3TBL | Genus

Total Genus 59

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	59
sequence length	256
structure length	250
Chain Sequence	MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Replication
source organism	Homo sapiens
publication title	Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation. pubmed doi rcsb
molecule keywords	Proliferating cell nuclear antigen
total genus	59
structure length	250
sequence length	256
chains with identical sequence	B, C
ec nomenclature
pdb deposition date	2011-08-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00705	PCNA_N	Proliferating cell nuclear antigen, N-terminal domain
A	PF02747	PCNA_C	Proliferating cell nuclear antigen, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	3tblA00

5AUJA 1VYJA 2HIKC 3LX2A 3IFVA 1PLRA 2ZVWA 5E0UA 2HIIA 3P83A 2IO4A 3GGRB 3A1JC 1SXJF 2ZVKA 1U7BA 2IZOB 2NTIC 3GPNA 3HSLX 4YHRA 5A6DA 5IXAA 2IJXA 2ZVLA 5H0TA 1IZ4A 5HACA 3G65B 2HIIB 3U60F 3AIXB 5E0VA 3FDSC 5B7OA 2IO4B 5CFKA 4RJFA 1YYPA 3G65A 3AIZC 3AIXA 1U76A 3HI8A 3K4XA 4TR6A 2HIKB 1IZ5A 3V60B 3LX1A 1UD9A 3GPMA 3WGWA 2HIKA 2IX2C 5E0TA 1W60A 5DA7A 3A1JB 5DAIA 1B8HA 2OD8A 5IWDA 1CZDA 4CS5A 2Z0LA 2NTIB 3A1JA 1UL1A 1ISQA 2HIIC 2NTIA 1GE8A 2IX2A 2AWAA 1RXZA 3U61F 3V62B 3GGRC 4ZTDA 1T6LA 5IY4A 2IZOC 5JNED 1RXMA 2AVTA 4L60A 2ZVVA 3VKXA 3AIZA 3FDSD 1VYMA 3P87A 1PLQA 3F1WA 3I2MX 3V61B 3A2FB 3G65C 2IX2B 2ZVMA 1B77A 3GGRA 3TBLA 1AXCA 1DMLA 3P91A 3U5ZF 4L6PA 4D2GA 1RWZA 4HK1A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5AUJ A;  1VYJ A;  2HIK C;  3LX2 A;  3IFV A;  1PLR A;  2ZVW A;  5E0U A;  2HII A;  3P83 A;  2IO4 A;  3GGR B;  3A1J C;  1SXJ F;  2ZVK A;  1U7B A;  2IZO B;  2NTI C;  3GPN A;  3HSL X;  4YHR A;  5A6D A;  5IXA A;  2IJX A;  2ZVL A;  5H0T A;  1IZ4 A;  5HAC A;  3G65 B;  2HII B;  3U60 F;  3AIX B;  5E0V A;  3FDS C;  5B7O A;  2IO4 B;  5CFK A;  4RJF A;  1YYP A;  3G65 A;  3AIZ C;  3AIX A;  1U76 A;  3HI8 A;  3K4X A;  4TR6 A;  2HIK B;  1IZ5 A;  3V60 B;  3LX1 A;  1UD9 A;  3GPM A;  3WGW A;  2HIK A;  2IX2 C;  5E0T A;  1W60 A;  5DA7 A;  3A1J B;  5DAI A;  1B8H A;  2OD8 A;  5IWD A;  1CZD A;  4CS5 A;  2Z0L A;  2NTI B;  3A1J A;  1UL1 A;  1ISQ A;  2HII C;  2NTI A;  1GE8 A;  2IX2 A;  2AWA A;  1RXZ A;  3U61 F;  3V62 B;  3GGR C;  4ZTD A;  1T6L A;  5IY4 A;  2IZO C;  5JNE D;  1RXM A;  2AVT A;  4L60 A;  2ZVV A;  3VKX A;  3AIZ A;  3FDS D;  1VYM A;  3P87 A;  1PLQ A;  3F1W A;  3I2M X;  3V61 B;  3A2F B;  3G65 C;  2IX2 B;  2ZVM A;  1B77 A;  3GGR A;  3TBL A;  1AXC A;  1DML A;  3P91 A;  3U5Z F;  4L6P A;  4D2G A;  1RWZ A;  4HK1 A; 
#chains in the Genus database with same CATH topology
 5AUJ A;  1VYJ A;  2HIK C;  3LX2 A;  3IFV A;  1PLR A;  2ZVW A;  5E0U A;  2HII A;  3P83 A;  2IO4 A;  3GGR B;  3A1J C;  1SXJ F;  2ZVK A;  1U7B A;  2IZO B;  2NTI C;  3GPN A;  3HSL X;  4YHR A;  5A6D A;  5IXA A;  2IJX A;  2ZVL A;  5H0T A;  1IZ4 A;  5HAC A;  3G65 B;  2HII B;  3U60 F;  3AIX B;  5E0V A;  3FDS C;  5B7O A;  2IO4 B;  5CFK A;  4RJF A;  1YYP A;  3G65 A;  3AIZ C;  3AIX A;  1U76 A;  3HI8 A;  3K4X A;  4TR6 A;  2HIK B;  1IZ5 A;  3V60 B;  3LX1 A;  1UD9 A;  3GPM A;  3WGW A;  2HIK A;  2IX2 C;  5E0T A;  1W60 A;  5DA7 A;  3A1J B;  5DAI A;  1B8H A;  2OD8 A;  5IWD A;  1CZD A;  4CS5 A;  2Z0L A;  2NTI B;  3A1J A;  1UL1 A;  1ISQ A;  2HII C;  2NTI A;  1GE8 A;  2IX2 A;  2AWA A;  1RXZ A;  3U61 F;  3V62 B;  3GGR C;  4ZTD A;  1T6L A;  5IY4 A;  2IZO C;  5JNE D;  1RXM A;  2AVT A;  4L60 A;  2ZVV A;  3VKX A;  3AIZ A;  3FDS D;  1VYM A;  3P87 A;  1PLQ A;  3F1W A;  3I2M X;  3V61 B;  3A2F B;  3G65 C;  2IX2 B;  2ZVM A;  1B77 A;  3GGR A;  3TBL A;  1AXC A;  1DML A;  3P91 A;  3U5Z F;  4L6P A;  4D2G A;  1RWZ A;  4HK1 A; 
#chains in the Genus database with same CATH homology
 5AUJ A;  1VYJ A;  2HIK C;  3LX2 A;  3IFV A;  1PLR A;  2ZVW A;  5E0U A;  2HII A;  3P83 A;  2IO4 A;  3GGR B;  3A1J C;  1SXJ F;  2ZVK A;  1U7B A;  2IZO B;  2NTI C;  3GPN A;  3HSL X;  4YHR A;  5A6D A;  5IXA A;  2IJX A;  2ZVL A;  5H0T A;  1IZ4 A;  5HAC A;  3G65 B;  2HII B;  3U60 F;  3AIX B;  5E0V A;  3FDS C;  5B7O A;  2IO4 B;  5CFK A;  4RJF A;  1YYP A;  3G65 A;  3AIZ C;  3AIX A;  1U76 A;  3HI8 A;  3K4X A;  4TR6 A;  2HIK B;  1IZ5 A;  3V60 B;  3LX1 A;  1UD9 A;  3GPM A;  3WGW A;  2HIK A;  2IX2 C;  5E0T A;  1W60 A;  5DA7 A;  3A1J B;  5DAI A;  1B8H A;  2OD8 A;  5IWD A;  1CZD A;  4CS5 A;  2Z0L A;  2NTI B;  3A1J A;  1UL1 A;  1ISQ A;  2HII C;  2NTI A;  1GE8 A;  2IX2 A;  2AWA A;  1RXZ A;  3U61 F;  3V62 B;  3GGR C;  4ZTD A;  1T6L A;  5IY4 A;  2IZO C;  5JNE D;  1RXM A;  2AVT A;  4L60 A;  2ZVV A;  3VKX A;  3AIZ A;  3FDS D;  1VYM A;  3P87 A;  1PLQ A;  3F1W A;  3I2M X;  3V61 B;  3A2F B;  3G65 C;  2IX2 B;  2ZVM A;  1B77 A;  3GGR A;  3TBL A;  1AXC A;  1DML A;  3P91 A;  3U5Z F;  4L6P A;  4D2G A;  1RWZ A;  4HK1 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3TBLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations