3O3IX

Crystal structure of human hiwi1 paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2'-oh at its 3'-end
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
118
structure length
108
Chain Sequence
SETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKGPAMLIPELCYLTGLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords Piwi-like protein 1
total genus 21
structure length 108
sequence length 118
ec nomenclature
pdb deposition date 2010-07-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 3o3iX00
2XFMA 4NGGA 2L5DA 4NGCA 4KREA 4NGBA 4Z4FA 4Z4IA 4NGDA 4W5RA 4OLAA 4W5QA 3O6EX 4KRFA 3MJ0A 3O7VX 4W5OA 1R4KA 3QIRA 2QVWA 2FFLA 4NH6A 4Z4EA 4F3TA 5T7BA 1T2RA 1SI3A 4W5NA 1VYNA 4NH3A 1R6ZA 3O7XA 5KI6A 4W5TA 3O3IX 4Z4GA 4NH5A 5JS1A 4NGFA 5JS2A 1T2SA 4OLBA 4NHAA 1SI2A 4Z4CA 2L5CA 4Z4HA
chains in the Genus database with same CATH superfamily
3DLBA 2XFMA 4NGGA 2L5DA 4NGCA 4KREA 3F73A 4NGBA 4Z4FA 4Z4IA 3HM9A 3HJFA 4NGDA 4W5RA 3DA5A 4W5QA 4OLAA 3O6EX 4KRFA 3MJ0A 3O7VX 3HO1A 2DB9A 4W5OA 1R4KA 3QIRA 2QVWA 2FFLA 4NH6A 1Z26A 4Z4EA 1Z25A 4F3TA 5T7BA 1T2RA 3HVRA 1SI3A 4W5NA 3HK2A 1VYNA 3DLHA 4NH3A 3U1UA 1R6ZA 3O7XA 5KI6A 4W5TA 3O3IX 2BZEA 4Z4GA 4NH5A 5JS1A 4L1PA 4NGFA 5JS2A 4L1UA 1T2SA 4OLBA 4NHAA 1SI2A 4Z4CA 2L5CA 1U04A 4Z4HA
chains in the Genus database with same CATH topology
3DLBA 2XFMA 4NGGA 2L5DA 4NGCA 4KREA 3F73A 4NGBA 4Z4FA 4Z4IA 3HM9A 3HJFA 4NGDA 4W5RA 3DA5A 4W5QA 4OLAA 3O6EX 4KRFA 3MJ0A 3O7VX 3HO1A 2DB9A 4W5OA 1R4KA 3QIRA 2QVWA 2FFLA 4NH6A 1Z26A 4Z4EA 1Z25A 4F3TA 5T7BA 1T2RA 3HVRA 1SI3A 4W5NA 3HK2A 1VYNA 3DLHA 4NH3A 3U1UA 1R6ZA 3O7XA 5KI6A 4W5TA 3O3IX 2BZEA 4Z4GA 4NH5A 5JS1A 4L1PA 4NGFA 5JS2A 4L1UA 1T2SA 4OLBA 4NHAA 1SI2A 4Z4CA 2L5CA 1U04A 4Z4HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XFM A;  4NGG A;  2L5D A;  4NGC A;  4KRE A;  4NGB A;  4Z4F A;  4Z4I A;  4NGD A;  4W5R A;  4OLA A;  4W5Q A;  3O6E X;  4KRF A;  3MJ0 A;  3O7V X;  4W5O A;  1R4K A;  3QIR A;  2QVW A;  2FFL A;  4NH6 A;  4Z4E A;  4F3T A;  5T7B A;  1T2R A;  1SI3 A;  4W5N A;  1VYN A;  4NH3 A;  1R6Z A;  3O7X A;  5KI6 A;  4W5T A;  3O3I X;  4Z4G A;  4NH5 A;  5JS1 A;  4NGF A;  5JS2 A;  1T2S A;  4OLB A;  4NHA A;  1SI2 A;  4Z4C A;  2L5C A;  4Z4H A; 
#chains in the Genus database with same CATH topology
 3DLB A;  2XFM A;  4NGG A;  2L5D A;  4NGC A;  4KRE A;  3F73 A;  4NGB A;  4Z4F A;  4Z4I A;  3HM9 A;  3HJF A;  4NGD A;  4W5R A;  3DA5 A;  4W5Q A;  4OLA A;  3O6E X;  4KRF A;  3MJ0 A;  3O7V X;  3HO1 A;  2DB9 A;  4W5O A;  1R4K A;  3QIR A;  2QVW A;  2FFL A;  4NH6 A;  1Z26 A;  4Z4E A;  1Z25 A;  4F3T A;  5T7B A;  1T2R A;  3HVR A;  1SI3 A;  4W5N A;  3HK2 A;  1VYN A;  3DLH A;  4NH3 A;  3U1U A;  1R6Z A;  3O7X A;  5KI6 A;  4W5T A;  3O3I X;  2BZE A;  4Z4G A;  4NH5 A;  5JS1 A;  4L1P A;  4NGF A;  5JS2 A;  4L1U A;  1T2S A;  4OLB A;  4NHA A;  1SI2 A;  4Z4C A;  2L5C A;  1U04 A;  4Z4H A; 
#chains in the Genus database with same CATH homology
 3DLB A;  2XFM A;  4NGG A;  2L5D A;  4NGC A;  4KRE A;  3F73 A;  4NGB A;  4Z4F A;  4Z4I A;  3HM9 A;  3HJF A;  4NGD A;  4W5R A;  3DA5 A;  4W5Q A;  4OLA A;  3O6E X;  4KRF A;  3MJ0 A;  3O7V X;  3HO1 A;  2DB9 A;  4W5O A;  1R4K A;  3QIR A;  2QVW A;  2FFL A;  4NH6 A;  1Z26 A;  4Z4E A;  1Z25 A;  4F3T A;  5T7B A;  1T2R A;  3HVR A;  1SI3 A;  4W5N A;  3HK2 A;  1VYN A;  3DLH A;  4NH3 A;  3U1U A;  1R6Z A;  3O7X A;  5KI6 A;  4W5T A;  3O3I X;  2BZE A;  4Z4G A;  4NH5 A;  5JS1 A;  4L1P A;  4NGF A;  5JS2 A;  4L1U A;  1T2S A;  4OLB A;  4NHA A;  1SI2 A;  4Z4C A;  2L5C A;  1U04 A;  4Z4H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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