3GPNA

Structure of the non-trimeric form of the e113g pcna mutant protein
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
253
structure length
253
Chain Sequence
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAGYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Saccharomyces cerevisiae
molecule keywords Proliferating cell nuclear antigen
total genus 57
structure length 253
sequence length 253
ec nomenclature
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3gpnA00
3FDSC 2ZVWA 1RXZA 2IJXA 5E0VA 3A1JB 3AIXA 3P83A 2IX2B 4L60A 3A1JC 2HIKA 2Z0LA 2IZOB 5HACA 3A1JA 1PLRA 3WGWA 2IX2A 3IFVA 1DMLA 3HSLX 4L6PA 3LX2A 2IO4B 1T6LA 3I2MX 2HIKC 1GE8A 1W60A 1VYMA 3GGRB 3GPMA 3P91A 2AWAA 5E0TA 1U76A 3G65B 4YHRA 4D2GA 1UD9A 2IX2C 2IO4A 3GGRC 5B7OA 2ZVLA 1SXJF 2ZVMA 3G65C 2OD8A 1ISQA 5DAIA 2IZOC 3P87A 1YYPA 3GGRA 3TBLA 1RXMA 3G65A 3K4XA 3FDSD 4CS5A 4RJFA 1U7BA 3GPNA 1B8HA 5IY4A 3F1WA 5CFKA 3U5ZF 1VYJA 1B77A 4ZTDA 5H0TA 4TR6A 3A2FB 2HIIB 3U61F 3LX1A 5E0UA 5IWDA 1AXCA 2NTIB 5DA7A 2HIIC 3U60F 1UL1A 1CZDA 5A6DA 2NTIC 5JNED 3AIZC 2ZVKA 2HIIA 1IZ4A 5AUJA 4HK1A 2ZVVA 5IXAA 1IZ5A 3AIXB 2NTIA 3V60B 1RWZA 3AIZA 3V61B 2AVTA 3HI8A 3VKXA 3V62B 1PLQA 2HIKB
chains in the Genus database with same CATH superfamily
3FDSC 2ZVWA 1RXZA 2IJXA 5E0VA 3A1JB 3AIXA 3P83A 2IX2B 4L60A 3A1JC 2HIKA 2Z0LA 2IZOB 5HACA 3A1JA 1PLRA 3WGWA 2IX2A 3IFVA 1DMLA 3HSLX 4L6PA 3LX2A 2IO4B 1T6LA 3I2MX 2HIKC 1GE8A 1W60A 1VYMA 3GGRB 3GPMA 3P91A 2AWAA 5E0TA 1U76A 3G65B 4YHRA 4D2GA 1UD9A 2IX2C 2IO4A 3GGRC 5B7OA 2ZVLA 1SXJF 2ZVMA 3G65C 2OD8A 1ISQA 5DAIA 2IZOC 3P87A 1YYPA 3GGRA 3TBLA 1RXMA 3G65A 3K4XA 3FDSD 4CS5A 4RJFA 1U7BA 3GPNA 1B8HA 5IY4A 3F1WA 5CFKA 3U5ZF 1VYJA 1B77A 4ZTDA 5H0TA 4TR6A 3A2FB 2HIIB 3U61F 3LX1A 5E0UA 5IWDA 1AXCA 2NTIB 5DA7A 2HIIC 3U60F 1UL1A 1CZDA 5A6DA 2NTIC 5JNED 3AIZC 2ZVKA 2HIIA 1IZ4A 5AUJA 4HK1A 2ZVVA 5IXAA 1IZ5A 3AIXB 2NTIA 3V60B 1RWZA 3AIZA 3V61B 2AVTA 3HI8A 3VKXA 3V62B 1PLQA 2HIKB
chains in the Genus database with same CATH topology
3FDSC 2ZVWA 1RXZA 2IJXA 5E0VA 3A1JB 3AIXA 3P83A 2IX2B 4L60A 3A1JC 2HIKA 2Z0LA 2IZOB 5HACA 3A1JA 1PLRA 3WGWA 2IX2A 3IFVA 1DMLA 3HSLX 4L6PA 3LX2A 2IO4B 1T6LA 3I2MX 2HIKC 1GE8A 1W60A 1VYMA 3GGRB 3GPMA 3P91A 2AWAA 5E0TA 1U76A 3G65B 4YHRA 4D2GA 1UD9A 2IX2C 2IO4A 3GGRC 5B7OA 2ZVLA 1SXJF 2ZVMA 3G65C 2OD8A 1ISQA 5DAIA 2IZOC 3P87A 1YYPA 3GGRA 3TBLA 1RXMA 3G65A 3K4XA 3FDSD 4CS5A 4RJFA 1U7BA 3GPNA 1B8HA 5IY4A 3F1WA 5CFKA 3U5ZF 1VYJA 1B77A 4ZTDA 5H0TA 4TR6A 3A2FB 2HIIB 3U61F 3LX1A 5E0UA 5IWDA 1AXCA 2NTIB 5DA7A 2HIIC 3U60F 1UL1A 1CZDA 5A6DA 2NTIC 5JNED 3AIZC 2ZVKA 2HIIA 1IZ4A 5AUJA 4HK1A 2ZVVA 5IXAA 1IZ5A 3AIXB 2NTIA 3V60B 1RWZA 3AIZA 3V61B 2AVTA 3HI8A 3VKXA 3V62B 1PLQA 2HIKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FDS C;  2ZVW A;  1RXZ A;  2IJX A;  5E0V A;  3A1J B;  3AIX A;  3P83 A;  2IX2 B;  4L60 A;  3A1J C;  2HIK A;  2Z0L A;  2IZO B;  5HAC A;  3A1J A;  1PLR A;  3WGW A;  2IX2 A;  3IFV A;  1DML A;  3HSL X;  4L6P A;  3LX2 A;  2IO4 B;  1T6L A;  3I2M X;  2HIK C;  1GE8 A;  1W60 A;  1VYM A;  3GGR B;  3GPM A;  3P91 A;  2AWA A;  5E0T A;  1U76 A;  3G65 B;  4YHR A;  4D2G A;  1UD9 A;  2IX2 C;  2IO4 A;  3GGR C;  5B7O A;  2ZVL A;  1SXJ F;  2ZVM A;  3G65 C;  2OD8 A;  1ISQ A;  5DAI A;  2IZO C;  3P87 A;  1YYP A;  3GGR A;  3TBL A;  1RXM A;  3G65 A;  3K4X A;  3FDS D;  4CS5 A;  4RJF A;  1U7B A;  3GPN A;  1B8H A;  5IY4 A;  3F1W A;  5CFK A;  3U5Z F;  1VYJ A;  1B77 A;  4ZTD A;  5H0T A;  4TR6 A;  3A2F B;  2HII B;  3U61 F;  3LX1 A;  5E0U A;  5IWD A;  1AXC A;  2NTI B;  5DA7 A;  2HII C;  3U60 F;  1UL1 A;  1CZD A;  5A6D A;  2NTI C;  5JNE D;  3AIZ C;  2ZVK A;  2HII A;  1IZ4 A;  5AUJ A;  4HK1 A;  2ZVV A;  5IXA A;  1IZ5 A;  3AIX B;  2NTI A;  3V60 B;  1RWZ A;  3AIZ A;  3V61 B;  2AVT A;  3HI8 A;  3VKX A;  3V62 B;  1PLQ A;  2HIK B; 
#chains in the Genus database with same CATH topology
 3FDS C;  2ZVW A;  1RXZ A;  2IJX A;  5E0V A;  3A1J B;  3AIX A;  3P83 A;  2IX2 B;  4L60 A;  3A1J C;  2HIK A;  2Z0L A;  2IZO B;  5HAC A;  3A1J A;  1PLR A;  3WGW A;  2IX2 A;  3IFV A;  1DML A;  3HSL X;  4L6P A;  3LX2 A;  2IO4 B;  1T6L A;  3I2M X;  2HIK C;  1GE8 A;  1W60 A;  1VYM A;  3GGR B;  3GPM A;  3P91 A;  2AWA A;  5E0T A;  1U76 A;  3G65 B;  4YHR A;  4D2G A;  1UD9 A;  2IX2 C;  2IO4 A;  3GGR C;  5B7O A;  2ZVL A;  1SXJ F;  2ZVM A;  3G65 C;  2OD8 A;  1ISQ A;  5DAI A;  2IZO C;  3P87 A;  1YYP A;  3GGR A;  3TBL A;  1RXM A;  3G65 A;  3K4X A;  3FDS D;  4CS5 A;  4RJF A;  1U7B A;  3GPN A;  1B8H A;  5IY4 A;  3F1W A;  5CFK A;  3U5Z F;  1VYJ A;  1B77 A;  4ZTD A;  5H0T A;  4TR6 A;  3A2F B;  2HII B;  3U61 F;  3LX1 A;  5E0U A;  5IWD A;  1AXC A;  2NTI B;  5DA7 A;  2HII C;  3U60 F;  1UL1 A;  1CZD A;  5A6D A;  2NTI C;  5JNE D;  3AIZ C;  2ZVK A;  2HII A;  1IZ4 A;  5AUJ A;  4HK1 A;  2ZVV A;  5IXA A;  1IZ5 A;  3AIX B;  2NTI A;  3V60 B;  1RWZ A;  3AIZ A;  3V61 B;  2AVT A;  3HI8 A;  3VKX A;  3V62 B;  1PLQ A;  2HIK B; 
#chains in the Genus database with same CATH homology
 3FDS C;  2ZVW A;  1RXZ A;  2IJX A;  5E0V A;  3A1J B;  3AIX A;  3P83 A;  2IX2 B;  4L60 A;  3A1J C;  2HIK A;  2Z0L A;  2IZO B;  5HAC A;  3A1J A;  1PLR A;  3WGW A;  2IX2 A;  3IFV A;  1DML A;  3HSL X;  4L6P A;  3LX2 A;  2IO4 B;  1T6L A;  3I2M X;  2HIK C;  1GE8 A;  1W60 A;  1VYM A;  3GGR B;  3GPM A;  3P91 A;  2AWA A;  5E0T A;  1U76 A;  3G65 B;  4YHR A;  4D2G A;  1UD9 A;  2IX2 C;  2IO4 A;  3GGR C;  5B7O A;  2ZVL A;  1SXJ F;  2ZVM A;  3G65 C;  2OD8 A;  1ISQ A;  5DAI A;  2IZO C;  3P87 A;  1YYP A;  3GGR A;  3TBL A;  1RXM A;  3G65 A;  3K4X A;  3FDS D;  4CS5 A;  4RJF A;  1U7B A;  3GPN A;  1B8H A;  5IY4 A;  3F1W A;  5CFK A;  3U5Z F;  1VYJ A;  1B77 A;  4ZTD A;  5H0T A;  4TR6 A;  3A2F B;  2HII B;  3U61 F;  3LX1 A;  5E0U A;  5IWD A;  1AXC A;  2NTI B;  5DA7 A;  2HII C;  3U60 F;  1UL1 A;  1CZD A;  5A6D A;  2NTI C;  5JNE D;  3AIZ C;  2ZVK A;  2HII A;  1IZ4 A;  5AUJ A;  4HK1 A;  2ZVV A;  5IXA A;  1IZ5 A;  3AIX B;  2NTI A;  3V60 B;  1RWZ A;  3AIZ A;  3V61 B;  2AVT A;  3HI8 A;  3VKX A;  3V62 B;  1PLQ A;  2HIK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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