2ZVMA

Crystal structure of pcna in complex with dna polymerase iota fragment
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
255
structure length
248
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
pubmed doi rcsb
molecule keywords Proliferating cell nuclear antigen
total genus 58
structure length 248
sequence length 255
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2008-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2zvmA00
2IJXA 1VYMA 4YHRA 1CZDA 2ZVKA 5E0UA 4D2GA 4CS5A 1GE8A 3U61F 4L60A 4TR6A 3VKXA 5B7OA 3A1JC 2IZOC 5JNED 2ZVMA 3I2MX 2HIKC 3AIZC 1YYPA 3GGRC 3V62B 5HACA 2HIIB 3HSLX 3WGWA 1IZ4A 2HIIA 1U7BA 4L6PA 5A6DA 1RXMA 2NTIC 1RXZA 5E0TA 5DAIA 1T6LA 2ZVWA 2IX2C 3P83A 2Z0LA 4ZTDA 3V60B 1B8HA 2IO4A 1RWZA 3K4XA 3HI8A 3G65C 3V61B 2AVTA 3U60F 3TBLA 1UL1A 3A2FB 3GPMA 3LX1A 1PLQA 3F1WA 3A1JA 5CFKA 1ISQA 2HIKA 3AIZA 3GGRA 2IO4B 5AUJA 1B77A 1SXJF 5E0VA 2ZVVA 4HK1A 2NTIB 5DA7A 2HIIC 5IY4A 1U76A 4RJFA 2NTIA 2AWAA 1UD9A 3IFVA 1AXCA 1IZ5A 3FDSD 3P87A 3U5ZF 2IX2B 2IZOB 3A1JB 3P91A 3FDSC 2IX2A 5IWDA 1W60A 2HIKB 2ZVLA 2OD8A 3AIXB 1PLRA 3GGRB 1VYJA 3AIXA 5H0TA 5IXAA 3GPNA 3G65B 3LX2A 3G65A 1DMLA
chains in the Genus database with same CATH superfamily
2IJXA 1VYMA 4YHRA 1CZDA 2ZVKA 5E0UA 4D2GA 4CS5A 1GE8A 3U61F 4L60A 4TR6A 3VKXA 5B7OA 3A1JC 2IZOC 5JNED 2ZVMA 3I2MX 2HIKC 3AIZC 1YYPA 3GGRC 3V62B 5HACA 2HIIB 3HSLX 3WGWA 1IZ4A 2HIIA 1U7BA 4L6PA 5A6DA 1RXMA 2NTIC 1RXZA 5E0TA 5DAIA 1T6LA 2ZVWA 2IX2C 3P83A 2Z0LA 4ZTDA 3V60B 1B8HA 2IO4A 1RWZA 3K4XA 3HI8A 3G65C 3V61B 2AVTA 3U60F 3TBLA 1UL1A 3A2FB 3GPMA 3LX1A 1PLQA 3F1WA 3A1JA 5CFKA 1ISQA 2HIKA 3AIZA 3GGRA 2IO4B 5AUJA 1B77A 1SXJF 5E0VA 2ZVVA 4HK1A 2NTIB 5DA7A 2HIIC 5IY4A 1U76A 4RJFA 2NTIA 2AWAA 1UD9A 3IFVA 1AXCA 1IZ5A 3FDSD 3P87A 3U5ZF 2IX2B 2IZOB 3A1JB 3P91A 3FDSC 2IX2A 5IWDA 1W60A 2HIKB 2ZVLA 2OD8A 3AIXB 1PLRA 3GGRB 1VYJA 3AIXA 5H0TA 5IXAA 3GPNA 3G65B 3LX2A 3G65A 1DMLA
chains in the Genus database with same CATH topology
2IJXA 1VYMA 4YHRA 1CZDA 2ZVKA 5E0UA 4D2GA 4CS5A 1GE8A 3U61F 4L60A 4TR6A 3VKXA 5B7OA 3A1JC 2IZOC 5JNED 2ZVMA 3I2MX 2HIKC 3AIZC 1YYPA 3GGRC 3V62B 5HACA 2HIIB 3HSLX 3WGWA 1IZ4A 2HIIA 1U7BA 4L6PA 5A6DA 1RXMA 2NTIC 1RXZA 5E0TA 5DAIA 1T6LA 2ZVWA 2IX2C 3P83A 2Z0LA 4ZTDA 3V60B 1B8HA 2IO4A 1RWZA 3K4XA 3HI8A 3G65C 3V61B 2AVTA 3U60F 3TBLA 1UL1A 3A2FB 3GPMA 3LX1A 1PLQA 3F1WA 3A1JA 5CFKA 1ISQA 2HIKA 3AIZA 3GGRA 2IO4B 5AUJA 1B77A 1SXJF 5E0VA 2ZVVA 4HK1A 2NTIB 5DA7A 2HIIC 5IY4A 1U76A 4RJFA 2NTIA 2AWAA 1UD9A 3IFVA 1AXCA 1IZ5A 3FDSD 3P87A 3U5ZF 2IX2B 2IZOB 3A1JB 3P91A 3FDSC 2IX2A 5IWDA 1W60A 2HIKB 2ZVLA 2OD8A 3AIXB 1PLRA 3GGRB 1VYJA 3AIXA 5H0TA 5IXAA 3GPNA 3G65B 3LX2A 3G65A 1DMLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IJX A;  1VYM A;  4YHR A;  1CZD A;  2ZVK A;  5E0U A;  4D2G A;  4CS5 A;  1GE8 A;  3U61 F;  4L60 A;  4TR6 A;  3VKX A;  5B7O A;  3A1J C;  2IZO C;  5JNE D;  2ZVM A;  3I2M X;  2HIK C;  3AIZ C;  1YYP A;  3GGR C;  3V62 B;  5HAC A;  2HII B;  3HSL X;  3WGW A;  1IZ4 A;  2HII A;  1U7B A;  4L6P A;  5A6D A;  1RXM A;  2NTI C;  1RXZ A;  5E0T A;  5DAI A;  1T6L A;  2ZVW A;  2IX2 C;  3P83 A;  2Z0L A;  4ZTD A;  3V60 B;  1B8H A;  2IO4 A;  1RWZ A;  3K4X A;  3HI8 A;  3G65 C;  3V61 B;  2AVT A;  3U60 F;  3TBL A;  1UL1 A;  3A2F B;  3GPM A;  3LX1 A;  1PLQ A;  3F1W A;  3A1J A;  5CFK A;  1ISQ A;  2HIK A;  3AIZ A;  3GGR A;  2IO4 B;  5AUJ A;  1B77 A;  1SXJ F;  5E0V A;  2ZVV A;  4HK1 A;  2NTI B;  5DA7 A;  2HII C;  5IY4 A;  1U76 A;  4RJF A;  2NTI A;  2AWA A;  1UD9 A;  3IFV A;  1AXC A;  1IZ5 A;  3FDS D;  3P87 A;  3U5Z F;  2IX2 B;  2IZO B;  3A1J B;  3P91 A;  3FDS C;  2IX2 A;  5IWD A;  1W60 A;  2HIK B;  2ZVL A;  2OD8 A;  3AIX B;  1PLR A;  3GGR B;  1VYJ A;  3AIX A;  5H0T A;  5IXA A;  3GPN A;  3G65 B;  3LX2 A;  3G65 A;  1DML A; 
#chains in the Genus database with same CATH topology
 2IJX A;  1VYM A;  4YHR A;  1CZD A;  2ZVK A;  5E0U A;  4D2G A;  4CS5 A;  1GE8 A;  3U61 F;  4L60 A;  4TR6 A;  3VKX A;  5B7O A;  3A1J C;  2IZO C;  5JNE D;  2ZVM A;  3I2M X;  2HIK C;  3AIZ C;  1YYP A;  3GGR C;  3V62 B;  5HAC A;  2HII B;  3HSL X;  3WGW A;  1IZ4 A;  2HII A;  1U7B A;  4L6P A;  5A6D A;  1RXM A;  2NTI C;  1RXZ A;  5E0T A;  5DAI A;  1T6L A;  2ZVW A;  2IX2 C;  3P83 A;  2Z0L A;  4ZTD A;  3V60 B;  1B8H A;  2IO4 A;  1RWZ A;  3K4X A;  3HI8 A;  3G65 C;  3V61 B;  2AVT A;  3U60 F;  3TBL A;  1UL1 A;  3A2F B;  3GPM A;  3LX1 A;  1PLQ A;  3F1W A;  3A1J A;  5CFK A;  1ISQ A;  2HIK A;  3AIZ A;  3GGR A;  2IO4 B;  5AUJ A;  1B77 A;  1SXJ F;  5E0V A;  2ZVV A;  4HK1 A;  2NTI B;  5DA7 A;  2HII C;  5IY4 A;  1U76 A;  4RJF A;  2NTI A;  2AWA A;  1UD9 A;  3IFV A;  1AXC A;  1IZ5 A;  3FDS D;  3P87 A;  3U5Z F;  2IX2 B;  2IZO B;  3A1J B;  3P91 A;  3FDS C;  2IX2 A;  5IWD A;  1W60 A;  2HIK B;  2ZVL A;  2OD8 A;  3AIX B;  1PLR A;  3GGR B;  1VYJ A;  3AIX A;  5H0T A;  5IXA A;  3GPN A;  3G65 B;  3LX2 A;  3G65 A;  1DML A; 
#chains in the Genus database with same CATH homology
 2IJX A;  1VYM A;  4YHR A;  1CZD A;  2ZVK A;  5E0U A;  4D2G A;  4CS5 A;  1GE8 A;  3U61 F;  4L60 A;  4TR6 A;  3VKX A;  5B7O A;  3A1J C;  2IZO C;  5JNE D;  2ZVM A;  3I2M X;  2HIK C;  3AIZ C;  1YYP A;  3GGR C;  3V62 B;  5HAC A;  2HII B;  3HSL X;  3WGW A;  1IZ4 A;  2HII A;  1U7B A;  4L6P A;  5A6D A;  1RXM A;  2NTI C;  1RXZ A;  5E0T A;  5DAI A;  1T6L A;  2ZVW A;  2IX2 C;  3P83 A;  2Z0L A;  4ZTD A;  3V60 B;  1B8H A;  2IO4 A;  1RWZ A;  3K4X A;  3HI8 A;  3G65 C;  3V61 B;  2AVT A;  3U60 F;  3TBL A;  1UL1 A;  3A2F B;  3GPM A;  3LX1 A;  1PLQ A;  3F1W A;  3A1J A;  5CFK A;  1ISQ A;  2HIK A;  3AIZ A;  3GGR A;  2IO4 B;  5AUJ A;  1B77 A;  1SXJ F;  5E0V A;  2ZVV A;  4HK1 A;  2NTI B;  5DA7 A;  2HII C;  5IY4 A;  1U76 A;  4RJF A;  2NTI A;  2AWA A;  1UD9 A;  3IFV A;  1AXC A;  1IZ5 A;  3FDS D;  3P87 A;  3U5Z F;  2IX2 B;  2IZO B;  3A1J B;  3P91 A;  3FDS C;  2IX2 A;  5IWD A;  1W60 A;  2HIK B;  2ZVL A;  2OD8 A;  3AIX B;  1PLR A;  3GGR B;  1VYJ A;  3AIX A;  5H0T A;  5IXA A;  3GPN A;  3G65 B;  3LX2 A;  3G65 A;  1DML A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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