWAA 1T6LA 3A1JC 5DAIA 3FDSC 3A1JA 5E0UA 5A6DA 2OD8A 3HI8A 1YYPA 2ZVLA 1DMLA 1U76A 2ZVKA 3V62B 3P83A 1SXJF 1RWZA 2IO4A 3P91A 3LX1A 3AIXB 4L6PA 1PLQA 3A2FB 1ISQA 1UD9A 2NTIC 3FDSD 2IX2C 2NTIA 3U5ZF 3V60B 4YHRA 4HK1A 3F1WA 3G65C 3GGRC 1W60A 3GGRA 3G65A 2Z0LA 3U61F 5JNED 5H0TA 4CS5A 3A1JB 3I2MX 3U60F 4ZTDA 3HSLX 5HACA 2HIKC 1IZ4A 3IFVA 3TBLA 1GE8A 3VKXA 1UL1A 5B7OA 3WGWA 2IO4B 3K4XA 1U7BA 2HIIC 2IX2A 4L60A 4D2GA 2IZOC 2HIIA 1VYMA 2IJXA 3GPMA 5IWDA
chains in the Genus database with same CATH topology
2ZVVA 2NTIB 3LX2A 2IX2B 1RXMA 2ZVMA 2AVTA 5E0VA 2IZOB 3G65B 3GGRB 5AUJA 5CFKA 3AIZC 2HIKA 3P87A 3V61B 1VYJA 3AIZA 5DA7A 1IZ5A 1AXCA 4TR6A 3AIXA 2ZVWA 1B77A 2HIKB 5IY4A 1CZDA 1PLRA 5IXAA 4RJFA 1B8HA 2HIIB 3GPNA 5E0TA 1RXZA 2AWAA 1T6LA 3A1JC 5DAIA 3FDSC 3A1JA 5E0UA 5A6DA 2OD8A 3HI8A 1YYPA 2ZVLA 1DMLA 1U76A 2ZVKA 3V62B 3P83A 1SXJF 1RWZA 2IO4A 3P91A 3LX1A 3AIXB 4L6PA 1PLQA 3A2FB 1ISQA 1UD9A 2NTIC 3FDSD 2IX2C 2NTIA 3U5ZF 3V60B 4YHRA 4HK1A 3F1WA 3G65C 3GGRC 1W60A 3GGRA 3G65A 2Z0LA 3U61F 5JNED 5H0TA 4CS5A 3A1JB 3I2MX 3U60F 4ZTDA 3HSLX 5HACA 2HIKC 1IZ4A 3IFVA 3TBLA 1GE8A 3VKXA 1UL1A 5B7OA 3WGWA 2IO4B 3K4XA 1U7BA 2HIIC 2IX2A 4L60A 4D2GA 2IZOC 2HIIA 1VYMA 2IJXA 3GPMA 5IWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVV A;  2NTI B;  3LX2 A;  2IX2 B;  1RXM A;  2ZVM A;  2AVT A;  5E0V A;  2IZO B;  3G65 B;  3GGR B;  5AUJ A;  5CFK A;  3AIZ C;  2HIK A;  3P87 A;  3V61 B;  1VYJ A;  3AIZ A;  5DA7 A;  1IZ5 A;  1AXC A;  4TR6 A;  3AIX A;  2ZVW A;  1B77 A;  2HIK B;  5IY4 A;  1CZD A;  1PLR A;  5IXA A;  4RJF A;  1B8H A;  2HII B;  3GPN A;  5E0T A;  1RXZ A;  2AWA A;  1T6L A;  3A1J C;  5DAI A;  3FDS C;  3A1J A;  5E0U A;  5A6D A;  2OD8 A;  3HI8 A;  1YYP A;  2ZVL A;  1DML A;  1U76 A;  2ZVK A;  3V62 B;  3P83 A;  1SXJ F;  1RWZ A;  2IO4 A;  3P91 A;  3LX1 A;  3AIX B;  4L6P A;  1PLQ A;  3A2F B;  1ISQ A;  1UD9 A;  2NTI C;  3FDS D;  2IX2 C;  2NTI A;  3U5Z F;  3V60 B;  4YHR A;  4HK1 A;  3F1W A;  3G65 C;  3GGR C;  1W60 A;  3GGR A;  3G65 A;  2Z0L A;  3U61 F;  5JNE D;  5H0T A;  4CS5 A;  3A1J B;  3I2M X;  3U60 F;  4ZTD A;  3HSL X;  5HAC A;  2HIK C;  1IZ4 A;  3IFV A;  3TBL A;  1GE8 A;  3VKX A;  1UL1 A;  5B7O A;  3WGW A;  2IO4 B;  3K4X A;  1U7B A;  2HII C;  2IX2 A;  4L60 A;  4D2G A;  2IZO C;  2HII A;  1VYM A;  2IJX A;  3GPM A;  5IWD A; 
#chains in the Genus database with same CATH topology
 2ZVV A;  2NTI B;  3LX2 A;  2IX2 B;  1RXM A;  2ZVM A;  2AVT A;  5E0V A;  2IZO B;  3G65 B;  3GGR B;  5AUJ A;  5CFK A;  3AIZ C;  2HIK A;  3P87 A;  3V61 B;  1VYJ A;  3AIZ A;  5DA7 A;  1IZ5 A;  1AXC A;  4TR6 A;  3AIX A;  2ZVW A;  1B77 A;  2HIK B;  5IY4 A;  1CZD A;  1PLR A;  5IXA A;  4RJF A;  1B8H A;  2HII B;  3GPN A;  5E0T A;  1RXZ A;  2AWA A;  1T6L A;  3A1J C;  5DAI A;  3FDS C;  3A1J A;  5E0U A;  5A6D A;  2OD8 A;  3HI8 A;  1YYP A;  2ZVL A;  1DML A;  1U76 A;  2ZVK A;  3V62 B;  3P83 A;  1SXJ F;  1RWZ A;  2IO4 A;  3P91 A;  3LX1 A;  3AIX B;  4L6P A;  1PLQ A;  3A2F B;  1ISQ A;  1UD9 A;  2NTI C;  3FDS D;  2IX2 C;  2NTI A;  3U5Z F;  3V60 B;  4YHR A;  4HK1 A;  3F1W A;  3G65 C;  3GGR C;  1W60 A;  3GGR A;  3G65 A;  2Z0L A;  3U61 F;  5JNE D;  5H0T A;  4CS5 A;  3A1J B;  3I2M X;  3U60 F;  4ZTD A;  3HSL X;  5HAC A;  2HIK C;  1IZ4 A;  3IFV A;  3TBL A;  1GE8 A;  3VKX A;  1UL1 A;  5B7O A;  3WGW A;  2IO4 B;  3K4X A;  1U7B A;  2HII C;  2IX2 A;  4L60 A;  4D2G A;  2IZO C;  2HII A;  1VYM A;  2IJX A;  3GPM A;  5IWD A; 
#chains in the Genus database with same CATH homology
 2ZVV A;  2NTI B;  3LX2 A;  2IX2 B;  1RXM A;  2ZVM A;  2AVT A;  5E0V A;  2IZO B;  3G65 B;  3GGR B;  5AUJ A;  5CFK A;  3AIZ C;  2HIK A;  3P87 A;  3V61 B;  1VYJ A;  3AIZ A;  5DA7 A;  1IZ5 A;  1AXC A;  4TR6 A;  3AIX A;  2ZVW A;  1B77 A;  2HIK B;  5IY4 A;  1CZD A;  1PLR A;  5IXA A;  4RJF A;  1B8H A;  2HII B;  3GPN A;  5E0T A;  1RXZ A;  2AWA A;  1T6L A;  3A1J C;  5DAI A;  3FDS C;  3A1J A;  5E0U A;  5A6D A;  2OD8 A;  3HI8 A;  1YYP A;  2ZVL A;  1DML A;  1U76 A;  2ZVK A;  3V62 B;  3P83 A;  1SXJ F;  1RWZ A;  2IO4 A;  3P91 A;  3LX1 A;  3AIX B;  4L6P A;  1PLQ A;  3A2F B;  1ISQ A;  1UD9 A;  2NTI C;  3FDS D;  2IX2 C;  2NTI A;  3U5Z F;  3V60 B;  4YHR A;  4HK1 A;  3F1W A;  3G65 C;  3GGR C;  1W60 A;  3GGR A;  3G65 A;  2Z0L A;  3U61 F;  5JNE D;  5H0T A;  4CS5 A;  3A1J B;  3I2M X;  3U60 F;  4ZTD A;  3HSL X;  5HAC A;  2HIK C;  1IZ4 A;  3IFV A;  3TBL A;  1GE8 A;  3VKX A;  1UL1 A;  5B7O A;  3WGW A;  2IO4 B;  3K4X A;  1U7B A;  2HII C;  2IX2 A;  4L60 A;  4D2G A;  2IZO C;  2HII A;  1VYM A;  2IJX A;  3GPM A;  5IWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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