3O7VX

Crystal structure of human hiwi1 (v361m) paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2'-och3 at its 3'-end
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
117
structure length
107
Chain Sequence
ETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPMLVSQPKGPAMLIPELCYLTGLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords Piwi-like protein 1
total genus 22
structure length 107
sequence length 117
ec nomenclature
pdb deposition date 2010-08-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 3o7vX00
4Z4FA 1R4KA 1T2RA 3MJ0A 4NGDA 4KRFA 2L5CA 4Z4HA 4W5OA 2XFMA 4NH6A 5JS1A 2FFLA 4W5TA 4OLBA 5T7BA 4F3TA 4Z4EA 4NGFA 3O7VX 1SI2A 4NGBA 1T2SA 4NHAA 3O3IX 1R6ZA 1VYNA 4Z4GA 4Z4CA 3O7XA 2QVWA 2L5DA 4W5QA 1SI3A 5JS2A 3QIRA 5KI6A 3O6EX 4Z4IA 4OLAA 4KREA 4NGCA 4NH3A 4W5NA 4W5RA 4NGGA 4NH5A
chains in the Genus database with same CATH superfamily
4Z4FA 1R4KA 1T2RA 3MJ0A 4NGDA 4KRFA 2L5CA 4Z4HA 4W5OA 2XFMA 4NH6A 5JS1A 1Z26A 2FFLA 2DB9A 4W5TA 5T7BA 4OLBA 4F3TA 3U1UA 4Z4EA 4NGFA 3O7VX 1SI2A 4NGBA 3HVRA 4L1PA 1Z25A 1T2SA 4NHAA 2BZEA 3O3IX 3HO1A 1R6ZA 1VYNA 4Z4GA 3DLBA 3F73A 4Z4CA 3DLHA 3DA5A 3O7XA 3HK2A 2QVWA 2L5DA 4W5QA 1SI3A 5JS2A 3QIRA 5KI6A 3O6EX 4Z4IA 1U04A 4OLAA 4KREA 3HJFA 4NGCA 4NH3A 4W5NA 4W5RA 3HM9A 4NGGA 4NH5A 4L1UA
chains in the Genus database with same CATH topology
4Z4FA 1R4KA 1T2RA 3MJ0A 4NGDA 4KRFA 2L5CA 4Z4HA 4W5OA 2XFMA 4NH6A 5JS1A 1Z26A 2FFLA 2DB9A 4W5TA 5T7BA 4OLBA 4F3TA 3U1UA 4Z4EA 4NGFA 3O7VX 1SI2A 4NGBA 3HVRA 4L1PA 1Z25A 1T2SA 4NHAA 2BZEA 3O3IX 3HO1A 1R6ZA 1VYNA 4Z4GA 3DLBA 3F73A 4Z4CA 3DLHA 3DA5A 3O7XA 3HK2A 2QVWA 2L5DA 4W5QA 1SI3A 5JS2A 3QIRA 5KI6A 3O6EX 4Z4IA 1U04A 4OLAA 4KREA 3HJFA 4NGCA 4NH3A 4W5NA 4W5RA 3HM9A 4NGGA 4NH5A 4L1UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z4F A;  1R4K A;  1T2R A;  3MJ0 A;  4NGD A;  4KRF A;  2L5C A;  4Z4H A;  4W5O A;  2XFM A;  4NH6 A;  5JS1 A;  2FFL A;  4W5T A;  4OLB A;  5T7B A;  4F3T A;  4Z4E A;  4NGF A;  3O7V X;  1SI2 A;  4NGB A;  1T2S A;  4NHA A;  3O3I X;  1R6Z A;  1VYN A;  4Z4G A;  4Z4C A;  3O7X A;  2QVW A;  2L5D A;  4W5Q A;  1SI3 A;  5JS2 A;  3QIR A;  5KI6 A;  3O6E X;  4Z4I A;  4OLA A;  4KRE A;  4NGC A;  4NH3 A;  4W5N A;  4W5R A;  4NGG A;  4NH5 A; 
#chains in the Genus database with same CATH topology
 4Z4F A;  1R4K A;  1T2R A;  3MJ0 A;  4NGD A;  4KRF A;  2L5C A;  4Z4H A;  4W5O A;  2XFM A;  4NH6 A;  5JS1 A;  1Z26 A;  2FFL A;  2DB9 A;  4W5T A;  5T7B A;  4OLB A;  4F3T A;  3U1U A;  4Z4E A;  4NGF A;  3O7V X;  1SI2 A;  4NGB A;  3HVR A;  4L1P A;  1Z25 A;  1T2S A;  4NHA A;  2BZE A;  3O3I X;  3HO1 A;  1R6Z A;  1VYN A;  4Z4G A;  3DLB A;  3F73 A;  4Z4C A;  3DLH A;  3DA5 A;  3O7X A;  3HK2 A;  2QVW A;  2L5D A;  4W5Q A;  1SI3 A;  5JS2 A;  3QIR A;  5KI6 A;  3O6E X;  4Z4I A;  1U04 A;  4OLA A;  4KRE A;  3HJF A;  4NGC A;  4NH3 A;  4W5N A;  4W5R A;  3HM9 A;  4NGG A;  4NH5 A;  4L1U A; 
#chains in the Genus database with same CATH homology
 4Z4F A;  1R4K A;  1T2R A;  3MJ0 A;  4NGD A;  4KRF A;  2L5C A;  4Z4H A;  4W5O A;  2XFM A;  4NH6 A;  5JS1 A;  1Z26 A;  2FFL A;  2DB9 A;  4W5T A;  5T7B A;  4OLB A;  4F3T A;  3U1U A;  4Z4E A;  4NGF A;  3O7V X;  1SI2 A;  4NGB A;  3HVR A;  4L1P A;  1Z25 A;  1T2S A;  4NHA A;  2BZE A;  3O3I X;  3HO1 A;  1R6Z A;  1VYN A;  4Z4G A;  3DLB A;  3F73 A;  4Z4C A;  3DLH A;  3DA5 A;  3O7X A;  3HK2 A;  2QVW A;  2L5D A;  4W5Q A;  1SI3 A;  5JS2 A;  3QIR A;  5KI6 A;  3O6E X;  4Z4I A;  1U04 A;  4OLA A;  4KRE A;  3HJF A;  4NGC A;  4NH3 A;  4W5N A;  4W5R A;  3HM9 A;  4NGG A;  4NH5 A;  4L1U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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