3A2FB

Crystal structure of pyrococcus furiosus dna polymerase/pcna monomer mutant complex
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
247
structure length
247
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEEMEVDLPELPFTAKVVVLGEVLKAAVKAASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex
rcsb
molecule tags Transferase/replication
source organism Pyrococcus furiosus
molecule keywords DNA polymerase
total genus 52
structure length 247
sequence length 247
ec nomenclature
pdb deposition date 2009-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
B PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3a2fB00
1IZ4A 3FDSD 1U7BA 1B8HA 3A1JA 1CZDA 2IX2C 2IO4A 2NTIA 2ZVKA 2HIKB 3A2FB 1GE8A 5H0TA 3K4XA 5CFKA 3I2MX 2ZVMA 5AUJA 3GPNA 2HIIB 3HSLX 2Z0LA 3HI8A 3VKXA 3F1WA 3P83A 3G65A 3AIXB 4TR6A 4L60A 1RWZA 1U76A 2IX2B 1RXZA 3GPMA 3A1JC 1UL1A 2IJXA 1UD9A 5IY4A 5DAIA 3U5ZF 3LX2A 2ZVWA 5JNED 3AIZA 3TBLA 3FDSC 3P91A 3U61F 5IWDA 3G65C 1RXMA 5IXAA 3GGRB 3GGRC 5E0VA 1AXCA 3A1JB 2IO4B 3LX1A 2NTIB 4L6PA 1T6LA 3U60F 2NTIC 2HIKA 1YYPA 4HK1A 1VYJA 1VYMA 3WGWA 2ZVLA 2HIIA 3AIZC 2ZVVA 3V61B 3G65B 5HACA 3AIXA 1W60A 5E0UA 2IZOC 4ZTDA 4CS5A 1PLQA 2IX2A 1SXJF 5A6DA 2AWAA 1DMLA 3P87A 1ISQA 1IZ5A 2OD8A 2HIKC 5B7OA 1B77A 3IFVA 3V62B 1PLRA 5E0TA 4D2GA 2HIIC 5DA7A 2AVTA 4RJFA 3V60B 4YHRA 2IZOB 3GGRA
chains in the Genus database with same CATH superfamily
1IZ4A 3FDSD 1U7BA 1B8HA 3A1JA 1CZDA 2IX2C 2IO4A 2NTIA 2ZVKA 2HIKB 3A2FB 1GE8A 5H0TA 3K4XA 5CFKA 3I2MX 2ZVMA 5AUJA 3GPNA 2HIIB 3HSLX 2Z0LA 3HI8A 3VKXA 3F1WA 3P83A 3G65A 3AIXB 4TR6A 4L60A 1RWZA 1U76A 2IX2B 1RXZA 3GPMA 3A1JC 1UL1A 2IJXA 1UD9A 5IY4A 5DAIA 3U5ZF 3LX2A 2ZVWA 5JNED 3AIZA 3TBLA 3FDSC 3P91A 3U61F 5IWDA 3G65C 1RXMA 5IXAA 3GGRB 3GGRC 5E0VA 1AXCA 3A1JB 2IO4B 3LX1A 2NTIB 4L6PA 1T6LA 3U60F 2NTIC 2HIKA 1YYPA 4HK1A 1VYJA 1VYMA 3WGWA 2ZVLA 2HIIA 3AIZC 2ZVVA 3V61B 3G65B 5HACA 3AIXA 1W60A 5E0UA 2IZOC 4ZTDA 4CS5A 1PLQA 2IX2A 1SXJF 5A6DA 2AWAA 1DMLA 3P87A 1ISQA 1IZ5A 2OD8A 2HIKC 5B7OA 1B77A 3IFVA 3V62B 1PLRA 5E0TA 4D2GA 2HIIC 5DA7A 2AVTA 4RJFA 3V60B 4YHRA 2IZOB 3GGRA
chains in the Genus database with same CATH topology
1IZ4A 3FDSD 1U7BA 1B8HA 3A1JA 1CZDA 2IX2C 2IO4A 2NTIA 2ZVKA 2HIKB 3A2FB 1GE8A 5H0TA 3K4XA 5CFKA 3I2MX 2ZVMA 5AUJA 3GPNA 2HIIB 3HSLX 2Z0LA 3HI8A 3VKXA 3F1WA 3P83A 3G65A 3AIXB 4TR6A 4L60A 1RWZA 1U76A 2IX2B 1RXZA 3GPMA 3A1JC 1UL1A 2IJXA 1UD9A 5IY4A 5DAIA 3U5ZF 3LX2A 2ZVWA 5JNED 3AIZA 3TBLA 3FDSC 3P91A 3U61F 5IWDA 3G65C 1RXMA 5IXAA 3GGRB 3GGRC 5E0VA 1AXCA 3A1JB 2IO4B 3LX1A 2NTIB 4L6PA 1T6LA 3U60F 2NTIC 2HIKA 1YYPA 4HK1A 1VYJA 1VYMA 3WGWA 2ZVLA 2HIIA 3AIZC 2ZVVA 3V61B 3G65B 5HACA 3AIXA 1W60A 5E0UA 2IZOC 4ZTDA 4CS5A 1PLQA 2IX2A 1SXJF 5A6DA 2AWAA 1DMLA 3P87A 1ISQA 1IZ5A 2OD8A 2HIKC 5B7OA 1B77A 3IFVA 3V62B 1PLRA 5E0TA 4D2GA 2HIIC 5DA7A 2AVTA 4RJFA 3V60B 4YHRA 2IZOB 3GGRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IZ4 A;  3FDS D;  1U7B A;  1B8H A;  3A1J A;  1CZD A;  2IX2 C;  2IO4 A;  2NTI A;  2ZVK A;  2HIK B;  3A2F B;  1GE8 A;  5H0T A;  3K4X A;  5CFK A;  3I2M X;  2ZVM A;  5AUJ A;  3GPN A;  2HII B;  3HSL X;  2Z0L A;  3HI8 A;  3VKX A;  3F1W A;  3P83 A;  3G65 A;  3AIX B;  4TR6 A;  4L60 A;  1RWZ A;  1U76 A;  2IX2 B;  1RXZ A;  3GPM A;  3A1J C;  1UL1 A;  2IJX A;  1UD9 A;  5IY4 A;  5DAI A;  3U5Z F;  3LX2 A;  2ZVW A;  5JNE D;  3AIZ A;  3TBL A;  3FDS C;  3P91 A;  3U61 F;  5IWD A;  3G65 C;  1RXM A;  5IXA A;  3GGR B;  3GGR C;  5E0V A;  1AXC A;  3A1J B;  2IO4 B;  3LX1 A;  2NTI B;  4L6P A;  1T6L A;  3U60 F;  2NTI C;  2HIK A;  1YYP A;  4HK1 A;  1VYJ A;  1VYM A;  3WGW A;  2ZVL A;  2HII A;  3AIZ C;  2ZVV A;  3V61 B;  3G65 B;  5HAC A;  3AIX A;  1W60 A;  5E0U A;  2IZO C;  4ZTD A;  4CS5 A;  1PLQ A;  2IX2 A;  1SXJ F;  5A6D A;  2AWA A;  1DML A;  3P87 A;  1ISQ A;  1IZ5 A;  2OD8 A;  2HIK C;  5B7O A;  1B77 A;  3IFV A;  3V62 B;  1PLR A;  5E0T A;  4D2G A;  2HII C;  5DA7 A;  2AVT A;  4RJF A;  3V60 B;  4YHR A;  2IZO B;  3GGR A; 
#chains in the Genus database with same CATH topology
 1IZ4 A;  3FDS D;  1U7B A;  1B8H A;  3A1J A;  1CZD A;  2IX2 C;  2IO4 A;  2NTI A;  2ZVK A;  2HIK B;  3A2F B;  1GE8 A;  5H0T A;  3K4X A;  5CFK A;  3I2M X;  2ZVM A;  5AUJ A;  3GPN A;  2HII B;  3HSL X;  2Z0L A;  3HI8 A;  3VKX A;  3F1W A;  3P83 A;  3G65 A;  3AIX B;  4TR6 A;  4L60 A;  1RWZ A;  1U76 A;  2IX2 B;  1RXZ A;  3GPM A;  3A1J C;  1UL1 A;  2IJX A;  1UD9 A;  5IY4 A;  5DAI A;  3U5Z F;  3LX2 A;  2ZVW A;  5JNE D;  3AIZ A;  3TBL A;  3FDS C;  3P91 A;  3U61 F;  5IWD A;  3G65 C;  1RXM A;  5IXA A;  3GGR B;  3GGR C;  5E0V A;  1AXC A;  3A1J B;  2IO4 B;  3LX1 A;  2NTI B;  4L6P A;  1T6L A;  3U60 F;  2NTI C;  2HIK A;  1YYP A;  4HK1 A;  1VYJ A;  1VYM A;  3WGW A;  2ZVL A;  2HII A;  3AIZ C;  2ZVV A;  3V61 B;  3G65 B;  5HAC A;  3AIX A;  1W60 A;  5E0U A;  2IZO C;  4ZTD A;  4CS5 A;  1PLQ A;  2IX2 A;  1SXJ F;  5A6D A;  2AWA A;  1DML A;  3P87 A;  1ISQ A;  1IZ5 A;  2OD8 A;  2HIK C;  5B7O A;  1B77 A;  3IFV A;  3V62 B;  1PLR A;  5E0T A;  4D2G A;  2HII C;  5DA7 A;  2AVT A;  4RJF A;  3V60 B;  4YHR A;  2IZO B;  3GGR A; 
#chains in the Genus database with same CATH homology
 1IZ4 A;  3FDS D;  1U7B A;  1B8H A;  3A1J A;  1CZD A;  2IX2 C;  2IO4 A;  2NTI A;  2ZVK A;  2HIK B;  3A2F B;  1GE8 A;  5H0T A;  3K4X A;  5CFK A;  3I2M X;  2ZVM A;  5AUJ A;  3GPN A;  2HII B;  3HSL X;  2Z0L A;  3HI8 A;  3VKX A;  3F1W A;  3P83 A;  3G65 A;  3AIX B;  4TR6 A;  4L60 A;  1RWZ A;  1U76 A;  2IX2 B;  1RXZ A;  3GPM A;  3A1J C;  1UL1 A;  2IJX A;  1UD9 A;  5IY4 A;  5DAI A;  3U5Z F;  3LX2 A;  2ZVW A;  5JNE D;  3AIZ A;  3TBL A;  3FDS C;  3P91 A;  3U61 F;  5IWD A;  3G65 C;  1RXM A;  5IXA A;  3GGR B;  3GGR C;  5E0V A;  1AXC A;  3A1J B;  2IO4 B;  3LX1 A;  2NTI B;  4L6P A;  1T6L A;  3U60 F;  2NTI C;  2HIK A;  1YYP A;  4HK1 A;  1VYJ A;  1VYM A;  3WGW A;  2ZVL A;  2HII A;  3AIZ C;  2ZVV A;  3V61 B;  3G65 B;  5HAC A;  3AIX A;  1W60 A;  5E0U A;  2IZO C;  4ZTD A;  4CS5 A;  1PLQ A;  2IX2 A;  1SXJ F;  5A6D A;  2AWA A;  1DML A;  3P87 A;  1ISQ A;  1IZ5 A;  2OD8 A;  2HIK C;  5B7O A;  1B77 A;  3IFV A;  3V62 B;  1PLR A;  5E0T A;  4D2G A;  2HII C;  5DA7 A;  2AVT A;  4RJF A;  3V60 B;  4YHR A;  2IZO B;  3GGR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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