3F1WA

Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
254
structure length
254
Chain Sequence
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSSSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis.
pubmed doi rcsb
molecule tags Replication
source organism Saccharomyces cerevisiae
molecule keywords Proliferating cell nuclear antigen
total genus 55
structure length 254
sequence length 254
ec nomenclature
pdb deposition date 2008-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3f1wA00
2IZOB 1W60A 4ZTDA 5DAIA 5JNED 2HIIB 5IY4A 4D2GA 3HSLX 2Z0LA 4L60A 3IFVA 3V61B 4YHRA 5H0TA 3GGRA 5DA7A 5E0UA 4CS5A 2IZOC 1UL1A 2ZVLA 2ZVKA 1IZ4A 3GGRB 5A6DA 3F1WA 1YYPA 5E0VA 2HIKC 1U7BA 2HIKA 1U76A 3U60F 4RJFA 3LX1A 5AUJA 3GGRC 1RWZA 3FDSD 2HIKB 3G65B 5IWDA 1SXJF 2AVTA 3FDSC 1B77A 3GPNA 2NTIB 5HACA 3V60B 2OD8A 2ZVVA 1VYJA 3VKXA 1T6LA 3G65C 3G65A 1CZDA 5CFKA 1B8HA 1PLRA 1UD9A 1GE8A 2NTIC 3A1JB 1ISQA 2NTIA 3LX2A 3WGWA 3I2MX 3V62B 1RXZA 3P87A 1RXMA 1DMLA 2ZVWA 4HK1A 3TBLA 1VYMA 3K4XA 2IX2B 3P83A 3AIZC 4TR6A 3A1JC 3AIZA 3GPMA 3A1JA 2IO4B 1IZ5A 1PLQA 3A2FB 2IJXA 3HI8A 2ZVMA 3AIXA 5B7OA 1AXCA 2IX2C 2AWAA 2IX2A 4L6PA 2HIIC 2HIIA 2IO4A 5IXAA 3U61F 5E0TA 3P91A 3U5ZF 3AIXB
chains in the Genus database with same CATH superfamily
2IZOB 1W60A 4ZTDA 5DAIA 5JNED 2HIIB 5IY4A 4D2GA 3HSLX 2Z0LA 4L60A 3IFVA 3V61B 4YHRA 5H0TA 3GGRA 5DA7A 5E0UA 4CS5A 2IZOC 1UL1A 2ZVLA 2ZVKA 1IZ4A 3GGRB 5A6DA 3F1WA 1YYPA 5E0VA 2HIKC 1U7BA 2HIKA 1U76A 3U60F 4RJFA 3LX1A 5AUJA 3GGRC 1RWZA 3FDSD 2HIKB 3G65B 5IWDA 1SXJF 2AVTA 3FDSC 1B77A 3GPNA 2NTIB 5HACA 3V60B 2OD8A 2ZVVA 1VYJA 3VKXA 1T6LA 3G65C 3G65A 1CZDA 5CFKA 1B8HA 1PLRA 1UD9A 1GE8A 2NTIC 3A1JB 1ISQA 2NTIA 3LX2A 3WGWA 3I2MX 3V62B 1RXZA 3P87A 1RXMA 1DMLA 2ZVWA 4HK1A 3TBLA 1VYMA 3K4XA 2IX2B 3P83A 3AIZC 4TR6A 3A1JC 3AIZA 3GPMA 3A1JA 2IO4B 1IZ5A 1PLQA 3A2FB 2IJXA 3HI8A 2ZVMA 3AIXA 5B7OA 1AXCA 2IX2C 2AWAA 2IX2A 4L6PA 2HIIC 2HIIA 2IO4A 5IXAA 3U61F 5E0TA 3P91A 3U5ZF 3AIXB
chains in the Genus database with same CATH topology
2IZOB 1W60A 4ZTDA 5DAIA 5JNED 2HIIB 5IY4A 4D2GA 3HSLX 2Z0LA 4L60A 3IFVA 3V61B 4YHRA 5H0TA 3GGRA 5DA7A 5E0UA 4CS5A 2IZOC 1UL1A 2ZVLA 2ZVKA 1IZ4A 3GGRB 5A6DA 3F1WA 1YYPA 5E0VA 2HIKC 1U7BA 2HIKA 1U76A 3U60F 4RJFA 3LX1A 5AUJA 3GGRC 1RWZA 3FDSD 2HIKB 3G65B 5IWDA 1SXJF 2AVTA 3FDSC 1B77A 3GPNA 2NTIB 5HACA 3V60B 2OD8A 2ZVVA 1VYJA 3VKXA 1T6LA 3G65C 3G65A 1CZDA 5CFKA 1B8HA 1PLRA 1UD9A 1GE8A 2NTIC 3A1JB 1ISQA 2NTIA 3LX2A 3WGWA 3I2MX 3V62B 1RXZA 3P87A 1RXMA 1DMLA 2ZVWA 4HK1A 3TBLA 1VYMA 3K4XA 2IX2B 3P83A 3AIZC 4TR6A 3A1JC 3AIZA 3GPMA 3A1JA 2IO4B 1IZ5A 1PLQA 3A2FB 2IJXA 3HI8A 2ZVMA 3AIXA 5B7OA 1AXCA 2IX2C 2AWAA 2IX2A 4L6PA 2HIIC 2HIIA 2IO4A 5IXAA 3U61F 5E0TA 3P91A 3U5ZF 3AIXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IZO B;  1W60 A;  4ZTD A;  5DAI A;  5JNE D;  2HII B;  5IY4 A;  4D2G A;  3HSL X;  2Z0L A;  4L60 A;  3IFV A;  3V61 B;  4YHR A;  5H0T A;  3GGR A;  5DA7 A;  5E0U A;  4CS5 A;  2IZO C;  1UL1 A;  2ZVL A;  2ZVK A;  1IZ4 A;  3GGR B;  5A6D A;  3F1W A;  1YYP A;  5E0V A;  2HIK C;  1U7B A;  2HIK A;  1U76 A;  3U60 F;  4RJF A;  3LX1 A;  5AUJ A;  3GGR C;  1RWZ A;  3FDS D;  2HIK B;  3G65 B;  5IWD A;  1SXJ F;  2AVT A;  3FDS C;  1B77 A;  3GPN A;  2NTI B;  5HAC A;  3V60 B;  2OD8 A;  2ZVV A;  1VYJ A;  3VKX A;  1T6L A;  3G65 C;  3G65 A;  1CZD A;  5CFK A;  1B8H A;  1PLR A;  1UD9 A;  1GE8 A;  2NTI C;  3A1J B;  1ISQ A;  2NTI A;  3LX2 A;  3WGW A;  3I2M X;  3V62 B;  1RXZ A;  3P87 A;  1RXM A;  1DML A;  2ZVW A;  4HK1 A;  3TBL A;  1VYM A;  3K4X A;  2IX2 B;  3P83 A;  3AIZ C;  4TR6 A;  3A1J C;  3AIZ A;  3GPM A;  3A1J A;  2IO4 B;  1IZ5 A;  1PLQ A;  3A2F B;  2IJX A;  3HI8 A;  2ZVM A;  3AIX A;  5B7O A;  1AXC A;  2IX2 C;  2AWA A;  2IX2 A;  4L6P A;  2HII C;  2HII A;  2IO4 A;  5IXA A;  3U61 F;  5E0T A;  3P91 A;  3U5Z F;  3AIX B; 
#chains in the Genus database with same CATH topology
 2IZO B;  1W60 A;  4ZTD A;  5DAI A;  5JNE D;  2HII B;  5IY4 A;  4D2G A;  3HSL X;  2Z0L A;  4L60 A;  3IFV A;  3V61 B;  4YHR A;  5H0T A;  3GGR A;  5DA7 A;  5E0U A;  4CS5 A;  2IZO C;  1UL1 A;  2ZVL A;  2ZVK A;  1IZ4 A;  3GGR B;  5A6D A;  3F1W A;  1YYP A;  5E0V A;  2HIK C;  1U7B A;  2HIK A;  1U76 A;  3U60 F;  4RJF A;  3LX1 A;  5AUJ A;  3GGR C;  1RWZ A;  3FDS D;  2HIK B;  3G65 B;  5IWD A;  1SXJ F;  2AVT A;  3FDS C;  1B77 A;  3GPN A;  2NTI B;  5HAC A;  3V60 B;  2OD8 A;  2ZVV A;  1VYJ A;  3VKX A;  1T6L A;  3G65 C;  3G65 A;  1CZD A;  5CFK A;  1B8H A;  1PLR A;  1UD9 A;  1GE8 A;  2NTI C;  3A1J B;  1ISQ A;  2NTI A;  3LX2 A;  3WGW A;  3I2M X;  3V62 B;  1RXZ A;  3P87 A;  1RXM A;  1DML A;  2ZVW A;  4HK1 A;  3TBL A;  1VYM A;  3K4X A;  2IX2 B;  3P83 A;  3AIZ C;  4TR6 A;  3A1J C;  3AIZ A;  3GPM A;  3A1J A;  2IO4 B;  1IZ5 A;  1PLQ A;  3A2F B;  2IJX A;  3HI8 A;  2ZVM A;  3AIX A;  5B7O A;  1AXC A;  2IX2 C;  2AWA A;  2IX2 A;  4L6P A;  2HII C;  2HII A;  2IO4 A;  5IXA A;  3U61 F;  5E0T A;  3P91 A;  3U5Z F;  3AIX B; 
#chains in the Genus database with same CATH homology
 2IZO B;  1W60 A;  4ZTD A;  5DAI A;  5JNE D;  2HII B;  5IY4 A;  4D2G A;  3HSL X;  2Z0L A;  4L60 A;  3IFV A;  3V61 B;  4YHR A;  5H0T A;  3GGR A;  5DA7 A;  5E0U A;  4CS5 A;  2IZO C;  1UL1 A;  2ZVL A;  2ZVK A;  1IZ4 A;  3GGR B;  5A6D A;  3F1W A;  1YYP A;  5E0V A;  2HIK C;  1U7B A;  2HIK A;  1U76 A;  3U60 F;  4RJF A;  3LX1 A;  5AUJ A;  3GGR C;  1RWZ A;  3FDS D;  2HIK B;  3G65 B;  5IWD A;  1SXJ F;  2AVT A;  3FDS C;  1B77 A;  3GPN A;  2NTI B;  5HAC A;  3V60 B;  2OD8 A;  2ZVV A;  1VYJ A;  3VKX A;  1T6L A;  3G65 C;  3G65 A;  1CZD A;  5CFK A;  1B8H A;  1PLR A;  1UD9 A;  1GE8 A;  2NTI C;  3A1J B;  1ISQ A;  2NTI A;  3LX2 A;  3WGW A;  3I2M X;  3V62 B;  1RXZ A;  3P87 A;  1RXM A;  1DML A;  2ZVW A;  4HK1 A;  3TBL A;  1VYM A;  3K4X A;  2IX2 B;  3P83 A;  3AIZ C;  4TR6 A;  3A1J C;  3AIZ A;  3GPM A;  3A1J A;  2IO4 B;  1IZ5 A;  1PLQ A;  3A2F B;  2IJX A;  3HI8 A;  2ZVM A;  3AIX A;  5B7O A;  1AXC A;  2IX2 C;  2AWA A;  2IX2 A;  4L6P A;  2HII C;  2HII A;  2IO4 A;  5IXA A;  3U61 F;  5E0T A;  3P91 A;  3U5Z F;  3AIX B; 
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similar chains in the Genus database (?% sequence similarity)
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