3O3IX

Crystal structure of human hiwi1 paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2'-oh at its 3'-end
Total Genus 21
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
118
structure length
108
Chain Sequence
SETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKGPAMLIPELCYLTGLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords Piwi-like protein 1
total genus 21
structure length 108
sequence length 118
ec nomenclature
pdb deposition date 2010-07-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 3o3iX00
3QIRA 5KI6A 1T2RA 4Z4HA 1VYNA 4NGDA 3MJ0A 4Z4EA 4KREA 4Z4FA 4F3TA 2L5DA 4NGFA 4NGBA 4NH6A 3O6EX 4OLBA 4W5RA 1R6ZA 2FFLA 4W5OA 4NH5A 4W5QA 4OLAA 4Z4IA 4W5TA 4KRFA 5T7BA 4Z4GA 1R4KA 3O7XA 2QVWA 4Z4CA 2XFMA 3O3IX 4NGGA 3O7VX 1SI3A 4NGCA 5JS2A 1SI2A 4NH3A 5JS1A 1T2SA 4NHAA 4W5NA 2L5CA
chains in the Genus database with same CATH superfamily
3QIRA 1U04A 3DLHA 5KI6A 1T2RA 4Z4HA 3HJFA 3HO1A 1VYNA 1Z26A 4NGDA 3MJ0A 4W5NA 3U1UA 3HVRA 4Z4EA 4KREA 4Z4FA 4F3TA 2L5DA 4NGFA 4NGBA 4NH6A 3O6EX 2BZEA 4OLBA 1Z25A 4W5RA 1R6ZA 2FFLA 4W5OA 4NH5A 2DB9A 4W5QA 3HM9A 3HK2A 4OLAA 4Z4IA 4W5TA 4KRFA 5T7BA 4Z4GA 1R4KA 3O7XA 2QVWA 4Z4CA 2XFMA 3O3IX 4NGGA 4L1PA 3O7VX 1SI3A 4NGCA 5JS2A 1SI2A 4NH3A 3DLBA 3F73A 5JS1A 1T2SA 4NHAA 4L1UA 2L5CA 3DA5A
chains in the Genus database with same CATH topology
3QIRA 1U04A 3DLHA 5KI6A 1T2RA 4Z4HA 3HJFA 3HO1A 1VYNA 1Z26A 4NGDA 3MJ0A 4W5NA 3U1UA 3HVRA 4Z4EA 4KREA 4Z4FA 4F3TA 2L5DA 4NGFA 4NGBA 4NH6A 3O6EX 2BZEA 4OLBA 1Z25A 4W5RA 1R6ZA 2FFLA 4W5OA 4NH5A 2DB9A 4W5QA 3HM9A 3HK2A 4OLAA 4Z4IA 4W5TA 4KRFA 5T7BA 4Z4GA 1R4KA 3O7XA 2QVWA 4Z4CA 2XFMA 3O3IX 4NGGA 4L1PA 3O7VX 1SI3A 4NGCA 5JS2A 1SI2A 4NH3A 3DLBA 3F73A 5JS1A 1T2SA 4NHAA 4L1UA 2L5CA 3DA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QIR A;  5KI6 A;  1T2R A;  4Z4H A;  1VYN A;  4NGD A;  3MJ0 A;  4Z4E A;  4KRE A;  4Z4F A;  4F3T A;  2L5D A;  4NGF A;  4NGB A;  4NH6 A;  3O6E X;  4OLB A;  4W5R A;  1R6Z A;  2FFL A;  4W5O A;  4NH5 A;  4W5Q A;  4OLA A;  4Z4I A;  4W5T A;  4KRF A;  5T7B A;  4Z4G A;  1R4K A;  3O7X A;  2QVW A;  4Z4C A;  2XFM A;  3O3I X;  4NGG A;  3O7V X;  1SI3 A;  4NGC A;  5JS2 A;  1SI2 A;  4NH3 A;  5JS1 A;  1T2S A;  4NHA A;  4W5N A;  2L5C A; 
#chains in the Genus database with same CATH topology
 3QIR A;  1U04 A;  3DLH A;  5KI6 A;  1T2R A;  4Z4H A;  3HJF A;  3HO1 A;  1VYN A;  1Z26 A;  4NGD A;  3MJ0 A;  4W5N A;  3U1U A;  3HVR A;  4Z4E A;  4KRE A;  4Z4F A;  4F3T A;  2L5D A;  4NGF A;  4NGB A;  4NH6 A;  3O6E X;  2BZE A;  4OLB A;  1Z25 A;  4W5R A;  1R6Z A;  2FFL A;  4W5O A;  4NH5 A;  2DB9 A;  4W5Q A;  3HM9 A;  3HK2 A;  4OLA A;  4Z4I A;  4W5T A;  4KRF A;  5T7B A;  4Z4G A;  1R4K A;  3O7X A;  2QVW A;  4Z4C A;  2XFM A;  3O3I X;  4NGG A;  4L1P A;  3O7V X;  1SI3 A;  4NGC A;  5JS2 A;  1SI2 A;  4NH3 A;  3DLB A;  3F73 A;  5JS1 A;  1T2S A;  4NHA A;  4L1U A;  2L5C A;  3DA5 A; 
#chains in the Genus database with same CATH homology
 3QIR A;  1U04 A;  3DLH A;  5KI6 A;  1T2R A;  4Z4H A;  3HJF A;  3HO1 A;  1VYN A;  1Z26 A;  4NGD A;  3MJ0 A;  4W5N A;  3U1U A;  3HVR A;  4Z4E A;  4KRE A;  4Z4F A;  4F3T A;  2L5D A;  4NGF A;  4NGB A;  4NH6 A;  3O6E X;  2BZE A;  4OLB A;  1Z25 A;  4W5R A;  1R6Z A;  2FFL A;  4W5O A;  4NH5 A;  2DB9 A;  4W5Q A;  3HM9 A;  3HK2 A;  4OLA A;  4Z4I A;  4W5T A;  4KRF A;  5T7B A;  4Z4G A;  1R4K A;  3O7X A;  2QVW A;  4Z4C A;  2XFM A;  3O3I X;  4NGG A;  4L1P A;  3O7V X;  1SI3 A;  4NGC A;  5JS2 A;  1SI2 A;  4NH3 A;  3DLB A;  3F73 A;  5JS1 A;  1T2S A;  4NHA A;  4L1U A;  2L5C A;  3DA5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...