3GPMA

Structure of the trimeric form of the e113g pcna mutant protein
Total Genus 45
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
254
structure length
254
Chain Sequence
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAGYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Saccharomyces cerevisiae
molecule keywords Proliferating cell nuclear antigen
total genus 45
structure length 254
sequence length 254
ec nomenclature
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3gpmA00
3AIXB 5E0VA 2NTIC 1AXCA 3G65B 4HK1A 1RWZA 3AIZC 3FDSC 4TR6A 5H0TA 3GPNA 2AVTA 1UD9A 3GPMA 2IO4A 1VYMA 5E0TA 1CZDA 2HIKA 2IZOB 3P83A 3TBLA 5DAIA 2Z0LA 2IX2A 3A1JC 3GGRC 1T6LA 3K4XA 2IO4B 3A1JA 3GGRA 1IZ5A 2HIKB 5B7OA 3P87A 5IXAA 3HSLX 2NTIA 4RJFA 3V60B 1VYJA 1B8HA 3AIZA 5AUJA 1GE8A 1W60A 1UL1A 3LX1A 2HIIB 3V61B 3F1WA 5E0UA 2NTIB 5JNED 4L6PA 4D2GA 1PLQA 2ZVVA 5A6DA 3U60F 1IZ4A 3G65C 4L60A 5IY4A 3U61F 2IX2B 3P91A 5HACA 3A1JB 3GGRB 2HIIC 2IZOC 2AWAA 2ZVWA 2IJXA 3IFVA 3VKXA 2OD8A 1ISQA 3A2FB 1DMLA 2ZVKA 4YHRA 3WGWA 1PLRA 2ZVLA 1U76A 2HIKC 3I2MX 1RXZA 3AIXA 1SXJF 3V62B 3HI8A 1B77A 3FDSD 1RXMA 3G65A 5CFKA 4ZTDA 5DA7A 2ZVMA 2IX2C 1U7BA 5IWDA 4CS5A 3LX2A 3U5ZF 1YYPA 2HIIA
chains in the Genus database with same CATH superfamily
3AIXB 5E0VA 2NTIC 1AXCA 3G65B 4HK1A 1RWZA 3AIZC 3FDSC 4TR6A 5H0TA 3GPNA 2AVTA 1UD9A 3GPMA 2IO4A 1VYMA 5E0TA 1CZDA 2HIKA 2IZOB 3P83A 3TBLA 5DAIA 2Z0LA 2IX2A 3A1JC 3GGRC 1T6LA 3K4XA 2IO4B 3A1JA 3GGRA 1IZ5A 2HIKB 5B7OA 3P87A 5IXAA 3HSLX 2NTIA 4RJFA 3V60B 1VYJA 1B8HA 3AIZA 5AUJA 1GE8A 1W60A 1UL1A 3LX1A 2HIIB 3V61B 3F1WA 5E0UA 2NTIB 5JNED 4L6PA 4D2GA 1PLQA 2ZVVA 5A6DA 3U60F 1IZ4A 3G65C 4L60A 5IY4A 3U61F 2IX2B 3P91A 5HACA 3A1JB 3GGRB 2HIIC 2IZOC 2AWAA 2ZVWA 2IJXA 3IFVA 3VKXA 2OD8A 1ISQA 3A2FB 1DMLA 2ZVKA 4YHRA 3WGWA 1PLRA 2ZVLA 1U76A 2HIKC 3I2MX 1RXZA 3AIXA 1SXJF 3V62B 3HI8A 1B77A 3FDSD 1RXMA 3G65A 5CFKA 4ZTDA 5DA7A 2ZVMA 2IX2C 1U7BA 5IWDA 4CS5A 3LX2A 3U5ZF 1YYPA 2HIIA
chains in the Genus database with same CATH topology
3AIXB 5E0VA 2NTIC 1AXCA 3G65B 4HK1A 1RWZA 3AIZC 3FDSC 4TR6A 5H0TA 3GPNA 2AVTA 1UD9A 3GPMA 2IO4A 1VYMA 5E0TA 1CZDA 2HIKA 2IZOB 3P83A 3TBLA 5DAIA 2Z0LA 2IX2A 3A1JC 3GGRC 1T6LA 3K4XA 2IO4B 3A1JA 3GGRA 1IZ5A 2HIKB 5B7OA 3P87A 5IXAA 3HSLX 2NTIA 4RJFA 3V60B 1VYJA 1B8HA 3AIZA 5AUJA 1GE8A 1W60A 1UL1A 3LX1A 2HIIB 3V61B 3F1WA 5E0UA 2NTIB 5JNED 4L6PA 4D2GA 1PLQA 2ZVVA 5A6DA 3U60F 1IZ4A 3G65C 4L60A 5IY4A 3U61F 2IX2B 3P91A 5HACA 3A1JB 3GGRB 2HIIC 2IZOC 2AWAA 2ZVWA 2IJXA 3IFVA 3VKXA 2OD8A 1ISQA 3A2FB 1DMLA 2ZVKA 4YHRA 3WGWA 1PLRA 2ZVLA 1U76A 2HIKC 3I2MX 1RXZA 3AIXA 1SXJF 3V62B 3HI8A 1B77A 3FDSD 1RXMA 3G65A 5CFKA 4ZTDA 5DA7A 2ZVMA 2IX2C 1U7BA 5IWDA 4CS5A 3LX2A 3U5ZF 1YYPA 2HIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AIX B;  5E0V A;  2NTI C;  1AXC A;  3G65 B;  4HK1 A;  1RWZ A;  3AIZ C;  3FDS C;  4TR6 A;  5H0T A;  3GPN A;  2AVT A;  1UD9 A;  3GPM A;  2IO4 A;  1VYM A;  5E0T A;  1CZD A;  2HIK A;  2IZO B;  3P83 A;  3TBL A;  5DAI A;  2Z0L A;  2IX2 A;  3A1J C;  3GGR C;  1T6L A;  3K4X A;  2IO4 B;  3A1J A;  3GGR A;  1IZ5 A;  2HIK B;  5B7O A;  3P87 A;  5IXA A;  3HSL X;  2NTI A;  4RJF A;  3V60 B;  1VYJ A;  1B8H A;  3AIZ A;  5AUJ A;  1GE8 A;  1W60 A;  1UL1 A;  3LX1 A;  2HII B;  3V61 B;  3F1W A;  5E0U A;  2NTI B;  5JNE D;  4L6P A;  4D2G A;  1PLQ A;  2ZVV A;  5A6D A;  3U60 F;  1IZ4 A;  3G65 C;  4L60 A;  5IY4 A;  3U61 F;  2IX2 B;  3P91 A;  5HAC A;  3A1J B;  3GGR B;  2HII C;  2IZO C;  2AWA A;  2ZVW A;  2IJX A;  3IFV A;  3VKX A;  2OD8 A;  1ISQ A;  3A2F B;  1DML A;  2ZVK A;  4YHR A;  3WGW A;  1PLR A;  2ZVL A;  1U76 A;  2HIK C;  3I2M X;  1RXZ A;  3AIX A;  1SXJ F;  3V62 B;  3HI8 A;  1B77 A;  3FDS D;  1RXM A;  3G65 A;  5CFK A;  4ZTD A;  5DA7 A;  2ZVM A;  2IX2 C;  1U7B A;  5IWD A;  4CS5 A;  3LX2 A;  3U5Z F;  1YYP A;  2HII A; 
#chains in the Genus database with same CATH topology
 3AIX B;  5E0V A;  2NTI C;  1AXC A;  3G65 B;  4HK1 A;  1RWZ A;  3AIZ C;  3FDS C;  4TR6 A;  5H0T A;  3GPN A;  2AVT A;  1UD9 A;  3GPM A;  2IO4 A;  1VYM A;  5E0T A;  1CZD A;  2HIK A;  2IZO B;  3P83 A;  3TBL A;  5DAI A;  2Z0L A;  2IX2 A;  3A1J C;  3GGR C;  1T6L A;  3K4X A;  2IO4 B;  3A1J A;  3GGR A;  1IZ5 A;  2HIK B;  5B7O A;  3P87 A;  5IXA A;  3HSL X;  2NTI A;  4RJF A;  3V60 B;  1VYJ A;  1B8H A;  3AIZ A;  5AUJ A;  1GE8 A;  1W60 A;  1UL1 A;  3LX1 A;  2HII B;  3V61 B;  3F1W A;  5E0U A;  2NTI B;  5JNE D;  4L6P A;  4D2G A;  1PLQ A;  2ZVV A;  5A6D A;  3U60 F;  1IZ4 A;  3G65 C;  4L60 A;  5IY4 A;  3U61 F;  2IX2 B;  3P91 A;  5HAC A;  3A1J B;  3GGR B;  2HII C;  2IZO C;  2AWA A;  2ZVW A;  2IJX A;  3IFV A;  3VKX A;  2OD8 A;  1ISQ A;  3A2F B;  1DML A;  2ZVK A;  4YHR A;  3WGW A;  1PLR A;  2ZVL A;  1U76 A;  2HIK C;  3I2M X;  1RXZ A;  3AIX A;  1SXJ F;  3V62 B;  3HI8 A;  1B77 A;  3FDS D;  1RXM A;  3G65 A;  5CFK A;  4ZTD A;  5DA7 A;  2ZVM A;  2IX2 C;  1U7B A;  5IWD A;  4CS5 A;  3LX2 A;  3U5Z F;  1YYP A;  2HII A; 
#chains in the Genus database with same CATH homology
 3AIX B;  5E0V A;  2NTI C;  1AXC A;  3G65 B;  4HK1 A;  1RWZ A;  3AIZ C;  3FDS C;  4TR6 A;  5H0T A;  3GPN A;  2AVT A;  1UD9 A;  3GPM A;  2IO4 A;  1VYM A;  5E0T A;  1CZD A;  2HIK A;  2IZO B;  3P83 A;  3TBL A;  5DAI A;  2Z0L A;  2IX2 A;  3A1J C;  3GGR C;  1T6L A;  3K4X A;  2IO4 B;  3A1J A;  3GGR A;  1IZ5 A;  2HIK B;  5B7O A;  3P87 A;  5IXA A;  3HSL X;  2NTI A;  4RJF A;  3V60 B;  1VYJ A;  1B8H A;  3AIZ A;  5AUJ A;  1GE8 A;  1W60 A;  1UL1 A;  3LX1 A;  2HII B;  3V61 B;  3F1W A;  5E0U A;  2NTI B;  5JNE D;  4L6P A;  4D2G A;  1PLQ A;  2ZVV A;  5A6D A;  3U60 F;  1IZ4 A;  3G65 C;  4L60 A;  5IY4 A;  3U61 F;  2IX2 B;  3P91 A;  5HAC A;  3A1J B;  3GGR B;  2HII C;  2IZO C;  2AWA A;  2ZVW A;  2IJX A;  3IFV A;  3VKX A;  2OD8 A;  1ISQ A;  3A2F B;  1DML A;  2ZVK A;  4YHR A;  3WGW A;  1PLR A;  2ZVL A;  1U76 A;  2HIK C;  3I2M X;  1RXZ A;  3AIX A;  1SXJ F;  3V62 B;  3HI8 A;  1B77 A;  3FDS D;  1RXM A;  3G65 A;  5CFK A;  4ZTD A;  5DA7 A;  2ZVM A;  2IX2 C;  1U7B A;  5IWD A;  4CS5 A;  3LX2 A;  3U5Z F;  1YYP A;  2HII A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...