2IO4A

Crystal structure of pcna12 dimer from sulfolobus solfataricus.
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
249
structure length
249
Chain Sequence
MVKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYSIDSPTSVKLDVSSVKKILSKASSKKATIELTETDSGLKIIIRDEKSGAKSTIYIKAEKGQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEAGEEGKRYVAFLMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGHMIFWIAPRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Sulfolobus solfataricus
molecule keywords DNA polymerase sliding clamp B
total genus 61
structure length 249
sequence length 249
chains with identical sequence C
ec nomenclature
pdb deposition date 2006-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2io4A01
1T6LA 3GGRC 2IJXA 3I2MX 2NTIC 3P91A 3F1WA 5B7OA 5IY4A 4HK1A 3V61B 2HIKB 2ZVKA 5E0TA 1IZ4A 3VKXA 5IWDA 2ZVWA 1W60A 2ZVVA 3G65A 1RXZA 1UD9A 5H0TA 1PLQA 2HIIB 4ZTDA 3AIZA 1U76A 3G65C 1YYPA 5HACA 1B8HA 2IZOC 3A1JA 2IX2C 3K4XA 3GGRB 2AWAA 3HSLX 3P83A 2IO4B 2OD8A 2NTIB 3U5ZF 3A1JC 4L6PA 3LX2A 1RWZA 1ISQA 1RXMA 3AIXA 4TR6A 4L60A 5E0VA 3V62B 1AXCA 5E0UA 3A2FB 2HIIA 1IZ5A 1U7BA 2ZVLA 3P87A 1CZDA 2ZVMA 3G65B 1VYMA 3AIZC 3GPMA 2IZOB 3GGRA 5IXAA 4D2GA 1DMLA 2IX2B 2HIKA 5DAIA 1SXJF 2AVTA 5AUJA 1PLRA 3WGWA 1GE8A 1UL1A 5DA7A 1VYJA 3FDSD 5A6DA 3A1JB 2HIKC 3U60F 3LX1A 3HI8A 2Z0LA 3TBLA 4RJFA 1B77A 5JNED 4YHRA 3AIXB 2HIIC 3GPNA 3V60B 3U61F 3IFVA 3FDSC 2IO4A 2NTIA 4CS5A 2IX2A 5CFKA
chains in the Genus database with same CATH superfamily
1T6LA 3GGRC 2IJXA 3I2MX 2NTIC 3P91A 3F1WA 5B7OA 5IY4A 4HK1A 3V61B 2HIKB 2ZVKA 5E0TA 1IZ4A 3VKXA 5IWDA 2ZVWA 1W60A 2ZVVA 3G65A 1RXZA 1UD9A 5H0TA 1PLQA 2HIIB 4ZTDA 3AIZA 1U76A 3G65C 1YYPA 5HACA 1B8HA 2IZOC 3A1JA 2IX2C 3K4XA 3GGRB 2AWAA 3HSLX 3P83A 2IO4B 2OD8A 2NTIB 3U5ZF 3A1JC 4L6PA 3LX2A 1RWZA 1ISQA 1RXMA 3AIXA 4TR6A 4L60A 5E0VA 3V62B 1AXCA 5E0UA 3A2FB 2HIIA 1IZ5A 1U7BA 2ZVLA 3P87A 1CZDA 2ZVMA 3G65B 1VYMA 3AIZC 3GPMA 2IZOB 3GGRA 5IXAA 4D2GA 1DMLA 2IX2B 2HIKA 5DAIA 1SXJF 2AVTA 5AUJA 1PLRA 3WGWA 1GE8A 1UL1A 5DA7A 1VYJA 3FDSD 5A6DA 3A1JB 2HIKC 3U60F 3LX1A 3HI8A 2Z0LA 3TBLA 4RJFA 1B77A 5JNED 4YHRA 3AIXB 2HIIC 3GPNA 3V60B 3U61F 3IFVA 3FDSC 2IO4A 2NTIA 4CS5A 2IX2A 5CFKA
chains in the Genus database with same CATH topology
1T6LA 3GGRC 2IJXA 3I2MX 2NTIC 3P91A 3F1WA 5B7OA 5IY4A 4HK1A 3V61B 2HIKB 2ZVKA 5E0TA 1IZ4A 3VKXA 5IWDA 2ZVWA 1W60A 2ZVVA 3G65A 1RXZA 1UD9A 5H0TA 1PLQA 2HIIB 4ZTDA 3AIZA 1U76A 3G65C 1YYPA 5HACA 1B8HA 2IZOC 3A1JA 2IX2C 3K4XA 3GGRB 2AWAA 3HSLX 3P83A 2IO4B 2OD8A 2NTIB 3U5ZF 3A1JC 4L6PA 3LX2A 1RWZA 1ISQA 1RXMA 3AIXA 4TR6A 4L60A 5E0VA 3V62B 1AXCA 5E0UA 3A2FB 2HIIA 1IZ5A 1U7BA 2ZVLA 3P87A 1CZDA 2ZVMA 3G65B 1VYMA 3AIZC 3GPMA 2IZOB 3GGRA 5IXAA 4D2GA 1DMLA 2IX2B 2HIKA 5DAIA 1SXJF 2AVTA 5AUJA 1PLRA 3WGWA 1GE8A 1UL1A 5DA7A 1VYJA 3FDSD 5A6DA 3A1JB 2HIKC 3U60F 3LX1A 3HI8A 2Z0LA 3TBLA 4RJFA 1B77A 5JNED 4YHRA 3AIXB 2HIIC 3GPNA 3V60B 3U61F 3IFVA 3FDSC 2IO4A 2NTIA 4CS5A 2IX2A 5CFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T6L A;  3GGR C;  2IJX A;  3I2M X;  2NTI C;  3P91 A;  3F1W A;  5B7O A;  5IY4 A;  4HK1 A;  3V61 B;  2HIK B;  2ZVK A;  5E0T A;  1IZ4 A;  3VKX A;  5IWD A;  2ZVW A;  1W60 A;  2ZVV A;  3G65 A;  1RXZ A;  1UD9 A;  5H0T A;  1PLQ A;  2HII B;  4ZTD A;  3AIZ A;  1U76 A;  3G65 C;  1YYP A;  5HAC A;  1B8H A;  2IZO C;  3A1J A;  2IX2 C;  3K4X A;  3GGR B;  2AWA A;  3HSL X;  3P83 A;  2IO4 B;  2OD8 A;  2NTI B;  3U5Z F;  3A1J C;  4L6P A;  3LX2 A;  1RWZ A;  1ISQ A;  1RXM A;  3AIX A;  4TR6 A;  4L60 A;  5E0V A;  3V62 B;  1AXC A;  5E0U A;  3A2F B;  2HII A;  1IZ5 A;  1U7B A;  2ZVL A;  3P87 A;  1CZD A;  2ZVM A;  3G65 B;  1VYM A;  3AIZ C;  3GPM A;  2IZO B;  3GGR A;  5IXA A;  4D2G A;  1DML A;  2IX2 B;  2HIK A;  5DAI A;  1SXJ F;  2AVT A;  5AUJ A;  1PLR A;  3WGW A;  1GE8 A;  1UL1 A;  5DA7 A;  1VYJ A;  3FDS D;  5A6D A;  3A1J B;  2HIK C;  3U60 F;  3LX1 A;  3HI8 A;  2Z0L A;  3TBL A;  4RJF A;  1B77 A;  5JNE D;  4YHR A;  3AIX B;  2HII C;  3GPN A;  3V60 B;  3U61 F;  3IFV A;  3FDS C;  2IO4 A;  2NTI A;  4CS5 A;  2IX2 A;  5CFK A; 
#chains in the Genus database with same CATH topology
 1T6L A;  3GGR C;  2IJX A;  3I2M X;  2NTI C;  3P91 A;  3F1W A;  5B7O A;  5IY4 A;  4HK1 A;  3V61 B;  2HIK B;  2ZVK A;  5E0T A;  1IZ4 A;  3VKX A;  5IWD A;  2ZVW A;  1W60 A;  2ZVV A;  3G65 A;  1RXZ A;  1UD9 A;  5H0T A;  1PLQ A;  2HII B;  4ZTD A;  3AIZ A;  1U76 A;  3G65 C;  1YYP A;  5HAC A;  1B8H A;  2IZO C;  3A1J A;  2IX2 C;  3K4X A;  3GGR B;  2AWA A;  3HSL X;  3P83 A;  2IO4 B;  2OD8 A;  2NTI B;  3U5Z F;  3A1J C;  4L6P A;  3LX2 A;  1RWZ A;  1ISQ A;  1RXM A;  3AIX A;  4TR6 A;  4L60 A;  5E0V A;  3V62 B;  1AXC A;  5E0U A;  3A2F B;  2HII A;  1IZ5 A;  1U7B A;  2ZVL A;  3P87 A;  1CZD A;  2ZVM A;  3G65 B;  1VYM A;  3AIZ C;  3GPM A;  2IZO B;  3GGR A;  5IXA A;  4D2G A;  1DML A;  2IX2 B;  2HIK A;  5DAI A;  1SXJ F;  2AVT A;  5AUJ A;  1PLR A;  3WGW A;  1GE8 A;  1UL1 A;  5DA7 A;  1VYJ A;  3FDS D;  5A6D A;  3A1J B;  2HIK C;  3U60 F;  3LX1 A;  3HI8 A;  2Z0L A;  3TBL A;  4RJF A;  1B77 A;  5JNE D;  4YHR A;  3AIX B;  2HII C;  3GPN A;  3V60 B;  3U61 F;  3IFV A;  3FDS C;  2IO4 A;  2NTI A;  4CS5 A;  2IX2 A;  5CFK A; 
#chains in the Genus database with same CATH homology
 1T6L A;  3GGR C;  2IJX A;  3I2M X;  2NTI C;  3P91 A;  3F1W A;  5B7O A;  5IY4 A;  4HK1 A;  3V61 B;  2HIK B;  2ZVK A;  5E0T A;  1IZ4 A;  3VKX A;  5IWD A;  2ZVW A;  1W60 A;  2ZVV A;  3G65 A;  1RXZ A;  1UD9 A;  5H0T A;  1PLQ A;  2HII B;  4ZTD A;  3AIZ A;  1U76 A;  3G65 C;  1YYP A;  5HAC A;  1B8H A;  2IZO C;  3A1J A;  2IX2 C;  3K4X A;  3GGR B;  2AWA A;  3HSL X;  3P83 A;  2IO4 B;  2OD8 A;  2NTI B;  3U5Z F;  3A1J C;  4L6P A;  3LX2 A;  1RWZ A;  1ISQ A;  1RXM A;  3AIX A;  4TR6 A;  4L60 A;  5E0V A;  3V62 B;  1AXC A;  5E0U A;  3A2F B;  2HII A;  1IZ5 A;  1U7B A;  2ZVL A;  3P87 A;  1CZD A;  2ZVM A;  3G65 B;  1VYM A;  3AIZ C;  3GPM A;  2IZO B;  3GGR A;  5IXA A;  4D2G A;  1DML A;  2IX2 B;  2HIK A;  5DAI A;  1SXJ F;  2AVT A;  5AUJ A;  1PLR A;  3WGW A;  1GE8 A;  1UL1 A;  5DA7 A;  1VYJ A;  3FDS D;  5A6D A;  3A1J B;  2HIK C;  3U60 F;  3LX1 A;  3HI8 A;  2Z0L A;  3TBL A;  4RJF A;  1B77 A;  5JNE D;  4YHR A;  3AIX B;  2HII C;  3GPN A;  3V60 B;  3U61 F;  3IFV A;  3FDS C;  2IO4 A;  2NTI A;  4CS5 A;  2IX2 A;  5CFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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