2NTIA

Crystal structure of pcna123 heterotrimer.
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
248
structure length
248
Chain Sequence
MVKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYSIDSPTSVKLDVSSVKKILSKASSKKATIELTETDSGLKIIIRDEKSGAKSTIYIKAEKGQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEAGEEGKRYVAFLMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGHMIFWIAPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
source organism Sulfolobus solfataricus
publication title Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
pubmed doi rcsb
molecule keywords DNA polymerase sliding clamp B
total genus 64
structure length 248
sequence length 248
chains with identical sequence D, G
ec nomenclature
pdb deposition date 2006-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2ntiA01
2ZVMA 1GE8A 4ZTDA 3GGRA 1UD9A 4YHRA 4L60A 5AUJA 3V60B 4HK1A 1PLQA 3LX2A 1PLRA 3F1WA 3GPNA 3P87A 3I2MX 1W60A 2AVTA 5HACA 3AIXB 1IZ4A 2AWAA 3AIZC 3GPMA 1AXCA 2ZVKA 1B8HA 3AIXA 3P83A 1T6LA 3AIZA 3TBLA 3WGWA 1RXZA 1RXMA 5JNED 5IWDA 2IX2C 3U5ZF 2ZVLA 5IXAA 5CFKA 2IX2A 2ZVWA 5H0TA 2HIIC 1RWZA 1U7BA 3U60F 5B7OA 5DA7A 2ZVVA 3HSLX 1VYJA 5E0VA 3K4XA 5DAIA 4TR6A 5E0TA 3A1JC 3A1JB 2OD8A 3IFVA 1SXJF 3G65C 3A1JA 3G65B 1U76A 1VYMA 3U61F 2IJXA 2IX2B 2IO4B 3G65A 1ISQA 3FDSD 1UL1A 2IO4A 2HIIB 5E0UA 5A6DA 4D2GA 2HIIA 3FDSC 3HI8A 4RJFA 1YYPA 3LX1A 1B77A 1CZDA 3V62B 3P91A 4L6PA 2NTIC 1IZ5A 2NTIB 2HIKC 2HIKB 3VKXA 2Z0LA 2NTIA 3V61B 2IZOC 2HIKA 2IZOB 3A2FB 1DMLA 4CS5A 3GGRC 5IY4A 3GGRB
chains in the Genus database with same CATH superfamily
2ZVMA 1GE8A 4ZTDA 3GGRA 1UD9A 4YHRA 4L60A 5AUJA 3V60B 4HK1A 1PLQA 3LX2A 1PLRA 3F1WA 3GPNA 3P87A 3I2MX 1W60A 2AVTA 5HACA 3AIXB 1IZ4A 2AWAA 3AIZC 3GPMA 1AXCA 2ZVKA 1B8HA 3AIXA 3P83A 1T6LA 3AIZA 3TBLA 3WGWA 1RXZA 1RXMA 5JNED 5IWDA 2IX2C 3U5ZF 2ZVLA 5IXAA 5CFKA 2IX2A 2ZVWA 5H0TA 2HIIC 1RWZA 1U7BA 3U60F 5B7OA 5DA7A 2ZVVA 3HSLX 1VYJA 5E0VA 3K4XA 5DAIA 4TR6A 5E0TA 3A1JC 3A1JB 2OD8A 3IFVA 1SXJF 3G65C 3A1JA 3G65B 1U76A 1VYMA 3U61F 2IJXA 2IX2B 2IO4B 3G65A 1ISQA 3FDSD 1UL1A 2IO4A 2HIIB 5E0UA 5A6DA 4D2GA 2HIIA 3FDSC 3HI8A 4RJFA 1YYPA 3LX1A 1B77A 1CZDA 3V62B 3P91A 4L6PA 2NTIC 1IZ5A 2NTIB 2HIKC 2HIKB 3VKXA 2Z0LA 2NTIA 3V61B 2IZOC 2HIKA 2IZOB 3A2FB 1DMLA 4CS5A 3GGRC 5IY4A 3GGRB
chains in the Genus database with same CATH topology
2ZVMA 1GE8A 4ZTDA 3GGRA 1UD9A 4YHRA 4L60A 5AUJA 3V60B 4HK1A 1PLQA 3LX2A 1PLRA 3F1WA 3GPNA 3P87A 3I2MX 1W60A 2AVTA 5HACA 3AIXB 1IZ4A 2AWAA 3AIZC 3GPMA 1AXCA 2ZVKA 1B8HA 3AIXA 3P83A 1T6LA 3AIZA 3TBLA 3WGWA 1RXZA 1RXMA 5JNED 5IWDA 2IX2C 3U5ZF 2ZVLA 5IXAA 5CFKA 2IX2A 2ZVWA 5H0TA 2HIIC 1RWZA 1U7BA 3U60F 5B7OA 5DA7A 2ZVVA 3HSLX 1VYJA 5E0VA 3K4XA 5DAIA 4TR6A 5E0TA 3A1JC 3A1JB 2OD8A 3IFVA 1SXJF 3G65C 3A1JA 3G65B 1U76A 1VYMA 3U61F 2IJXA 2IX2B 2IO4B 3G65A 1ISQA 3FDSD 1UL1A 2IO4A 2HIIB 5E0UA 5A6DA 4D2GA 2HIIA 3FDSC 3HI8A 4RJFA 1YYPA 3LX1A 1B77A 1CZDA 3V62B 3P91A 4L6PA 2NTIC 1IZ5A 2NTIB 2HIKC 2HIKB 3VKXA 2Z0LA 2NTIA 3V61B 2IZOC 2HIKA 2IZOB 3A2FB 1DMLA 4CS5A 3GGRC 5IY4A 3GGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVM A;  1GE8 A;  4ZTD A;  3GGR A;  1UD9 A;  4YHR A;  4L60 A;  5AUJ A;  3V60 B;  4HK1 A;  1PLQ A;  3LX2 A;  1PLR A;  3F1W A;  3GPN A;  3P87 A;  3I2M X;  1W60 A;  2AVT A;  5HAC A;  3AIX B;  1IZ4 A;  2AWA A;  3AIZ C;  3GPM A;  1AXC A;  2ZVK A;  1B8H A;  3AIX A;  3P83 A;  1T6L A;  3AIZ A;  3TBL A;  3WGW A;  1RXZ A;  1RXM A;  5JNE D;  5IWD A;  2IX2 C;  3U5Z F;  2ZVL A;  5IXA A;  5CFK A;  2IX2 A;  2ZVW A;  5H0T A;  2HII C;  1RWZ A;  1U7B A;  3U60 F;  5B7O A;  5DA7 A;  2ZVV A;  3HSL X;  1VYJ A;  5E0V A;  3K4X A;  5DAI A;  4TR6 A;  5E0T A;  3A1J C;  3A1J B;  2OD8 A;  3IFV A;  1SXJ F;  3G65 C;  3A1J A;  3G65 B;  1U76 A;  1VYM A;  3U61 F;  2IJX A;  2IX2 B;  2IO4 B;  3G65 A;  1ISQ A;  3FDS D;  1UL1 A;  2IO4 A;  2HII B;  5E0U A;  5A6D A;  4D2G A;  2HII A;  3FDS C;  3HI8 A;  4RJF A;  1YYP A;  3LX1 A;  1B77 A;  1CZD A;  3V62 B;  3P91 A;  4L6P A;  2NTI C;  1IZ5 A;  2NTI B;  2HIK C;  2HIK B;  3VKX A;  2Z0L A;  2NTI A;  3V61 B;  2IZO C;  2HIK A;  2IZO B;  3A2F B;  1DML A;  4CS5 A;  3GGR C;  5IY4 A;  3GGR B; 
#chains in the Genus database with same CATH topology
 2ZVM A;  1GE8 A;  4ZTD A;  3GGR A;  1UD9 A;  4YHR A;  4L60 A;  5AUJ A;  3V60 B;  4HK1 A;  1PLQ A;  3LX2 A;  1PLR A;  3F1W A;  3GPN A;  3P87 A;  3I2M X;  1W60 A;  2AVT A;  5HAC A;  3AIX B;  1IZ4 A;  2AWA A;  3AIZ C;  3GPM A;  1AXC A;  2ZVK A;  1B8H A;  3AIX A;  3P83 A;  1T6L A;  3AIZ A;  3TBL A;  3WGW A;  1RXZ A;  1RXM A;  5JNE D;  5IWD A;  2IX2 C;  3U5Z F;  2ZVL A;  5IXA A;  5CFK A;  2IX2 A;  2ZVW A;  5H0T A;  2HII C;  1RWZ A;  1U7B A;  3U60 F;  5B7O A;  5DA7 A;  2ZVV A;  3HSL X;  1VYJ A;  5E0V A;  3K4X A;  5DAI A;  4TR6 A;  5E0T A;  3A1J C;  3A1J B;  2OD8 A;  3IFV A;  1SXJ F;  3G65 C;  3A1J A;  3G65 B;  1U76 A;  1VYM A;  3U61 F;  2IJX A;  2IX2 B;  2IO4 B;  3G65 A;  1ISQ A;  3FDS D;  1UL1 A;  2IO4 A;  2HII B;  5E0U A;  5A6D A;  4D2G A;  2HII A;  3FDS C;  3HI8 A;  4RJF A;  1YYP A;  3LX1 A;  1B77 A;  1CZD A;  3V62 B;  3P91 A;  4L6P A;  2NTI C;  1IZ5 A;  2NTI B;  2HIK C;  2HIK B;  3VKX A;  2Z0L A;  2NTI A;  3V61 B;  2IZO C;  2HIK A;  2IZO B;  3A2F B;  1DML A;  4CS5 A;  3GGR C;  5IY4 A;  3GGR B; 
#chains in the Genus database with same CATH homology
 2ZVM A;  1GE8 A;  4ZTD A;  3GGR A;  1UD9 A;  4YHR A;  4L60 A;  5AUJ A;  3V60 B;  4HK1 A;  1PLQ A;  3LX2 A;  1PLR A;  3F1W A;  3GPN A;  3P87 A;  3I2M X;  1W60 A;  2AVT A;  5HAC A;  3AIX B;  1IZ4 A;  2AWA A;  3AIZ C;  3GPM A;  1AXC A;  2ZVK A;  1B8H A;  3AIX A;  3P83 A;  1T6L A;  3AIZ A;  3TBL A;  3WGW A;  1RXZ A;  1RXM A;  5JNE D;  5IWD A;  2IX2 C;  3U5Z F;  2ZVL A;  5IXA A;  5CFK A;  2IX2 A;  2ZVW A;  5H0T A;  2HII C;  1RWZ A;  1U7B A;  3U60 F;  5B7O A;  5DA7 A;  2ZVV A;  3HSL X;  1VYJ A;  5E0V A;  3K4X A;  5DAI A;  4TR6 A;  5E0T A;  3A1J C;  3A1J B;  2OD8 A;  3IFV A;  1SXJ F;  3G65 C;  3A1J A;  3G65 B;  1U76 A;  1VYM A;  3U61 F;  2IJX A;  2IX2 B;  2IO4 B;  3G65 A;  1ISQ A;  3FDS D;  1UL1 A;  2IO4 A;  2HII B;  5E0U A;  5A6D A;  4D2G A;  2HII A;  3FDS C;  3HI8 A;  4RJF A;  1YYP A;  3LX1 A;  1B77 A;  1CZD A;  3V62 B;  3P91 A;  4L6P A;  2NTI C;  1IZ5 A;  2NTI B;  2HIK C;  2HIK B;  3VKX A;  2Z0L A;  2NTI A;  3V61 B;  2IZO C;  2HIK A;  2IZO B;  3A2F B;  1DML A;  4CS5 A;  3GGR C;  5IY4 A;  3GGR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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