2ZVMA

Crystal structure of pcna in complex with dna polymerase iota fragment
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
255
structure length
248
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 58
structure length 248
sequence length 255
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2008-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2zvmA00
3F1WA 4ZTDA 3GPMA 3GGRC 3HSLX 3LX1A 1SXJF 2IO4B 1DMLA 3P87A 3A1JB 1PLRA 3AIXA 3P83A 3K4XA 3FDSD 2HIKC 5E0TA 3TBLA 4D2GA 3GGRA 1PLQA 3GPNA 2IJXA 3AIZC 3VKXA 5AUJA 1ISQA 2HIKA 4L6PA 5CFKA 1YYPA 3AIZA 1UL1A 2HIIC 1AXCA 1RXMA 5HACA 5IY4A 2IZOB 3FDSC 2ZVKA 5A6DA 1U76A 2HIIA 2NTIB 1RWZA 2IX2B 1T6LA 1RXZA 3A1JC 2IZOC 1CZDA 3G65B 1B77A 1UD9A 5JNED 2ZVWA 3V62B 3V61B 5B7OA 1IZ4A 3P91A 2NTIC 2IO4A 2IX2C 3A1JA 5DA7A 4YHRA 4RJFA 3AIXB 3U60F 5H0TA 4TR6A 2NTIA 2IX2A 1VYMA 1U7BA 4L60A 3U5ZF 2AVTA 3I2MX 3IFVA 2HIKB 4CS5A 1GE8A 5E0VA 1VYJA 1IZ5A 5IWDA 3LX2A 2OD8A 3A2FB 2Z0LA 3HI8A 2ZVLA 3G65C 3U61F 1B8HA 5IXAA 3WGWA 5DAIA 5E0UA 2ZVMA 3GGRB 4HK1A 2HIIB 1W60A 2AWAA 3G65A 2ZVVA 3V60B
chains in the Genus database with same CATH superfamily
3F1WA 4ZTDA 3GPMA 3GGRC 3HSLX 3LX1A 1SXJF 2IO4B 1DMLA 3P87A 3A1JB 1PLRA 3AIXA 3P83A 3K4XA 3FDSD 2HIKC 5E0TA 3TBLA 4D2GA 3GGRA 1PLQA 3GPNA 2IJXA 3AIZC 3VKXA 5AUJA 1ISQA 2HIKA 4L6PA 5CFKA 1YYPA 3AIZA 1UL1A 2HIIC 1AXCA 1RXMA 5HACA 5IY4A 2IZOB 3FDSC 2ZVKA 5A6DA 1U76A 2HIIA 2NTIB 1RWZA 2IX2B 1T6LA 1RXZA 3A1JC 2IZOC 1CZDA 3G65B 1B77A 1UD9A 5JNED 2ZVWA 3V62B 3V61B 5B7OA 1IZ4A 3P91A 2NTIC 2IO4A 2IX2C 3A1JA 5DA7A 4YHRA 4RJFA 3AIXB 3U60F 5H0TA 4TR6A 2NTIA 2IX2A 1VYMA 1U7BA 4L60A 3U5ZF 2AVTA 3I2MX 3IFVA 2HIKB 4CS5A 1GE8A 5E0VA 1VYJA 1IZ5A 5IWDA 3LX2A 2OD8A 3A2FB 2Z0LA 3HI8A 2ZVLA 3G65C 3U61F 1B8HA 5IXAA 3WGWA 5DAIA 5E0UA 2ZVMA 3GGRB 4HK1A 2HIIB 1W60A 2AWAA 3G65A 2ZVVA 3V60B
chains in the Genus database with same CATH topology
3F1WA 4ZTDA 3GPMA 3GGRC 3HSLX 3LX1A 1SXJF 2IO4B 1DMLA 3P87A 3A1JB 1PLRA 3AIXA 3P83A 3K4XA 3FDSD 2HIKC 5E0TA 3TBLA 4D2GA 3GGRA 1PLQA 3GPNA 2IJXA 3AIZC 3VKXA 5AUJA 1ISQA 2HIKA 4L6PA 5CFKA 1YYPA 3AIZA 1UL1A 2HIIC 1AXCA 1RXMA 5HACA 5IY4A 2IZOB 3FDSC 2ZVKA 5A6DA 1U76A 2HIIA 2NTIB 1RWZA 2IX2B 1T6LA 1RXZA 3A1JC 2IZOC 1CZDA 3G65B 1B77A 1UD9A 5JNED 2ZVWA 3V62B 3V61B 5B7OA 1IZ4A 3P91A 2NTIC 2IO4A 2IX2C 3A1JA 5DA7A 4YHRA 4RJFA 3AIXB 3U60F 5H0TA 4TR6A 2NTIA 2IX2A 1VYMA 1U7BA 4L60A 3U5ZF 2AVTA 3I2MX 3IFVA 2HIKB 4CS5A 1GE8A 5E0VA 1VYJA 1IZ5A 5IWDA 3LX2A 2OD8A 3A2FB 2Z0LA 3HI8A 2ZVLA 3G65C 3U61F 1B8HA 5IXAA 3WGWA 5DAIA 5E0UA 2ZVMA 3GGRB 4HK1A 2HIIB 1W60A 2AWAA 3G65A 2ZVVA 3V60B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F1W A;  4ZTD A;  3GPM A;  3GGR C;  3HSL X;  3LX1 A;  1SXJ F;  2IO4 B;  1DML A;  3P87 A;  3A1J B;  1PLR A;  3AIX A;  3P83 A;  3K4X A;  3FDS D;  2HIK C;  5E0T A;  3TBL A;  4D2G A;  3GGR A;  1PLQ A;  3GPN A;  2IJX A;  3AIZ C;  3VKX A;  5AUJ A;  1ISQ A;  2HIK A;  4L6P A;  5CFK A;  1YYP A;  3AIZ A;  1UL1 A;  2HII C;  1AXC A;  1RXM A;  5HAC A;  5IY4 A;  2IZO B;  3FDS C;  2ZVK A;  5A6D A;  1U76 A;  2HII A;  2NTI B;  1RWZ A;  2IX2 B;  1T6L A;  1RXZ A;  3A1J C;  2IZO C;  1CZD A;  3G65 B;  1B77 A;  1UD9 A;  5JNE D;  2ZVW A;  3V62 B;  3V61 B;  5B7O A;  1IZ4 A;  3P91 A;  2NTI C;  2IO4 A;  2IX2 C;  3A1J A;  5DA7 A;  4YHR A;  4RJF A;  3AIX B;  3U60 F;  5H0T A;  4TR6 A;  2NTI A;  2IX2 A;  1VYM A;  1U7B A;  4L60 A;  3U5Z F;  2AVT A;  3I2M X;  3IFV A;  2HIK B;  4CS5 A;  1GE8 A;  5E0V A;  1VYJ A;  1IZ5 A;  5IWD A;  3LX2 A;  2OD8 A;  3A2F B;  2Z0L A;  3HI8 A;  2ZVL A;  3G65 C;  3U61 F;  1B8H A;  5IXA A;  3WGW A;  5DAI A;  5E0U A;  2ZVM A;  3GGR B;  4HK1 A;  2HII B;  1W60 A;  2AWA A;  3G65 A;  2ZVV A;  3V60 B; 
#chains in the Genus database with same CATH topology
 3F1W A;  4ZTD A;  3GPM A;  3GGR C;  3HSL X;  3LX1 A;  1SXJ F;  2IO4 B;  1DML A;  3P87 A;  3A1J B;  1PLR A;  3AIX A;  3P83 A;  3K4X A;  3FDS D;  2HIK C;  5E0T A;  3TBL A;  4D2G A;  3GGR A;  1PLQ A;  3GPN A;  2IJX A;  3AIZ C;  3VKX A;  5AUJ A;  1ISQ A;  2HIK A;  4L6P A;  5CFK A;  1YYP A;  3AIZ A;  1UL1 A;  2HII C;  1AXC A;  1RXM A;  5HAC A;  5IY4 A;  2IZO B;  3FDS C;  2ZVK A;  5A6D A;  1U76 A;  2HII A;  2NTI B;  1RWZ A;  2IX2 B;  1T6L A;  1RXZ A;  3A1J C;  2IZO C;  1CZD A;  3G65 B;  1B77 A;  1UD9 A;  5JNE D;  2ZVW A;  3V62 B;  3V61 B;  5B7O A;  1IZ4 A;  3P91 A;  2NTI C;  2IO4 A;  2IX2 C;  3A1J A;  5DA7 A;  4YHR A;  4RJF A;  3AIX B;  3U60 F;  5H0T A;  4TR6 A;  2NTI A;  2IX2 A;  1VYM A;  1U7B A;  4L60 A;  3U5Z F;  2AVT A;  3I2M X;  3IFV A;  2HIK B;  4CS5 A;  1GE8 A;  5E0V A;  1VYJ A;  1IZ5 A;  5IWD A;  3LX2 A;  2OD8 A;  3A2F B;  2Z0L A;  3HI8 A;  2ZVL A;  3G65 C;  3U61 F;  1B8H A;  5IXA A;  3WGW A;  5DAI A;  5E0U A;  2ZVM A;  3GGR B;  4HK1 A;  2HII B;  1W60 A;  2AWA A;  3G65 A;  2ZVV A;  3V60 B; 
#chains in the Genus database with same CATH homology
 3F1W A;  4ZTD A;  3GPM A;  3GGR C;  3HSL X;  3LX1 A;  1SXJ F;  2IO4 B;  1DML A;  3P87 A;  3A1J B;  1PLR A;  3AIX A;  3P83 A;  3K4X A;  3FDS D;  2HIK C;  5E0T A;  3TBL A;  4D2G A;  3GGR A;  1PLQ A;  3GPN A;  2IJX A;  3AIZ C;  3VKX A;  5AUJ A;  1ISQ A;  2HIK A;  4L6P A;  5CFK A;  1YYP A;  3AIZ A;  1UL1 A;  2HII C;  1AXC A;  1RXM A;  5HAC A;  5IY4 A;  2IZO B;  3FDS C;  2ZVK A;  5A6D A;  1U76 A;  2HII A;  2NTI B;  1RWZ A;  2IX2 B;  1T6L A;  1RXZ A;  3A1J C;  2IZO C;  1CZD A;  3G65 B;  1B77 A;  1UD9 A;  5JNE D;  2ZVW A;  3V62 B;  3V61 B;  5B7O A;  1IZ4 A;  3P91 A;  2NTI C;  2IO4 A;  2IX2 C;  3A1J A;  5DA7 A;  4YHR A;  4RJF A;  3AIX B;  3U60 F;  5H0T A;  4TR6 A;  2NTI A;  2IX2 A;  1VYM A;  1U7B A;  4L60 A;  3U5Z F;  2AVT A;  3I2M X;  3IFV A;  2HIK B;  4CS5 A;  1GE8 A;  5E0V A;  1VYJ A;  1IZ5 A;  5IWD A;  3LX2 A;  2OD8 A;  3A2F B;  2Z0L A;  3HI8 A;  2ZVL A;  3G65 C;  3U61 F;  1B8H A;  5IXA A;  3WGW A;  5DAI A;  5E0U A;  2ZVM A;  3GGR B;  4HK1 A;  2HII B;  1W60 A;  2AWA A;  3G65 A;  2ZVV A;  3V60 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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