3TBLA

Structure of mono-ubiquitinated pcna: implications for dna polymerase switching and okazaki fragment maturation
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
256
structure length
250
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation.
pubmed doi rcsb
molecule tags Replication
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 59
structure length 250
sequence length 256
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2011-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3tblA00
1VYMA 3I2MX 3U61F 2OD8A 2IZOC 1T6LA 3U5ZF 2IZOB 5JNED 5CFKA 5E0TA 5IXAA 4D2GA 2IX2C 2AVTA 2IX2B 3A1JB 5AUJA 3AIZA 1UD9A 3GPNA 2HIKB 3A1JA 2NTIA 4TR6A 3AIXB 1PLQA 5IY4A 3P91A 1CZDA 1RXMA 1AXCA 3GGRA 1W60A 1ISQA 3AIXA 3WGWA 1GE8A 3V60B 5E0VA 2ZVWA 4YHRA 2IO4B 3VKXA 4CS5A 3HSLX 1RXZA 2HIIC 2HIIB 1SXJF 3LX2A 1B8HA 5DA7A 2IX2A 2ZVKA 1DMLA 1IZ5A 2ZVMA 2HIKA 5A6DA 2NTIC 3TBLA 1RWZA 4L60A 3G65C 1YYPA 3V61B 3G65B 4L6PA 1U76A 5IWDA 2ZVLA 1VYJA 2ZVVA 3P87A 3K4XA 2IO4A 3FDSC 1B77A 3AIZC 5E0UA 2HIIA 5B7OA 3LX1A 5HACA 1U7BA 3P83A 3U60F 3F1WA 1PLRA 5H0TA 3A1JC 2IJXA 3FDSD 3V62B 2NTIB 4HK1A 2Z0LA 2HIKC 5DAIA 4ZTDA 3GGRC 3A2FB 2AWAA 3GPMA 3GGRB 1UL1A 3IFVA 3G65A 4RJFA 1IZ4A 3HI8A
chains in the Genus database with same CATH superfamily
1VYMA 3I2MX 3U61F 2OD8A 2IZOC 1T6LA 3U5ZF 2IZOB 5JNED 5CFKA 5E0TA 5IXAA 4D2GA 2IX2C 2AVTA 2IX2B 3A1JB 5AUJA 3AIZA 1UD9A 3GPNA 2HIKB 3A1JA 2NTIA 4TR6A 3AIXB 1PLQA 5IY4A 3P91A 1CZDA 1RXMA 1AXCA 3GGRA 1W60A 1ISQA 3AIXA 3WGWA 1GE8A 3V60B 5E0VA 2ZVWA 4YHRA 2IO4B 3VKXA 4CS5A 3HSLX 1RXZA 2HIIC 2HIIB 1SXJF 3LX2A 1B8HA 5DA7A 2IX2A 2ZVKA 1DMLA 1IZ5A 2ZVMA 2HIKA 5A6DA 2NTIC 3TBLA 1RWZA 4L60A 3G65C 1YYPA 3V61B 3G65B 4L6PA 1U76A 5IWDA 2ZVLA 1VYJA 2ZVVA 3P87A 3K4XA 2IO4A 3FDSC 1B77A 3AIZC 5E0UA 2HIIA 5B7OA 3LX1A 5HACA 1U7BA 3P83A 3U60F 3F1WA 1PLRA 5H0TA 3A1JC 2IJXA 3FDSD 3V62B 2NTIB 4HK1A 2Z0LA 2HIKC 5DAIA 4ZTDA 3GGRC 3A2FB 2AWAA 3GPMA 3GGRB 1UL1A 3IFVA 3G65A 4RJFA 1IZ4A 3HI8A
chains in the Genus database with same CATH topology
1VYMA 3I2MX 3U61F 2OD8A 2IZOC 1T6LA 3U5ZF 2IZOB 5JNED 5CFKA 5E0TA 5IXAA 4D2GA 2IX2C 2AVTA 2IX2B 3A1JB 5AUJA 3AIZA 1UD9A 3GPNA 2HIKB 3A1JA 2NTIA 4TR6A 3AIXB 1PLQA 5IY4A 3P91A 1CZDA 1RXMA 1AXCA 3GGRA 1W60A 1ISQA 3AIXA 3WGWA 1GE8A 3V60B 5E0VA 2ZVWA 4YHRA 2IO4B 3VKXA 4CS5A 3HSLX 1RXZA 2HIIC 2HIIB 1SXJF 3LX2A 1B8HA 5DA7A 2IX2A 2ZVKA 1DMLA 1IZ5A 2ZVMA 2HIKA 5A6DA 2NTIC 3TBLA 1RWZA 4L60A 3G65C 1YYPA 3V61B 3G65B 4L6PA 1U76A 5IWDA 2ZVLA 1VYJA 2ZVVA 3P87A 3K4XA 2IO4A 3FDSC 1B77A 3AIZC 5E0UA 2HIIA 5B7OA 3LX1A 5HACA 1U7BA 3P83A 3U60F 3F1WA 1PLRA 5H0TA 3A1JC 2IJXA 3FDSD 3V62B 2NTIB 4HK1A 2Z0LA 2HIKC 5DAIA 4ZTDA 3GGRC 3A2FB 2AWAA 3GPMA 3GGRB 1UL1A 3IFVA 3G65A 4RJFA 1IZ4A 3HI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VYM A;  3I2M X;  3U61 F;  2OD8 A;  2IZO C;  1T6L A;  3U5Z F;  2IZO B;  5JNE D;  5CFK A;  5E0T A;  5IXA A;  4D2G A;  2IX2 C;  2AVT A;  2IX2 B;  3A1J B;  5AUJ A;  3AIZ A;  1UD9 A;  3GPN A;  2HIK B;  3A1J A;  2NTI A;  4TR6 A;  3AIX B;  1PLQ A;  5IY4 A;  3P91 A;  1CZD A;  1RXM A;  1AXC A;  3GGR A;  1W60 A;  1ISQ A;  3AIX A;  3WGW A;  1GE8 A;  3V60 B;  5E0V A;  2ZVW A;  4YHR A;  2IO4 B;  3VKX A;  4CS5 A;  3HSL X;  1RXZ A;  2HII C;  2HII B;  1SXJ F;  3LX2 A;  1B8H A;  5DA7 A;  2IX2 A;  2ZVK A;  1DML A;  1IZ5 A;  2ZVM A;  2HIK A;  5A6D A;  2NTI C;  3TBL A;  1RWZ A;  4L60 A;  3G65 C;  1YYP A;  3V61 B;  3G65 B;  4L6P A;  1U76 A;  5IWD A;  2ZVL A;  1VYJ A;  2ZVV A;  3P87 A;  3K4X A;  2IO4 A;  3FDS C;  1B77 A;  3AIZ C;  5E0U A;  2HII A;  5B7O A;  3LX1 A;  5HAC A;  1U7B A;  3P83 A;  3U60 F;  3F1W A;  1PLR A;  5H0T A;  3A1J C;  2IJX A;  3FDS D;  3V62 B;  2NTI B;  4HK1 A;  2Z0L A;  2HIK C;  5DAI A;  4ZTD A;  3GGR C;  3A2F B;  2AWA A;  3GPM A;  3GGR B;  1UL1 A;  3IFV A;  3G65 A;  4RJF A;  1IZ4 A;  3HI8 A; 
#chains in the Genus database with same CATH topology
 1VYM A;  3I2M X;  3U61 F;  2OD8 A;  2IZO C;  1T6L A;  3U5Z F;  2IZO B;  5JNE D;  5CFK A;  5E0T A;  5IXA A;  4D2G A;  2IX2 C;  2AVT A;  2IX2 B;  3A1J B;  5AUJ A;  3AIZ A;  1UD9 A;  3GPN A;  2HIK B;  3A1J A;  2NTI A;  4TR6 A;  3AIX B;  1PLQ A;  5IY4 A;  3P91 A;  1CZD A;  1RXM A;  1AXC A;  3GGR A;  1W60 A;  1ISQ A;  3AIX A;  3WGW A;  1GE8 A;  3V60 B;  5E0V A;  2ZVW A;  4YHR A;  2IO4 B;  3VKX A;  4CS5 A;  3HSL X;  1RXZ A;  2HII C;  2HII B;  1SXJ F;  3LX2 A;  1B8H A;  5DA7 A;  2IX2 A;  2ZVK A;  1DML A;  1IZ5 A;  2ZVM A;  2HIK A;  5A6D A;  2NTI C;  3TBL A;  1RWZ A;  4L60 A;  3G65 C;  1YYP A;  3V61 B;  3G65 B;  4L6P A;  1U76 A;  5IWD A;  2ZVL A;  1VYJ A;  2ZVV A;  3P87 A;  3K4X A;  2IO4 A;  3FDS C;  1B77 A;  3AIZ C;  5E0U A;  2HII A;  5B7O A;  3LX1 A;  5HAC A;  1U7B A;  3P83 A;  3U60 F;  3F1W A;  1PLR A;  5H0T A;  3A1J C;  2IJX A;  3FDS D;  3V62 B;  2NTI B;  4HK1 A;  2Z0L A;  2HIK C;  5DAI A;  4ZTD A;  3GGR C;  3A2F B;  2AWA A;  3GPM A;  3GGR B;  1UL1 A;  3IFV A;  3G65 A;  4RJF A;  1IZ4 A;  3HI8 A; 
#chains in the Genus database with same CATH homology
 1VYM A;  3I2M X;  3U61 F;  2OD8 A;  2IZO C;  1T6L A;  3U5Z F;  2IZO B;  5JNE D;  5CFK A;  5E0T A;  5IXA A;  4D2G A;  2IX2 C;  2AVT A;  2IX2 B;  3A1J B;  5AUJ A;  3AIZ A;  1UD9 A;  3GPN A;  2HIK B;  3A1J A;  2NTI A;  4TR6 A;  3AIX B;  1PLQ A;  5IY4 A;  3P91 A;  1CZD A;  1RXM A;  1AXC A;  3GGR A;  1W60 A;  1ISQ A;  3AIX A;  3WGW A;  1GE8 A;  3V60 B;  5E0V A;  2ZVW A;  4YHR A;  2IO4 B;  3VKX A;  4CS5 A;  3HSL X;  1RXZ A;  2HII C;  2HII B;  1SXJ F;  3LX2 A;  1B8H A;  5DA7 A;  2IX2 A;  2ZVK A;  1DML A;  1IZ5 A;  2ZVM A;  2HIK A;  5A6D A;  2NTI C;  3TBL A;  1RWZ A;  4L60 A;  3G65 C;  1YYP A;  3V61 B;  3G65 B;  4L6P A;  1U76 A;  5IWD A;  2ZVL A;  1VYJ A;  2ZVV A;  3P87 A;  3K4X A;  2IO4 A;  3FDS C;  1B77 A;  3AIZ C;  5E0U A;  2HII A;  5B7O A;  3LX1 A;  5HAC A;  1U7B A;  3P83 A;  3U60 F;  3F1W A;  1PLR A;  5H0T A;  3A1J C;  2IJX A;  3FDS D;  3V62 B;  2NTI B;  4HK1 A;  2Z0L A;  2HIK C;  5DAI A;  4ZTD A;  3GGR C;  3A2F B;  2AWA A;  3GPM A;  3GGR B;  1UL1 A;  3IFV A;  3G65 A;  4RJF A;  1IZ4 A;  3HI8 A; 
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